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62666-20-0,MFCD01740869
Catalog No.:AA00EAUT

62666-20-0 | Progabide

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
95%
1 week  
$111.00   $78.00
- +
10mg
95%
1 week  
$149.00   $104.00
- +
25mg
95%
1 week  
$244.00   $171.00
- +
50mg
95%
1 week  
$358.00   $251.00
- +
100mg
95%
1 week  
$530.00   $371.00
- +
200mg
95%
1 week  
$732.00   $512.00
- +
500mg
95%
1 week  
$1,135.00   $795.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00EAUT
Chemical Name:
Progabide
CAS Number:
62666-20-0
Molecular Formula:
C17H16ClFN2O2
Molecular Weight:
334.7725
MDL Number:
MFCD01740869
SMILES:
NC(=O)CCC/N=C(\c1cc(F)ccc1O)/c1ccc(cc1)Cl
Properties
Computed Properties
 
Complexity:
425  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
23  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
6  
XLogP3:
3  

Literature

Title: Stiripentol: an example of antiepileptic drug development in childhood epilepsies.

Journal: European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20120901

Title: [11C]flumazenil binding is increased in a dose-dependent manner with tiagabine-induced elevations in GABA levels.

Journal: PloS one 20120101

Title: Working covariance model selection for generalized estimating equations.

Journal: Statistics in medicine 20111120

Title: Antiepileptic drug discovery: does mechanism of action matter?

Journal: Epilepsy & behavior : E&B 20110801

Title: Prognostic prediction in patients with hip fracture: risk factors predicting difficulties with discharge to own home.

Journal: Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology 20110601

Title: Gamma-aminobutyric acid agonists for neuroleptic-induced tardive dyskinesia.

Journal: The Cochrane database of systematic reviews 20110413

Title: Inference on the rate ratio of recurrent events for the matched pairs design.

Journal: Statistics in medicine 20101230

Title: Pharmacological Review on Centella asiatica: A Potential Herbal Cure-all.

Journal: Indian journal of pharmaceutical sciences 20100101

Title: Quadratic inference functions in marginal models for longitudinal data.

Journal: Statistics in medicine 20091220

Title: Truly 'rational' polytherapy: maximizing efficacy and minimizing drug interactions, drug load, and adverse effects.

Journal: Current neuropharmacology 20090601

Title: Effects of new antiepileptic drugs and progabide on the mitogen-induced proliferative activity of mouse splenocytes.

Journal: Pharmacological reports : PR 20080101

Title: Effects of some new antiepileptic drugs and progabide on glucocorticoid receptor-mediated gene transcription in LMCAT cells.

Journal: Pharmacological reports : PR 20070101

Title: Psychopharmacology of topiramate: from epilepsy to bipolar disorder.

Journal: Neuropsychiatric disease and treatment 20061201

Title: Robust estimating functions and bias correction for longitudinal data analysis.

Journal: Biometrics 20050901

Title: How to appraise the effectiveness of treatment.

Journal: World journal of surgery 20050501

Title: Combined discriminative stimulus effects of midazolam with other positive GABAA modulators and GABAA receptor agonists in rhesus monkeys.

Journal: Psychopharmacology 20050401

Title: Gamma-aminobutyric acid agonists for neuroleptic-induced tardive dyskinesia.

Journal: The Cochrane database of systematic reviews 20041018

Title: [Endoscopic mucosal resection in the upper and lower GI tract].

Journal: Deutsche medizinische Wochenschrift (1946) 20040903

Title: Hypothesis testing in semiparametric additive mixed models.

Journal: Biostatistics (Oxford, England) 20030101

Title: Selection effects in randomized trials with count data.

Journal: Statistics in medicine 20020227

Title: Rat models of genetic absence epilepsy: what do EEG spike-wave discharges tell us about drug effects?

Journal: Methods and findings in experimental and clinical pharmacology 20020101

Title: Gamma-aminobutyric acid agonists for neuroleptic-induced tardive dyskinesia.

Journal: The Cochrane database of systematic reviews 20010101

Title: [Autosomal dominant hereditary distal myopathy linked to chromosome 14].

Journal: Ryoikibetsu shokogun shirizu 20010101

Title: Preclinical evaluation of newly approved and potential antiepileptic drugs against cocaine-induced seizures.

Journal: The Journal of pharmacology and experimental therapeutics 19990901

Title: In vivo and in vitro correlation of microsomal epoxide hydrolase inhibition by progabide.

Journal: Clinical pharmacology and therapeutics 19931101

Title: Co-administration of progabide inhibits haloperidol-induced oral dyskinesias in rats.

Journal: European journal of pharmacology 19920225

Title: GABAergic modulation of lindane (gamma-hexachlorocyclohexane)-induced seizures.

Journal: Toxicology and applied pharmacology 19890801

Title: Therapeutic response to progabide in neuroleptic- and L-dopa-induced dyskinesias.

Journal: Clinical neuropharmacology 19870601

Title: GABA receptor agonists and extrapyramidal motor function: therapeutic implications for Parkinson's disease.

Journal: Advances in neurology 19870101

Title: Anticonvulsant profile of drugs which facilitate GABAergic transmission on convulsions mediated by a GABAergic mechanism.

Journal: Neuropharmacology 19860201

Title: Clinical activity of GABA agonists in neuroleptic- and L-dopa-induced dyskinesia.

Journal: Psychopharmacology. Supplementum 19850101

Title: Pharmacology of the GABAergic system: effects of progabide, a GABA receptor agonist.

Journal: Psychoneuroendocrinology 19840101

Title: Biphasic effects of direct, but not indirect, GABA mimetics and antagonists on haloperidol-induced catalepsy.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 19800301

Title: Effect of the new gamma-aminobutyric acid agonist SL 76 002 on striatal acetylcholine: relation to neuroleptic-induced extrapyramidal alterations.

Journal: Advances in biochemical psychopharmacology 19800101

Title: Biphasic effect of direct GABA mimetic drugs on haloperidol-induced catalepsy [proceedings].

Journal: British journal of pharmacology 19791101

Title: [Potential therapeutic activity of GABA-mimetic drugs in neuropsychiatry].

Journal: Schweizer Archiv fur Neurologie, Neurochirurgie und Psychiatrie = Archives suisses de neurologie, neurochirurgie et de psychiatrie 19790101

Title: Manev H, et al. Progabide, a GABA mimetic drug, stimulates the secretion of plasma corticosterone in rats. Pharmacol Biochem Behav. 1987 Dec;28(4):443-6.

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