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72509-76-3,MFCD00868316
Catalog No.:AA005SIC

72509-76-3 | 3-ethyl 5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate

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10mg
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50mg
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1g
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5g
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10g
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25g
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA005SIC
Chemical Name:
3-ethyl 5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
CAS Number:
72509-76-3
Molecular Formula:
C18H19Cl2NO4
Molecular Weight:
384.2538
MDL Number:
MFCD00868316
SMILES:
CCOC(=O)C1=C(C)NC(=C(C1c1cccc(c1Cl)Cl)C(=O)OC)C
NSC Number:
760343
Properties
Properties
 
BP:
471.5°C at 760 mmHg  
Form:
Solid  
MP:
142-145°C  
Refractive Index:
1.6500 (estimate)  
Solubility:
DMSO: 28 mg/mL  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
614  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
25  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
6  
Undefined Atom Stereocenter Count:
1  
XLogP3:
3.9  

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Title: Preparation of a solid dispersion of felodipine using a solvent wetting method.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20061001

Title: A comparison of the physical stability of amorphous felodipine and nifedipine systems.

Journal: Pharmaceutical research 20061001

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Title: Application of PVP/HPMC miscible blends with enhanced mucoadhesive properties for adjusting drug release in predictable pulsatile chronotherapeutics.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20060801

Title: Effect of hydrogen bonding interactions on the release mechanism of felodipine from nanodispersions with polyvinylpyrrolidone.

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Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Micronization and microencapsulation of felodipine by supercritical carbon dioxide.

Journal: Journal of microencapsulation 20060501

Title: Effect of grapefruit juice in relation to human pharmacokinetic study.

Journal: Current clinical pharmacology 20060501

Title: Felodipine nanodispersions as active core for predictable pulsatile chronotherapeutics using PVP/HPMC blends as coating layer.

Journal: International journal of pharmaceutics 20060426

Title: Impaired capacity for stimulated fibrinolysis in primary hypertension is restored by antihypertensive therapy.

Journal: Hypertension (Dallas, Tex. : 1979) 20060401

Title: A factorial study of combination hypertension treatment with metoprolol succinate extended release and felodipine extended release results of the Metoprolol Succinate-Felodipine Antihypertension Combination Trial (M-FACT).

Journal: American journal of hypertension 20060401

Title: CACNA1C polymorphisms are associated with the efficacy of calcium channel blockers in the treatment of hypertension.

Journal: Pharmacogenomics 20060401

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Title: AT1 receptor antagonism improves endothelial dysfunction in postmenopausal women.

Journal: Maturitas 20060120

Title: Sympatho-excitatory responses to once-daily dihydropyridines in young versus older hypertensive patients: amlodipine versus felodipine extended release.

Journal: Journal of hypertension 20060101

Title: Hypertensive urgency.

Journal: Journal of clinical hypertension (Greenwich, Conn.) 20060101

Title: Comparative study of barnidipine and felodipine in Chinese patients with essential hypertension.

Journal: The Journal of international medical research 20060101

Title: A review of calcium channel antagonists in the treatment of pediatric hypertension.

Journal: Paediatric drugs 20060101

Title: Thermal stability of 1,4-dihydropyridine derivatives in solid state.

Journal: Acta poloniae pharmaceutica 20060101

Title: More heat to support aggressive blood pressure lowering: the FEVER study.

Journal: Journal of hypertension 20051201

Title: The Felodipine Event Reduction (FEVER) Study: a randomized long-term placebo-controlled trial in Chinese hypertensive patients.

Journal: Journal of hypertension 20051201

Title: Calcium channel antagonists and inhibition of human sphincter of Oddi contractions.

Journal: Scandinavian journal of gastroenterology 20051201

Title: Impact of the intragastric location of extended release tablets on food interactions.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20051128

Title: Felodipine-metoprolol combination tablet: maintained health-related quality of life in the presence of substantial blood pressure reduction.

Journal: American journal of hypertension 20051001

Title: Modeling K(m) values using electrotopological state: substrates for cytochrome P450 3A4-mediated metabolism.

