Home Amines 7149-10-2
7149-10-2,MFCD00012864
Catalog No.:AA003LF5

7149-10-2 | 4-Hydroxy-3-methoxybenzylamine, HCl

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5g
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$6.00   $4.00
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10g
98%
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$7.00   $5.00
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25g
98%
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$16.00   $11.00
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100g
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$62.00   $43.00
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500g
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  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003LF5
Chemical Name:
4-Hydroxy-3-methoxybenzylamine, HCl
CAS Number:
7149-10-2
Molecular Formula:
C8H11ClNO2
Molecular Weight:
188.6314
MDL Number:
MFCD00012864
SMILES:
COc1cc(CN)ccc1O.[Cl]
NSC Number:
62020
Properties
Properties
 
BP:
292.9°C at 760 mmHg  
Form:
Solid  
MP:
219-221 °C (dec.);(lit.);  
Stability:
Moisture Sensitive  
Storage:
Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
119  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
12  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
2  

Upstream Synthesis Route

[1]Patent:,2016,,.Locationinpatent:Paragraph0040;0041;0042

[2]JournalofAgriculturalandFoodChemistry,2010,vol.58,#6,p.3342-3349

[1]Patent:CN103288665,2017,B,.Locationinpatent:Paragraph0029;0031;0032;0034

[1]Polymer,2011,vol.52,#9,p.1908-1916

[2]JournalofOrganicChemistry,1988,vol.53,#5,p.1064-1071

[3]Patent:CN106366004,2017,A,.Locationinpatent:Paragraph0017-0028

[4]Patent:JP2005/527478,2005,A,.Locationinpatent:Page/Pagecolumn4

[5]RussianChemicalBulletin,2018,vol.67,#8,p.1394-1400

[6]Izv.Akad.Nauk,Ser.Khim.,2018,#8,p.1394-1400,7

[7]Patent:JP2005/527478,2005,A,.Locationinpatent:Page/Pagecolumn4

[8]Patent:EP2511283,2012,A1,.Locationinpatent:Page/Pagecolumn49

[9]Patent:US2013/45942,2013,A1,.Locationinpatent:Paragraph0162

[10]Patent:JP2015/172077,2015,A,.Locationinpatent:Paragraph0115

[1]Patent:EP2511283,2012,A1,

[2]Patent:US2013/45942,2013,A1,

[3]Patent:CN103288665,2017,B,.Locationinpatent:Paragraph0029;0030;0032;0033

[4]JournalofMedicinalChemistry,2018,vol.61,#18,p.8255-8281

[1]JournalofMedicinalChemistry,2018,vol.61,#18,p.8255-8281

Downstream Synthesis Route

[1]Locationinpatent:experimentalpartLiu,Hefang;Lepoittevin,Bénédicte;Roddier,Céline;Guerineau,Vincent;Bech,Loïc;Herry,Jean-Marie;Bellon-Fontaine,Marie-Noelle;Roger,Philippe[Polymer,2011,vol.52,#9,p.1908-1916]

[2]Gannett,PeterM.;Nagel,DonaldL.;Reilly,PamJ.;Lawson,Terence;Sharpe,Jody;Toth,Bela[JournalofOrganicChemistry,1988,vol.53,#5,p.1064-1071]

[3]CurrentPatentAssignee:HENANCHEMICALINDRESINST-CN106366004,2017,ALocationinpatent:Paragraph0017-0028

[4]CurrentPatentAssignee:C.H.BoehringerSohnAG&Co.KG-JP2005/527478,2005,ALocationinpatent:Page/Pagecolumn4

[5]Ignatov;Varakutin;Solov’eva;Karmanova;Kozlov;Semenova;Semenov[RussianChemicalBulletin,2018,vol.67,#8,p.1394-1400][Izv.Akad.Nauk,Ser.Khim.,2018,#8,p.1394-1400,7]

[6]CurrentPatentAssignee:C.H.BoehringerSohnAG&Co.KG-JP2005/527478,2005,ALocationinpatent:Page/Pagecolumn4

[7]CurrentPatentAssignee:CHINESEACADEMYOFMEDICALSCIENCES-EP2511283,2012,A1Locationinpatent:Page/Pagecolumn49

