Home Amines 67747-01-7
67747-01-7,MFCD09751307
Catalog No.:AA006JSB

67747-01-7 | N-(2-(2,4,6-Trichlorophenoxy)ethyl)propan-1-amine

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1g
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA006JSB
Chemical Name:
N-(2-(2,4,6-Trichlorophenoxy)ethyl)propan-1-amine
CAS Number:
67747-01-7
Molecular Formula:
C11H14Cl3NO
Molecular Weight:
282.5940
MDL Number:
MFCD09751307
SMILES:
CCCNCCOc1c(Cl)cc(cc1Cl)Cl
Properties
Properties
 
Form:
Solid  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
182  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
16  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
6  
XLogP3:
4.2  

Downstream Synthesis Route

[1]Schaller;Mildenberger;Sachse[ZeitschriftfurNaturforschung,TeilB:AnorganischeChemie,OrganischeChemie,1985,vol.40,#2,p.298-304]

67747-01-7   
Ethyl<<2-(2,4,6-trichlorphenoxy)-ethyl>-propylamido>(imidazol-1-ylamido)phosphat 

[1]Schaller;Mildenberger;Sachse[ZeitschriftfurNaturforschung,TeilB:AnorganischeChemie,OrganischeChemie,1985,vol.40,#2,p.298-304]

67747-01-7   
Ethyl<<2-(2,4,6-trichlorphenoxy)-ethyl>-propylamido>(1,2,4-triazol-1-ylamido)phosphat 

[1]Schaller;Mildenberger;Sachse[ZeitschriftfurNaturforschung,TeilB:AnorganischeChemie,OrganischeChemie,1985,vol.40,#2,p.298-304]

67747-01-7   
Ethyl<<2-(2,4,6-trichlorphenoxy)-ethyl>-propylamido>(2,6-dimethyl-morpholin-4-ylamido)phosphat 

[1]Schaller;Mildenberger;Sachse[ZeitschriftfurNaturforschung,TeilB:AnorganischeChemie,OrganischeChemie,1985,vol.40,#2,p.298-304]

Literature

Title: Association of KCNJ11 E23K gene polymorphism with hypoglycemia in sulfonylurea-treated type 2 diabetic patients.

Journal: Diabetes research and clinical practice 20121001

Title: Gene networks modified by sulphonylureas in beta cells: a pathway-based analysis of insulin secretion and cell death.

Journal: Basic & clinical pharmacology & toxicology 20121001

Title: Blockers of sulfonylureas receptor 1 subunits may lead to cardiac protection against isoprenaline-induced injury in obese rats.

Journal: European journal of pharmacology 20120905

Title: Development of novel gastroretentive floating particulate drug delivery system of gliclazide.

Journal: Current drug delivery 20120901

Title: Protective effect of gliclazide on diabetic peripheral neuropathy through Drp-1 mediated-oxidative stress and apoptosis.

Journal: Neuroscience letters 20120808

Title: Probiotics decreased the bioavailability of the bile acid analog, monoketocholic acid, when coadministered with gliclazide, in healthy but not diabetic rats.

Journal: European journal of drug metabolism and pharmacokinetics 20120601

Title: Physicochemical investigations and stability studies of amorphous gliclazide.

Journal: AAPS PharmSciTech 20120601

Title: Gliclazide may have an antiapoptotic effect related to its antioxidant properties in human normal and cancer cells.

Journal: Molecular biology reports 20120501

Title: Novel tamarind seed polysaccharide-alginate mucoadhesive microspheres for oral gliclazide delivery: in vitro-in vivo evaluation.

Journal: Drug delivery 20120401

Title: KCNJ11 gene E23K variant and therapeutic response to sulfonylureas.

Journal: European journal of internal medicine 20120401

Title: Protective effects of combined therapy of gliclazide with curcumin in experimental diabetic neuropathy in rats.

Journal: Behavioural pharmacology 20120401

Title: Pharmacogenomic analysis of ATP-sensitive potassium channels coexpressing the common type 2 diabetes risk variants E23K and S1369A.

Journal: Pharmacogenetics and genomics 20120301

Title: Variations in tissue selectivity amongst insulin secretagogues: a systematic review.

Journal: Diabetes, obesity & metabolism 20120201

Title: Glycaemic control and cost analysis when changing from gliclazide co-administered with metformin to pre-combined glibenclamide-metformin tablets in type 2 diabetes mellitus.

Journal: The Medical journal of Malaysia 20120201

Title: Effects of pioglitazone add-on to gliclazide and metformin on glycemic control in patients with type 2 diabetes.

Journal: Endocrine research 20120101

Title: Treating diabetes today with gliclazide MR: a matter of numbers.

Journal: Diabetes, obesity & metabolism 20120101

Title: Protective effects of beta glucan and gliclazide on brain tissue and sciatic nerve of diabetic rats induced by streptozosin.

Journal: Experimental diabetes research 20120101

Title: Gliclazide does not fully prevent 2-deoxy-D-ribose-induced oxidative damage because it does not restore glutathione content in a pancreatic β-cell line.

Journal: Oxidative medicine and cellular longevity 20120101

Title: Antidiabetic effect of S-allylcysteine: effect on thyroid hormone and circulatory antioxidant system in experimental diabetic rats.

Journal: Journal of diabetes and its complications 20120101

Title: [Diabetes mellitus and chronic kideny disease: modern diagnostics and treatment].

Journal: Vestnik Rossiiskoi akademii meditsinskikh nauk 20120101

Title: Does glycemic control offer similar benefits among patients with diabetes in different regions of the world? Results from the ADVANCE trial.

Journal: Diabetes care 20111201

Title: Development, optimization, and anti-diabetic activity of gliclazide-loaded alginate-methyl cellulose mucoadhesive microcapsules.

Journal: AAPS PharmSciTech 20111201

Title: [Incretin-based therapy for treating patients with type 2 diabetes].

Journal: Orvosi hetilap 20111127

Title: High-performance affinity chromatography and the analysis of drug interactions with modified proteins: binding of gliclazide with glycated human serum albumin.

Journal: Analytical and bioanalytical chemistry 20111101

Title: [Hypoglycemia].

Journal: Praxis 20111019

Title: Effect of binary and ternary solid dispersions on the in vitro dissolution and in-situ rabbit intestinal absorption of gliclazide.

Journal: Pakistan journal of pharmaceutical sciences 20111001

Title: Dissolution rate enhancement of gliclazide by ordered mixing.

Journal: Acta pharmaceutica (Zagreb, Croatia) 20110901

Title: Antidiabetic and antioxidant potentials of Euphorbia hirta leaves extract studied in streptozotocin-induced experimental diabetes in rats.

Journal: General physiology and biophysics 20110901

Title: AMP-activated protein kinase is activated in adipose tissue of individuals with type 2 diabetes treated with metformin: a randomised glycaemia-controlled crossover study.

Journal: Diabetologia 20110701

Title: Intensive glucose control and risk of cancer in patients with type 2 diabetes.

Journal: Diabetologia 20110701

Title: Comparison of the dipeptidyl peptidase-4 inhibitor vildagliptin and the sulphonylurea gliclazide in combination with metformin, in Muslim patients with type 2 diabetes mellitus fasting during Ramadan: results of the VECTOR study.

Journal: Current medical research and opinion 20110701

Title: Formulation and evaluation of Ficus glomerata mucilage sustained release matrix tablets of gliclazide.

Journal: Pakistan journal of pharmaceutical sciences 20110701

Title: Pharmacokinetic-pharmacodynamic equivalence of three gliclazide formulations in healthy human male subjects.

