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Title: Synthesis and antiviral activities of hexadecyloxypropyl prodrugs of acyclic nucleoside phosphonates containing guanine or hypoxanthine and a (S)-HPMP or PEE acyclic moiety.
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Title: Characterization of pyrimidine nucleoside phosphorylase of Mycoplasma hyorhinis: implications for the clinical efficacy of nucleoside analogues.
Journal: The Biochemical journal 20120701
Title: Synthesis and antiviral evaluation of C5-substituted-(1,3-diyne)-2'-deoxyuridines.
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Title: 2-Aminopyrimidine based 4-aminoquinoline anti-plasmodial agents. Synthesis, biological activity, structure-activity relationship and mode of action studies.
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Title: Design, synthesis, antiviral and cytostatic evaluation of novel isoxazolidine nucleotide analogues with a 1,2,3-triazole linker.
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Title: Antivirals for management of herpes zoster including ophthalmicus: a systematic review of high-quality randomized controlled trials.
Journal: Antiviral therapy 20120101
Title: Potent anticancer effects of lentivirus encoding a Drosophila melanogaster deoxyribonucleoside kinase mutant combined with brivudine.
Journal: Asian Pacific journal of cancer prevention : APJCP 20120101
Title: RP101 (brivudine) binds to heat shock protein HSP27 (HSPB1) and enhances survival in animals and pancreatic cancer patients.
Journal: Journal of cancer research and clinical oncology 20110901
Title: Phenotypic and genetic characterization of varicella-zoster virus mutants resistant to acyclovir, brivudine and/or foscarnet.
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Title: Expression of herpes simplex virus type 1 recombinant thymidine kinase and its application to a rapid antiviral sensitivity assay.
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Title: Design, synthesis and biological evaluation of 2'-deoxy-2',2'-difluoro-5-halouridine phosphoramidate ProTides.
Journal: Bioorganic & medicinal chemistry 20110715
Title: New prodrugs of Adefovir and Cidofovir.
Journal: Bioorganic & medicinal chemistry 20110601
Title: Synthesis of new C5-(1-substituted-1,2,3-triazol-4 or 5-yl)-2'-deoxyuridines and their antiviral evaluation.
Journal: European journal of medicinal chemistry 20110201
Title: Novel antiviral C5-substituted pyrimidine acyclic nucleoside phosphonates selected as human thymidylate kinase substrates.
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Title: Novel resistance-associated mutations of thymidine kinase and DNA polymerase genes of herpes simplex virus type 1 and type 2.
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Title: 4-[1-(Substituted aryl/alkyl carbonyl)-benzoimidazol-2-yl]-benzenesulfonic acids: synthesis, antimicrobial activity, QSAR studies, and antiviral evaluation.
Journal: European journal of medicinal chemistry 20101201
Title: Synthesis of ester prodrugs of 9-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-2,6-diaminopurine (HPMPDAP) as anti-poxvirus agents.
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Title: [64-year-old patient with efflorescences on the upper and lower legs].
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Title: Epstein-Barr virus encephalitis after kidney transplantation and successful treatment with brivudine.
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Title: Phenotypic and genotypic characterization of acyclovir-resistant clinical isolates of herpes simplex virus.
Journal: Antiviral research 20100601
Title: 'Viologen' dendrimers as antiviral agents: the effect of charge number and distance.
Journal: Journal of medicinal chemistry 20100513
Title: Synthesis, antibacterial and antiviral properties of curcumin bioconjugates bearing dipeptide, fatty acids and folic acid.
Journal: European journal of medicinal chemistry 20100301
Title: Interaction between capecitabine and brivudin in a patient with breast cancer.
Journal: Nature reviews. Clinical oncology 20100101
Title: Disseminated cutaneous herpes zoster complicated by acyclovir nephrotoxicity and successfully treated with brivudin.
Journal: European journal of dermatology : EJD 20100101
Title: Retained sensitivity to cytotoxic pyrimidine nucleoside analogs in thymidine kinase 2 deficient human fibroblasts.
