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68745-38-0,MFCD00017482
Catalog No.:AA01CC5I

68745-38-0 | Pinocembrin

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1mg
98%
in stock  
$124.00   $87.00
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5mg
98%
in stock  
$222.00   $155.00
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10mg
98%
in stock  
$325.00   $228.00
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25mg
98%
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$515.00   $360.00
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250mg
98%
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$1,304.00   $913.00
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5g
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$7,115.00   $4,980.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01CC5I
Chemical Name:
Pinocembrin
CAS Number:
68745-38-0
Molecular Formula:
C15H12O4
Molecular Weight:
256.2534
MDL Number:
MFCD00017482
SMILES:
Oc1cc2OC(CC(=O)c2c(c1)O)c1ccccc1
Properties
Computed Properties
 
Complexity:
337  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
19  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
1  
Undefined Atom Stereocenter Count:
1  
XLogP3:
2.7  

Literature

Title: Honey constituents up-regulate detoxification and immunity genes in the western honey bee Apis mellifera.

Journal: Proceedings of the National Academy of Sciences of the United States of America 20130528

Title: In vitro and in vivo protection provided by pinocembrin against lipopolysaccharide-induced inflammatory responses.

Journal: International immunopharmacology 20120901

Title: Phytochemical and antimicrobial investigations of stilbenoids and flavonoids isolated from three species of Combretaceae.

Journal: Fitoterapia 20120701

Title: A prenylated flavanone from Dalea elegans inhibits rhodamine 6 G efflux and reverses fluconazole-resistance in Candida albicans.

Journal: Planta medica 20120601

Title: Compounds of Alpinia katsumadai as potential efflux inhibitors in Mycobacterium smegmatis.

Journal: Bioorganic & medicinal chemistry 20120415

Title: Alpinia katsumadai H(AYATA) seed extract inhibit LPS-induced inflammation by induction of heme oxygenase-1 in RAW264.7 cells.

Journal: Inflammation 20120401

Title: Anti-inflammatory flavonoids from Cryptocarya chingii.

Journal: Phytochemistry 20120401

Title: In vitro activity of the F-6 fraction of oregano against Giardia intestinalis.

Journal: Parasitology 20120401

Title: Computational prediction of metabolism: sites, products, SAR, P450 enzyme dynamics, and mechanisms.

Journal: Journal of chemical information and modeling 20120326

Title: Induction of oxidative DNA damage by flavonoids of propolis: its mechanism and implication about antioxidant capacity.

Journal: Chemical research in toxicology 20120113

Title: ¹H-NMR simultaneous identification of health-relevant compounds in propolis extracts.

Journal: Phytochemical analysis : PCA 20120101

Title: Secondary metabolites isolated from Piper chimonantifolium and their antifungal activity.

Journal: Natural product research 20120101

Title: Methylenebissantin: a rare methylene-bridged bisflavonoid from Dodonaea viscosa which inhibits Plasmodium falciparum enoyl-ACP reductase.

Journal: Bioorganic & medicinal chemistry letters 20120101

Title: Synthesis and antidiabetic activity of 5,7-dihydroxyflavonoids and analogs.

Journal: Chemistry & biodiversity 20120101

Title: Uptake characteristics of pinocembrin and its effect on p-glycoprotein at the blood-brain barrier in in vitro cell experiments.

Journal: Journal of Asian natural products research 20120101

Title: De novo transcriptome of safflower and the identification of putative genes for oleosin and the biosynthesis of flavonoids.

Journal: PloS one 20120101

Title: Propolis standardized extract (EPP-AF®), an innovative chemically and biologically reproducible pharmaceutical compound for treating wounds.

Journal: International journal of biological sciences 20120101

Title: Physical and functional interaction of NCX1 and EAAC1 transporters leading to glutamate-enhanced ATP production in brain mitochondria.

Journal: PloS one 20120101

Title: Effects of pinocembrin on the initiation and promotion stages of rat hepatocarcinogenesis.

Journal: Asian Pacific journal of cancer prevention : APJCP 20120101

Title: Localization of oleuropeyl glucose esters and a flavanone to secretory cavities of Myrtaceae.

Journal: PloS one 20120101

Title: Chemical compositions and antioxidant activities of water extracts of Chinese propolis.

