685827-70-7,MFCD06796180
Catalog No.:AA00FAP7

685827-70-7 | 1-Pyridin-2-yl-piperidine-4-carboxylic acid

Pack Size
Purity
Availability
Price(USD)
Quantity
  
100mg
95%
in stock  
$40.00   $28.00
- +
250mg
95%
in stock  
$67.00   $47.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00FAP7
Chemical Name:
1-Pyridin-2-yl-piperidine-4-carboxylic acid
CAS Number:
685827-70-7
Molecular Formula:
C11H14N2O2
Molecular Weight:
206.2411
MDL Number:
MFCD06796180
SMILES:
OC(=O)C1CCN(CC1)c1ccccn1
Properties
Computed Properties
 
Complexity:
225  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
15  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0  
Rotatable Bond Count:
2  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
1.3  

Downstream Synthesis Route
685827-70-7   
1-(pyridin-2-yl)piperidine-4-carbonylchloride 

[1]CurrentPatentAssignee:PFIZERINC-WO2005/79808,2005,A1Locationinpatent:Page/Pagecolumn36;38

[2]CurrentPatentAssignee:PFIZERINC-WO2005/79808,2005,A1Locationinpatent:Page/Pagecolumn37-38

[3]CurrentPatentAssignee:PFIZERINC-WO2004/37809,2004,A1Locationinpatent:Page34-35

[4]Johnson,PatrickS.;Ryckmans,Thomas;Bryans,Justin;Beal,DaveM.;Dack,KevinN.;Feeder,Neil;Harrison,Anthony;Lewis,Mark;Mason,HelenJ.;Mills,James;Newman,Julie;Pasquinet,Christelle;Rawson,DaveJ.;Roberts,LeeR.;Russell,Rachel;Spark,Deborah;Stobie,Alan;Underwood,TobyJ.;Ward,Robin;Wheeler,Simon[BioorganicandMedicinalChemistryLetters,2011,vol.21,#19,p.5684-5687]

[5]CurrentPatentAssignee:DAIICHISANKYOCOMPANY,LIMITED-EP2862861,2015,A1Locationinpatent:Paragraph0144;0145

[6]CurrentPatentAssignee:DAIICHISANKYOCOMPANY,LIMITED-JP2015/113323,2015,ALocationinpatent:Paragraph0105-0107

[7]Harris,PhilipA.;Faucher,Nicolas;George,Nicolas;Eidam,PatrickM.;King,BryanW.;White,GemmaV.;Anderson,NiallA.;Bandyopadhyay,Deepak;Beal,AllisonM.;Beneton,Veronique;Berger,ScottB.;Campobasso,Nino;Campos,Sebastien;Capriotti,CarolA.;Cox,JulieA.;Daugan,Alain;Donche,Frederic;Fouchet,Marie-Hélène;Finger,JoshuaN.;Geddes,Brad;Gough,PeterJ.;Grondin,Pascal;Hoffman,BonnieL.;Hoffman,SandraJ.;Hutchinson,SusanE.;Jeong,JaeU.;Jigorel,Emilie;Lamoureux,Pauline;Leister,LaraK.;Lich,JohnD.;Mahajan,MukeshK.;Meslamani,Jamel;Mosley,JulieE.;Nagilla,Rakesh;Nassau,PamelaM.;Ng,Sze-Ling;Ouellette,MichaelT.;Pasikanti,KishoreK.;Potvain,Florent;Reilly,MichaelA.;Rivera,ElizabethJ.;Sautet,Stéphane;Schaeffer,MichelleC.;Sehon,ClarkA.;Sun,Helen;Thorpe,JamesH.;Totoritis,RachelD.;Ward,Paris;Wellaway,Natalie;Wisnoski,DavidD.;Woolven,JamesM.;Bertin,John;Marquis,RobertW.[JournalofMedicinalChemistry,2019,vol.62,#10,p.5096-5110]

[1]CurrentPatentAssignee:C4THERAPEUTICSINC-WO2020/210630,2020,A1Locationinpatent:Page/Pagecolumn643-644

[2]CurrentPatentAssignee:PFIZERINC-WO2004/37809,2004,A1Locationinpatent:Page31

[3]Lu,Tianbao;Connolly,PeterJ.;Philippar,Ulrike;Sun,Weimei;Cummings,MaxwellD.;Barbay,Kent;Gys,Luc;VanNuffel,Luc;Austin,Nigel;Bekkers,Mariette;Shen,Fang;Cai,Ann;Attar,Ricardo;Meerpoel,Lieven;Edwards,James[BioorganicandMedicinalChemistryLetters,2019,vol.29,#23]

