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637-96-7,MFCD00012609
Catalog No.:AA003U4L

637-96-7 | Sarcosine hydrochloride

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Purity
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25g
95%
in stock  
$23.00   $16.00
- +
100g
95%
in stock  
$71.00   $50.00
- +
500g
95%
in stock  
$260.00   $182.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003U4L
Chemical Name:
Sarcosine hydrochloride
CAS Number:
637-96-7
Molecular Formula:
C3H8ClNO2
Molecular Weight:
125.5541
MDL Number:
MFCD00012609
SMILES:
CNCC(=O)O.Cl
Properties
Properties
 
BP:
195.1°C at 760 mmHg  
Form:
Solid  
MP:
173-175 °C (lit.);  
Storage:
Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
52.8  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
7  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
2  

Downstream Synthesis Route
637-96-7    68-12-2   
C11H24N4(2+)*2ClO4(1-) 

[1]CollectionofCzechoslovakChemicalCommunications,1973,vol.38,p.2633-2640

64-17-5    637-96-7   
(Z)-3-Dimethylamino-2-(2-nitro-phenyl)-allylidene-dimethyl-ammonium;perchlorate 
  139984-67-1 

[1]BulletindelaSocieteChimiquedeFrance,1996,vol.133,p.251-266

[1]Chemistry-AEuropeanJournal,1998,vol.4,p.425-433

637-96-7    443361-05-5   
(3aRS,9bSR)-1,5-dimethyl-2,3,3a,4,5,9b-hexahydro-1H-pyrrolo3,2-cquinolin-4-one 
 
(3aRS,9bRS)-1,5-dimethyl-2,3,3a,4,5,9b-hexahydro-1H-pyrrolo3,2-cquinolin-4-one 

[1]TetrahedronLetters,2002,vol.43,p.1171-1174

637-96-7    443360-97-2   
<i>N</i>-(4-bromo-2-formyl-phenyl)-3-dimethylamino-propionamide 

[1]TetrahedronLetters,2002,vol.43,p.1171-1174

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Title: The glycine transport inhibitor sarcosine is an inhibitory glycine receptor agonist.

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Title: Inhibitors of GlyT1 affect glycine transport via discrete binding sites.

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Title: Differential effects of spinally applied glycine transporter inhibitors on nociception in a rat model of neuropathic pain.

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Title: Functional expression of the glycine transporter 1 on bullfrog retinal cones.

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Title: Mice with reduced NMDA receptor glycine affinity model some of the negative and cognitive symptoms of schizophrenia.

Journal: Psychopharmacology 20081001

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Title: Rescue of hippocampal LTP and learning deficits in a rat model of psychosis by inhibition of glycine transporter-1 (GlyT1).

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Title: The transglutaminase activating metalloprotease inhibitor from Streptomyces mobaraensis is a glutamine and lysine donor substrate of the intrinsic transglutaminase.

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Journal: Biochemical and biophysical research communications 20080808

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Title: Effect of poly(D, L-lactic acid) nanoparticles as triptolide carrier on abating rats renal toxicity by NMR-based metabolic analysis.

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Journal: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20080601

Title: Glycinergic nerve endings in hippocampus and spinal cord release glycine by different mechanisms in response to identical depolarizing stimuli.

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Title: Glycine transporter inhibitors as a potential therapeutic strategy for chronic pain with memory impairment.

Journal: Anesthesiology 20080501

Title: Betaine-homocysteine S-methyltransferase-2 is an S-methylmethionine-homocysteine methyltransferase.

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Title: Proteomic analysis of the sarcosine-insoluble outer membrane fraction of Flavobacterium columnare.

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Title: The potential for beta-structure in the repeat domain of tau protein determines aggregation, synaptic decay, neuronal loss, and coassembly with endogenous Tau in inducible mouse models of tauopathy.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20080116

Title: D-Serine and a glycine transporter inhibitor improve MK-801-induced cognitive deficits in a novel object recognition test in rats.

Journal: Behavioural brain research 20080110

Title: Sarcosine (N-methylglycine) treatment for acute schizophrenia: a randomized, double-blind study.

Journal: Biological psychiatry 20080101

Title: Development of an efficient protocol of RNA isolation from recalcitrant tree tissues.

Journal: Molecular biotechnology 20080101

Title: Near-infrared fluorescent labeled peptosome for application to cancer imaging.

Journal: Bioconjugate chemistry 20080101

Title: [Antinociceptive effects of glycine transporter inhibitors in neuropathic pain models in mice].

Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20071201

Title: The association of betaine, homocysteine and related metabolites with cognitive function in Dutch elderly people.

Journal: The British journal of nutrition 20071101

Title: Sex differences in the control of plasma concentrations and urinary excretion of glycine betaine in patients attending a lipid disorders clinic.

Journal: Clinical biochemistry 20071101

Title: The contribution of the NMDA receptor glycine site to rhythm generation during fictive swimming in Xenopus laevis tadpoles.