Journal: International journal of clinical pharmacology and therapeutics 20110701

Title: Reduced catalytic activity of human CYP2C9 natural alleles for gliclazide: molecular dynamics simulation and docking studies.

Journal: Biochimie 20110601

Title: Effects of gliclazide on endothelial function in patients with newly diagnosed type 2 diabetes.

Journal: European journal of pharmacology 20110601

Title: Diagnosis in diabetes: does it matter?

Journal: The journal of the Royal College of Physicians of Edinburgh 20110601

Title: Molecular dynamics simulation of drug uptake by polymer.

Journal: Journal of molecular modeling 20110501

Title: In vitro-in vivo correlation for gliclazide immediate-release tablets based on mechanistic absorption simulation.

Journal: AAPS PharmSciTech 20110301

Title: Insulin and metformin may prevent renal injury in young type 2 diabetic Goto-Kakizaki rats.

Journal: European journal of pharmacology 20110225

Title: Comparison of two sulfonylureas with high and low myocardial K(ATP) channel affinity on myocardial infarct size and metabolism in a rat model of type 2 diabetes.

Journal: Diabetologia 20110201

Title: Design and development of gliclazide-loaded chitosan microparticles for oral sustained drug delivery: in-vitro/in-vivo evaluation.

Journal: The Journal of pharmacy and pharmacology 20110201

Title: Design and development of gliclazide-loaded chitosan for oral sustained drug delivery: in vitro/in vivo evaluation.

Journal: Journal of microencapsulation 20110101

Title: Response to oral gliclazide in a pre-pubertal child with hepatic nuclear factor-1 alpha maturity onset diabetes of the young.

Journal: Annals of Saudi medicine 20110101

Title: Effect of repaglinide and gliclazide on glycaemic control, early-phase insulin secretion and lipid profiles in.

Journal: Chinese medical journal 20110101

Title: Ramsay Hunt syndrome with unilateral polyneuropathy involving cranial nerves V, VII, VIII, and XII in a diabetic patient.

Journal: Quintessence international (Berlin, Germany : 1985) 20110101

Title: [Comparative characteristics of antioxidant properties of hypoglycemic agents diabenol and gliclazide].

Journal: Eksperimental'naia i klinicheskaia farmakologiia 20110101

Title: Design and evaluation of a novel formulation prediction system.

Journal: International journal of pharmaceutics 20101215

Title: Antidiabetic effect of S-allylcysteine: Effect on plasma and tissue glycoproteins in experimental diabetes.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20101201

Title: Beneficial effect of S-allylcysteine (SAC) on blood glucose and pancreatic antioxidant system in streptozotocin diabetic rats.

Journal: Plant foods for human nutrition (Dordrecht, Netherlands) 20101201

Title: Hydrochloride pioglitazone decreases urinary cytokines excretion in type 2 diabetes.

Journal: Clinical endocrinology 20101201

Title: Use of sulphonylurea and cancer in type 2 diabetes-The Hong Kong Diabetes Registry.

Journal: Diabetes research and clinical practice 20101201

Title: Erectile dysfunction and later cardiovascular disease in men with type 2 diabetes: prospective cohort study based on the ADVANCE (Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified-Release Controlled Evaluation) trial.

Journal: Journal of the American College of Cardiology 20101130

Title: Severe hypoglycemia and risks of vascular events and death.

Journal: The New England journal of medicine 20101007

Title: Effects of metformin plus gliclazide compared with metformin alone on circulating endothelial progenitor cell in type 2 diabetic patients.

Journal: Endocrine 20101001

Title: Effects of gliclazide on platelet aggregation and the plasminogen activator inhibitor type 1 level in patients with type 2 diabetes mellitus.

Journal: Metabolism: clinical and experimental 20100901

Title: Physicochemical characterization of gliclazide-macrogol solid dispersion and tablets based on optimized dispersion.

Journal: Drug development and industrial pharmacy 20100801

Title: The efficacy of lowering glycated haemoglobin with a gliclazide modified release-based intensive glucose lowering regimen in the ADVANCE trial.

Journal: Diabetes research and clinical practice 20100801

Title: Resveratrol attenuates hyperglycemia-mediated oxidative stress, proinflammatory cytokines and protects hepatocytes ultrastructure in streptozotocin-nicotinamide-induced experimental diabetic rats.

Journal: Chemico-biological interactions 20100730

Title: Preparation and in vitro evaluation of gliclazide sustained-release matrix pellets: formulation and storage stability.

Journal: Drug development and industrial pharmacy 20100701

Title: Maintenance of glycaemic control with the evening administration of a long acting sulphonylurea in male type 2 diabetic patients undertaking the Ramadan fast.

Journal: International journal of clinical practice 20100701

Title: Gliclazide microcrystals prepared by two methods of in situ micronization: pharmacokinetic studies in diabetic and normal rats.

Journal: AAPS PharmSciTech 20100601

Title: Effect of gliclazide on nucleotide excision repair (NER) and non-homologous DNA end joining (NHEJ) in normal and cancer cells.

Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20100601

Title: Influence of CYP2C9 and CYP2C19 genetic polymorphisms on pharmacokinetics and pharmacodynamics of gliclazide in healthy Chinese Han volunteers.

Journal: Journal of clinical pharmacy and therapeutics 20100601

Title: Three novel mutations in MODY and its phenotype in three different Czech families.

Journal: Diabetes research and clinical practice 20100501

Title: Effects of short-term therapy with different insulin secretagogues on glucose metabolism, lipid parameters and oxidative stress in newly diagnosed Type 2 Diabetes Mellitus.

Journal: Diabetes research and clinical practice 20100401

Title: Comparison of ultraviolet detection, evaporative light scattering detection and charged aerosol detection methods for liquid-chromatographic determination of anti-diabetic drugs.

Journal: Journal of pharmaceutical and biomedical analysis 20100311

Title: Comparison of insulin sensitivity, glucose sensitivity, and first phase insulin secretion in patients treated with repaglinide or gliclazide.

Journal: Archives of pharmacal research 20100301

Title: Comparison of metformin, gliclazide MR and rosiglitazone in monotherapy and in combination for type 2 diabetes.

Journal: Arquivos brasileiros de endocrinologia e metabologia 20100301

Title: A comparison of efficacy and safety of vildagliptin and gliclazide in combination with metformin in patients with Type 2 diabetes inadequately controlled with metformin alone: a 52-week, randomized study.

Journal: Diabetic medicine : a journal of the British Diabetic Association 20100301

Title: Evaluation of different tests based on observations for external model evaluation of population analyses.

Journal: Journal of pharmacokinetics and pharmacodynamics 20100201

Title: Evaluation of efficacy and tolerability of gliclazide and metformin combination: a multicentric study in patients with type 2 diabetes mellitus uncontrolled on monotherapy with sulfonylurea or metformin.

Journal: American journal of therapeutics 20100101

Title: Present status of sulfonylurea treatment for type 2 diabetes in Japan: second report of a cross-sectional survey of 15,652 patients.

Journal: Endocrine journal 20100101

Title: [Dynamics of structural-functional parameters of cardiovascular system during use of complex therapy of women with type 2 diabetes mellitus].

Journal: Kardiologiia 20100101

Title: [Capabilities of hypoglycemic therapy in women with decompensated type 2 diabetes mellitus].

Journal: Terapevticheskii arkhiv 20100101

Title: Sulphonylureas and cancer: a case-control study.