Journal: Bioorganic & medicinal chemistry letters 20050915

Title: Improved physicochemical characteristics of felodipine solid dispersion particles by supercritical anti-solvent precipitation process.

Journal: International journal of pharmaceutics 20050914

Title: Dihydropyridines, felodipine, and PHARMAC.

Journal: The New Zealand medical journal 20050715

Title: Felodipine-influenced gingival enlargement in an uncontrolled type 2 diabetic patient.

Journal: Journal of periodontology 20050701

Title: Miscibility behavior and formation mechanism of stabilized felodipine-polyvinylpyrrolidone amorphous solid dispersions.

Journal: Drug development and industrial pharmacy 20050701

Title: Prediction of genotoxicity of chemical compounds by statistical learning methods.

Journal: Chemical research in toxicology 20050601

Title: Renoprotective therapy: is it blood pressure or albuminuria that matters?

Journal: Lancet (London, England) 20050301

Title: Blood-pressure control for renoprotection in patients with non-diabetic chronic renal disease (REIN-2): multicentre, randomised controlled trial.

Journal: Lancet (London, England) 20050301

Title: [The effect and mechanism of felodipine and valsartan on a novel salt-sensitive hypertensive rat induced by sensory denervation].

Journal: Zhonghua xin xue guan bing za zhi 20050301

Title: Characteristics of felodipine-located poly(epsilon-caprolactone) microspheres.

Journal: Journal of microencapsulation 20050301

Title: Comparison of the effects of valsartan and felodipine on plasma leptin and insulin sensitivity in hypertensive obese patients.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension 20050301

Title: Drug interactions with grapefruit juice.

Journal: Obstetrics and gynecology 20050201

Title: Felodipine quantification in human plasma by high-performance liquid chromatography coupled to tandem mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050125

Title: Effect of menthol on the pharmacokinetics and pharmacodynamics of felodipine in healthy subjects.

Journal: European journal of clinical pharmacology 20050101

Title: Examination of 209 drugs for inhibition of cytochrome P450 2C8.

Journal: Journal of clinical pharmacology 20050101

Title: Retrospective evaluation of a possible interaction between warfarin and levofloxacin.

Journal: Pharmacotherapy 20050101

Title: [Toxicological analysis of selected 1,4-dihydropyridine calcium channel blockers in the diagnosis of intoxications].

Journal: Archiwum medycyny sadowej i kryminologii 20050101

Title: Urinary excretion of aquaporin-2 after furosemide and felodipine in healthy humans.

Journal: Scandinavian journal of clinical and laboratory investigation 20050101

Title: Ramipril/felodipine extended-release fixed-dose combination: a review of its use in the management of essential hypertension.

Journal: Drugs 20050101

Title: Drug-associated gingival enlargement: case report and review of aetiology, management and evidence-based outcomes of treatment.

Journal: Journal of the New Zealand Society of Periodontology 20050101

Title: Bergamottin contribution to the grapefruit juice-felodipine interaction and disposition in humans.

Journal: Clinical pharmacology and therapeutics 20041201

Title: The effect of global brain ischemia in normal and diabetic animals: the influence of calcium channel blockers.

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Title: 6'7'-Dihydroxybergamottin contributes to the grapefruit juice effect.

Journal: Clinical pharmacology and therapeutics 20040601

Title: Nelfinavir and felodipine: a cytochrome P450 3A4-mediated drug interaction.

Journal: Clinical pharmacology and therapeutics 20040401

Title: The effect of Ca2+ channel antagonists on plasma concentrations of matrix metalloproteinase-2 and -9 in essential hypertension.

Journal: American journal of hypertension 20040301

Title: Oxidation of Hantzsch 1,4-dihydropyridines of pharmacological significance by electrogenerated superoxide.

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Title: Adherence to calcium channel blocker therapy in older adults: a comparison of amlodipine and felodipine.