Journal: Journal of agricultural and food chemistry 20111214

Title: Alkylated flavanones from the bark of Cryptocarya chartacea as dengue virus NS5 polymerase inhibitors.

Journal: Journal of natural products 20111128

Title: Hybrid flavan-chalcones, aromatase and lipoxygenase inhibitors, from Desmos cochinchinensis.

Journal: Phytochemistry 20111101

Title: New flavanones from the leaves of Cryptocarya chinensis and their antituberculosis activity.

Journal: Chemistry & biodiversity 20111101

Title: Bioassay-guided isolation of constituents of Piper sarmentosum using a mitochondrial transmembrane potential assay.

Journal: Journal of natural products 20111028

Title: Flavonoids in Scutellaria immaculata and S. ramosissima (Lamiaceae) and their biological activity.

Journal: The Journal of pharmacy and pharmacology 20111001

Title: Cardamonin suppresses nitric oxide production via blocking the IFN-γ/STAT pathway in endotoxin-challenged peritoneal macrophages of ICR mice.

Journal: Life sciences 20110829

Title: Natural products in caries research: current (limited) knowledge, challenges and future perspective.

Journal: Caries research 20110701

Title: Chemical composition of the ethanolic propolis extracts and its effect on HeLa cells.

Journal: Journal of ethnopharmacology 20110601

Title: [Effect of pinocembrin on brain mitochondrial respiratory function].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20110601

Title: Pinocembrin attenuates blood-brain barrier injury induced by global cerebral ischemia-reperfusion in rats.

Journal: Brain research 20110519

Title: The characteristics of therapeutic effect of pinocembrin in transient global brain ischemia/reperfusion rats.

Journal: Life sciences 20110314

Title: Flavonoid Glycosides from the Seeds of Litchi chinensis.

Journal: Journal of agricultural and food chemistry 20110223

Title: Antimicrobial activity of flavonoids from Piper lanceaefolium and other Colombian medicinal plants against antibiotic susceptible and resistant strains of Neisseria gonorrhoeae.

Journal: Sexually transmitted diseases 20110201

Title: Effect of pinocembrin isolated from Boesenbergia pandurata on xenobiotic-metabolizing enzymes in rat liver.

Journal: Drug metabolism letters 20110101

Title: Ethanol extract of chinese propolis facilitates functional recovery of locomotor activity after spinal cord injury.

Journal: Evidence-based complementary and alternative medicine : eCAM 20110101

Title: Honey induces apoptosis in renal cell carcinoma.

Journal: Pharmacognosy magazine 20110101

Title: Clinical Evidence of the Efficacy of a Mouthwash Containing Propolis for the Control of Plaque and Gingivitis: A Phase II Study.

Journal: Evidence-based complementary and alternative medicine : eCAM 20110101

Title: Analytical methods applied to diverse types of Brazilian propolis.

Journal: Chemistry Central journal 20110101

Title: Evaluation of antiaggregatory activity of flavonoid aglycone series.

Journal: Nutrition journal 20110101

Title: Polyphenolic fraction of Algerian propolis protects rat kidney against acute oxidative stress induced by doxorubicin.

Journal: Indian journal of nephrology 20110101

Title: Honey and renal cell carcinoma.

Journal: Pharmacognosy magazine 20110101

Title: Development of non-natural flavanones as antimicrobial agents.

Journal: PloS one 20110101

Title: [Composition, antifungal and radical scavenging activities of 4 propolis].

Journal: Medical mycology journal 20110101

Title: Propolis can potentialise the anti-adhesion activity of proanthocyanidins on uropathogenic Escherichia coli in the prevention of recurrent urinary tract infections.

Journal: BMC research notes 20110101

Title: Bioactive constituents and medicinal importance of genus Alnus.

Journal: Pharmacognosy reviews 20110101

Title: Engineered polyketide biosynthesis and biocatalysis in Escherichia coli.

Journal: Applied microbiology and biotechnology 20101201

Title: Seasonal variation, chemical composition and antioxidant activity of Brazilian propolis samples.

Journal: Evidence-based complementary and alternative medicine : eCAM 20100901

Title: Volatile composition screening of Salix spp. nectar honey: benzenecarboxylic acids, norisoprenoids, terpenes, and others.

