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724709-68-6,MFCD06798350
Catalog No.:AA00FDLZ

724709-68-6 | PHENOLPHTHALEIN DIPHOSPHATE TETRASODIUM

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1mg
≥98%
in stock  
$46.00   $32.00
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5mg
≥98%
in stock  
$199.00   $139.00
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10mg
≥98%
in stock  
$329.00   $230.00
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25mg
≥98%
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$762.00   $533.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00FDLZ
Chemical Name:
PHENOLPHTHALEIN DIPHOSPHATE TETRASODIUM
CAS Number:
724709-68-6
Molecular Formula:
C21H18O4
Molecular Weight:
334.3652
MDL Number:
MFCD06798350
SMILES:
O=c1ccc2c(o1)cc1c(c2OCCCCc2ccccc2)cco1
Properties
Computed Properties
 
Complexity:
482  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
25  
Hydrogen Bond Acceptor Count:
4  
Rotatable Bond Count:
6  
XLogP3:
5  

Literature

Title: Psora-4, a Kv1.3 Blocker, Enhances Differentiation and Maturation in Neural Progenitor Cells.

Journal: CNS neuroscience & therapeutics 20150701

Title: Inhibitors of mitochondrial Kv1.3 channels induce Bax/Bak-independent death of cancer cells.

Journal: EMBO molecular medicine 20120701

Title: Kv1.3 channels as a potential target for immunomodulation of CD4+ CD28null T cells in patients with acute coronary syndrome.

Journal: Clinical immunology (Orlando, Fla.) 20120201

Title: Pharmacological inhibition of Kv1.3 fails to modulate insulin sensitivity in diabetic mice or human insulin-sensitive tissues.

Journal: American journal of physiology. Endocrinology and metabolism 20110801

Title: Identification of phase-I metabolites and chronic toxicity study of the Kv1.3 blocker PAP-1 (5-(4-phenoxybutoxy)psoralen) in the rat.

Journal: Xenobiotica; the fate of foreign compounds in biological systems 20110301

Title: Potent suppression of vascular smooth muscle cell migration and human neointimal hyperplasia by KV1.3 channel blockers.

Journal: Cardiovascular research 20110201

Title: Voltage-gated potassium channel Kv1.3 blocker as a potential treatment for rat anti-glomerular basement membrane glomerulonephritis.

Journal: American journal of physiology. Renal physiology 20101201

Title: N-{3-[(1,1-dioxido-1,2-benzothiazol-3-yl)(phenyl)amino]propyl}benzamide analogs as potent Kv1.3 inhibitors. Part 1.

Journal: Bioorganic & medicinal chemistry letters 20101201

Title: Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Journal: Nature chemical biology 20091001

Title: Transient 5-(4-phenylbutoxy)psoralen (PAP-1) treatment dissociates developing pathologies in autoimmune optic neuritis into two distinct pathology profiles.

Journal: Journal of neuroscience research 20080701

Title: Pharmacokinetics, toxicity, and functional studies of the selective Kv1.3 channel blocker 5-(4-phenoxybutoxy)psoralen in rhesus macaques.

Journal: Experimental biology and medicine (Maywood, N.J.) 20071101

Title: 5-(3-Phenylpropoxy)psoralen and 5-(4-phenylbutoxy)psoralen: mechanistic studies on phototoxicity.

Journal: Die Pharmazie 20050301

Title: Kv1.3-blocking 5-phenylalkoxypsoralens: a new class of immunomodulators.

Journal: Molecular pharmacology 20040601

Title: The voltage-gated Kv1.3 K(+) channel in effector memory T cells as new target for MS.

Journal: The Journal of clinical investigation 20030601

Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

Journal: The Journal of biological chemistry 20020419

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