Journal: The European journal of neuroscience 20071101

Title: Structural and ligand-binding properties of serum albumin species interacting with a biomembrane interface.

Journal: Journal of pharmaceutical sciences 20071101

Title: Functional analysis of genes encoding putative oxidoreductases in Aspergillus oryzae, which are similar to fungal fructosyl-amino acid oxidase.

Journal: Journal of bioscience and bioengineering 20071101

Title: Can the interaction density be measured? The example of the non-standard amino acid sarcosine.

Journal: Acta crystallographica. Section A, Foundations of crystallography 20070901

Title: Pharmacological characterization of glycine-activated currents in HEK 293 cells expressing N-methyl-D-aspartate NR1 and NR3 subunits.

Journal: The Journal of pharmacology and experimental therapeutics 20070801

Title: DNA induces folding in alpha-synuclein: understanding the mechanism using chaperone property of osmolytes.

Journal: Archives of biochemistry and biophysics 20070801

Title: Light chain C-terminal region reinforces the stability of clathrin heavy chain trimers.

Journal: Traffic (Copenhagen, Denmark) 20070801

Title: A non-Q/N-rich prion domain of a foreign prion, [Het-s], can propagate as a prion in yeast.

Journal: Molecular cell 20070706

Title: Expedited, chemically enhanced sperm cell recovery from cotton swabs for rape kit analysis.

Journal: Journal of forensic sciences 20070701

Title: Kinetic studies on the role of Lys-171 and Lys-358 in the beta subunit of sarcosine oxidase from Corynebacterium sp. U-96.

Journal: Journal of biochemistry 20070601

Title: Glycine-induced long-term synaptic potentiation is mediated by the glycine transporter GLYT1.

Journal: Neuropharmacology 20070601

Title: YaeT-independent multimerization and outer membrane association of secretin PulD.

Journal: Molecular microbiology 20070601

Title: Synergistic effects of chemical enhancers on skin permeability: a case study of sodium lauroylsarcosinate and sorbitan monolaurate.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20070501

Title: Osmotic regulation of betaine homocysteine-S-methyltransferase expression in H4IIE rat hepatoma cells.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20070401

Title: High-affinity glycine and glutamate transport in pig forebrain white and gray matter: a quantitative study.

Journal: Neurochemistry international 20070401

Title: Natural approaches to epilepsy.

Journal: Alternative medicine review : a journal of clinical therapeutic 20070301

Title: Mixed osmolytes: the degree to which one osmolyte affects the protein stabilizing ability of another.

Journal: Protein science : a publication of the Protein Society 20070201

Title: Glycine- and sarcosine-based models of vanadate-dependent haloperoxidases in sulfoxygenation reactions.

Journal: Inorganic chemistry 20070108

Title: The organic osmolytes betaine and proline are transported by a shared system in early preimplantation mouse embryos.

Journal: Journal of cellular physiology 20070101

Title: Characterization of oxysterols by electrospray ionization tandem mass spectrometry after one-step derivatization with dimethylglycine.

Journal: Rapid communications in mass spectrometry : RCM 20070101

Title: Endogenous phospholipid metabolite containing topical product inhibits ultraviolet light-induced inflammation and DNA damage in human skin.

Journal: Skin pharmacology and physiology 20070101

Title: Immunomodulation of murine collagen-induced arthritis by N, N-dimethylglycine and a preparation of Perna canaliculus.

Journal: BMC complementary and alternative medicine 20070101

Title: Investigation of laser-microdissected inclusion bodies.

Journal: Methods in cell biology 20070101

Title: Application of the transfer model to understand how naturally occurring osmolytes affect protein stability.

Journal: Methods in enzymology 20070101

Title: Conformational behavior of N-acylamino acid oil and N-acylamino acid surfactant in aqueous solution.

Journal: Journal of oleo science 20070101

Title: Increasing the frequency of spontaneous rhythmic activity disrupts pool-specific axon fasciculation and pathfinding of embryonic spinal motoneurons.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20061206

Title: Effects of substrate and potassium on the betaine-synthesizing enzyme glycine sarcosine dimethylglycine N-methyltransferase from a halophilic methanoarchaeon Methanohalophilus portucalensis.

Journal: Research in microbiology 20061201

Title: Systematic identification of the subproteome of Escherichia coli cell envelope reveals the interaction network of membrane proteins and membrane-associated peripheral proteins.

Journal: Journal of proteome research 20061201

Title: Glycine transporter I inhibitor, N-methylglycine (sarcosine), added to clozapine for the treatment of schizophrenia.

Journal: Biological psychiatry 20060915

Title: Tektin interactions and a model for molecular functions.

Journal: Experimental cell research 20060910

Title: New 64Cu PET imaging agents for personalised medicine and drug development using the hexa-aza cage, SarAr.

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Title: Pharmacological properties of glycine uptake in the developing rat retina.