[8]CurrentPatentAssignee:CHINESEACADEMYOFMEDICALSCIENCES-US2013/45942,2013,A1Locationinpatent:Paragraph0162

[9]CurrentPatentAssignee:CHINESEACADEMYOFMEDICALSCIENCES-JP2015/172077,2015,ALocationinpatent:Paragraph0115

[1]CurrentPatentAssignee:KUREHACORP.-US2004/110844,2004,A1Locationinpatent:Page/Pagecolumn4

[2]Kobata,Kenji;Yoshikawa,Koichi;Kohashi,Masahiro;Watanabe,Tatsuo[TetrahedronLetters,1996,vol.37,#16,p.2789-2790]

[1]Pei,Fang-Ning;Tang,Jie;Wang,Zhi-Cheng;Wei,Bingyan;Yang,Cai-Guang;Yang,Fan;Yang,Song;Yang,Teng;Yu,Li-Fang[EuropeanJournalofMedicinalChemistry,2020,vol.198]

[2]Lee,Jeewoo;Lee,Jiyoun;Kang,Myung-Sim;Kim,Kang-Pil;Chung,Suk-Jae;Blumberg,PeterM.;Yi,Jung-Bum;Park,YoungHo[BioorganicandMedicinalChemistry,2002,vol.10,#4,p.1171-1179]

[3]CurrentPatentAssignee:JOHNSON&JOHNSONINC-WO2007/81995,2007,A2Locationinpatent:Page/Pagecolumn196

[4]Wrigglesworth,Roger;Walpole,ChristopherS.J.;Bevan,Stuart;Campbell,ElizabethA.;Dray,Andy;Hughes,GlynA.;James,Iain;Masdin,KayJ.;Winter,Janet[JournalofMedicinalChemistry,1996,vol.39,#25,p.4942-4951]

[5]Bata,Imre;Tömösközi,Zsuzsanna;Buzder-Lantos,Péter;Vasas,Attila;Szeleczky,Gábor;Bátori,Sándor;Barta-Bodor,Veronika;Balázs,László;Ferenczy,GyörgyG.[BioorganicandMedicinalChemistryLetters,2016,vol.26,#22,p.5418-5428]

[1]Wrigglesworth,Roger;Walpole,ChristopherS.J.;Bevan,Stuart;Campbell,ElizabethA.;Dray,Andy;Hughes,GlynA.;James,Iain;Masdin,KayJ.;Winter,Janet[JournalofMedicinalChemistry,1996,vol.39,#25,p.4942-4951]

trans-ximenynicacid 
  7149-10-2   
(E)-Octadec-11-en-9-ynoicacid4-hydroxy-3-methoxy-benzylamide 

[1]Appendino,Giovanni;Minassi,Alberto;Morello,AnielloSchiano;DePetrocellis,Luciano;DiMarzo,Vincenzo[JournalofMedicinalChemistry,2002,vol.45,#17,p.3739-3745]

Literature

Title: Functional validation of Capsicum frutescens aminotransferase gene involved in vanillylamine biosynthesis using Agrobacterium mediated genetic transformation studies in Nicotiana tabacum and Capsicum frutescens calli cultures.

Journal: Plant science : an international journal of experimental plant biology 20121001

Title: Synthesis of stable isotope-labeled precursors for the biosyntheses of capsaicinoids, capsinoids, and capsiconinoids.

Journal: Bioscience, biotechnology, and biochemistry 20110101

Title: Functional loss of pAMT results in biosynthesis of capsinoids, capsaicinoid analogs, in Capsicum annuum cv. CH-19 Sweet.

Journal: The Plant journal : for cell and molecular biology 20090901

Title: Valine pathway is more crucial than phenyl propanoid pathway in regulating capsaicin biosynthesis in Capsicum frutescens mill.

Journal: Journal of agricultural and food chemistry 20060906

Title: Utilization of capsaicin and vanillylamine as growth substrates by Capsicum (hot pepper)-associated bacteria.

Journal: Environmental microbiology 20060301

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Tags:7149-10-2 Molecular Formula|7149-10-2 MDL|7149-10-2 SMILES|7149-10-2 4-Hydroxy-3-methoxybenzylamine, HCl |Organic_Building_Blocks