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6921-66-0,MFCD00238557
Catalog No.:AA0033WH

6921-66-0 | 4'-Chloro-2'-hydroxyacetophenone

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1g
98%
in stock  
$21.00   $15.00
- +
5g
98%
in stock  
$39.00   $28.00
- +
10g
98%
in stock  
$48.00   $34.00
- +
25g
98%
in stock  
$111.00   $78.00
- +
100g
98%
in stock  
$441.00   $309.00
- +
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA0033WH
Chemical Name:
4'-Chloro-2'-hydroxyacetophenone
CAS Number:
6921-66-0
Molecular Formula:
C8H7ClO2
Molecular Weight:
170.5930
MDL Number:
MFCD00238557
SMILES:
Clc1ccc(c(c1)O)C(=O)C
Properties
Properties
 
BP:
268.4°C at 760 mmHg  
Form:
Liquid  
MP:
27-30 °C  
Refractive Index:
1.5750 to 1.5790  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
158  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
11  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
1  
XLogP3:
2.6  

Upstream Synthesis Route

[1]EuropeanJournalofMedicinalChemistry,2017,vol.130,p.195-208

[2]Patent:WO2009/62289,2009,A1,

[1]Synthesis,1989,#9,p.709-710

[1]JournalofMedicinalChemistry,2006,vol.49,#22,p.6569-6584

[1]TetrahedronLetters,2017,vol.58,#51,p.4766-4768

[1]AnnalidiChimica(Rome,Italy),1951,vol.41,p.421,423

[2]JournaloftheIndianChemicalSociety,1959,vol.36,p.784

Downstream Synthesis Route

[1]AnnalidiChimica,1951,vol.41,p.421,423

[1]Patent:US6353116,2002,B1.Locationinpatent:Pagecolumn22

[2]Patent:WO2005/75463,2005,A1.Locationinpatent:Page/Pagecolumn40

[3]PharmacyandPharmacologyCommunications,1999,vol.5,p.323-329

[4]JournaloftheIndianChemicalSociety,1952,vol.29,p.419,421,423

[5]JournaloftheIndianChemicalSociety,1952,vol.29,p.419,421,423

[6]JournaloftheChemicalSociety,1958,p.146,149

[7]ChemischeBerichte,1956,vol.89,p.1,10

[8]HelveticaChimicaActa,1963,vol.46,p.727-741

[9]SpectrochimicaActaPartA:MolecularandBiomolecularSpectroscopy,1981,vol.37,p.199-204

[10]BioorganicandMedicinalChemistry,2005,vol.13,p.5996-6001

[11]Patent:US2005/176808,2005,A1.Locationinpatent:Page/Pagecolumn16

[12]Patent:US2005/171149,2005,A1.Locationinpatent:Page/Pagecolumn16

[13]MedChemComm,2013,vol.4,p.1257-1266

[14]MedicinalChemistry,2020,vol.16,p.212-228

[15]Patent:WO2020/69625,2020,A1.Locationinpatent:Page/Pagecolumn111

[1]Sen;Tiwari[JournaloftheIndianChemicalSociety,1952,vol.29,p.419,421,423]

[1]JournalofHeterocyclicChemistry,1986,vol.23,p.567-575

[1]ChemistryofHeterocyclicCompounds,1986,vol.22,p.149-154    KhimiyaGeterotsiklicheskikhSoedinenii,1986,vol.22,p.192-198

[2]Pharmazie,1984,vol.39,p.741-744

[3]JournalofEnzymeInhibitionandMedicinalChemistry,2020,vol.35,p.1513-1523

Literature
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SDS
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