Journal: Neurochemistry international 20060901

Title: Designing amino acid residues with single-conformations.

Journal: Protein engineering, design & selection : PEDS 20060901

Title: Effect of ethylene glycol, urea, and N-methylated glycines on DNA thermal stability: the role of DNA base pair composition and hydration.

Journal: Biochemistry 20060808

Title: Inhibition of the glycine transporter GlyT-1 potentiates the effect of risperidone, but not clozapine, on glutamatergic transmission in the rat medial prefrontal cortex.

Journal: Synapse (New York, N.Y.) 20060801

Title: A report of two families with sarcosinaemia in Hong Kong and revisiting the pathogenetic potential of hypersarcosinaemia.

Journal: Annals of the Academy of Medicine, Singapore 20060801

Title: Heterotetrameric sarcosine oxidase: structure of a diflavin metalloenzyme at 1.85 A resolution.

Journal: Journal of molecular biology 20060728

Title: Mild and nonracemizing conditions for Ullmann-type diaryl ether formation between aryl iodides and tyrosine derivatives.

Journal: The Journal of organic chemistry 20060707

Title: Critical factors influencing prion inactivation by sodium hydroxide.

Journal: Vox sanguinis 20060701

Title: Degradation of glyphosate in soil and its effect on fungal population.

Journal: Journal of environmental science & engineering 20060701

Title: Design and synthesis of novel sulfonamide-containing bradykinin hB2 receptor antagonists. 1. Synthesis and SAR of alpha,alpha-dimethylglycine sulfonamides.

Journal: Journal of medicinal chemistry 20060615

Title: Transactivation of rat apical sodium-dependent bile acid transporter and increased bile acid transport by 1alpha,25-dihydroxyvitamin D3 via the vitamin D receptor.

Journal: Molecular pharmacology 20060601

Title: Use of sodium lauroyl sarcosinate in a high-sensitivity protein assay by resonance light scattering technique.

Journal: Journal of biomolecular screening 20060601

Title: Modulatory effects of d-serine and sarcosine on NMDA receptor-mediated neurotransmission are apparent after stress in the genetically inbred BALB/c mouse strain.

Journal: Brain research bulletin 20060531

Title: Functionalisation of carbon nanohorns.

Journal: Chemical communications (Cambridge, England) 20060528

Title: GABAergic and glycinergic inhibitory mechanisms in the lamprey respiratory control.

Journal: Brain research 20060523

Title: The paradoxical thermodynamic basis for the interaction of ethylene glycol, glycine, and sarcosine chains with bovine carbonic anhydrase II: an unexpected manifestation of enthalpy/entropy compensation.

Journal: Journal of the American Chemical Society 20060503

Title: Liquid-crystalline fullerodendrimers which display columnar phases.

Journal: Organic letters 20060427

Title: Sensitivity to detergents and plasmid curing in Enterococcus faecalis.

Journal: Journal of industrial microbiology & biotechnology 20060301

Title: Sarcosine based indandione hGlyT1 inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20060301

Title: Is the glycine site half saturated or half unsaturated? Effects of glutamatergic drugs in schizophrenia patients.

Journal: Current opinion in psychiatry 20060301

Title: Application of electron spin resonance spin-trapping technique for evaluation of substrates and inhibitors of nitric oxide synthase.

Journal: Analytical biochemistry 20060201

Title: Analysis of the Pasteurella multocida outer membrane sub-proteome and its response to the in vivo environment of the natural host.

Journal: Proteomics 20060201

Title: Glutamate-based therapeutic approaches: inhibitors of glycine transport.

Journal: Current opinion in pharmacology 20060201

Title: Treatment for mitochondrial disorders.

Journal: The Cochrane database of systematic reviews 20060125

Title: Purification and antigenicity of two recombinant forms of Boophilus microplus yolk pro-cathepsin expressed in inclusion bodies.

Journal: Protein expression and purification 20060101

Title: Development of a novel high-throughput assay for the investigation of GlyT-1b neurotransmitter transporter function.

Journal: Combinatorial chemistry & high throughput screening 20060101

Title: Progress towards validating the NMDA receptor hypofunction hypothesis of schizophrenia.

Journal: Current topics in medicinal chemistry 20060101

Title: Progress in the preparation and testing of glycine transporter type-1 (GlyT1) inhibitors.

Journal: Current topics in medicinal chemistry 20060101

Title: Rare neurodevelopmental abnormalities of sarcosinemia may involve glycinergic stimulation of a primed N-methyl-d-aspartate receptor.

Journal: Clinical neuropharmacology 20060101

Title: Ionization of zwitterionic amine substrates bound to monomeric sarcosine oxidase.

Journal: Biochemistry 20051227

Title: Electron propagator theory study of N-/O-methylglycine conformers.

Journal: The Journal of chemical physics 20051222

Title: Redox cycling of iron complexes of N-(dithiocarboxy)sarcosine and N-methyl-D-glucamine dithiocarbamate.