Journal: Nucleosides, nucleotides & nucleic acids 20100101
Title: Acute hepatitis due to brivudin: a case report.
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Title: Synthesis, antiviral and anticancer activity of some novel thioureas derived from N-(4-nitro-2-phenoxyphenyl)-methanesulfonamide.
Journal: European journal of medicinal chemistry 20090901
Title: Synthesis and antiviral activity of new pyrazole and thiazole derivatives.
Journal: European journal of medicinal chemistry 20090901
Title: Synthesis and anti-VZV activity of 6-heteroaryl derivatives of tricyclic acyclovir and 9-{[cis-1',2'-bis(hydroxymethyl)cycloprop-1'-yl]methyl}guanine analogues.
Journal: European journal of medicinal chemistry 20090801
Title: Synthesis, antimicrobial and antiviral evaluation of substituted imidazole derivatives.
Journal: European journal of medicinal chemistry 20090601
Title: Inhibition of homologous recombination by treatment with BVDU (brivudin) or by RAD51 silencing increases chromosomal damage induced by bleomycin in mismatch repair-deficient tumour cells.
Journal: Mutation research 20090512
Title: Indolylarylsulfones bearing natural and unnatural amino acids. Discovery of potent inhibitors of HIV-1 non-nucleoside wild type and resistant mutant strains reverse transcriptase and coxsackie B4 virus.
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Title: 4-Benzyloxy-gamma-sultone derivatives: discovery of a novel family of non-nucleoside inhibitors of human cytomegalovirus and varicella zoster virus.
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Title: Fatal drug-drug interaction of brivudine and capecitabine.
Journal: Acta oncologica (Stockholm, Sweden) 20090101
Title: Influence of 6- or 8-substitution on the antiviral activity of 3-arylalkylthiomethylimidazo[1,2-a]pyridine against human cytomegalovirus (CMV) and varicella-zoster virus (VZV): part II.
Journal: Bioorganic & medicinal chemistry 20081101
Title: Synthesis of nucleoside-based antiviral drugs in ionic liquids.
Journal: Bioorganic & medicinal chemistry letters 20081015
Title: Synthesis and antiviral evaluation of acyclic azanucleosides developed from sulfanilamide as a lead structure.
Journal: Bioorganic & medicinal chemistry 20080915
Title: 5-Bromovinyl 2'-deoxyuridine phosphorylation by mitochondrial and cytosolic thymidine kinase (TK2 and TK1) and its use in selective measurement of TK2 activity in crude extracts.
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Title: [Case report: again just an idiopathic facial nerve palsy?].
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Title: Structural studies of nucleoside analog and feedback inhibitor binding to Drosophila melanogaster multisubstrate deoxyribonucleoside kinase.
Journal: The FEBS journal 20080501
Title: Synthesis and antitumor activity of a heterodinucleotide of BVDU and gemcitabine.
Journal: Nucleosides, nucleotides & nucleic acids 20080501
Title: Synthesis of some novel thiourea derivatives obtained from 5-[(4-aminophenoxy)methyl]-4-alkyl/aryl-2,4-dihydro-3H-1,2,4-triazole-3-thiones and evaluation as antiviral/anti-HIV and anti-tuberculosis agents.
Journal: European journal of medicinal chemistry 20080201
Title: 6-Azathymidine-4'-thionucleosides: synthesis and antiviral evaluation.
Journal: Journal of enzyme inhibition and medicinal chemistry 20080201
Title: Perineal muco-cutaneous herpes zoster treated with brivudin.
Journal: The Journal of dermatological treatment 20080101
Title: Synthesis and antiviral activity of the carbocyclic analogue of the highly potent and selective anti-VZV bicyclo furano pyrimidines.
Journal: Journal of medicinal chemistry 20071227
Title: Influence of 6 or 8-substitution on the antiviral activity of 3-phenethylthiomethylimidazo[1,2-a]pyridine against human cytomegalovirus (HCMV) and varicella-zoster virus (VZV).
