Home Amines 660-88-8
660-88-8,MFCD01570290
Catalog No.:AA0038H1

660-88-8 | 5-Aminovaleric acid

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1g
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$7.00   $5.00
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5g
97%
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$19.00   $13.00
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10g
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$20.00   $14.00
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25g
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  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA0038H1
Chemical Name:
5-Aminovaleric acid
CAS Number:
660-88-8
Molecular Formula:
C5H11NO2
Molecular Weight:
117.1463
MDL Number:
MFCD01570290
SMILES:
NCCCCC(=O)O
Properties
Computed Properties
 
Complexity:
72.8  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
8  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
4  
XLogP3:
-2.6  

Upstream Synthesis Route

[1]Synthesis,2008,#8,p.1316-1318

[2]BioorganicandMedicinalChemistryLetters,2008,vol.18,#22,p.5926-5931

[3]Tetrahedron,2012,vol.68,#16,p.3336-3341

[1]OrganicandBiomolecularChemistry,2014,vol.12,#34,p.6624-6633

[1]OrganicandBiomolecularChemistry,2014,vol.12,#34,p.6624-6633

[1]JournaloftheAmericanChemicalSociety,2018,vol.140,#44,p.14599-14603

[2]ChemMedChem,2016,p.1172-1187

[3]ChemMedChem,2016,vol.11,#11,p.1172-1187

[4]ACSMedicinalChemistryLetters,2013,vol.4,#4,p.402-407

[5]Patent:US4476228,1984,A,

[6]Patent:US4476229,1984,A,

[7]Patent:WO2012/143703,2012,A1,.Locationinpatent:Page/Pagecolumn37

[8]CarbohydrateResearch,2010,vol.345,#1,p.33-40

[9]Tetrahedron,2005,vol.61,#24,p.5906-5914

[10]TetrahedronLetters,2007,vol.48,#39,p.6996-6999

[11]Synthesis,1988,#3,p.259-261

[12]BioorganicandMedicinalChemistry,2014,vol.22,#16,p.4499-4505

[13]JournalofMedicinalChemistry,2017,vol.60,#12,p.4840-4860

[14]BioorganicandMedicinalChemistryLetters,2005,vol.15,#8,p.1969-1972

[15]JournalofMedicinalChemistry,2001,vol.44,#4,p.548-565

[16]Patent:US4722810,1988,A,

[17]BulletinoftheChemicalSocietyofJapan,2010,vol.83,#5,p.546-553

[18]RussianJournalofGeneralChemistry,2010,vol.80,#12,p.2572-2589

[19]Patent:US2011/281893,2011,A1,.Locationinpatent:Page/Pagecolumn13-14

[20]ZeitschriftfurNaturforschung-SectionBJournalofChemicalSciences,2012,vol.67,#7,p.731-746

[21]ArchivderPharmazie,2014,vol.347,#2,p.77-88

[22]JournalofMedicinalChemistry,2017,vol.60,#4,p.1605-1610

[1]Patent:US2004/235712,2004,A1,.Locationinpatent:Page/Pagecolumn34

Downstream Synthesis Route

[1]Hellerman;Stock[JournalofBiologicalChemistry,1938,vol.125,p.784]

[2]Ackermann;England;Kutscher[ZeitschriftfurBiologie(Munich),vol.57,p.180]

[1]Kricheldorf,H.R.;Schultze,J.[Synthesis,1976,p.739-741]

[1]Schmuck,Carsten;Rehm,Thomas;Geiger,Lars;Schaefer,Mathias[JournalofOrganicChemistry,2007,vol.72,#16,p.6162-6170]

[2]Boehm,Jeffrey;Davis,Roderick;Murar,ClaudiaE.;Li,Tindy;McCleland,Brent;Dong,Shuping;Yan,Hongxing;Kerns,Jeffrey;Moody,ChristopherJ.;Wilson,AnthonyJ.;Graves,AlanP.;Mentzer,Mary;Qi,Hongwei;Yonchuk,John;Kou,Jen-Pyng;Foley,Joseph;Sanchez,Yolanda;Podolin,PatriciaL.;Bolognese,Brian;Booth-Genthe,Catherine;Galop,Marc;Wolfe,Lawrence;Carr,Robin;Callahan,JamesF.[BioorganicandMedicinalChemistry,2019,vol.27,#4,p.579-588]

[3]Baldwin,JackE.;Adlington,RobertM.;Crabbe,M.James;Knight,Graham;Nomoto,Takashi;etal.[Tetrahedron,1987,vol.43,#13,p.3009-3014]

[4]Tarozzi,Andrea;Marchetti,Chiara;Nicolini,Benedetta;D'Amico,Massimo;Ticchi,Nicole;Pruccoli,Letizia;Tumiatti,Vincenzo;Simoni,Elena;Lodola,Alessio;Mor,Marco;Milelli,Andrea;Minarini,Anna[EuropeanJournalofMedicinalChemistry,2016,vol.117,p.283-291]

[5]Davies,J.A.etal.[JournaloftheChemicalSocietyC:Organic,1969,p.1358-1363]Ogura,Haruo;Takeda,Kazuyoshi[Heterocycles,1981,vol.15,#1,p.467-468]

[6]LeverJr.;Vestal[JournalofHeterocyclicChemistry,1986,vol.23,#3,p.901-903]

[7]Garcia,ConcepcionFernandez;McKervey,M.Anthony;Ye,Tao[ChemicalCommunications,1996,#12,p.1465-1466]

[8]Sall,DanielJ.;Arfsten,AnnE.;Bastian,JolieA.;Denney,MichaelL.;Harms,CathyS.;McCowan,JeffersonR.;MorinJr.,JohnM.;Rose,JackW.;Scarborough,RobertM.;Smyth,MarkS.;Um,SuzaneL.;Utterback,BarbaraG.;Vasileff,RobertT.;Wikel,JamesH.;Wyss,VirginiaL.;Jakubowski,JosephA.[JournalofMedicinalChemistry,1997,vol.40,#18,p.2843-2857]

[9]Goud,ThirumaniVenkateshwar;Aubertin,Anne-Marie;Biellmann,Jean-Francois[Nucleosides,nucleotidesandnucleicacids,2008,vol.27,#5,p.495-505]

[10]CurrentPatentAssignee:ROCHEHOLDINGAG-WO2018/1952,2018,A1Locationinpatent:Page/Pagecolumn159;160

[11]CurrentPatentAssignee:JOHNSON&JOHNSONINC-WO2022/53010,2022,A1Locationinpatent:Page/Pagecolumn201;207

[1]JournaloftheChemicalSociety.PerkintransactionsI,1969,vol.14,p.1860-1865

[2]JournaloftheAmericanChemicalSociety,1963,vol.85,p.1-8

[3]JournaloftheAmericanSocietyforMassSpectrometry,2014,vol.25,p.1694-1704

[1]ChemistryofHeterocyclicCompounds,1973,vol.9,p.441-446    KhimiyaGeterotsiklicheskikhSoedinenii,1973,vol.9,p.479-485

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SDS
Tags:660-88-8 Molecular Formula|660-88-8 MDL|660-88-8 SMILES|660-88-8 5-Aminovaleric acid