Journal: Acta diabetologica 20091201

Title: Efficacy and safety comparison between the DPP-4 inhibitor vildagliptin and the sulfonylurea gliclazide after two years of monotherapy in drug-naïve patients with type 2 diabetes.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20091201

Title: Glibenclamide-related excess in total and cardiovascular mortality risks: data from large Ukrainian observational cohort study.

Journal: Diabetes research and clinical practice 20091201

Title: Pharmacokinetics and bioequivalence evaluation of gliclazide/metformin combination tablet and equivalent doses of gliclazide and metformin in healthy Korean subjects.

Journal: International journal of clinical pharmacology and therapeutics 20091201

Title: Recent cardiovascular trials: what are the drivers of benefit and adverse effect?

Journal: Journal of diabetes 20091201

Title: Suppression of KATP channel activity protects murine pancreatic beta cells against oxidative stress.

Journal: The Journal of clinical investigation 20091102

Title: Combined effects of routine blood pressure lowering and intensive glucose control on macrovascular and microvascular outcomes in patients with type 2 diabetes: New results from the ADVANCE trial.

Journal: Diabetes care 20091101

Title: Cognitive function and risks of cardiovascular disease and hypoglycaemia in patients with type 2 diabetes: the Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified Release Controlled Evaluation (ADVANCE) trial.

Journal: Diabetologia 20091101

Title: Is there evidence that oral hypoglycemic agents reduce cardiovascular morbidity or mortality? No.

Journal: Diabetes care 20091101

Title: Severe neuroglycopaenia secondary to severe hypoglycaemia from serendipitous overdose of gliclazide without adrenergic or autonomic response.

Journal: Diabetic medicine : a journal of the British Diabetic Association 20091101

Title: Effect of gliclazide immobilization into layered double hydroxide on drug release.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20091001

Title: Vildagliptin therapy and hypoglycaemia in Muslim type 2 diabetes patients during Ramadan.

Journal: International journal of clinical practice 20091001

Title: Trace analysis of glyclazide in human plasma at microscale level by mass spectrometry.

Journal: Journal of separation science 20091001

Title: Second-generation sulfonylureas preserve inhibition of mitochondrial permeability transition by the mitochondrial K+(ATP) opener nicorandil in experimental myocardial infarction.

Journal: Shock (Augusta, Ga.) 20090901

Title: Effects of exposure of human islet beta-cells to normal and high glucose levels with or without gliclazide or glibenclamide.

Journal: Diabetes & metabolism 20090901

Title: D-pinitol attenuates the impaired activities of hepatic key enzymes in carbohydrate metabolism of streptozotocin-induced diabetic rats.

Journal: General physiology and biophysics 20090901

Title: Pioglitazone-induced acute rhabdomyolysis.

Journal: Diabetes care 20090701

Title: The behavior of Gliclazide in solution and in the solid state: a case of organic compound presenting a solid-solution structure.

Journal: Magnetic resonance in chemistry : MRC 20090601

Title: Physicochemical properties of solid dispersions of gliclazide in polyvinylpyrrolidone K90.

Journal: AAPS PharmSciTech 20090601

Title: Modulatory effects of resveratrol on attenuating the key enzymes activities of carbohydrate metabolism in streptozotocin-nicotinamide-induced diabetic rats.

Journal: Chemico-biological interactions 20090515

Title: The oral anti-diabetic agent, gliclazide, inhibits oxidized LDL-mediated LOX-1 expression, metalloproteinase-9 secretion and apoptosis in human aortic endothelial cells.

Journal: Atherosclerosis 20090501

Title: Blood pressure and glucose control in subjects with diabetes: new analyses from ADVANCE.

Journal: Journal of hypertension. Supplement : official journal of the International Society of Hypertension 20090501

Title: In vive effects of gliclazide and metformin on the plasma concentration of caffeine in healthy rats.

Journal: Pakistan journal of biological sciences : PJBS 20090501

Title: Overcome side identification in PPOP by making orifices on both layers.

Journal: International journal of pharmaceutics 20090417

Title: Free fatty acid kinetics during long-term treatment with pioglitazone added to sulfonylurea or metformin in Type 2 diabetes.

Journal: Journal of internal medicine 20090401

Title: Applying the Taguchi design for optimized formulation of sustained release gliclazide chitosan beads: an in vitro/in vivo study.

Journal: AAPS PharmSciTech 20090301

Title: Antidiabetic effects of dipeptidyl peptidase-IV inhibitors and sulfonylureas in streptozotocin-nicotinamide-induced mildly diabetic mice.

Journal: Metabolism: clinical and experimental 20090301

Title: Preparation and characterization of gliclazide-polyethylene glycol 4000 solid dispersions.

Journal: Acta pharmaceutica (Zagreb, Croatia) 20090301

Title: The metabolism of CYP2C9 and CYP2C19 for gliclazide by homology modeling and docking study.

Journal: European journal of medicinal chemistry 20090201

Title: Unexplained severe hypoglycaemia in hospital: a difficult diagnostic challenge.

Journal: British journal of clinical pharmacology 20090201

Title: Treatment of HNF1-alpha MODY with the DPP-4 inhibitor Sitagliptin(1).

Journal: Diabetic medicine : a journal of the British Diabetic Association 20090201

Title: Antioxidant and vascular effects of gliclazide in type 2 diabetic rats fed high-fat diet.

Journal: Physiological research 20090101

Title: Normal insulin response to short-term intense exercise is abolished in Type 2 diabetic patients treated with gliclazide.

Journal: Journal of diabetes and its complications 20090101

Title: Normal pregnancy and healthy child after continued exposure to gliclazide and ramipril during pregnancy.

Journal: The Annals of pharmacotherapy 20090101

Title: Gliclazide reduces MKC intestinal transport in healthy but not diabetic rats.

Journal: European journal of drug metabolism and pharmacokinetics 20090101

Title: Dissolution enhancement of gliclazide using pH change approach in presence of twelve stabilizers with various physico-chemical properties.

Journal: Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20090101

Title: The efficacy of self-monitoring of blood glucose in the management of patients with type 2 diabetes treated with a gliclazide modified release-based regimen. A multicentre, randomized, parallel-group, 6-month evaluation (DINAMIC 1 study).

Journal: Diabetes, obesity & metabolism 20081201

Title: Hyperglycaemia secondary to mirtazapine therapy in a 37-year-old man.

Journal: The Australian and New Zealand journal of psychiatry 20081101

Title: Ser1369Ala variant in sulfonylurea receptor gene ABCC8 is associated with antidiabetic efficacy of gliclazide in Chinese type 2 diabetic patients.

Journal: Diabetes care 20081001

Title: Comparison of gliclazide with insulin as initial treatment modality in newly diagnosed type 2 diabetes.

Journal: Diabetes technology & therapeutics 20081001

Title: optimization of extended zero-order release gliclazide tablets using D-optimal mixture design.

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20081001

Title: Reversible binding of antidiabetic drugs, repaglinide and gliclazide, with human serum albumin.

Journal: Chemical biology & drug design 20081001

Title: Daily blood glucose profiles of glibenclamide and gliclazide taken once or twice daily in elderly type 2 diabetic patients.

Journal: Geriatrics & gerontology international 20080901

Title: Differential effect of sulfonylureas on production of reactive oxygen species and apoptosis in cultured pancreatic beta-cell line, MIN6.

Journal: Metabolism: clinical and experimental 20080801

Title: Is Ramadan fasting safe in type 2 diabetic patients in view of the lack of significant effect of fasting on clinical and biochemical parameters, blood pressure, and glycemic control?

Journal: Clinical and experimental hypertension (New York, N.Y. : 1993) 20080701

Title: In vitro effect of gliclazide on DNA damage and repair in patients with type 2 diabetes mellitus (T2DM).

Journal: Chemico-biological interactions 20080617

Title: Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes.

Journal: The New England journal of medicine 20080612

Title: Enhancement of dissolution rate of gliclazide using solid dispersions with polyethylene glycol 6000.

Journal: AAPS PharmSciTech 20080601

Title: Rosiglitazone produces a greater reduction in circulating platelet activity compared with gliclazide in patients with type 2 diabetes mellitus--an effect probably mediated by direct platelet PPARgamma activation.

Journal: Atherosclerosis 20080401

Title: Effects of St John's wort and CYP2C9 genotype on the pharmacokinetics and pharmacodynamics of gliclazide.

Journal: British journal of pharmacology 20080401

Title: Erythromelalgia in a diabetic patient managed with gabapentin.

Journal: Diabetes research and clinical practice 20080301

Title: Therapeutic options for elderly diabetic subjects: open label, randomized clinical trial of insulin glargine added to oral antidiabetic drugs versus increased dosage of oral antidiabetic drugs.

Journal: Acta diabetologica 20080301

Title: Spermicidal activity of sulfonylureas and meglitinide analogues: role of intrasperm Ca2+ elevation.

Journal: The Journal of pharmacy and pharmacology 20080301

Title: Design and development of gliclazide mucoadhesive microcapsules: in vitro and in vivo evaluation.

Journal: AAPS PharmSciTech 20080301

Title: [Effects of Tangweian granule on 5-HT(2A)R in rat model with diabetic gastroparesis].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080301

Title: Influence of the semisynthetic bile acid MKC on the ileal permeation of gliclazide in vitro in healthy and diabetic rats treated with probiotics.

Journal: Methods and findings in experimental and clinical pharmacology 20080301

Title: Antiglycation effect of gliclazide on in vitro AGE formation from glucose and methylglyoxal.

Journal: Experimental biology and medicine (Maywood, N.J.) 20080201

Title: Hypoglycemic effects of a sesquiterpene glycoside isolated from leaves of loquat (Eriobotrya japonica (Thunb.) Lindl.).

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20080101

Title: Decreased in vivo oxidative stress and decreased platelet activation following metformin treatment in newly diagnosed type 2 diabetic subjects.

Journal: Diabetes/metabolism research and reviews 20080101

Title: Evaluation of gliclazide ability to attenuate the hyperglycaemic 'memory' induced by high glucose in isolated human endothelial cells.

Journal: Diabetes/metabolism research and reviews 20080101

Title: Development of extended zero-order release gliclazide tablets by central composite design.

Journal: Drug development and industrial pharmacy 20080101

Title: Probiotic treatment reduces blood glucose levels and increases systemic absorption of gliclazide in diabetic rats.

Journal: European journal of drug metabolism and pharmacokinetics 20080101

Title: Influence of the semisynthetic bile acid (MKC) on the ileal permeation of gliclazide in healthy and diabetic rats.

Journal: Pharmacological reports : PR 20080101

Title: Vascular and renal benefits are additive using intensive blood pressure control and incremental glucose control in type 2 diabetic patients.

Journal: Cardiovascular journal of Africa 20080101

Title: The influence of 3alpha,7alpha-dihydroxy-12-keto-5beta-cholanate on gliclazide pharmacokinetics and glucose levels in a rat model of diabetes.

Journal: European journal of drug metabolism and pharmacokinetics 20080101

Title: Liquid chromatography--mass spectrometry method for the determination of gliclazide in human plasma and application to a pharmacokinetic study of gliclazide sustained release tablets.

Journal: Arzneimittel-Forschung 20080101

Title: Gliclazide inhibits proliferation but stimulates differentiation of white and brown adipocytes.

Journal: Journal of biochemistry 20071101

Title: Identification of the human cytochromes P450 catalysing the rate-limiting pathways of gliclazide elimination.

Journal: British journal of clinical pharmacology 20071001

Title: The influence of hydro-alcoholic media on hypromellose matrix systems.

Journal: Drug development and industrial pharmacy 20071001

Title: [Advanced credit: patient enrolling and therapy initiation in the ADVANCE trial].

Journal: Orvosi hetilap 20070930

Title: Are sulphonylureas all the same? A cohort study on cardiovascular and cancer-related mortality.

Journal: Diabetes/metabolism research and reviews 20070901

Title: 'Warm-up' phenomenon in diabetic patients with stable angina treated with diet or sulfonylureas.

Journal: Coronary artery disease 20070901

Title: Long-term effects of pioglitazone versus gliclazide on hepatic and humoral coagulation factors in patients with type 2 diabetes.

Journal: Diabetes & vascular disease research 20070901

Title: Effects of glibenclamide, glimepiride, and gliclazide on ischemic preconditioning in rat heart.

Journal: Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih 20070901

Title: Controlling of systemic absorption of gliclazide through incorporation into alginate beads.

Journal: International journal of pharmaceutics 20070816

Title: Comparisons between the beneficial effects of different sulphonylurea treatments on ischemia-induced retinal neovascularization.

Journal: Free radical biology & medicine 20070801

Title: Association of sulfonylurea receptor 1 genotype with therapeutic response to gliclazide in type 2 diabetes.

Journal: Diabetes research and clinical practice 20070701

Title: Influence of CYP2C9 and CYP2C19 genetic polymorphisms on pharmacokinetics of gliclazide MR in Chinese subjects.

Journal: British journal of clinical pharmacology 20070701

Title: Gliclazide: pharmacokinetic-pharmacodynamic relationships in rats.

Journal: Biopharmaceutics & drug disposition 20070701

Title: Nateglinide or gliclazide in combination with metformin for treatment of patients with type 2 diabetes mellitus inadequately controlled on maximum doses of metformin alone: 1-year trial results.

Journal: Diabetes, obesity & metabolism 20070701

Title: In-vitro and in-vivo correlation for two gliclazide extended-release tablets.

Journal: The Journal of pharmacy and pharmacology 20070701

Title: Development of a RP-HPLC method for screening potentially counterfeit anti-diabetic drugs.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070615

Title: New insights from ADVANCE.

Journal: Journal of hypertension. Supplement : official journal of the International Society of Hypertension 20070601

Title: Insulinoma causing hypoglycemia in a patient with type 2 diabetes.

Journal: Journal of the Formosan Medical Association = Taiwan yi zhi 20070501

Title: Mixture modeling for the detection of subpopulations in a pharmacokinetic/pharmacodynamic analysis.

Journal: Journal of pharmacokinetics and pharmacodynamics 20070401

Title: Gliclazide protects human islet beta-cells from apoptosis induced by intermittent high glucose.

Journal: Diabetes/metabolism research and reviews 20070301

Title: A bioequivalence study of gliclazide based on quantification by high-performance liquid chromatography coupled with electrospray tandem mass spectrometry.

Journal: International journal of clinical pharmacology and therapeutics 20070301

Title: Comparison of the solubility and dissolution rate between gliclazide solid complex and its nanospheres.

Journal: Drug development and industrial pharmacy 20070301

Title: Dual aetiologies for hyperinsulinaemic hypoglycaemia in one patient.

Journal: Hong Kong medical journal = Xianggang yi xue za zhi 20070201

Title: Preparation and in vitro/in vivo evaluation of gliclazide loaded Eudragit nanoparticles as a sustained release carriers.

Journal: Drug development and industrial pharmacy 20070201

Title: Beneficial effects of gliclazide modified release compared with glibenclamide on endothelial activation and low-grade inflammation in patients with type 2 diabetes.

Journal: Diabetes, obesity & metabolism 20070101

Title: The mushroom Agaricus Blazei Murill in combination with metformin and gliclazide improves insulin resistance in type 2 diabetes: a randomized, double-blinded, and placebo-controlled clinical trial.

Journal: Journal of alternative and complementary medicine (New York, N.Y.) 20070101

Title: Impact of the short-term, intense exercise on postprandial glycemia in type 2 diabetic patients treated with gliclazide.

Journal: Journal of diabetes and its complications 20070101

Title: In vivo and in vitro evaluation of a solid dispersion system of gliclazide:PEG 6000.

Journal: PDA journal of pharmaceutical science and technology 20070101

Title: A case of mistaken identity.

Journal: Hong Kong medical journal = Xianggang yi xue za zhi 20061201

Title: Effect of Kaiyu Qingwei Jianji on the morphometry and residual strain distribution of small intestine in experimental diabetic rats.

Journal: World journal of gastroenterology 20061128

Title: Association of gliclazide and left ventricular mass in type 2 diabetic patients.

Journal: Diabetes research and clinical practice 20061101

Title: Actions of ZD0947, a novel ATP-sensitive K+ channel opener, on membrane currents in human detrusor myocytes.

Journal: British journal of pharmacology 20061101

Title: Activation of nicotinamide adenine dinucleotide phosphate (reduced form) oxidase by advanced glycation end products links oxidative stress to altered retinal vascular endothelial growth factor expression.

Journal: Metabolism: clinical and experimental 20061101

Title: Effects of isopropyl palmitate on the skin permeation of drugs.

Journal: Biological & pharmaceutical bulletin 20061101

Title: Application of monolithic column in quantification of gliclazide in human plasma by liquid chromatography.

Journal: Journal of pharmaceutical and biomedical analysis 20061011

Title: Simultaneous estimation of six anti-diabetic drugs--glibenclamide, gliclazide, glipizide, pioglitazone, repaglinide and rosiglitazone: development of a novel HPLC method for use in the analysis of pharmaceutical formulations and its application to human plasma assay.

Journal: Biomedical chromatography : BMC 20061001

Title: Influence of nicorandil on the pharmacodynamics and pharmacokinetics of gliclazide in rats and rabbits.

Journal: Molecular and cellular biochemistry 20061001

Title: Effect of gliclazide modified release on adiponectin, interleukin-6, and tumor necrosis factor-alpha plasma levels in individuals with type 2 diabetes mellitus.

Journal: Current medical research and opinion 20061001

Title: Effect of gliclazide on DNA damage in human peripheral blood lymphocytes and insulinoma mouse cells.

Journal: Chemico-biological interactions 20060925

Title: Metrics for external model evaluation with an application to the population pharmacokinetics of gliclazide.

Journal: Pharmaceutical research 20060901

Title: Gliclazide treatment lowers serum ICAM-1 levels in poorly controlled type 2 diabetic patients.

Journal: Diabetes & metabolism 20060901

Title: Clinical observation on effect of Kaixin capsule in treating 40 patients with diabetic myocardial ischemia.

Journal: Chinese journal of integrative medicine 20060901

Title: ADVANCE: breaking new ground in type 2 diabetes.

Journal: Journal of hypertension. Supplement : official journal of the International Society of Hypertension 20060801

Title: Antidiabetic activity of an ethanol extract obtained from the stem bark of Psidium guajava (Myrtaceae).

Journal: Die Pharmazie 20060801

Title: [Rhabdomyolysis induced by fenofibrate monotherapy].

Journal: La Revue de medecine interne 20060701

Title: Is it time to re-assess the role of gliclazide? Targeting insulin resistance in type 2 diabetes patients suboptimally controlled with insulin.

Journal: Postgraduate medical journal 20060701

Title: Comparison of nateglinide and gliclazide in combination with metformin, for treatment of patients with Type 2 diabetes mellitus inadequately controlled on maximum doses of metformin alone.

Journal: Diabetic medicine : a journal of the British Diabetic Association 20060701

Title: A mechanism-based disease progression model for comparison of long-term effects of pioglitazone, metformin and gliclazide on disease processes underlying Type 2 Diabetes Mellitus.

Journal: Journal of pharmacokinetics and pharmacodynamics 20060601

Title: Gliclazide protects 3T3L1 adipocytes against insulin resistance induced by hydrogen peroxide with restoration of GLUT4 translocation.

Journal: Metabolism: clinical and experimental 20060601

Title: Gliclazide inhibits differentiation-associated biologic events in human monocyte-derived macrophages.

Journal: Metabolism: clinical and experimental 20060601

Title: Effects of gliclazide beyond metabolic control.

Journal: Metabolism: clinical and experimental 20060501

Title: Lymphocyte ecto-5'-nucleotidase in obese type 2 diabetic patients treated with gliclazide.

Journal: Diabetes & metabolism 20060401

Title: Double-blind, randomized, multicentre study of the efficacy and safety of gliclazide-modified release in the treatment of Chinese type 2 diabetic patients.

Journal: Diabetes, obesity & metabolism 20060301

Title: Comparison of glycaemic control over 1 year with pioglitazone or gliclazide in patients with Type 2 diabetes.

Journal: Diabetic medicine : a journal of the British Diabetic Association 20060301

Title: Anti-diabetic and hypolipidemic effects of aqueous-extract from the flower of Inula japonica in alloxan-induced diabetic mice.

Journal: Biological & pharmaceutical bulletin 20060301

Title: Influence of selenium (antioxidant) on gliclazide induced hypoglycaemia/anti hyperglycaemia in normal/alloxan-induced diabetic rats.

Journal: Molecular and cellular biochemistry 20060201

Title: Comparison of the antioxidant and vascular effects of gliclazide and glibenclamide in Type 2 diabetic patients: a randomized crossover study.

Journal: Journal of diabetes and its complications 20060101

Title: Three-year mortality in diabetic patients treated with different combinations of insulin secretagogues and metformin.

Journal: Diabetes/metabolism research and reviews 20060101

Title: Development and validation of a new high-performance liquid chromatography method for the determination of gliclazide and repaglinide in pharmaceutical formulations.

Journal: Journal of AOAC International 20060101

Title: Single and multiple dose bioequivalence evaluation of two brands of gliclazide modified release tablets in healthy Chinese male volunteers.

Journal: Arzneimittel-Forschung 20060101

Title: The effectiveness of various doses of octreotide for sulfonylurea-induced hypoglycemia after overdose.

Journal: Advances in therapy 20060101

Title: Secondary sulfonylurea failure: comparison of period until insulin treatment between diabetic patients treated with gliclazide and glibenclamide.

Journal: Diabetes research and clinical practice 20051201

Title: Activation of KATP channels by H2S in rat insulin-secreting cells and the underlying mechanisms.

Journal: The Journal of physiology 20051201

Title: Long-term effects on lipids and lipoproteins of pioglitazone versus gliclazide addition to metformin and pioglitazone versus metformin addition to sulphonylurea in the treatment of type 2 diabetes.

Journal: Diabetologia 20051201

Title: The DIACOM study (effect of DosIng frequency of oral Antidiabetic agents on the COMpliance and biochemical control of type 2 diabetes).

Journal: Diabetes, obesity & metabolism 20051101

Title: Simultaneous determination of metformin and gliclazide in human plasma by liquid chromatography-tandem mass spectrometry: application to a bioequivalence study of two formulations in healthy volunteers.