Journal: Bioorganic & medicinal chemistry 20071115
Title: Ester prodrugs of cyclic 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-5-azacytosine: synthesis and antiviral activity.
Journal: Journal of medicinal chemistry 20071115
Title: Synthesis and antiviral and cytostatic evaluations of the new C-5 substituted pyrimidine and furo[2,3-d]pyrimidine 4',5'-didehydro-L-ascorbic acid derivatives.
Journal: Journal of medicinal chemistry 20070823
Title: Synthesis and antiviral evaluation of 6-(alkyl-heteroaryl)furo[2,3-d]pyrimidin-2(3H)-one nucleosides and analogues with ethynyl, ethenyl, and ethyl spacers at C6 of the furopyrimidine core.
Journal: Journal of medicinal chemistry 20070809
Title: Novel C-6 fluorinated acyclic side chain pyrimidine derivatives: synthesis, (1)H and (13)C NMR conformational studies, and antiviral and cytostatic evaluations.
Journal: Journal of medicinal chemistry 20070628
Title: 5-alkynyl analogs of arabinouridine and 2'-deoxyuridine: cytostatic activity against herpes simplex virus and varicella-zoster thymidine kinase gene-transfected cells.
Journal: Journal of medicinal chemistry 20070614
Title: 9-(2-C-Cyano-2-deoxy-beta-D-arabino-pentofuranosyl)guanine, a potential antitumor agent against B-lymphoma infected with Kaposi's sarcoma-associated herpesvirus.
Journal: Journal of medicinal chemistry 20070503
Title: Antiviral activity of triazine analogues of 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine (cidofovir) and related compounds.
Journal: Journal of medicinal chemistry 20070308
Title: The novel C-5 aryl, alkenyl, and alkynyl substituted uracil derivatives of L-ascorbic acid: synthesis, cytostatic, and antiviral activity evaluations.
Journal: Bioorganic & medicinal chemistry 20070115
Title: Recommendations for the management of herpes zoster.
Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20070101
Title: Molecular modelling studies on the binding of some protides to the putative human phosphoramidase Hint1.
Journal: Nucleosides, nucleotides & nucleic acids 20070101
Title: Synthesis, in vitro antiviral evaluation, and stability studies of novel alpha-borano-nucleotide analogues of 9-[2-(phosphonomethoxy)ethyl]adenine and (R)-9-[2-(phosphonomethoxy)propyl]adenine.
Journal: Journal of medicinal chemistry 20061228
Title: RP101 improves the efficacy of chemotherapy in pancreas carcinoma cell lines and pancreatic cancer patients.
Journal: Anti-cancer drugs 20061001
Title: Bromovinyl-deoxyuridine: A selective substrate for mitochondrial thymidine kinase in cell extracts.
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Title: New antiviral agents.
Journal: Indian journal of pediatrics 20060401
Title: Inactivation of S-adenosyl-L-homocysteine hydrolase by 6'-cyano-5',6'-didehydro-6'-deoxyhomoadenosine and 6'-chloro-6'-cyano-5',6'-didehydro-6'-deoxyhomoadenosine. Antiviral and cytotoxic effects.
Journal: Journal of medicinal chemistry 20060223
Title: Linear Darier disease with herpes zoster superinfection treated successfully by brivudine.
Journal: The British journal of dermatology 20060201
Title: Synthesis and biological activity of isoxazolidinyl polycyclic aromatic hydrocarbons: potential DNA intercalators.
Journal: Journal of medicinal chemistry 20060126
Title: Synthesis and biological evaluation of 6-(alkyn-1-yl)furo[2,3-d]pyrimidin-2(3H)-one base and nucleoside derivatives.
Journal: Journal of medicinal chemistry 20060112
Title: Inhibitory efficacy of cyclosal-nucleoside monophosphates of aciclovir and brivudin on DNA synthesis of orthopoxvi ruses.
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Title: [Varicella-zoster virus infections--2: Zoster pain -- therapy and prevention].
