Home Indole and Oxindoles 65347-55-9
65347-55-9,MFCD03695471
Catalog No.:AA00EB9S

65347-55-9 | 3-(1,2,3,6-Tetrahydropyridin-4-yl)-1h-indole

Pack Size
Purity
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Price(USD)
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250mg
95%
in stock  
$80.00   $56.00
- +
1g
95%
in stock  
$199.00   $139.00
- +
5g
95%
in stock  
$786.00   $550.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00EB9S
Chemical Name:
3-(1,2,3,6-Tetrahydropyridin-4-yl)-1h-indole
CAS Number:
65347-55-9
Molecular Formula:
C13H14N2
Molecular Weight:
198.2637
MDL Number:
MFCD03695471
SMILES:
N1CCC(=CC1)c1c[nH]c2c1cccc2
Properties
Computed Properties
 
Complexity:
259  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
15  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
1  
XLogP3:
1.8  

Downstream Synthesis Route

[1]Guillaume;Dumont;Laurent;Nedelec[EuropeanJournalofMedicinalChemistry,1987,vol.22,#1,p.33-43]

[2]CurrentPatentAssignee:SANOFI-US4278677,1981,A

[1]Fonquerna,Silvia;Miralpeix,Montse;Pagès,Lluís;Puig,Carles;Cardús,Arantxa;Antón,Francisca;Cárdenas,Álvaro;Vilella,Dolors;Aparici,Mónica;Calaf,Elena;Prieto,José;Gras,Jordi;Huerta,JosepM.;Warrellow,Graham;Beleta,Jorge;Ryder,Hamish[JournalofMedicinalChemistry,2004,vol.47,#25,p.6326-6337]

[2]CurrentPatentAssignee:MERCEDES-BENZGROUPAG;FCA(in:Stellantis);STELLANTISNV-WO2004/43949,2004,A1Locationinpatent:Page/Pagecolumn30

[3]CurrentPatentAssignee:ALMIRALLSA-US2002/147344,2002,A1

[4]CurrentPatentAssignee:ALMIRALLSA-US2004/116471,2004,A1

[5]CurrentPatentAssignee:ALMIRALLSA-WO2003/99807,2003,A1Locationinpatent:Page9

[6]Freter;Fuchs;Barsumian;Oliver[Arzneimittel-Forschung/DrugResearch,1985,vol.35,#1A,p.272-276]

[7]CurrentPatentAssignee:CHINESEACADEMYOFSCIENCES;HARVARDUNIVERSITY-WO2011/143444,2011,A2Locationinpatent:Page/Pagecolumn7;87-90

[8]CurrentPatentAssignee:MERCK&COINC;UNIVERSITYOFDUNDEE-WO2015/82499,2015,A2Locationinpatent:Page/Pagecolumn142-143

[1]Patent:US2002/187983,2002,A1

[2]Patent:US5936089,1999,A

120-72-9    40064-34-4   
potassiumchloride 
  65347-55-9 

[1]Patent:US2002/147344,2002,A1

[2]Patent:US2004/116471,2004,A1

[1]Patent:US4324790,1982,A

Literature

Title: Essential role for orbitofrontal serotonin 1B receptors in obsessive-compulsive disorder-like behavior and serotonin reuptake inhibitor response in mice.

Journal: Biological psychiatry 20111201

Title: Novel 4-aryl-pyrido[1,2-c]pyrimidines with dual SSRI and 5-HT(1A) activity. part 3.

Journal: European journal of medicinal chemistry 20110101

Title: Chronic reductions in serotonin transporter function prevent 5-HT1B-induced behavioral effects in mice.

Journal: Biological psychiatry 20090301

Title: Pharmacological alterations of anxious behaviour in mice depending on both strain and the behavioural situation.

Journal: PloS one 20090101

Title: Anticonvulsant effect of the selective 5-HT1B receptor agonist CP 94253 in mice.

Journal: European journal of pharmacology 20060710

Title: Postsynaptic 5-HT1B receptors modulate electroshock-induced generalised seizures in rats.

Journal: British journal of pharmacology 20050301

Title: Stimulation of 5-HT1B receptors decreases cocaine- and sucrose-seeking behavior.

Journal: Pharmacology, biochemistry, and behavior 20050201

Title: Discriminative stimulus effects of ethanol in rats using a three-choice ethanol-midazolam-water discrimination.

Journal: Behavioural pharmacology 20041201

Title: Enkephalin contributes to the locomotor stimulating effects of 3,4-methylenedioxy-N-methylamphetamine.

Journal: The European journal of neuroscience 20030701

Title: SLV310, a novel, potential antipsychotic, combining potent dopamine D2 receptor antagonism with serotonin reuptake inhibition.

Journal: Bioorganic & medicinal chemistry letters 20030210

Title: Subthalamic 5-HT(1A) and 5-HT(1B) receptor modulation of RU 24969-induced behavioral profile in rats.

Journal: Pharmacology, biochemistry, and behavior 20020401

Title: Serotonin 2C receptor agonists and the behavioural satiety sequence in mice.

Journal: Pharmacology, biochemistry, and behavior 20020401

Title: An investigation of the role of 5-HT(2C) receptors in modifying ethanol self-administration behaviour.

Journal: Pharmacology, biochemistry, and behavior 20020401

Title: Serotonin-1B receptor-mediated inhibition of [(3)H]GABA release from rat ventral tegmental area slices.

Journal: Journal of neurochemistry 20011101

Title: Role of 5-HT(1A) and 5-HT(1B) receptors in the mediation of behavior in the forced swim test in mice.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20010401

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Tags:65347-55-9 Molecular Formula|65347-55-9 MDL|65347-55-9 SMILES|65347-55-9 3-(1,2,3,6-Tetrahydropyridin-4-yl)-1h-indole