Journal: Free radical biology & medicine 20051215

Title: Synergistic fungicidal activity of Cu(2+) and allicin, an allyl sulfur compound from garlic, and its relation to the role of alkyl hydroperoxide reductase 1 as a cell surface defense in Saccharomyces cerevisiae.

Journal: Toxicology 20051115

Title: Poly(N-acryloylsarcosine methyl ester) protein-resistant surfaces.

Journal: The journal of physical chemistry. B 20051110

Title: Transmembrane domains 1 and 3 of the glycine transporter GLYT1 contain structural determinants of N[3-(4'-fluorophenyl)-3-(4'-phenylphenoxy)-propyl]sarcosine specificity.

Journal: Neuropharmacology 20051101

Title: Mixed complexes of Pt(II) and Pd(II) with ethylsarcosinedithiocarbamate and 2-/3-picoline as antitumor agents.

Journal: Journal of inorganic biochemistry 20051101

Title: Sarcosine or D-serine add-on treatment for acute exacerbation of schizophrenia: a randomized, double-blind, placebo-controlled study.

Journal: Archives of general psychiatry 20051101

Title: Reactivities of quinone-free DsbB from Escherichia coli.

Journal: The Journal of biological chemistry 20050923

Title: Sexual dimorphism in urinary metabolite profiles of Han Wistar rats revealed by nuclear-magnetic-resonance-based metabonomics.

Journal: Analytical biochemistry 20050815

Title: Gas-phase structure of N,N-dimethylglycine.

Journal: Chemphyschem : a European journal of chemical physics and physical chemistry 20050812

Title: Inhibitors of GlyT1 and GlyT2 differentially modulate inhibitory transmission.

Journal: Neuroreport 20050801

Title: Crystal structure of heterotetrameric sarcosine oxidase from Corynebacterium sp. U-96.

Journal: Biochemical and biophysical research communications 20050729

Title: The zebrafish shocked gene encodes a glycine transporter and is essential for the function of early neural circuits in the CNS.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20050713

Title: Bile acid induces hydrophobicity-dependent membrane alterations.

Journal: Biochimica et biophysica acta 20050615

Title: Comprehensive assignment of mass spectral signatures from individual Bacillus atrophaeus spores in matrix-free laser desorption/ionization bioaerosol mass spectrometry.

Journal: Analytical chemistry 20050515

Title: Ampicillin/penicillin-binding protein interactions as a model drug-target system to optimize affinity pull-down and mass spectrometric strategies for target and pathway identification.

Journal: Proteomics 20050501

Title: Corynebacterium sp. U-96 contains a cluster of genes of enzymes for the catabolism of sarcosine to pyruvate.

Journal: Bioscience, biotechnology, and biochemistry 20050501

Title: Modulation of striatal dopamine release by glycine transport inhibitors.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20050401

Title: Synthesis, characterization, and comparative in vitro cytotoxicity studies of platinum(II), palladium(II), and gold(III) methylsarcosinedithiocarbamate complexes.

Journal: Journal of medicinal chemistry 20050310

Title: Inhibition of system A-mediated glycine transport in cortical synaptosomes by therapeutic concentrations of clozapine: implications for mechanisms of action.

Journal: Molecular psychiatry 20050301

Title: pH and kinetic isotope effects on sarcosine oxidation by N-methyltryptophan oxidase.

Journal: Biochemistry 20050301

Title: Statistical total correlation spectroscopy: an exploratory approach for latent biomarker identification from metabolic 1H NMR data sets.

Journal: Analytical chemistry 20050301

Title: High-throughput solution-based medicinal library screening against human serum albumin.

Journal: Analytical chemistry 20050301

Title: Occupational allergic contact dermatitis to sodium lauroyl sarcosinate in the liquid soap.

Journal: Contact dermatitis 20050301

Title: Characterization of strychnine-sensitive glycine receptor in the intact frog retina: modulation by protein kinases.

Journal: Neurochemical research 20050301

Title: Betaine and folate status as cooperative determinants of plasma homocysteine in humans.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20050201

Title: Efficient release from promoter-proximal stall sites requires transcript cleavage factor TFIIS.

Journal: Molecular cell 20050107

Title: Homocysteine, glycine betaine, and N,N-dimethylglycine in patients attending a lipid clinic.

Journal: Metabolism: clinical and experimental 20050101

Title: 3H-L-histidine and 65Zn(2+) are cotransported by a dipeptide transport system in intestine of lobster Homarus americanus.

Journal: The Journal of experimental biology 20050101

Title: Enteric-coated cholylsarcosine microgranules for the treatment of short bowel syndrome.

Journal: The Journal of pharmacy and pharmacology 20050101

Title: hPEPT1 affinity and translocation of selected Gln-Sar and Glu-Sar dipeptide derivatives.