Journal: MMW Fortschritte der Medizin 20060101
Title: Synthesis and in vitro anti-mycobacterial activity of 5-substituted pyrimidine nucleosides.
Journal: Bioorganic & medicinal chemistry 20051215
Title: Insecticidal activity of the pyrimidine nucleoside analogue (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU).
Journal: Pest management science 20050801
Title: Synthesis and biological evaluation of acyclic 3-[(2-hydroxyethoxy)methyl] analogues of antiviral furo- and pyrrolo[2,3-d]pyrimidine nucleosides.
Journal: Journal of medicinal chemistry 20050714
Title: From 1-acyl-beta-lactam human cytomegalovirus protease inhibitors to 1-benzyloxycarbonylazetidines with improved antiviral activity. A straightforward approach to convert covalent to noncovalent inhibitors.
Journal: Journal of medicinal chemistry 20050407
Title: Antiadenovirus activities of several classes of nucleoside and nucleotide analogues.
Journal: Antimicrobial agents and chemotherapy 20050301
Title: Susceptibilities of several clinical varicella-zoster virus (VZV) isolates and drug-resistant VZV strains to bicyclic furano pyrimidine nucleosides.
Journal: Antimicrobial agents and chemotherapy 20050301
Title: (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU).
Journal: Medicinal research reviews 20050101
Title: Brivudin compared with famciclovir in the treatment of herpes zoster: effects in acute disease and chronic pain in immunocompetent patients. A randomized, double-blind, multinational study.
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Title: [Antiherpetic therapy].
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Title: Naphthyl phosphoramidate derivatives of BVdU as potential anticancer agents: design, synthesis and biological evaluation.
Journal: Nucleosides, nucleotides & nucleic acids 20050101
Title: Current management of herpes zoster: the European view.
Journal: American journal of clinical dermatology 20050101
Title: Discovery and development of BVDU (brivudin) as a therapeutic for the treatment of herpes zoster.
Journal: Biochemical pharmacology 20041215
Title: 6-azapyrimidine-2'-deoxy-4'-thionucleosides: antiviral agents against TK+ and TK- HSV and VZV strains.
Journal: Journal of medicinal chemistry 20041021
Title: Synthesis and antiviral activities of 1'-carbon-substituted 4'-thiothymidines.
Journal: Bioorganic & medicinal chemistry 20041015
Title: Human herpesvirus 6 DNA polymerase: enzymatic parameters, sensitivity to ganciclovir and determination of the role of the A961V mutation in HHV-6 ganciclovir resistance.
Journal: Antiviral research 20041001
Title: Functional expression of thymidine kinase in human leukaemic and colorectal cells, delivered as EGFP fusion protein by herpesvirus saimiri-based vector.
Journal: Cancer gene therapy 20040901
Title: Evaluation of antiviral activity against human herpesvirus 8 (HHV-8) and Epstein-Barr virus (EBV) by a quantitative real-time PCR assay.
Journal: Antiviral research 20040601
Title: Spirobipyridopyrans, spirobinaphthopyrans, indolinospiropyridopyrans, indolinospironaphthopyrans and indolinospironaphtho-1,4-oxazines: synthesis, study of X-ray crystal structure, antitumoral and antiviral evaluation.
Journal: Bioorganic & medicinal chemistry 20040301
Title: In vitro selection of drug-resistant varicella-zoster virus (VZV) mutants (OKA strain): differences between acyclovir and penciclovir?
Journal: Antiviral research 20040301
Title: Brivudin (bromovinyl deoxyuridine).
Journal: Drugs 20040101
Title: Synthesis and biological evaluation of 5-substituted derivatives of the potent antiherpes agent (north)-methanocarbathymine.
Journal: Journal of medicinal chemistry 20031106
Title: Lipid-mediated protein delivery of suicide nucleoside kinases.
Journal: Cancer research 20031015
Title: [Brivudine as an alternative systemic therapy to aciclovir and ganciclovir in acute retinal necrosis syndrome due to varicella-zoster virus].