Journal: Chemistry & biodiversity 20100901

Title: Response of Epilachna paenulata to two flavonoids, pinocembrin and quercetin, in a comparative study.

Journal: Journal of chemical ecology 20100801

Title: [Qualitative and quantitative methods for Alpiniae Katsumadai semen].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100801

Title: Pinocembrin protects the neurovascular unit by reducing inflammation and extracellular proteolysis in MCAO rats.

Journal: Journal of Asian natural products research 20100501

Title: Phenolic compounds from Cryptocarya konishii: their cytotoxic and tyrosine kinase inhibitory properties.

Journal: Journal of natural medicines 20100401

Title: Terpenes and flavonoids from an Egyptian collection of Cleome droserifolia.

Journal: Natural product research 20100401

Title: Biogenic synthesis of Au and Ag nanoparticles by Indian propolis and its constituents.

Journal: Colloids and surfaces. B, Biointerfaces 20100301

Title: Anticancer effects of Alpinia pricei Hayata roots.

Journal: Journal of agricultural and food chemistry 20100224

Title: Chemical constituents of red Mexican propolis.

Journal: Journal of agricultural and food chemistry 20100224

Title: Argentinean propolis from Zuccagnia punctata Cav. (Caesalpinieae) exudates: phytochemical characterization and antifungal activity.

Journal: Journal of agricultural and food chemistry 20100113

Title: Antiviral activity and mode of action of propolis extracts and selected compounds.

Journal: Phytotherapy research : PTR 20100101

Title: Antibacterial mono- and sesquiterpene esters of benzoic acids from Iranian propolis.

Journal: Chemistry Central journal 20100101

Title: Antiproliferative effect of Tualang honey on oral squamous cell carcinoma and osteosarcoma cell lines.

Journal: BMC complementary and alternative medicine 20100101

Title: Antimutagenicity and antiproliferative studies of lipidic extracts from white shrimp (Litopenaeus vannamei).

Journal: Marine drugs 20100101

Title: Bridging the gap between fluxomics and industrial biotechnology.

Journal: Journal of biomedicine & biotechnology 20100101

Title: Two new sesquiterpene glucosides from Dennstaedtia scabra (Wall.) Moore.

Journal: Chemical & pharmaceutical bulletin 20091001

Title: Modeling of the aryl hydrocarbon receptor (AhR) ligand binding domain and its utility in virtual ligand screening to predict new AhR ligands.

Journal: Journal of medicinal chemistry 20090924

Title: Anti-inflammatory effects of the roots of Alpinia pricei Hayata and its phenolic compounds.

Journal: Journal of agricultural and food chemistry 20090909

Title: Development and validation of a high-performance liquid chromatographic method for determination of pinocembrin in rat plasma: application to pharmacokinetic study.

Journal: Journal of pharmaceutical and biomedical analysis 20090712

Title: Antifeedant activity of ethanolic extract from Flourensia oolepis and isolation of pinocembrin as its active principle compound.

Journal: Bioresource technology 20090701

Title: Simultaneous quantification of eight major bioactive phenolic compounds in Chinese propolis by high-performance liquid chromatography.

Journal: Natural product communications 20090601

Title: Engineering of plant-specific phenylpropanoids biosynthesis in Streptomyces venezuelae.

Journal: Journal of biotechnology 20090520

Title: Correlation between antiangiogenic activity and antioxidant activity of various components from propolis.

Journal: Molecular nutrition & food research 20090501

Title: Main flavonoids, DPPH activity, and metal content allow determination of the geographical origin of propolis from the Province of San Juan (Argentina).

Journal: Journal of agricultural and food chemistry 20090408

Title: From functional food to medicinal product: systematic approach in analysis of polyphenolics from propolis and wine.

Journal: Nutrition journal 20090101

Title: Antiproliferative effects of honey and of its polyphenols: a review.

Journal: Journal of biomedicine & biotechnology 20090101

Title: Yeast artificial chromosomes employed for random assembly of biosynthetic pathways and production of diverse compounds in Saccharomyces cerevisiae.

Journal: Microbial cell factories 20090101

Title: Bioactivity of flavonoids isolated from Lychnophora markgravii against Leishmania amazonensis amastigotes.

Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20090101

Title: Bee products prevent VEGF-induced angiogenesis in human umbilical vein endothelial cells.

Journal: BMC complementary and alternative medicine 20090101

Title: Anti-aromatase activity of the constituents from damiana (Turnera diffusa).

Journal: Journal of ethnopharmacology 20081208

Title: Antioxidant and antimicrobial effects of phenolic compounds extracts of Northeast Portugal honey.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20081201

Title: Negative ion 'chip-based' nanospray tandem mass spectrometry for the analysis of flavonoids in glandular trichomes of Lychnophora ericoides Mart. (Asteraceae).

Journal: Rapid communications in mass spectrometry : RCM 20081201

Title: Protective effects of Chinese propolis and its component, chrysin, against neuronal cell death via inhibition of mitochondrial apoptosis pathway in SH-SY5Y cells.

Journal: Journal of agricultural and food chemistry 20081008

Title: Pinocembrin prevents glutamate-induced apoptosis in SH-SY5Y neuronal cells via decrease of bax/bcl-2 ratio.

Journal: European journal of pharmacology 20080904

Title: Chemical composition and botanical origin of red propolis, a new type of brazilian propolis.

Journal: Evidence-based complementary and alternative medicine : eCAM 20080901

Title: Pinocembrin protects rat brain against oxidation and apoptosis induced by ischemia-reperfusion both in vivo and in vitro.

Journal: Brain research 20080624

Title: [Chemical constituents of Oxytropis falcate].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080601

Title: [Studies on chemical constituents of alpinia katsumadai].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20080601

Title: Antimicrobial acylphloroglucinols and dibenzyloxy flavonoids from flowers of Helichrysum gymnocomum.

Journal: Phytochemistry 20080501

Title: NF-kappaB-activated tissue transglutaminase is involved in ethanol-induced hepatic injury and the possible role of propolis in preventing fibrogenesis.

Journal: Toxicology 20080418

Title: Inhibitory effect of compounds from Zingiberaceae species on human platelet aggregation.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20080401

Title: Acute neurovascular unit protective action of pinocembrin against permanent cerebral ischemia in rats.

Journal: Journal of Asian natural products research 20080101

Title: Yeast cell factories for fine chemical and API production.

Journal: Microbial cell factories 20080101

Title: Synthesis and enantiomeric resolution of (+/-)-pinocembrin.

Journal: Journal of Asian natural products research 20080101

Title: Analysis of the polyphenolic fraction of propolis from different sources by liquid chromatography-tandem mass spectrometry.

Journal: Journal of pharmaceutical and biomedical analysis 20071105

Title: Sonoran propolis: chemical composition and antiproliferative activity on cancer cell lines.

Journal: Planta medica 20071101

Title: Effect of mouthrinse containing propolis on oral microorganisms and human gingival fibroblasts.

Journal: European journal of dentistry 20071001

Title: Evaluation of antioxidative activity of Croatian propolis samples using DPPH* and ABTS*+ stable free radical assays.

Journal: Molecules (Basel, Switzerland) 20070515

Title: Endothelium-dependent and -independent relaxation induced by pinocembrin in rat aortic rings.

Journal: Vascular pharmacology 20070301

Title: Pinocembrin triggers Bax-dependent mitochondrial apoptosis in colon cancer cells.

Journal: Molecular carcinogenesis 20070301

Title: Antioxidant compounds of propolis determined by capillary electrophoresis-mass spectrometry.

Journal: Journal of separation science 20070301

Title: Exotic flora dependence of an unusual Brazilian propolis: the pinocembrin biomarker by capillary techniques.

Journal: Journal of pharmaceutical and biomedical analysis 20070104

Title: Optimisation of an extraction procedure and chemical characterisation of Croatian propolis tinctures.

Journal: Phytochemical analysis : PCA 20070101

Title: Different extraction methods of biologically active components from propolis: a preliminary study.

Journal: Chemistry Central journal 20070101

Title: Evaluation of propolis polyphenols absorption in humans by liquid chromatography/tandem mass spectrometry.

Journal: Rapid communications in mass spectrometry : RCM 20070101

Title: Analysis of flavonoids from propolis by on-line HPLC-electrospray mass spectrometry.