Journal: The Journal of international medical research 20040101

Title: [Efficacy and tolerability of felodipine based antihypertensive therapy in hospitalized patients with hypertension].

Journal: Kardiologiia 20040101

Title: Calcium channel blockers (felodipine) and pediatric essential hypertension.

Journal: Current hypertension reports 20031201

Title: Evaluation of a therapeutic conversion from amlodipine to felodipine.

Journal: Pharmacotherapy 20031101

Title: Multisite kinetic analysis of interactions between prototypical CYP3A4 subgroup substrates: midazolam, testosterone, and nifedipine.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20030901

Title: Evaluation of polar lipid-hydrophilic polymer microparticles.

Journal: International journal of pharmaceutics 20030827

Title: A comparative analysis of amlodipine and felodipine in a military outpatient population: efficacy, outcomes, and cost considerations.

Journal: Military medicine 20030701

Title: Clinical trial of extended-release felodipine in pediatric essential hypertension.

Journal: Pediatric nephrology (Berlin, Germany) 20030601

Title: Oxidized LDL and its compound lysophosphatidylcholine potentiate AngII-induced vasoconstriction by stimulation of RhoA.

Journal: Journal of the American Society of Nephrology : JASN 20030601

Title: Bergamottin, lime juice, and red wine as inhibitors of cytochrome P450 3A4 activity: comparison with grapefruit juice.

Journal: Clinical pharmacology and therapeutics 20030601

Title: Health economics in the Hypertension Optimal Treatment (HOT) study: costs and cost-effectiveness of intensive blood pressure lowering and low-dose aspirin in patients with hypertension.

Journal: Journal of internal medicine 20030401

Title: Can the USP paddle method be used to represent in-vivo hydrodynamics?

Journal: The Journal of pharmacy and pharmacology 20030401

Title: Short-versus long-term effects of different dihydropyridines on sympathetic and baroreflex function in hypertension.

Journal: Hypertension (Dallas, Tex. : 1979) 20030301

Title: [The effect of analysed hypotensive drugs on certain metabolic parameters].

Journal: Polskie Archiwum Medycyny Wewnetrznej 20030301

Title: Sensitive spectrophotometric determination of amlodipine and felodipine using iron(III) and ferricyanide.

Journal: Farmaco (Societa chimica italiana : 1989) 20030201

Title: [Dangerous duo: hypertension and pre-diabetes--the underestimated risk].

Journal: MMW Fortschritte der Medizin 20030123

Title: Different drug classes have variable effects on blood pressure depending on the time of day.

Journal: American journal of hypertension 20030101

Title: The effect of nonsteroidal anti-inflammatory drugs on blood pressure in patients treated with different antihypertensive drugs.

Journal: Journal of clinical hypertension (Greenwich, Conn.) 20030101

Title: In vitro release of felodipine from original brand and generic products.

Journal: Arzneimittel-Forschung 20030101

Title: Comparative effect of lercanidipine, felodipine, and nifedipine GITS on blood pressure and heart rate in patients with mild to moderate arterial hypertension: the Lercanidipine in Adults (LEAD) Study.

Journal: Journal of clinical hypertension (Greenwich, Conn.) 20030101

Title: [Severe felodipine and theophylline poisoning successfully treated by 4-aminopyridine: a case report].

Journal: Przeglad lekarski 20030101

Title: Chitosan microparticle preparation for controlled drug release by response surface methodology.

Journal: Journal of microencapsulation 20030101

Title: Safety and efficacy of therapeutically equivalent doses of sustained-release formulations of isradipine and felodipine.

Journal: Congestive heart failure (Greenwich, Conn.) 20030101

Title: Pharmacodynamic interactions of levosimendan and felodipine in patients with coronary heart disease.

Journal: Cardiovascular drugs and therapy 20030101

Title: Differential effects of once-daily antihypertensive drugs on blood pressure, left ventricular mass and sympathetic activity: Nifedipine-GITS versus felodipine-ER versus enalapril.