Journal: Klinische Monatsblatter fur Augenheilkunde 20031001
Title: Synthesis, protonation behavior, conformational analysis, and regioselective enzymatic acylation of the novel diamino analogue of (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU).
Journal: Nucleosides, nucleotides & nucleic acids 20031001
Title: Inhibition of induced chemoresistance by cotreatment with (E)-5-(2-bromovinyl)-2'-deoxyuridine (RP101).
Journal: Cancer research 20030915
Title: Comparative study of purine and pyrimidine nucleoside analogues acting on the thymidylate kinases of Mycobacterium tuberculosis and of humans.
Journal: Chembiochem : a European journal of chemical biology 20030804
Title: Herpes zoster guidelines of the German Dermatological Society.
Journal: Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 20030801
Title: Oral brivudin in comparison with acyclovir for improved therapy of herpes zoster in immunocompetent patients: results of a randomized, double-blind, multicentered study.
Journal: Antiviral research 20030601
Title: Oral brivudin in comparison with acyclovir for herpes zoster: a survey study on postherpetic neuralgia.
Journal: Antiviral research 20030601
Title: Brivudine: a herpes virostatic with rapid antiviral activity and once-daily dosing.
Journal: Drugs of today (Barcelona, Spain : 1998) 20030501
Title: Herpes zoster guideline of the German Dermatology Society (DDG).
Journal: Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 20030401
Title: Homology modelling and docking studies on Varicella Zoster Virus Thymidine kinase.
Journal: European journal of medicinal chemistry 20030401
Title: Enzymatic and structural analysis of inhibitors designed against Mycobacterium tuberculosis thymidylate kinase. New insights into the phosphoryl transfer mechanism.
Journal: The Journal of biological chemistry 20030214
Title: Amino acid changes within conserved region III of the herpes simplex virus and human cytomegalovirus DNA polymerases confer resistance to 4-oxo-dihydroquinolines, a novel class of herpesvirus antiviral agents.
Journal: Journal of virology 20030201
Title: Apoptosis induced by (E)-5-(2-bromovinyl)-2'-deoxyuridine in varicella zoster virus thymidine kinase-expressing cells is driven by activation of c-Jun/activator protein-1 and Fas ligand/caspase-8.
Journal: Molecular pharmacology 20030201
Title: In vitro activity of potential anti-poxvirus agents.
Journal: Antiviral research 20030101
Title: The role of antivirals in the management of neuropathic pain in the older patient with herpes zoster.
Journal: Drugs & aging 20030101
Title: Design of Mycobacterium tuberculosis thymidine monophosphate kinase inhibitors.
Journal: Nucleosides, nucleotides & nucleic acids 20030101
Title: A thymidine phosphorylase-stable analogue of BVDU with significant antiviral activity.
Journal: Journal of medicinal chemistry 20021205
Title: CycloSal-BVDUMP pronucleotides: how to convert an antiviral-inactive nucleoside analogue into a bioactive compound against EBV.
Journal: Journal of medicinal chemistry 20021107
Title: Synthesis and antiviral/antiproliferative activity of some N-sulphonylbenzimidazoles.
Journal: Bioorganic & medicinal chemistry letters 20021007
Title: Chemotherapy of varicella-zoster virus by a novel class of highly specific anti-VZV bicyclic pyrimidine nucleosides.
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Title: Potent in vivo antiviral activity of the herpes simplex virus primase-helicase inhibitor BAY 57-1293.
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Title: Lack of susceptibility of bicyclic nucleoside analogs, highly potent inhibitors of varicella-zoster virus, to the catabolic action of thymidine phosphorylase and dihydropyrimidine dehydrogenase.
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Title: New 2-(1-adamantylcarbonyl)pyridine and 1-acetyladamantane thiosemicarbazones-thiocarbonohydrazones: cell growth inhibitory, antiviral and antimicrobial activity evaluation.
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Title: Alkyloxyphenyl furano pyrimidines as potent and selective anti-VZV agents with enhanced water solubility.