Journal: Molecular pharmaceutics 20050101

Title: Force measurement for antigen-antibody interaction by atomic force microscopy using a photograft-polymer spacer.

Journal: Biomacromolecules 20050101

Title: Proteomic analysis of the sarcosine-insoluble outer membrane fraction of Pseudomonas aeruginosa responding to ampicilin, kanamycin, and tetracycline resistance.

Journal: Journal of proteome research 20050101

Title: Dimethylglycine supplementation does not affect plasma homocysteine concentrations in pre-dialysis chronic renal failure patients.

Journal: Clinical biochemistry 20041101

Title: Effects of intravenous betaine on methionine-loading-induced plasma homocysteine elevation in rats.

Journal: The Journal of nutritional biochemistry 20041101

Title: An isatin-beta-thiosemicarbazone-resistant vaccinia virus containing a mutation in the second largest subunit of the viral RNA polymerase is defective in transcription elongation.

Journal: The Journal of biological chemistry 20041022

Title: Blockade of glycine transporter-1 (GLYT-1) potentiates NMDA receptor-mediated synaptic transmission in hypoglossal motorneurons.

Journal: Journal of neurophysiology 20041001

Title: Over-expression in Escherichia coli, functional characterization and refolding of rat dimethylglycine dehydrogenase.

Journal: Protein expression and purification 20041001

Title: Proteomic analysis of the sarcosine-insoluble outer membrane fraction of the bacterial pathogen Bartonella henselae.

Journal: Proteomics 20041001

Title: Spinnokinetic analyses of blood disposition and biliary excretion of nitric oxide (NO)-Fe(II)-N-(dithiocarboxy)sarcosine complex in rats: BCM-ESR and BEM-ESR studies.

Journal: Free radical research 20041001

Title: Osmolytes induce structure in an early intermediate on the folding pathway of barstar.

Journal: The Journal of biological chemistry 20040924

Title: Iodo-controlled selective formation of pyrrolidino[60]fullerene and aziridino[60]fullerene from the reaction between C6) and amino acid esters.

Journal: The Journal of organic chemistry 20040820

Title: Phosphorylated p38MAPK specific antibodies cross-react with sarkosyl-insoluble hyperphosphorylated tau proteins.

Journal: Journal of neurochemistry 20040801

Title: Study in vitro and in vivo of nociceptin/orphanin FQ(1-13)NH2 analogues substituting N-Me-Gly for Gly2 or Gly3.

Journal: Peptides 20040801

Title: Annular alpha-synuclein species from purified multiple system atrophy inclusions.

Journal: Journal of neurochemistry 20040701

Title: Conjugated bile acid replacement therapy in short bowel syndrome patients with a residual colon.

Journal: Zeitschrift fur Gastroenterologie 20040701

Title: Interactions of enzymes and a lectin with a chitin-based graft copolymer having polysarcosine side chains.

Journal: Macromolecular bioscience 20040625

Title: Glycine transporter type 1 blockade changes NMDA receptor-mediated responses and LTP in hippocampal CA1 pyramidal cells by altering extracellular glycine levels.

Journal: The Journal of physiology 20040601

Title: Mutational and structural-based analyses of the osmolyte effect on protein stability.

Journal: Journal of biochemistry 20040601

Title: Dissecting the catalytic mechanism of betaine-homocysteine S-methyltransferase by use of intrinsic tryptophan fluorescence and site-directed mutagenesis.

Journal: Biochemistry 20040511

Title: Characterization and metabolic function of a peroxisomal sarcosine and pipecolate oxidase from Arabidopsis.

Journal: The Journal of biological chemistry 20040423

Title: The interaction of human serum albumin with a novel antidiabetic agent--SU-118.

Journal: Journal of pharmaceutical sciences 20040401

Title: Glycine transporter I inhibitor, N-methylglycine (sarcosine), added to antipsychotics for the treatment of schizophrenia.

Journal: Biological psychiatry 20040301

Title: Influence of hemodialysis membrane permeability on serum levels of advanced glycation end products (AGEs) and homocysteine metabolites.

Journal: Clinical nephrology 20040301

Title: Immune response induced by N-lauroylsarcosine extracted outer-membrane proteins of an isolate of Edwardsiella ictaluri in channel catfish.

Journal: Fish & shellfish immunology 20040301

Title: Reversal of phencyclidine-induced dopaminergic dysregulation by N-methyl-D-aspartate receptor/glycine-site agonists.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20040201

Title: Betaine as a determinant of postmethionine load total plasma homocysteine before and after B-vitamin supplementation.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20040201

Title: Pharmacological properties of glycine transport in the frog retina.

Journal: Neurochemical research 20040101

Title: Epidemiological and serological survey of brucellosis in Mongolia by ELISA using sarcosine extracts.

Journal: Microbiology and immunology 20040101

Title: A strategy for identification and quantification of detergents frequently used in the purification of membrane proteins.