Journal: Journal of pharmaceutical and biomedical analysis 20060926

Title: Analysis of antioxidant activities contained in the Boesenbergia pandurata Schult. Rhizome.

Journal: Bioscience, biotechnology, and biochemistry 20060901

Title: Protections of pinocembrin on brain mitochondria contribute to cognitive improvement in chronic cerebral hypoperfused rats.

Journal: European journal of pharmacology 20060807

Title: Propolis from the northwest of Argentina as a source of antifungal principles.

Journal: Journal of applied microbiology 20060701

Title: Combinatorial biosynthesis of flavones and flavonols in Escherichia coli.

Journal: Applied microbiology and biotechnology 20060601

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Biosynthesis of isoprenoids, polyunsaturated fatty acids and flavonoids in Saccharomyces cerevisiae.

Journal: Microbial cell factories 20060101

Title: Efficient production of (2S)-flavanones by Escherichia coli containing an artificial biosynthetic gene cluster.

Journal: Applied microbiology and biotechnology 20050901

Title: Dihydrostilbene derivatives from Glycyrrhiza glabra leaves.

Journal: Journal of natural products 20050701

Title: High-performance liquid chromatographic separation and chiroptical properties of the enantiomers of naringenin and other flavanones.

Journal: Journal of chromatography. A 20050527

Title: [Phytochemical and pharmacological research progress in Leontopodium medicinal plants].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050201

Title: Chemical compositions and antimicrobial activities of four different Anatolian propolis samples.

Journal: Microbiological research 20050101

Title: Vasorelaxing effects of flavonoids: investigation on the possible involvement of potassium channels.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20041001

Title: Electrospray ionization mass spectrometry fingerprinting of propolis.

Journal: The Analyst 20040801

Title: Separation of flavonoids and phenolic acids from propolis by capillary zone electrophoresis.

Journal: Electrophoresis 20040601

Title: Identification of metabolites in plasma and urine of Uruguayan propolis-treated rats.

Journal: Journal of agricultural and food chemistry 20040519

Title: Quantitative high-performance liquid chromatography analyses of flavonoids in Australian Eucalyptus honeys.

Journal: Journal of agricultural and food chemistry 20040128

Title: Validated methods for the quantification of biologically active constituents of poplar-type propolis.

Journal: Phytochemical analysis : PCA 20040101

Title: DPPH free radical scavenger components from the fruits of Alpinia rafflesiana Wall. ex. Bak. (Zingiberaceae).

Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20040101

Title: Analysis of propolis from the continental and Adriatic regions of Croatia.

Journal: Acta pharmaceutica (Zagreb, Croatia) 20031201

Title: Antiprotozoal activity of the constituents of Teloxys graveolens.

Journal: Phytotherapy research : PTR 20030801

Title: New dihydrostilbene derivatives from the leaves of Glycyrrhiza glabra and evaluation of their antioxidant activity.

Journal: Journal of natural products 20030401

Title: Assessment of the anti-inflammatory activity and free radical scavenger activity of tiliroside.

Journal: European journal of pharmacology 20030207

Title: Trypanocidal activity of Lychnophora staavioides Mart. (Vernonieae, Asteraceae).

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20030101

Title: Pinostrobin from honey and Thai ginger (Boesenbergia pandurata): a potent flavonoid inducer of mammalian phase 2 chemoprotective and antioxidant enzymes.

Journal: Journal of agricultural and food chemistry 20021204

Title: The inhibitory effect of propolis and caffeic acid phenethyl ester on cyclooxygenase activity in J774 macrophages.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20020901

Title: Phenolic glycosides from Viscum angulatum.

Journal: Journal of natural products 20020501

Title: Antifungal activity of benzoic acid derivatives from Piper lanceaefolium.

Journal: Journal of natural products 20020101

Title: Anti-inflammatory cyclohexenyl chalcone derivatives in Boesenbergia pandurata.

Journal: Phytochemistry 20020101

Title: Chemical composition of European propolis: expected and unexpected results.

Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20020101

Title: Structural analysis of a novel antimutagenic compound, 4-Hydroxypanduratin A, and the antimutagenic activity of flavonoids in a Thai spice, fingerroot (Boesenbergia pandurata Schult.) against mutagenic heterocyclic amines.

Journal: Journal of agricultural and food chemistry 20010601

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