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Title: Specific recognition of the bicyclic pyrimidine nucleoside analogs, a new class of highly potent and selective inhibitors of varicella-zoster virus (VZV), by the VZV-encoded thymidine kinase.
Journal: Molecular pharmacology 20020201
Title: Nucleoside analog cytotoxicity and bystander cell killing of cancer cells expressing Drosophila melanogaster deoxyribonucleoside kinase in the nucleus or cytosol.
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Title: Fluorescent tricyclic analogues of acyclovir and ganciclovir. A structure-antiviral activity study.
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Title: Synthesis and antiviral activity of novel 5-(1-cyanamido-2-haloethyl) and 5-(1-hydroxy(or methoxy)-2-azidoethyl) analogues of uracil nucleosides.
Journal: Journal of medicinal chemistry 20011011
Title: Hamao Umezawa Memorial Award Lecture: 'An Odyssey in the Viral Chemotherapy Field'.
Journal: International journal of antimicrobial agents 20011001
Title: Novel carbocyclic nucleosides containing a cyclobutyl ring: adenosine analogues.
Journal: Chemical & pharmaceutical bulletin 20010901
Title: Synthesis and antiviral evaluation of phosphoramidate derivatives of (E)-5-(2-bromovinyl)-2'-deoxyuridine.
Journal: Antiviral chemistry & chemotherapy 20010901
Title: Design, synthesis, DNA binding, and biological evaluation of water-soluble hybrid molecules containing two pyrazole analogues of the alkylating cyclopropylpyrroloindole (CPI) subunit of the antitumor agent CC-1065 and polypyrrole minor groove binders.
Journal: Journal of medicinal chemistry 20010802
Title: Bystander effects of cancer cell lines transduced with the multisubstrate deoxyribonucleoside kinase of Drosophila melanogaster and synergistic enhancement by hydroxyurea.
Journal: Molecular pharmacology 20010801
Title: [Controlling herpes zoster. End end to bullae].
Journal: MMW Fortschritte der Medizin 20010531
Title: Design, synthesis and enzymatic activity of highly selective human mitochondrial thymidine kinase inhibitors.
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Title: (E)-5-(2-bromovinyl)-2'-deoxyuridine potentiates ganciclovir-mediated cytotoxicity on herpes simplex virus-thymidine kinase--expressing cells.
Journal: Cancer gene therapy 20010501
Title: cycloSaligenyl-5-[(E)-2-bromovinyl]-2'-deoxyuridine monophosphate (cycloSal-BVDUMP) pronucleotides active against Epstein-Barr virus.
Journal: Chembiochem : a European journal of chemical biology 20010402
Title: Vaccinia virus inhibitors as a paradigm for the chemotherapy of poxvirus infections.
Journal: Clinical microbiology reviews 20010401
Title: Recent developments in herpesvirus therapy.
Journal: Herpes : the journal of the IHMF 20010301
Title: Enzyme-catalyzed therapeutic agent (ECTA) design: activation of the antitumor ECTA compound NB1011 by thymidylate synthase.
Journal: Biochemical pharmacology 20010115
Title: Synthesis of 1-(2-deoxy-beta-D-ribofuranosyl)-2,4-difluoro-5-substituted-benzene thymidine mimics, some related alpha-anomers, and their evaluation as antiviral and anticancer agents.
Journal: Nucleosides, nucleotides & nucleic acids 20010101
Title: Antiviral agents active against human herpesviruses HHV-6, HHV-7 and HHV-8.
Journal: Reviews in medical virology 20010101
Title: Human glioma cells expressing herpes simplex virus thymidine kinase gene treated with acyclovir, ganciclovir and bromovinyldeoxyuridine. Evaluation of their activity in vitro and in nude mice.
Journal: Neoplasma 20010101
Title: Highly potent and selective inhibition of varicella-zoster virus by bicyclic furopyrimidine nucleosides bearing an aryl side chain.