Journal: The Canadian journal of cardiology 20021201

Title: Effects of aging and AT-1 receptor blockade on NO synthase expression and renal function in SHR.

Journal: Biochimica et biophysica acta 20021021

Title: Evaluation of controlled-release polar lipid microparticles.

Journal: International journal of pharmaceutics 20020905

Title: Evaluation of peppermint oil and ascorbyl palmitate as inhibitors of cytochrome P4503A4 activity in vitro and in vivo.

Journal: Clinical pharmacology and therapeutics 20020901

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Journal: Journal of the American College of Cardiology 20020821

Title: Dihydropyridines are not substitutable without careful monitoring.

Journal: South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 20020801

Title: [The effect and mechanism of felodipine on monocrotaline induced pulmonary hypertension in rats].

Journal: Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20020801

Title: Angiotensin II type 1 receptor antagonism improves hypercholesterolemia-associated endothelial dysfunction.

Journal: Arteriosclerosis, thrombosis, and vascular biology 20020701

Title: A comparison of candesartan, felodipine, and their combination in the treatment of elderly patients with systolic hypertension.

Journal: American journal of hypertension 20020601

Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

Journal: The Journal of biological chemistry 20020419

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Journal: American heart journal 20020401

Title: Unmasking the dynamic interplay between intestinal P-glycoprotein and CYP3A4.

Journal: The Journal of pharmacology and experimental therapeutics 20020301

Title: Calcium channel blockade with felodipine does not affect metabolic coronary vasodilation in patients with coronary artery disease.

Journal: Journal of cardiovascular pharmacology 20020201

Title: A stability indicating LC method for felodipine.

Journal: Journal of pharmaceutical and biomedical analysis 20020201

Title: Enantioselective determination of felodipine in human plasma by chiral normal-phase liquid chromatography and electrospray ionisation mass spectrometry.

Journal: Journal of pharmaceutical and biomedical analysis 20020115

Title: Effect of felodipine on tacrolimus pharmacokinetics in a renal transplant recipient.

Journal: Transplantation 20020115

Title: Felodipine inhibits nuclear translocation of p42/44 mitogen-activated protein kinase and human smooth muscle cell growth.

Journal: Cardiovascular research 20020101

Title: Cutaneous drug reaction case reports: from the world literature.

Journal: American journal of clinical dermatology 20020101

Title: Influence of hydrodynamics and particle size on the absorption of felodipine in labradors.

Journal: Pharmaceutical research 20020101

Title: [Prospects of use of the combined preparation logimax in patients with essential hypertension].

Journal: Terapevticheskii arkhiv 20020101

Title: Efficacy and safety of barnidipine compared with felodipine in the treatment of hypertension in Chinese patients.

Journal: The Journal of international medical research 20020101

Title: IgA nephropathy in a patient with polycythemia vera. Clinical manifestation of chronic renal failure and heavy proteinuria.

Journal: American journal of nephrology 20020101

Title: Smooth blood pressure control obtained with extended-release felodipine in elderly patients with hypertension: evaluation by 24-hour ambulatory blood pressure monitoring.

Journal: Drugs & aging 20020101

Title: Preparation and characterization of drug-loaded polymethacrylate microspheres by an emulsion solvent evaporation method.

Journal: Journal of microencapsulation 20020101

Title: Influence of antihypertensive treatment with perindopril, pindolol or felodipinon plasma leptin concentration in patients with essential hypertension.

Journal: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20020101

Title: Deleterious effects of nifedipine on smooth muscle cells implies alterations of intracellular calcium signaling.

Journal: Fundamental & clinical pharmacology 20011201

Title: The effects of an ACE inhibitor and a calcium antagonist on the progression of renal disease: the Nephros Study.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20011101

Title: One-year study of felodipine or placebo for stage 1 isolated systolic hypertension.

Journal: Hypertension (Dallas, Tex. : 1979) 20011101

Title: Photodistributed felodipine-induced facial telangiectasia.

