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69004-04-2,MFCD09263475
Catalog No.:AA005M3K

69004-04-2 | Toltrazuril sulfone

Pack Size
Purity
Availability
Price(USD)
Quantity
  
10mg
≥98%
in stock  
$46.00   $32.00
- +
25mg
95%
in stock  
$54.00   $38.00
- +
100mg
95%
in stock  
$161.00   $113.00
- +
1g
95%
in stock  
$488.00   $342.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA005M3K
Chemical Name:
Toltrazuril sulfone
CAS Number:
69004-04-2
Molecular Formula:
C18H14F3N3O6S
Molecular Weight:
457.3805
MDL Number:
MFCD09263475
SMILES:
Cc1cc(ccc1Oc1ccc(cc1)S(=O)(=O)C(F)(F)F)n1c(=O)[nH]c(=O)n(c1=O)C
Properties
Properties
 
Form:
Solid  
MP:
242-244°C  
Storage:
2-8℃;Keep in dry area;  

Computed Properties
 
Complexity:
836  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
31  
Hydrogen Bond Acceptor Count:
9  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
4  
XLogP3:
3.1  

Literature

Title: Toltrazuril sulfone sodium salt: synthesis, analytical detection, and pharmacokinetics in the horse.

Journal: Journal of veterinary pharmacology and therapeutics 20120601

Title: Keratoconjunctivitis associated with Toxoplasma gondii in a dog.

Journal: Veterinary ophthalmology 20090101

Title: Equine protozoal myeloencephalitis associated with neosporosis in 3 horses.

Journal: Journal of veterinary internal medicine 20070101

Title: Ponazuril inhibits the development of Eimeria vermiformis in experimentally infected outbred Swiss mice.

Journal: Parasitology research 20050201

Title: Effects of toltrazuril and ponazuril on Hammondia heydorni (syn. Neospora caninum) infections in mice.

Journal: Parasitology research 20040401

Title: Effects of toltrazuril and ponazuril on the fine structure and multiplication of tachyzoites of the NC-1 strain of Neospora caninum (a synonym of Hammondia heydorni) in cell cultures.

Journal: Parasitology research 20040401

Title: The production and characterisation of an antibody to detect the coccidiostat toltrazuril and its metabolite ponazuril.

Journal: The Analyst 20030501

Title: Efficacy of toltrazuril and ponazuril against experimental Neospora caninum infection in mice.

Journal: Parasitology research 20010101

Title: Safety of ponazuril 15% oral paste in horses.

Journal: Veterinary therapeutics : research in applied veterinary medicine 20010101

Title: Sheila M Mitchell, et al. The effects of ponazuril on development of apicomplexans in vitro. J Eukaryot Microbiol. May-Jun 2005;52(3):231-5.

Title: Sheila M Mitchell, et al. Efficacy of ponazuril in vitro and in preventing and treating Toxoplasma gondii infections in mice. J Parasitol. 2004 Jun;90(3):639-42.

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