Journal: Journal of medicinal chemistry 20001228
Title: Metabolism and mode of inhibition of varicella-zoster virus by L-beta-5-bromovinyl-(2-hydroxymethyl)-(1,3-dioxolanyl)uracil is dependent on viral thymidine kinase.
Journal: Molecular pharmacology 20001101
Title: Anti-(herpes simplex virus) activity of 4'-thio-2'-deoxyuridines: a biochemical investigation for viral and cellular target enzymes.
Journal: The Biochemical journal 20001015
Title: Structure-activity relationships of (E)-5-(2-bromovinyl)uracil and related pyrimidine nucleosides as antiviral agents for herpes viruses.
Journal: Journal of medicinal chemistry 20000629
Title: A rapid phenotypic assay for detection of acyclovir-resistant varicella-zoster virus with mutations in the thymidine kinase open reading frame.
Journal: Antimicrobial agents and chemotherapy 20000401
Title: Antiviral activity of ganciclovir elaidic acid ester against herpesviruses.
Journal: Antiviral research 20000301
Title: The cyclohexene ring system as a furanose mimic: synthesis and antiviral activity of both enantiomers of cyclohexenylguanine.
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Title: Hydroxyurea potentiates the antiherpesvirus activities of purine and pyrimidine nucleoside and nucleoside phosphonate analogs.
Journal: Antimicrobial agents and chemotherapy 19991201
Title: Potent and selective inhibition of varicella-zoster virus (VZV) by nucleoside analogues with an unusual bicyclic base.
Journal: Journal of medicinal chemistry 19991104
Title: Phenotypic and genetic characterization of thymidine kinase from clinical strains of varicella-zoster virus resistant to acyclovir.
Journal: Antimicrobial agents and chemotherapy 19991001
Title: Selective activity of various antiviral compounds against HHV-7 infection.
Journal: Antiviral research 19990801
Title: Synthesis of novel 4'-C-methyl-pyrimidine nucleosides and their biological activities.
Journal: Bioorganic & medicinal chemistry letters 19990322
Title: Synthesis of imidazo[1,2-a]pyridines as antiviral agents.
Journal: Journal of medicinal chemistry 19981203
Title: Efficacy of select antivirals against Cryptosporidium parvum in vitro.
Journal: FEMS microbiology letters 19981101
Title: 5-Substituted pyrimidines with a 1,5-anhydro-2, 3-dideoxy-D-arabino-hexitol moiety at N-1: synthesis, antiviral activity, conformational analysis, and interaction with viral thymidine kinase.
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Title: Structure-activity relationship of the affinity of 5-substituted uracil nucleoside analogues for varicella-zoster virus thymidine kinase and their activity against varicella-zoster virus.
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Title: Anticancer and antiviral effects and inactivation of S-adenosyl-L-homocysteine hydrolase with 5'-carboxaldehydes and oximes synthesized from adenosine and sugar-modified analogues.
Journal: Journal of medicinal chemistry 19970523
Title: Carbocyclic oxetanocins lacking the C-3' methylene.
Journal: Journal of medicinal chemistry 19970425
Title: Novel 3'-C/N-substituted 2',3'-beta-D-dideoxynucleosides as potential chemotherapeutic agents. 1. Thymidine derivatives: synthesis, structure, and broad spectrum antiviral properties.
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Title: Antiviral efficacies of famciclovir, valaciclovir, and brivudin in disseminated herpes simplex virus type 1 infection in mice.
Journal: Intervirology 19970101
Title: Understanding the binding of 5-substituted 2'-deoxyuridine substrates to thymidine kinase of herpes simplex virus type-1.
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Title: Synthesis of acyclo-C-nucleosides in the imidazo[1,2-a]pyridine and pyrimidine series as antiviral agents.
Journal: Journal of medicinal chemistry 19960705
Title: Synthesis and anti-herpes virus activity of 2'-deoxy-4'-thiopyrimidine nucleosides.
Journal: Journal of medicinal chemistry 19960202
Title: Antiviral activity of selected acyclic nucleoside analogues against human herpesvirus 6.
