Name: Name:Benzamide, N-(2-aminophenyl)-
Brand: AABLOCKS
SKU: AA00FTHS
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA00FTHS

Chemical Name: Benzamide, N-(2-aminophenyl)-

CAS Number: 721-47-1

Molecular Formula: C13H12N2O

Molecular Weight: 212.2472

MDL Number: MFCD00034792

SMILES: C1=CC=C(C=C1)C(=O)NC2=CC=CC=C2N

Properties

Complexity: 236

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 16

Hydrogen Bond Acceptor Count: 2

Hydrogen Bond Donor Count: 2

Isotope Atom Count: 0

Rotatable Bond Count: 2

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: 1.9

Literature fold

Title: Exploring inhibitor release pathways in histone deacetylases using random acceleration molecular dynamics simulations.

Journal: Journal of chemical information and modeling20120227

Title: 3D QSAR of aminophenyl benzamide derivatives as histone deacetylase inhibitors.

Journal: Medicinal chemistry (Shariqah (United Arab Emirates))20100901

Title: Exploration of the HDAC2 foot pocket: Synthesis and SAR of substituted N-(2-aminophenyl)benzamides.

Journal: Bioorganic & medicinal chemistry letters20100515

Title: Epigenetic treatment of myelodysplastic syndromes and acute myeloid leukemias.

Journal: Current medicinal chemistry20080601

Title: Exploration of the internal cavity of histone deacetylase (HDAC) with selective HDAC1/HDAC2 inhibitors (SHI-1:2).

Journal: Bioorganic & medicinal chemistry letters20080201

Title: Effects of a novel histone deacetylase inhibitor, N-(2-aminophenyl) benzamide, on a reversible hypertrophy induced by isoproterenol in in situ rat hearts.

Journal: Journal of pharmacological sciences20070601

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology20060501

721-47-1 | Benzamide, N-(2-aminophenyl)-