Journal: Journal of the American Academy of Dermatology 20010801

Title: Efficacy and safety of a therapeutic interchange from high-dose calcium channel blockers to a fixed-dose combination of amlodipine/benazepril in patients with moderate-to-severe hypertension.

Journal: Journal of human hypertension 20010801

Title: Reduction in diastolic blood pressure and cardiovascular mortality in nondiabetic hypertensive patients. A reanalysis of the HOT study.

Journal: Arquivos brasileiros de cardiologia 20010801

Title: Polymorphism of racemic felodipine and the unusual series of solid solutions in the binary system of its enantiomers.

Journal: Journal of pharmaceutical sciences 20010701

Title: [Felodipine in hypertensive patients with mild encephalopathies].

Journal: Deutsche medizinische Wochenschrift (1946) 20010511

Title: Investigation of the felodipine glassy state by atomic force microscopy.

Journal: International journal of pharmaceutics 20010507

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Journal: The American journal of cardiology 20010315

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Journal: Drug development and industrial pharmacy 20010201

Title: Seville orange juice-felodipine interaction: comparison with dilute grapefruit juice and involvement of furocoumarins.

Journal: Clinical pharmacology and therapeutics 20010101

Title: Comparison of the time courses and potencies of the vasodilator effects of nifedipine and felodipine in the human forearm.

Journal: Blood pressure 20010101

Title: A randomised trial to compare the efficacy and safety of Felodipine (Plendil) and Nifedipine (Adalat) retard in patients with mild-to-moderate hypertension.

Journal: West African journal of medicine 20010101

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Journal: The Journal of emergency medicine 20001101

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Journal: Drugs & aging 20000301

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Journal: International journal of clinical practice 19980901

Title: Significance of blood pressure levels achieved with felodipine anti-hypertensive treatment on cardiovascular structure and function changes.

Journal: Journal of human hypertension 19980701

Title: A comparison of nisoldipine coat-core and felodipine in the treatment of mild-to-moderate hypertension.

Journal: International journal of clinical practice 19980601

Title: Benazepril versus felodipine as supplement to bendroflumethiazide: evaluation by office and ambulatory blood pressure.

Journal: Blood pressure monitoring 19980401

Title: Prevention of left ventricular hypertrophy by ACE-inhibitor, ramipril in comparison with calcium-channel antagonist, felodipine.

Journal: International journal of cardiology 19980131

Title: Influence of felodipine on experimental seizures and activity of different antiepileptic drugs in mice.

Journal: Polish journal of pharmacology 19980101

Title: Effect of the calcium antagonist felodipine as supplementary vasodilator therapy in patients with chronic heart failure treated with enalapril: V-HeFT III. Vasodilator-Heart Failure Trial (V-HeFT) Study Group.

Journal: Circulation 19970805

Title: Verapamil accelerates the transition to heart failure in obese, hypertensive, female SHHF/Mcc-fa(cp) rats.

Journal: Journal of cardiovascular pharmacology 19970601

Title: Cardiovascular effects of a low-dose combination of ramipril and felodipine in spontaneously hypertensive rats.

Journal: British journal of pharmacology 19970501

Title: Calcium antagonists, a useful additional therapy in treatment resistant hypertension: comparison of felodipine ER and nifedipine Retard by 24-h ambulatory blood pressure monitoring.

Journal: The Netherlands journal of medicine 19970101

Title: Felodipine in the treatment of severe refractory hypertension.

Journal: Journal of human hypertension 19960901

Title: Losartan potassium: a review of its pharmacology, clinical efficacy and tolerability in the management of hypertension.

Journal: Drugs 19960501

Title: Does prophylactic treatment with felodipine, a calcium antagonist, prevent low-osmolar contrast-induced renal dysfunction in hydrated diabetic and nondiabetic patients with normal or moderately reduced renal function?

Journal: Scandinavian journal of urology and nephrology 19960201

Title: Global efficacy and tolerability of losartan, an angiotensin II subtype 1-receptor antagonist, in the treatment of hypertension.

Journal: Blood pressure. Supplement 19960101

Title: Safety and tolerability of losartan compared with atenolol, felodipine and angiotensin converting enzyme inhibitors.