[1]CurrentPatentAssignee:PFIZERINC-WO2005/79808,2005,A1Locationinpatent:Page/Pagecolumn36

[2]Johnson,PatrickS.;Ryckmans,Thomas;Bryans,Justin;Beal,DaveM.;Dack,KevinN.;Feeder,Neil;Harrison,Anthony;Lewis,Mark;Mason,HelenJ.;Mills,James;Newman,Julie;Pasquinet,Christelle;Rawson,DaveJ.;Roberts,LeeR.;Russell,Rachel;Spark,Deborah;Stobie,Alan;Underwood,TobyJ.;Ward,Robin;Wheeler,Simon[BioorganicandMedicinalChemistryLetters,2011,vol.21,#19,p.5684-5687]

[3]DeCandia,Modesto;Fiorella,Filomena;Lopopolo,Gianfranco;Carotti,Andrea;Romano,MariaRosaria;Lograno,MarcelloDiego;Martel,Sophie;Carrupt,Pierre-Alain;Belviso,BennyD.;Caliandro,Rocco;Altomare,Cosimo[JournalofMedicinalChemistry,2013,vol.56,#21,p.8696-8711]

685827-70-7   
4-(4-benzyl-5-methyl-4H-1,2,4triazol-3-yl)-3,4,5,6-tetrahydro-2H-1,2'bipyridinyl 

[1]Johnson,PatrickS.;Ryckmans,Thomas;Bryans,Justin;Beal,DaveM.;Dack,KevinN.;Feeder,Neil;Harrison,Anthony;Lewis,Mark;Mason,HelenJ.;Mills,James;Newman,Julie;Pasquinet,Christelle;Rawson,DaveJ.;Roberts,LeeR.;Russell,Rachel;Spark,Deborah;Stobie,Alan;Underwood,TobyJ.;Ward,Robin;Wheeler,Simon[BioorganicandMedicinalChemistryLetters,2011,vol.21,#19,p.5684-5687]

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Tags:685827-70-7 Molecular Formula|685827-70-7 MDL|685827-70-7 SMILES|685827-70-7 1-Pyridin-2-yl-piperidine-4-carboxylic acid
Catalog No.: AA00FAP7
685827-70-7,MFCD06796180
685827-70-7 | 1-Pyridin-2-yl-piperidine-4-carboxylic acid
Pack Size: 100mg
Purity: 95%
in stock
$40.00 $28.00
Pack Size: 250mg
Purity: 95%
in stock
$67.00 $47.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA00FAP7
Chemical Name: 1-Pyridin-2-yl-piperidine-4-carboxylic acid
CAS Number: 685827-70-7
Molecular Formula: C11H14N2O2
Molecular Weight: 206.2411
MDL Number: MFCD06796180
SMILES: OC(=O)C1CCN(CC1)c1ccccn1
Properties
Complexity: 225  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 15  
Hydrogen Bond Acceptor Count: 4  
Hydrogen Bond Donor Count: 1  
Isotope Atom Count: 0  
Rotatable Bond Count: 2  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 1.3  
Downstream Synthesis Route
685827-70-7   
1-(pyridin-2-yl)piperidine-4-carbonylchloride 

[1]CurrentPatentAssignee:PFIZERINC-WO2005/79808,2005,A1Locationinpatent:Page/Pagecolumn36;38

[2]CurrentPatentAssignee:PFIZERINC-WO2005/79808,2005,A1Locationinpatent:Page/Pagecolumn37-38

[3]CurrentPatentAssignee:PFIZERINC-WO2004/37809,2004,A1Locationinpatent:Page34-35

[4]Johnson,PatrickS.;Ryckmans,Thomas;Bryans,Justin;Beal,DaveM.;Dack,KevinN.;Feeder,Neil;Harrison,Anthony;Lewis,Mark;Mason,HelenJ.;Mills,James;Newman,Julie;Pasquinet,Christelle;Rawson,DaveJ.;Roberts,LeeR.;Russell,Rachel;Spark,Deborah;Stobie,Alan;Underwood,TobyJ.;Ward,Robin;Wheeler,Simon[BioorganicandMedicinalChemistryLetters,2011,vol.21,#19,p.5684-5687]

[5]CurrentPatentAssignee:DAIICHISANKYOCOMPANY,LIMITED-EP2862861,2015,A1Locationinpatent:Paragraph0144;0145