Journal: Analytical biochemistry 20031215

Title: A new class of potent vascular endothelial growth factor receptor tyrosine kinase inhibitors: structure-activity relationships for a series of 9-alkoxymethyl-12-(3-hydroxypropyl)indeno[2,1-a]pyrrolo[3,4-c]carbazole-5-ones and the identification of CEP-5214 and its dimethylglycine ester prodrug clinical candidate CEP-7055.

Journal: Journal of medicinal chemistry 20031204

Title: Inactivation of the glycine transporter 1 gene discloses vital role of glial glycine uptake in glycinergic inhibition.

Journal: Neuron 20031113

Title: Exploration of the P6/P7 region of the peptide-binding site of the human class II major histocompatability complex protein HLA-DR1.

Journal: The Journal of biological chemistry 20031107

Title: Effects of endogenous agonists, glycine and D-serine, on in vivo specific binding of [11C]L-703,717, a PET radioligand for the glycine-binding site of NMDA receptors.

Journal: Synapse (New York, N.Y.) 20031101

Title: In vivo characterization of changes in glycine levels induced by GlyT1 inhibitors.

Journal: Annals of the New York Academy of Sciences 20031101

Title: Aberrant Cdk5 activation by p25 triggers pathological events leading to neurodegeneration and neurofibrillary tangles.

Journal: Neuron 20031030

Title: N,N-dimethyl glycine-promoted Ullmann coupling reaction of phenols and aryl halides.

Journal: Organic letters 20031016

Title: Pharmacology and expression analysis of glycine transporter GlyT1 with [3H]-(N-[3-(4'-fluorophenyl)-3-(4'phenylphenoxy)propyl])sarcosine.

Journal: Neuropharmacology 20031001

Title: Persistence of adhesive properties in Vibrio cholerae after long-term exposure to sea water.

Journal: Environmental microbiology 20031001

Title: Synthesis of phosphorothioate oligonucleotides with stereodefined phosphorothioate linkages.

Journal: Current protocols in nucleic acid chemistry 20031001

Title: Quantitative recovery of immunoreactive proteins from clinical samples following RNA and DNA isolation.

Journal: BioTechniques 20030901

Title: The glycine transporter type 1 inhibitor N-[3-(4'-fluorophenyl)-3-(4'-phenylphenoxy)propyl]sarcosine potentiates NMDA receptor-mediated responses in vivo and produces an antipsychotic profile in rodent behavior.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20030820

Title: Enzyme-linked immunosorbent assay to differentiate the antibody responses of animals infected with Brucella species from those of animals infected with Yersinia enterocolitica O9.

Journal: Clinical and diagnostic laboratory immunology 20030701

Title: Sarcosine-maleic acid (1:1) crystal: structure, 13C NMR and vibrational properties, protonation character.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20030601

Title: Optimized conventional synthesis of 'RGD' and 'RGDS' peptides and their sarcosine mimics as integrin GP IIb/IIIa antagonists.

Journal: Amino acids 20030601

Title: Degradation, cyclic adenosine monophosphate production, insulin secretion, and glycemic effects of two novel N-terminal Ala2-substituted analogs of glucose-dependent insulinotropic polypeptide with preserved biological activity in vivo.

Journal: Metabolism: clinical and experimental 20030601

Title: [3H]-(R)-NPTS, a radioligand for the type 1 glycine transporter.

Journal: Bioorganic & medicinal chemistry letters 20030407

Title: Kinetic mechanisms of glycine oxidase from Bacillus subtilis.

Journal: European journal of biochemistry 20030401

Title: Role of EphA4 and EphrinB3 in local neuronal circuits that control walking.

Journal: Science (New York, N.Y.) 20030321

Title: Oral bile acids reduce bacterial overgrowth, bacterial translocation, and endotoxemia in cirrhotic rats.

Journal: Hepatology (Baltimore, Md.) 20030301

Title: The glycine transporter-1 inhibitors NFPS and Org 24461: a pharmacological study.

Journal: Pharmacology, biochemistry, and behavior 20030301

Title: Molecular recognition in the gas phase ligand switching reactions of the proton bound dimer of sarcosine and glycylglycine.

Journal: Organic & biomolecular chemistry 20030221

Title: A hydrophobicity scale for the lipid bilayer barrier domain from peptide permeabilities: nonadditivities in residue contributions.

Journal: Biochemistry 20030218

Title: Determination of choline, betaine, and dimethylglycine in plasma by a high-throughput method based on normal-phase chromatography-tandem mass spectrometry.

Journal: Clinical chemistry 20030201

Title: Glycine tranporter-1 blockade potentiates NMDA-mediated responses in rat prefrontal cortical neurons in vitro and in vivo.

Journal: Journal of neurophysiology 20030201

Title: Pt(II) and Pd(II) derivatives of ter-butylsarcosinedithiocarbamate. Synthesis, chemical and biological characterization and in vitro nephrotoxicity.

Journal: Journal of inorganic biochemistry 20030115

Title: Conjugated bile acid replacement therapy reduces urinary oxalate excretion in short bowel syndrome.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20030101

Title: The effect of short-term dimethylglycine treatment on oxygen consumption in cytochrome oxidase deficiency: a double-blind randomized crossover clinical trial.

Journal: The Journal of pediatrics 20030101

Title: Pharmacokinetics of oral betaine in healthy subjects and patients with homocystinuria.

Journal: British journal of clinical pharmacology 20030101

Title: Isolation of cosmid and BAC DNA from E. coli.

Journal: Methods in molecular biology (Clifton, N.J.) 20030101

Title: Assembly of tau in transgenic animals expressing P301L tau: alteration of phosphorylation and solubility.

Journal: Journal of neurochemistry 20021201

Title: Abundant tau filaments and nonapoptotic neurodegeneration in transgenic mice expressing human P301S tau protein.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20021101

Title: Glycine receptors and transporters on bullfrog retinal Müller cells.

Journal: Neuroreport 20020916

Title: Promoter escape by RNA polymerase II.

Journal: Biochimica et biophysica acta 20020913

Title: Iron (III) induces aggregation of hyperphosphorylated tau and its reduction to iron (II) reverses the aggregation: implications in the formation of neurofibrillary tangles of Alzheimer's disease.

Journal: Journal of neurochemistry 20020901

Title: Synthesis, characterization and in vitro cytotoxicity of new organotin(IV) derivatives of N-methylglycine.

Journal: Journal of inorganic biochemistry 20020815

Title: Assay of the concentration and (13)C isotopic enrichment of propionyl-CoA, methylmalonyl-CoA, and succinyl-CoA by gas chromatography-mass spectrometry.

Journal: Analytical biochemistry 20020601

Title: Peptoid residues and beta-turn formation.

Journal: Journal of peptide science : an official publication of the European Peptide Society 20020601

Title: Mechanistic aspects of the covalent flavoprotein dimethylglycine oxidase of Arthrobacter globiformis studied by stopped-flow spectrophotometry.

Journal: Biochemistry 20020409

Title: An unexpected Diels-Alder reaction on the fullerene core rather than an expected 1,3-dipolar cycloaddition.

Journal: Chemical communications (Cambridge, England) 20020407

Title: Late-onset frontotemporal dementia with a novel exon 1 (Arg5His) tau gene mutation.

Journal: Annals of neurology 20020401

Title: Detergent extract from chlamydial elementary bodies used as antigen for enzyme-linked immunosorbent assay.

Journal: Diagnostic microbiology and infectious disease 20020401

Title: Placental ceruloplasmin homolog is regulated by iron and copper and is implicated in iron metabolism.

Journal: American journal of physiology. Cell physiology 20020301

Title: Betaine supplementation decreases post-methionine hyperhomocysteinemia in chronic renal failure.

Journal: Kidney international 20020301

Title: Single crystal EPR studies on Mn(II)-doped sarcosine cadmium chloride and sarcosine cadmium bromide: study of zero-field splitting tensor in iso-structural complexes.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20020201

Title: Lysosomotropic N,N- dimethyl alpha-aminoacid N-alkyl esters and their quaternary ammonium salts as plasma membrane and mitochondrial ATPases inhibitors.

Journal: Cellular & molecular biology letters 20020101

Title: The Gd(3+) complex of a fatty acid analogue of DOTP binds to multiple albumin sites with variable water relaxivities.

Journal: Inorganic chemistry 20011217

Title: Ultrastructural and biochemical localization of N-RAP at the interface between myofibrils and intercalated disks in the mouse heart.

Journal: Biochemistry 20011211

Title: ALX 5407: a potent, selective inhibitor of the hGlyT1 glycine transporter.

Journal: Molecular pharmacology 20011201

Title: N[3-(4'-fluorophenyl)-3-(4'-phenylphenoxy)propyl]sarcosine (NFPS) is a selective persistent inhibitor of glycine transport.

Journal: British journal of pharmacology 20011201

Title: B-subunit of phosphate-specific transporter from Mycobacterium tuberculosis is a thermostable ATPase.

Journal: The Journal of biological chemistry 20011130

Title: Decrease of elevated N,N-dimethylglycine and N-methylglycine in human immunodeficiency virus infection during short-term highly active antiretroviral therapy.

Journal: Metabolism: clinical and experimental 20011101

Title: Conformational change, aggregation and fibril formation induced by detergent treatments of cellular prion protein.

Journal: Journal of neurochemistry 20011101

Title: Osmolytes as modulators of conformational changes in serpins.

Journal: Biological chemistry 20011101

Title: Synthesis and spectroscopic characterization of protected N-phosphonomethylglycine dipeptides.

Journal: Journal of peptide science : an official publication of the European Peptide Society 20010901

Title: Investigations into biochemical changes due to diurnal variation and estrus cycle in female rats using high-resolution (1)H NMR spectroscopy of urine and pattern recognition.

Journal: Analytical biochemistry 20010815

Title: Osmolytes stabilize ribonuclease S by stabilizing its fragments S protein and S peptide to compact folding-competent states.

Journal: The Journal of biological chemistry 20010803

Title: Purification and kinetic properties of betaine-homocysteine methyltransferase from Aphanothece halophytica.

Journal: Current microbiology 20010801

Title: Intracellular re-routing of prion protein prevents propagation of PrP(Sc) and delays onset of prion disease.

Journal: The EMBO journal 20010801

Title: Glycine N-methyltransferase deficiency: a novel inborn error causing persistent isolated hypermethioninaemia.

Journal: Journal of inherited metabolic disease 20010801

Title: Homocysteine metabolism in children with Down syndrome: in vitro modulation.

Journal: American journal of human genetics 20010701

Title: Pharmacological assessment of the role of the glycine transporter GlyT-1 in mediating high-affinity glycine uptake by rat cerebral cortex and cerebellum synaptosomes.

Journal: Neuropharmacology 20010701

Title: Dimethylglycine accumulates in uremia and predicts elevated plasma homocysteine concentrations.

Journal: Kidney international 20010601

Title: Organization of the genes involved in dimethylglycine and sarcosine degradation in Arthrobacter spp.: implications for glycine betaine catabolism.

Journal: European journal of biochemistry 20010601

Title: Cloning of dimethylglycine dehydrogenase and a new human inborn error of metabolism, dimethylglycine dehydrogenase deficiency.

Journal: American journal of human genetics 20010401

Title: Conformation of cationic N,N-dimethylglycine in dimethylglycinium trifluoroacetate.

Journal: Acta crystallographica. Section C, Crystal structure communications 20010401

Title: Effectiveness of N,N-dimethylglycine in autism and pervasive developmental disorder.

Journal: Journal of child neurology 20010301

Title: Co-localization of alpha-synuclein and phosphorylated tau in neuronal and glial cytoplasmic inclusions in a patient with multiple system atrophy of long duration.

Journal: Acta neuropathologica 20010301

Title: Analysis of alcohols, as dimethylglycine esters, by electrospray ionization tandem mass spectrometry.

Journal: Journal of mass spectrometry : JMS 20010301

Title: N-methyltryptophan oxidase from Escherichia coli: reaction kinetics with N-methyl amino acid and carbinolamine substrates.

Journal: Biochemistry 20010206

Title: Distinct isoforms of tau aggregated in neurons and glial cells in brains of patients with Pick's disease, corticobasal degeneration and progressive supranuclear palsy.

Journal: Acta neuropathologica 20010201

Title: ICE bioassay. Isolating in vivo complexes of enzyme to DNA.

Journal: Methods in molecular biology (Clifton, N.J.) 20010101

Title: Raman spectroscopy in magnetic fluids.

Journal: Biomolecular engineering 20010101

Title: Final report on the safety assessment of Cocoyl Sarcosine, Lauroyl Sarcosine, Myristoyl Sarcosine, Oleoyl Sarcosine, Stearoyl Sarcosine, Sodium Cocoyl Sarcosinate, Sodium Lauroyl Sarcosinate, Sodium Myristoyl Sarcosinate, Ammonium Cocoyl Sarcosinate, and Ammonium Lauroyl Sarcosinate.

Journal: International journal of toxicology 20010101

Title: L-Pipecolic acid oxidase, a human enzyme essential for the degradation of L-pipecolic acid, is most similar to the monomeric sarcosine oxidases.

Journal: The Biochemical journal 20000201

Title: Dual effects of lisinopril on puromycin aminonucleoside nephrosis in unilaterally nephrectomized rats.

Journal: Japanese journal of pharmacology 19970401

Title: Cloning and functional expression of a mammalian gene for a peroxisomal sarcosine oxidase.

Journal: The Journal of biological chemistry 19970307

Title: NMR and X-ray crystallographic studies on cyclic tetrapeptide, cyclo (D-Phe-Pro-Sar-Gly).

Journal: International journal of peptide and protein research 19960701

Title: Betaine:homocysteine methyltransferase from rat liver: purification and inhibition by a boronic acid substrate analog.

Journal: Archives of biochemistry and biophysics 19920101

Title: Effects of cellular copper content on copper uptake and metallothionein and ceruloplasmin mRNA levels in mouse hepatocytes.

Journal: The Journal of nutrition 19901101

Title: Demonstration of human, rye grass pollen extract-specific, helper and suppressor stimulating activity of modified allergens by effects on in vitro hapten-specific antibody production.

Journal: International archives of allergy and applied immunology 19890101

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Tags:637-96-7 Molecular Formula|637-96-7 MDL|637-96-7 SMILES|637-96-7 Sarcosine hydrochloride |Organic_Building_Blocks