Journal: Journal of hypertension. Supplement : official journal of the International Society of Hypertension 19950701

Title: Safety and tolerability of losartan potassium, an angiotensin II receptor antagonist, compared with hydrochlorothiazide, atenolol, felodipine ER, and angiotensin-converting enzyme inhibitors for the treatment of systemic hypertension.

Journal: The American journal of cardiology 19950415

Title: Isradipine. An update of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy in the treatment of mild to moderate hypertension.

Journal: Drugs 19950401

Title: Mono- and combination therapy with felodipine or enalapril in elderly patients with systolic hypertension.

Journal: Blood pressure 19940301

Title: Efficacy and tolerability of extended-release felodipine and extended-release nifedipine in patients with mild-to-moderate essential hypertension.

Journal: Clinical therapeutics 19940101

Title: Comparison of effects of felodipine versus hydrochlorothiazide on arterial diameter and pulse-wave velocity in essential hypertension.

Journal: The American journal of cardiology 19931001

Title: General toxicity of the new calcium antagonist felodipine in dogs.

Journal: Arzneimittel-Forschung 19930701

Title: A multicenter comparison of isradipine and felodipine in the treatment of mild-to-moderate hypertension. The Physician's Study Group.

Journal: American journal of hypertension 19930301

Title: Long-term effects of felodipine in patients with reduced renal function.

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Journal: Journal of cardiovascular pharmacology 19910601

Title: Felodipine in combination with a beta-adrenoceptor blocker as an effective substitute for triple therapy in severe hypertension. The Australian Felodipine Multicentre Study Group.

Journal: European journal of clinical pharmacology 19910101

Title: Extended release felodipine in essential hypertension. Variations in blood pressure during whole-day continuous ambulatory recording.

Journal: American journal of hypertension 19910101

Title: Acute effects on exercise tolerance of felodipine and diltiazem, alone and in combination, in stable effort angina.

Journal: European heart journal 19910101

Title: Felodipine ER formulation in the treatment of mild hypertension: efficacy and tolerability vs placebo.

Journal: British journal of clinical pharmacology 19901001

Title: The influence of infusion rate on the hemodynamic effects of felodipine.

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Journal: Cardiovascular drugs and therapy 19900601

Title: Cardiovascular-risk reduction: initial diuretic therapy compared with calcium-antagonist (felodipine) therapy for primary hypertension.

Journal: The Medical journal of Australia 19890904

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Journal: Drugs 19881001

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Journal: Journal of cardiovascular pharmacology 19880701

Title: A double-blind comparison of felodipine and hydrochlorothiazide added to metoprolol to control hypertension.

Journal: European journal of clinical pharmacology 19880101

Title: Catecholamines, renin-angiotensin-aldosterone, and cardiovascular response during exercise following acute and long-term calcium antagonism with felodipine in essential hypertension.

Journal: Journal of cardiovascular pharmacology 19871001

Title: Monotherapy with felodipine, a new calcium antagonist, in mild and moderate hypertension.

Journal: Journal of cardiovascular pharmacology 19870101

Title: Felodipine, a new calcium antagonist, as monotherapy in mild or moderate hypertension. Cooperative study group.

Journal: Drugs 19870101

Title: Baroreflex control of renin release in spontaneously hypertensive rats after administration of felodipine.

Journal: Drugs 19870101

Title: Felodipine compared to nifedipine as 'third-line drug' in resistant hypertension.

Journal: Angiology 19861101

Title: Renal and antihypertensive effects of felodipine in hypertensive patients.

Journal: Journal of hypertension. Supplement : official journal of the International Society of Hypertension 19851201

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Journal: Drugs 19850101

Title: Comparative trial of felodipine and nifedipine in refractory hypertension.

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Journal: Drugs 19850101

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Tags:72509-76-3 Molecular Formula|72509-76-3 MDL|72509-76-3 SMILES|72509-76-3 3-ethyl 5-methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate