+1 858-523-8231
Login | Register
AA Blocks, Building Blocks, Catalysts, Inhibitors
Login | Register
Home Amines 6779-87-9
6779-87-9,MFCD07375453
Catalog No.:AA005PN2

6779-87-9 | 1-(2-Amino-4-hydroxy-7,8-dihydropteridin-7-yl)propane-1,2-diol

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
≥97%
in stock  
$65.00   $45.00
- +
10mg
≥97%
in stock  
$103.00   $72.00
- +
50mg
≥97%
in stock  
$472.00   $330.00
- +
100mg
≥97%
in stock  
$878.00   $614.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA005PN2
Chemical Name:
1-(2-Amino-4-hydroxy-7,8-dihydropteridin-7-yl)propane-1,2-diol
CAS Number:
6779-87-9
Molecular Formula:
C9H13N5O3
Molecular Weight:
239.2312
MDL Number:
MFCD07375453
SMILES:
CC(C(C1C=Nc2c(N1)nc(nc2O)N)O)O
Properties
Properties
 
Form:
Solid  
MP:
>300℃ (dec.)  
Storage:
Keep in dry area;-20 ℃;  

Computed Properties
 
Complexity:
454  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Heavy Atom Count:
17  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
5  
Rotatable Bond Count:
2  
XLogP3:
-2.2  

Downstream Synthesis Route

[1]Matsuura,Sadao;Murata,Shizuaki;Sugimoto,Takashi[TetrahedronLetters,1986,vol.27,#5,p.585-588]

[2]Matsuura,Sadao;Murata,Shizuaki;Sugimoto,Takashi[TetrahedronLetters,1986,vol.27,#5,p.585-588]

[1]LauraDántola;Schuler,TobiasM.;PaulaDenofrio;Vignoni,Mariana;Capparelli,AlbertoL.;Lorente,Carolina;Thomas,AndrésH.[Tetrahedron,2008,vol.64,#37,p.8692-8699]

[1]Locationinpatent:bodytextDantola,M.Laura;Vignoni,Mariana;Capparelli,AlbertoL.;Lorente,Carolina;Thomas,AndresH.[HelveticaChimicaActa,2008,vol.91,#3,p.411-425]

22150-76-1   
(6R)-5,6,7,8-tetrahydrobiopterindihydrochloride 
  6779-87-9 

[1]CurrentPatentAssignee:BIOMARINPHARMACEUTICALINC-US2009/198055,2009,A1Locationinpatent:Page/Pagecolumn11-12

[2]CurrentPatentAssignee:BIOMARINPHARMACEUTICALINC-US2009/198055,2009,A1Locationinpatent:Page/Pagecolumn12

[1]Locationinpatent:experimentalpartVignoni,Mariana;Cabrerizo,FrancoM.;Lorente,Carolina;Claparols,Catherine;Oliveros,Esther;Thomas,AndresH.[OrganicandBiomolecularChemistry,2010,vol.8,#4,p.800-810]

Literature

Title: Erythropoietin prevents endothelial dysfunction in GTP-cyclohydrolase I-deficient hph1 mice.

Journal: Journal of cardiovascular pharmacology 20141201

Title: Erythropoietin increases bioavailability of tetrahydrobiopterin and protects cerebral microvasculature against oxidative stress induced by eNOS uncoupling.

Journal: Journal of neurochemistry 20141101

Title: Activation of PPARδ prevents endothelial dysfunction induced by overexpression of amyloid-β precursor protein.

Journal: Cardiovascular research 20121201

Title: Quantitative regulation of intracellular endothelial nitric-oxide synthase (eNOS) coupling by both tetrahydrobiopterin-eNOS stoichiometry and biopterin redox status: insights from cells with tet-regulated GTP cyclohydrolase I expression.

Journal: The Journal of biological chemistry 20090109

Title: A vibrational structure of 7,8-dihydrobiopterin bound to dihydroneopterin aldolase.

Journal: The Journal of biological chemistry 20000929

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Related Products of 6779-87-9
Building Blocks
More >
Tags:6779-87-9 Molecular Formula|6779-87-9 MDL|6779-87-9 SMILES|6779-87-9 1-(2-Amino-4-hydroxy-7,8-dihydropteridin-7-yl)propane-1,2-diol