Journal: Journal of mass spectrometry : JMS 20051101

Title: [The multi-level Meta analysis model combining individual level data with aggregative level data].

Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20051101

Title: Safety and tolerability of pioglitazone, metformin, and gliclazide in the treatment of type 2 diabetes.

Journal: Diabetes research and clinical practice 20051001

Title: Synthesis and characterization of gliclazide complexes of magnesium, calcium, chromium, manganese, iron, nickel, copper, zinc and cadmium salts.

Journal: Pakistan journal of pharmaceutical sciences 20051001

Title: [A multicenter clinic study of slow-release-gliclazide in type 2 diabetes mellitus].

Journal: Zhonghua yi xue za zhi 20050928

Title: High-performance liquid chromatography with electrochemical detection for analysis of gliclazide in plasma.

Journal: Journal of chromatography. A 20050923

Title: Determination of aminoheterocycle and azabicycle in gliclazide bulk by capillary zone electrophoresis with amperometric detection.

Journal: Journal of pharmaceutical and biomedical analysis 20050915

Title: Management of diabetes during Ramadan.

Journal: Diabetic medicine : a journal of the British Diabetic Association 20050901

Title: Gliclazide attenuates the intracellular Ca2+ changes induced in vitro by ischemia in the retinal slices of rats with streptozotocin-induced diabetes.

Journal: Current eye research 20050901

Title: Changes in liver tests during 1-year treatment of patients with Type 2 diabetes with pioglitazone, metformin or gliclazide.

Journal: Diabetic medicine : a journal of the British Diabetic Association 20050801

Title: Confusing tablets.

Journal: Lancet (London, England) 20050701

Title: Long-term efficacy and tolerability of add-on pioglitazone therapy to failing monotherapy compared with addition of gliclazide or metformin in patients with type 2 diabetes.

Journal: Diabetologia 20050601

Title: Pharmaceutical availability of gliclazide from selected matrix formulation tablets.

Journal: Medical science monitor : international medical journal of experimental and clinical research 20050601

Title: Efficacy of glimepiride in Japanese type 2 diabetic subjects.

Journal: Diabetes research and clinical practice 20050601

Title: The effect of gliclazide and glibenclamide on preconditioning of the human myocardium.

Journal: European journal of pharmacology 20050516

Title: [Controversial therapeutic strategies in the treatment of type 2 diabetes mellitus].

Journal: MMW Fortschritte der Medizin 20050428

Title: A long-term comparison of pioglitazone and gliclazide in patients with Type 2 diabetes mellitus: a randomized, double-blind, parallel-group comparison trial.

Journal: Diabetic medicine : a journal of the British Diabetic Association 20050401

Title: The development and validation of liquid chromatography method for the simultaneous determination of metformin and glipizide, gliclazide, glibenclamide or glimperide in plasma.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050325

Title: [54-year-old patient with type 2 diabetes mellitus and increased blood pressure values].

Journal: Praxis 20050316

Title: Comparison of pioglitazone and gliclazide in sustaining glycemic control over 2 years in patients with type 2 diabetes.

Journal: Diabetes care 20050301

Title: Pioglitazone elicits long-term improvements in insulin sensitivity in patients with type 2 diabetes: comparisons with gliclazide-based regimens.

Journal: Diabetologia 20050301

Title: The effect of short-term glycemic regulation with gliclazide and metformin on postprandial lipemia.

Journal: Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20050201

Title: Long-term therapy with addition of pioglitazone to metformin compared with the addition of gliclazide to metformin in patients with type 2 diabetes: a randomized, comparative study.

Journal: Diabetes/metabolism research and reviews 20050101

Title: Effect of repaglinide and gliclazide on postprandial control of endogenous glucose production.

Journal: Metabolism: clinical and experimental 20050101

Title: Forearm vascular reactivity is differentially influenced by gliclazide and glibenclamide in chronically treated type 2 diabetic patients.

Journal: Clinical physiology and functional imaging 20050101

Title: Gliclazide modified release.

Journal: Drugs 20050101

Title: Effect of I-deprenyl and gliclazide on oxidant stress/antioxidant status and dna damage in a diabetic rat model.

Journal: Endocrine research 20050101

Title: Effect of aqueous extract of Cyamopsis tetragonoloba Linn. beans on blood glucose level in normal and alloxan-induced diabetic rats.

Journal: Indian journal of experimental biology 20041201

Title: Gliclazide modified release: results of a 2-year study in patients with type 2 diabetes.

Journal: Diabetes, obesity & metabolism 20041101

Title: Metformin or gliclazide, rather than glibenclamide, attenuate progression of carotid intima-media thickness in subjects with type 2 diabetes.

Journal: Diabetologia 20041101

Title: Effects of pioglitazone on the components of diabetic dyslipidaemia: results of double-blind, multicentre, randomised studies.

Journal: International journal of clinical practice 20041001

Title: [Therapy objectives and daily practice--to which extent are blood sugar target values accessible in daily practice?].

Journal: Praxis 20040929

Title: Taurine block of cloned ATP-sensitive K+ channels with different sulfonylurea receptor subunits expressed in Xenopus laevis oocytes.

Journal: Biochemical pharmacology 20040901

Title: Cardiovascular effects of treatment of type 2 diabetes with pioglitazone, metformin and gliclazide.

Journal: International journal of clinical practice 20040901

Title: Studies on the glycemic and lipidemic effect of monopril and losartan in normal and diabetic rats.

Journal: Pharmacological research 20040801

Title: GUIDE study: double-blind comparison of once-daily gliclazide MR and glimepiride in type 2 diabetic patients.

Journal: European journal of clinical investigation 20040801

Title: Efficacy and safety of once daily gliclazide (20 mg/day) compared with nateglinide.

Journal: Endocrine journal 20040801

Title: [2-year data of large clinical comparative studies. Type 2 diabetes: lasting metabolic control with pioglitazone].

Journal: MMW Fortschritte der Medizin 20040722

Title: [The efficacy and safety of 30 mg slow-released-gliclazide in type 2 diabetes mellitus].

Journal: Zhonghua nei ke za zhi 20040701

Title: Quantification of gliclazide by semi-micro high-performance liquid chromatography: application to a bioequivalence study of two formulations in healthy subjects.

Journal: Journal of pharmaceutical and biomedical analysis 20040629

Title: Advanced glycation end-products increase monocyte adhesion to retinal endothelial cells through vascular endothelial growth factor-induced ICAM-1 expression: inhibitory effect of antioxidants.

Journal: Journal of leukocyte biology 20040601

Title: Metformin attenuates progression of carotid arterial wall thickness in patients with type 2 diabetes.

Journal: Diabetes research and clinical practice 20040601

Title: Normal pregnancy outcome following inadvertent exposure to rosiglitazone, gliclazide, and atorvastatin in a diabetic and hypertensive woman.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20040601

Title: Comparison of uptitration of gliclazide with the addition of rosiglitazone to gliclazide in patients with type 2 diabetes inadequately controlled on half-maximal doses of a sulphonylurea.

Journal: Acta diabetologica 20040601

Title: Octreotide treatment for sulfonylurea-induced hypoglycaemia.

Journal: The Medical journal of Australia 20040517

Title: Gliclazide at a lower concentration than therapeutic dose increases the sensitivity of insulin secretion to glucose in perfused rat pancreas.

Journal: Diabetes & metabolism 20040401

Title: [Long-term HbA1c stable. Insulin sensitizer keeps diabetes in check].

Journal: MMW Fortschritte der Medizin 20040325

Title: Erosion induced controllable release of gliclazide encapsulated inside degradable polymeric particles.