[6]CurrentPatentAssignee:DAIICHISANKYOCOMPANY,LIMITED-JP2015/113323,2015,ALocationinpatent:Paragraph0105-0107

[7]Harris,PhilipA.;Faucher,Nicolas;George,Nicolas;Eidam,PatrickM.;King,BryanW.;White,GemmaV.;Anderson,NiallA.;Bandyopadhyay,Deepak;Beal,AllisonM.;Beneton,Veronique;Berger,ScottB.;Campobasso,Nino;Campos,Sebastien;Capriotti,CarolA.;Cox,JulieA.;Daugan,Alain;Donche,Frederic;Fouchet,Marie-Hélène;Finger,JoshuaN.;Geddes,Brad;Gough,PeterJ.;Grondin,Pascal;Hoffman,BonnieL.;Hoffman,SandraJ.;Hutchinson,SusanE.;Jeong,JaeU.;Jigorel,Emilie;Lamoureux,Pauline;Leister,LaraK.;Lich,JohnD.;Mahajan,MukeshK.;Meslamani,Jamel;Mosley,JulieE.;Nagilla,Rakesh;Nassau,PamelaM.;Ng,Sze-Ling;Ouellette,MichaelT.;Pasikanti,KishoreK.;Potvain,Florent;Reilly,MichaelA.;Rivera,ElizabethJ.;Sautet,Stéphane;Schaeffer,MichelleC.;Sehon,ClarkA.;Sun,Helen;Thorpe,JamesH.;Totoritis,RachelD.;Ward,Paris;Wellaway,Natalie;Wisnoski,DavidD.;Woolven,JamesM.;Bertin,John;Marquis,RobertW.[JournalofMedicinalChemistry,2019,vol.62,#10,p.5096-5110]

1250595-15-3    685827-70-7 

[1]CurrentPatentAssignee:C4THERAPEUTICSINC-WO2020/210630,2020,A1Locationinpatent:Page/Pagecolumn643-644

[2]CurrentPatentAssignee:PFIZERINC-WO2004/37809,2004,A1Locationinpatent:Page31

[3]Lu,Tianbao;Connolly,PeterJ.;Philippar,Ulrike;Sun,Weimei;Cummings,MaxwellD.;Barbay,Kent;Gys,Luc;VanNuffel,Luc;Austin,Nigel;Bekkers,Mariette;Shen,Fang;Cai,Ann;Attar,Ricardo;Meerpoel,Lieven;Edwards,James[BioorganicandMedicinalChemistryLetters,2019,vol.29,#23]

154348-19-3    685827-70-7 

[1]CurrentPatentAssignee:PFIZERINC-WO2005/79808,2005,A1Locationinpatent:Page/Pagecolumn36

[2]Johnson,PatrickS.;Ryckmans,Thomas;Bryans,Justin;Beal,DaveM.;Dack,KevinN.;Feeder,Neil;Harrison,Anthony;Lewis,Mark;Mason,HelenJ.;Mills,James;Newman,Julie;Pasquinet,Christelle;Rawson,DaveJ.;Roberts,LeeR.;Russell,Rachel;Spark,Deborah;Stobie,Alan;Underwood,TobyJ.;Ward,Robin;Wheeler,Simon[BioorganicandMedicinalChemistryLetters,2011,vol.21,#19,p.5684-5687]

[3]DeCandia,Modesto;Fiorella,Filomena;Lopopolo,Gianfranco;Carotti,Andrea;Romano,MariaRosaria;Lograno,MarcelloDiego;Martel,Sophie;Carrupt,Pierre-Alain;Belviso,BennyD.;Caliandro,Rocco;Altomare,Cosimo[JournalofMedicinalChemistry,2013,vol.56,#21,p.8696-8711]

685827-70-7   
4-(4-benzyl-5-methyl-4H-1,2,4triazol-3-yl)-3,4,5,6-tetrahydro-2H-1,2'bipyridinyl 

[1]Johnson,PatrickS.;Ryckmans,Thomas;Bryans,Justin;Beal,DaveM.;Dack,KevinN.;Feeder,Neil;Harrison,Anthony;Lewis,Mark;Mason,HelenJ.;Mills,James;Newman,Julie;Pasquinet,Christelle;Rawson,DaveJ.;Roberts,LeeR.;Russell,Rachel;Spark,Deborah;Stobie,Alan;Underwood,TobyJ.;Ward,Robin;Wheeler,Simon[BioorganicandMedicinalChemistryLetters,2011,vol.21,#19,p.5684-5687]

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