Journal: Antiviral research 19951201
Title: Susceptibilities of several drug-resistant herpes simplex virus type 1 strains to alternative antiviral compounds.
Journal: Antimicrobial agents and chemotherapy 19950701
Title: Comparative activity of selected antiviral compounds against clinical isolates of varicella-zoster virus.
Journal: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 19950401
Title: Lack of stereospecificity of some cellular and viral enzymes involved in the synthesis of deoxyribonucleotides and DNA: molecular basis for the antiviral activity of unnatural L-beta-nucleosides.
Journal: Biochimie 19950101
Title: Tricyclic analogues of acyclovir and ganciclovir. Influence of substituents in the heterocyclic moiety on the antiviral activity.
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Title: Stereoelectronic properties of five anti-HSV-1 2'-deoxynucleosides analogues with heterocyclic substituents in the 5-position: a comparison with BVDU.
Journal: Antiviral research 19940801
Title: Synthesis and antiviral activities of 8-alkynyl-, 8-alkenyl-, and 8-alkyl-2'-deoxyadenosine analogues.
Journal: Journal of medicinal chemistry 19940429
Title: S-glucosylated hydantoins as new antiviral agents.
Journal: Journal of medicinal chemistry 19940107
Title: Antiviral activity of C-alkylated purine nucleosides obtained by cross-coupling with tetraalkyltin reagents.
Journal: Journal of medicinal chemistry 19931001
Title: Synthesis and antiherpes virus activity of 1,5-anhydrohexitol nucleosides.
Journal: Journal of medicinal chemistry 19930709
Title: Synthesis and antiviral properties of (+/-)-5'-noraristeromycin and related purine carbocyclic nucleosides. A new lead for anti-human cytomegalovirus agent design.
Journal: Journal of medicinal chemistry 19920904
Title: Antiviral and antitumor structure-activity relationship studies on tetracyclic eudistomines.
Journal: Journal of medicinal chemistry 19920821
Title: (+-)-carbocyclic 5'-nor-2'-deoxyguanosine and related purine derivatives: synthesis and antiviral properties.
Journal: Journal of medicinal chemistry 19920612
Title: The synthesis and antiviral activity of some 4'-thio-2'-deoxy nucleoside analogues.
Journal: Journal of medicinal chemistry 19910901
Title: 5-(5-Bromothien-2-yl)-2'-deoxyuridine and 5-(5-chlorothien-2-yl)-2'-deoxyuridine are equipotent to (E)-5-(2-bromovinyl)-2'-deoxyuridine in the inhibition of herpes simplex virus type I replication.
Journal: Journal of medicinal chemistry 19910801
Title: Synthesis and antiviral activity of 5-heteroaryl-substituted 2'-deoxyuridines.
Journal: Journal of medicinal chemistry 19910601
Title: Synthesis and antiviral activity of 3'-deoxy-3'-C-hydroxymethyl nucleosides.
Journal: Journal of medicinal chemistry 19900901
Title: Comparative activities of several nucleoside analogs against duck hepatitis B virus in vitro.
Journal: Antimicrobial agents and chemotherapy 19900701
Title: Stereospecific synthesis and antiviral properties of different enantiomerically pure carbocyclic 2'-deoxyribonucleoside analogues derived from common chiral pools: (+)-(1R,5S)- and (-)-(1S,5R)-2-oxabicyclo[3.3.0]oct-6-en-3-one.
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Title: Comparison of two bromovinyl nucleoside analogs, 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil and E-5-(2-bromovinyl)-2'-deoxyuridine, with acyclovir in inhibition of Epstein-Barr virus replication.
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Title: Synthesis and antiviral activity of the carbocyclic analogues of (E)-5-(2-halovinyl)-2'-deoxyuridines and (E)-5-(2-halovinyl)-2'-deoxycytidines.
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Title: Uridine 5'-diphosphate glucose analogues. Inhibitors of protein glycosylation that show antiviral activity.
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Journal: Antiviral research 19840801
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