Journal: Macromolecular bioscience 20040315

Title: Signalling pathways involved in retinal endothelial cell proliferation induced by advanced glycation end products: inhibitory effect of gliclazide.

Journal: Diabetes, obesity & metabolism 20040301

Title: NMDA receptor subunits 2A and 2B decrease and lipid peroxidation increase in the hippocampus of streptozotocin-diabetic rats: effects of insulin and gliclazide treatments.

Journal: The International journal of neuroscience 20040301

Title: Radical scavenging effect of gliclazide in diabetic rats fed with a high cholesterol diet.

Journal: Kidney international 20040301

Title: Effect of antidiabetic medications on microalbuminuria in patients with type 2 diabetes.

Journal: Metabolism: clinical and experimental 20040301

Title: Myocardial protection from either ischaemic preconditioning or nicorandil is not blocked by gliclazide.

Journal: Cardiovascular drugs and therapy 20040301

Title: [Compliance and optimisation of oral antidiabetic therapy. A longitudinal study].

Journal: Presse medicale (Paris, France : 1983) 20040214

Title: Phosphatidylinositol 3-kinase activation is required for sulfonylurea stimulation of glucose transport in rat skeletal muscle.

Journal: Endocrinology 20040201

Title: Long-term glycaemic control with pioglitazone in patients with type 2 diabetes.

Journal: International journal of clinical practice 20040201

Title: Favorable effects of pioglitazone and metformin compared with gliclazide on lipoprotein subfractions in overweight patients with early type 2 diabetes.

Journal: Diabetes care 20040101

Title: Protective actions of gliclazide on high insulin-enhanced neutrophil-endothelial cell interactions through inhibition of mitogen activated protein kinase and protein kinase C pathways.

Journal: Microvascular research 20040101

Title: Spectrophotometric determination of gliclazide in pharmaceuticals and biological fluids through ternary complex formation with eosin and palladium (II).

Journal: Farmaco (Societa chimica italiana : 1989) 20040101

Title: The antidiabetic agent, gliclazide, reduces high insulin-enhanced neutrophil-transendothelial migration through direct effects on the endothelium.

Journal: Diabetes/metabolism research and reviews 20040101

Title: NIDDM: new once-daily intervention for type 2 diabetes mellitus: Diaprel MR.

Journal: Romanian journal of internal medicine = Revue roumaine de medecine interne 20040101

Title: [A prospective randomized study of sulphonylureas therapeutic interchange in patients with type 2 diabetes mellitus].

Journal: Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20040101

Title: Comparison of repaglinide vs. gliclazide in combination with bedtime NPH insulin in patients with Type 2 diabetes inadequately controlled with oral hypoglycaemic agents.

Journal: Diabetic medicine : a journal of the British Diabetic Association 20031101

Title: Genetic cause of hyperglycaemia and response to treatment in diabetes.

Journal: Lancet (London, England) 20031018

Title: Effect of rifampin on the pharmacokinetics and pharmacodynamics of gliclazide.

Journal: Clinical pharmacology and therapeutics 20031001

Title: Monotherapy of type 2 diabetes with once-daily gliclazide modified release in primary care.

Journal: Diabetes research and clinical practice 20031001

Title: [Medication of the month. Gliclazide modified release (Uni Diamicron)].

Journal: Revue medicale de Liege 20031001

Title: Reflex epilepsy and non-ketotic hyperglycemia.

Journal: Epileptic disorders : international epilepsy journal with videotape 20030901

Title: Benefits of gliclazide in the atherosclerotic process: decrease in monocyte adhesion to endothelial cells.

Journal: Metabolism: clinical and experimental 20030801

Title: Gliclazide modified release: A critical review of pharmacodynamic, metabolic, and vasoprotective effects.

Journal: Metabolism: clinical and experimental 20030801

Title: Bioequivalence study of generic gliclazide and Diamicron formulations in healthy Thai male volunteers.

Journal: International journal of clinical pharmacology and therapeutics 20030701

Title: The application of the convective diffusion model and the film equilibrium model to surfactant-facilitated dissolution of gliclazide.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20030701

Title: Pharmacokinetic and pharmacodynamic characterization of gliclazide in healthy volunteers.

Journal: Archives of pharmacal research 20030701

Title: Functional involvement of sulphonylurea receptor (SUR) type 1 and 2B in the activity of pig urethral ATP-sensitive K+ channels.

Journal: British journal of pharmacology 20030601

Title: Comparison of the micro- and macro-vascular effects of glimepiride and gliclazide in metformin-treated patients with Type 2 diabetes: a double-blind, crossover study.

Journal: British journal of clinical pharmacology 20030601

Title: Diabetes and vascular disease: a new international trial.

Journal: Asian cardiovascular & thoracic annals 20030601

Title: Urinary PC-1 and N-acetyl-beta-D-glucosaminidase activity in patients with type 2 diabetes treated with metformin, gliclazide or glibenclamide.

Journal: Annals of clinical biochemistry 20030501

Title: Study of the solubilization of gliclazide by aqueous micellar solutions.

Journal: Journal of pharmaceutical sciences 20030401

Title: Gliclazide protects pancreatic beta-cells from damage by hydrogen peroxide.

Journal: Biochemical and biophysical research communications 20030328

Title: A simple and sensitive HPLC method for determination of gliclazide in human serum.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030305

Title: Population PKPD modelling of the long-term hypoglycaemic effect of gliclazide given as a once-a-day modified release (MR) formulation.

Journal: British journal of clinical pharmacology 20030201

Title: Differential effects of sulphonylureas on the vasodilatory response evoked by K(ATP) channel openers.

Journal: Fundamental & clinical pharmacology 20030201

Title: Diabetes mellitus and weight control: differences of respiratory quotient in type 2 diabetic obese subjects receiving sulfonylureas and non-diabetic obese controls.

Journal: Nutrition (Burbank, Los Angeles County, Calif.) 20030201

Title: Severe relapsing sulphonylurea-induced hypoglycaemia: a diagnostic and therapeutic challenge.

Journal: Postgraduate medical journal 20030201

Title: The mechanisms of inhibitory actions of gliclazide on neutrophils-endothelial cells adhesion and surface expression of endothelial adhesion molecules mediated by a high glucose concentration.

Journal: Journal of diabetes and its complications 20030101

Title: Effects of inhibition of ATP-sensitive potassium channels on metabolic vasodilation in the human forearm.

Journal: Clinical science (London, England : 1979) 20030101

Title: Effects of sulfonylureas on K(ATP) channel-dependent vasodilation.

Journal: Journal of diabetes and its complications 20030101

Title: Monocyte adhesion in diabetic angiopathy: effects of free-radical scavenging.

Journal: Journal of diabetes and its complications 20030101

Title: Diabetic endothelial dysfunction: effect of free radical scavenging in Type 2 diabetic patients.

Journal: Journal of diabetes and its complications 20030101

Title: Spectrofluorimetric and spectrophotometric determination of gliclazide in pharmaceuticals by derivatization with 4-chloro-7-nitrobenzo-2-oxa-1,3-diazole.

Journal: Journal of AOAC International 20030101

Title: Addition of rosiglitazone to existing sulfonylurea treatment in chinese patients with type 2 diabetes and exposure to hepatitis B or C.

Journal: Diabetes technology & therapeutics 20030101

Title: Gliclazide increases insulin receptor tyrosine phosphorylation but not p38 phosphorylation in insulin-resistant skeletal muscle cells.

