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637-84-3,MFCD00008129
Catalog No.:AA003ULW

637-84-3 | Tetraglycine

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Purity
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250mg
95%
in stock  
$65.00   $45.00
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1g
95%
in stock  
$153.00   $108.00
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5g
≥ 98% (HPLC)
in stock  
$527.00   $369.00
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25g
98%
in stock  
$2,505.00   $1,754.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003ULW
Chemical Name:
Tetraglycine
CAS Number:
637-84-3
Molecular Formula:
C8H14N4O5
Molecular Weight:
246.2206
MDL Number:
MFCD00008129
SMILES:
NCC(=O)NCC(=O)NCC(=O)NCC(=O)O
NSC Number:
89178
Properties
Properties
 
BP:
389.22°C (rough estimate)  
Form:
Solid  
MP:
300 °C  
Refractive Index:
1.6590 (estimate)  
Storage:
-20 ℃;  

Computed Properties
 
Complexity:
317  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
17  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
5  
Rotatable Bond Count:
7  
XLogP3:
-4.2  

Downstream Synthesis Route
637-84-3    5680-86-4   
C28H33N5O10 

[1]Patent:WO2019/126691,2019,A1.Locationinpatent:Paragraph01246;01248

Literature

Title: Elucidation of structural and functional integration of a novel antimicrobial peptide from Antheraea mylitta.

Journal: Bioorganic & medicinal chemistry letters 20170415

Title: Structure of the [M + H - H2O]+ ion from tetraglycine: a revisit by means of density functional theory and isotope labeling.

Journal: The journal of physical chemistry. A 20110623

Title: A combined effective fragment potential-fragment molecular orbital method. II. Analytic gradient and application to the geometry optimization of solvated tetraglycine and chignolin.

Journal: The Journal of chemical physics 20110121

Title: Interactions of TRIS [tris(hydroxymethyl)aminomethane] and related buffers with peptide backbone: thermodynamic characterization.

Journal: Physical chemistry chemical physics : PCCP 20101021

Title: Structure of [M + H - H(2)O](+) from protonated tetraglycine revealed by tandem mass spectrometry and IRMPD spectroscopy.

Journal: The journal of physical chemistry. A 20100422

Title: Coordination of (glycyl)(n)glycine (n = 1-3) to Co+ and Co2+.

Journal: The journal of physical chemistry. A 20090806

Title: Synthesis of chimeric tetrapeptide-linked cholic acid derivatives: impending synergistic agents.

Journal: Bioorganic & medicinal chemistry letters 20081015

Title: DNA damage and 2'-deoxyguanosine oxidation induced by S(IV) autoxidation catalyzed by copper(II) tetraglycine complexes: synergistic effect of a second metal ion.

Journal: Journal of inorganic biochemistry 20070501

Title: Copper-induced oligomerization of peptides: a model study.

Journal: European journal of mass spectrometry (Chichester, England) 20070101

Title: Isotope labeling and theoretical study of the formation of a3* ions from protonated tetraglycine.

Journal: Journal of the American Society for Mass Spectrometry 20061201

Title: Solid-state IR-LD spectroscopic and theoretical analysis of glycine-containing peptides and their hydrochlorides.

Journal: Biopolymers 20060815

Title: Human PEPT1 pharmacophore distinguishes between dipeptide transport and binding.

Journal: Journal of medicinal chemistry 20060615

Title: DNA damage induced by sulfite autoxidation catalyzed by copper(II) tetraglycine complexes.

Journal: Dalton transactions (Cambridge, England : 2003) 20050321

Title: Chemiluminescent reaction of sulphite auto-oxidation in the presence of Ni(II)/tetraglycine and ruthenium(II)/bipy complexes: mechanistic considerations.

Journal: Luminescence : the journal of biological and chemical luminescence 20050101

Title: Synergistic effect of Ni(II) and Co(II) ions on the sulfite induced autoxidation of Cu(II)/tetraglycine complex.

Journal: Dalton transactions (Cambridge, England : 2003) 20040707

Title: Contribution of organic anion transporting polypeptide OATP-C to hepatic elimination of the opioid pentapeptide analogue [D-Ala2, D-Leu5]-enkephalin.

Journal: The Journal of pharmacy and pharmacology 20030701

Title: The effect of disorder on the chemical reactivity of an organic solid, tetraglycine methyl ester: change of the reaction mechanism.

Journal: Journal of pharmaceutical sciences 20020201

Title: Metabolism of tetraglycine in isolated non-filtering rat kidneys.

Journal: Research communications in molecular pathology and pharmacology 20020101

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