Journal: The Journal of experimental biology 20021201

Title: Interaction of the cytosolic domains of the Kir6.2 subunit of the K(ATP) channel is modulated by sulfonylureas.

Journal: Diabetes 20021201

Title: Gliclazide directly inhibits arginine-induced glucagon release.

Journal: Diabetes 20021201

Title: Combination therapy of alpha-glucosidase inhibitor and a sulfonylurea compound prolongs the duration of good glycemic control.

Journal: Metabolism: clinical and experimental 20021201

Title: Hypoglycaemic activity of Alpinia galanga rhizome and its extracts in rabbits.

Journal: Fitoterapia 20021201

Title: Eudragit NE30D based metformin/gliclazide extended release tablets: formulation, characterisation and in vitro release studies.

Journal: Chemical & pharmaceutical bulletin 20021101

Title: Effect of gliclazide on islet transplants.

Journal: Transplantation proceedings 20021101

Title: Remodelling of zero-stress state of small intestine in streptozotocin-induced diabetic rats. Effect of gliclazide.

Journal: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20021001

Title: Gliclazide improves anti-oxidant status and nitric oxide-mediated vasodilation in Type 2 diabetes.

Journal: Diabetic medicine : a journal of the British Diabetic Association 20020901

Title: A novel simple method for the investigation of drug binding to the K(ATP) channel sulfonylurea receptor.

Journal: Analytical biochemistry 20020815

Title: Bioequivalence evaluation of two brands of gliclazide 80 mg tablets (Glyzide & Diamicron)--in healthy human volunteers.

Journal: Biopharmaceutics & drug disposition 20020701

Title: Oral hypoglycaemic agent failure.

Journal: Journal of the Indian Medical Association 20020701

Title: Acute gliclazide administration enhances glucose and ketone body utilization in the perfused hind limb of normal and streptozotocin-diabetic rats.

Journal: Life sciences 20020628

Title: Effect of pioglitazone on blood proinsulin levels in patients with type 2 diabetes mellitus.

Journal: Endocrine journal 20020601

Title: Complete bioavailability and lack of food-effect on pharmacokinetics of gliclazide 30 mg modified release in healthy volunteers.

Journal: Biopharmaceutics & drug disposition 20020501

Title: Gliclazide-induced acute hepatitis with hypersensitivity features.

Journal: Digestive diseases and sciences 20020501

Title: Effective and selective prevention of retinal leukostasis in streptozotocin-induced diabetic rats using gliclazide.

Journal: Diabetologia 20020501

Title: Studies on solubility and hypoglycemic activity of gliclazide beta-cyclodextrin-hydroxypropylmethylcellulose complexes.

Journal: Die Pharmazie 20020301

Title: Does gliclazide stimulate first-phase, second-phase, or both phases of insulin release?

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20020201

Title: Gliclazide modified release.

Journal: Drugs 20020101

Title: Advanced glycation end products increase, through a protein kinase C-dependent pathway, vascular endothelial growth factor expression in retinal endothelial cells. Inhibitory effect of gliclazide.

Journal: Journal of diabetes and its complications 20020101

Title: Effect of ethanolic extract of Embelia ribes on dyslipidemia in diabetic rats.

Journal: International journal of experimental diabetes research 20020101

Title: Regulation of glucose transporter 1 expression by gliclazide in rat L6 myoblasts.

Journal: Diabetes, nutrition & metabolism 20011201

Title: Increments in insulin sensitivity during intensive treatment are closely correlated with decrements in glucocorticoid receptor mRNA in skeletal muscle from patients with Type II diabetes.

Journal: Clinical science (London, England : 1979) 20011101

Title: Possible interaction between gliclazide, fluconazole and sulfamethoxazole resulting in severe hypoglycaemia.

Journal: British journal of clinical pharmacology 20011001

Title: Study rationale and design of ADVANCE: action in diabetes and vascular disease--preterax and diamicron MR controlled evaluation.

Journal: Diabetologia 20010901

Title: Acute and short-term administration of a sulfonylurea (gliclazide) increases pulsatile insulin secretion in type 2 diabetes.

Journal: Diabetes 20010801

Title: Gliclazide produces high-affinity block of KATP channels in mouse isolated pancreatic beta cells but not rat heart or arterial smooth muscle cells.

Journal: Diabetologia 20010801

Title: Glibenclamide vs gliclazide in reducing oxidative stress in patients of noninsulin dependent diabetes mellitus--a double blind randomized study.

Journal: The Journal of the Association of Physicians of India 20010801

Title: Gliclazide decreases vascular smooth muscle cell dysfunction induced by cell-mediated oxidized low-density lipoprotein.

Journal: Metabolism: clinical and experimental 20010601

Title: Gliclazide mainly affects insulin secretion in second phase of type 2 diabetes mellitus.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20010601

Title: ATP-Sensitive potassium channels modulate glucose transport in cultured human skeletal muscle cells.

Journal: Endocrine journal 20010601

Title: [Effects of gliclazide on blood rheology of diabetes Wistar rat].

Journal: Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao 20010601

Title: Characteristics of pancreatic beta-cell secretion in Type 2 diabetic patients treated with gliclazide and glibenclamide.

Journal: Diabetes research and clinical practice 20010501

Title: ION-pair liquid chromatography technique for the estimation of metformin in its multicomponent dosage forms.

Journal: Journal of pharmaceutical and biomedical analysis 20010401

Title: Sulfonylurea treatment of type 2 diabetic patients does not reduce the vasodilator response to ischemia.

Journal: Diabetes care 20010401

Title: 24-hour glycemic profile in type 2 diabetic patients treated with gliclazide modified release once daily.

Journal: Diabetes & metabolism 20010401

Title: Effect of KAD-1229, a nonsulfonylurea hypoglycemic agent, on plasma glucose and insulin in streptozotocin-induced diabetic dogs.

Journal: Pharmacology 20010201

Title: Gliclazide and bedtime insulin are more efficient than insulin alone for type 2 diabetic patients with sulfonylurea secondary failure.

Journal: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20010101

Title: Comparison of acarbose and gliclazide as first-line agents in patients with type 2 diabetes.

Journal: Current medical research and opinion 20010101

Title: [Free radical scavenging activity of sulfonylureas: a clinical assessment of the effectiveness of gliclazide].

Journal: Terapevticheskii arkhiv 20010101

Title: Gliclazide-induced hepatitis, hemiplegia and dysphasia in a suicide attempt.

Journal: Journal of pediatric endocrinology & metabolism : JPEM 20010101

Title: [Toxicological analysis in the dawn of the third millenium].

Journal: Annales de biologie clinique 20010101

Title: [Recurrent toxic severe hypoglycemias].

Journal: Annales de biologie clinique 20010101

Title: Determination of gliclazide in pharmaceutical preparations by capillary gas chromatography with cool on-column injection and elimination of the matrix effect.

Journal: Journal of AOAC International 20010101

Title: [Antioxidant and anti-AGE therapeutics: evaluation and perspectives].

Journal: Journal de la Societe de biologie 20010101

Title: Gliclazide-induced acute hepatitis.

Journal: European journal of gastroenterology & hepatology 20000101

Title: Cardiovascular effects of conventional sulfonylureas and glimepiride.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 19960901

Title: Possible gliclazide-induced water retention with azotemia.

Journal: Internal medicine (Tokyo, Japan) 19940301

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Tags:67747-01-7 Molecular Formula|67747-01-7 MDL|67747-01-7 SMILES|67747-01-7 N-(2-(2,4,6-Trichlorophenoxy)ethyl)propan-1-amine