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76676-34-1,MFCD00868595
Catalog No.:AA005VYV

76676-34-1 | RU 28318, potassium salt

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10mg
≥98%(HPLC)
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$425.00   $298.00
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50mg
≥98%(HPLC)
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$1,595.00   $1,117.00
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  • Technical Information
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  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA005VYV
Chemical Name:
RU 28318, potassium salt
CAS Number:
76676-34-1
Molecular Formula:
C21H29O
Molecular Weight:
297.4544
MDL Number:
MFCD00868595
SMILES:
CCC[C@@H]1CC2=CC(=O)CC[C]2[C@@H]2[C@@H]1[C@@H]1CC[C][C@]1(CC2)C
Properties
Computed Properties
 
Complexity:
733  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
7  
Heavy Atom Count:
30  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
5  

Literature

Title: Mineralocorticoid receptors in the medial prefrontal cortex and hippocampus mediate rats' unconditioned fear behaviour.

Journal: Hormones and behavior 20111101

Title: Blockade of mineralocorticoid and glucocorticoid receptors reverses stress-induced motor impairments.

Journal: Neuroendocrinology 20110101

Title: Corticosteroids operate as a switch between memory systems.

Journal: Journal of cognitive neuroscience 20100701

Title: Acute stress impairs hippocampal mossy fiber-CA3 long-term potentiation by enhancing cAMP-specific phosphodiesterase 4 activity.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20100601

Title: Mineralocorticoid receptor antagonism prevents hedonic deficits induced by a chronic sodium appetite.

Journal: Behavioral neuroscience 20100401

Title: Protein kinase D stabilizes aldosterone-induced ERK1/2 MAP kinase activation in M1 renal cortical collecting duct cells to promote cell proliferation.

Journal: The Journal of steroid biochemistry and molecular biology 20100101

Title: Glucocorticoid suppresses steroidogenesis in rat progenitor Leydig cells.

Journal: Journal of andrology 20100101

Title: Modulation of presynaptic glucocorticoid receptors on glutamate release from rat hippocampal nerve terminals.

Journal: Synapse (New York, N.Y.) 20090901

Title: Aldosterone rapidly activates protein kinase D via a mineralocorticoid receptor/EGFR trans-activation pathway in the M1 kidney CCD cell line.

Journal: The Journal of steroid biochemistry and molecular biology 20070101

Title: Dexamethasone induces cell death which may be blocked by NMDA receptor antagonists but is insensitive to Mg2+ in cerebellar granule neurons.

Journal: Brain research 20060127

Title: Stimulation of testosterone production in rat Leydig cells by aldosterone is mineralocorticoid receptor mediated.

Journal: Molecular and cellular endocrinology 20051124

Title: Disruption of mineralocorticoid receptor function increases corticosterone responding to a mild, but not moderate, psychological stressor.

Journal: American journal of physiology. Endocrinology and metabolism 20050601

Title: Glucocorticoid receptor blockade disinhibits pituitary-adrenal activity during the stress hyporesponsive period of the mouse.

Journal: Endocrinology 20050301

Title: Nongenomic effects of mineralocorticoid receptor activation in the cardiovascular system.

Journal: Steroids 20050101

Title: Mineralocorticoid receptor antagonism prevents the electrical remodeling that precedes cellular hypertrophy after myocardial infarction.

Journal: Circulation 20040817

Title: Central effects of mineralocorticoids on blood pressure: new answers, new questions.

Journal: Journal of hypertension 20020901

Title: Influence of sodium intake on the cardiovascular and renal effects of brain mineralocorticoid receptor blockade in normotensive rats.

Journal: Journal of hypertension 20020901

Title: Effects of brain mineralocorticoid receptor blockade on blood pressure and renal functions in DOCA-salt hypertension.

Journal: European journal of pharmacology 20020202

Title: Acute exposure to a novel stressor further reduces the habituated corticosterone response to restraint in rats.

Journal: Stress (Amsterdam, Netherlands) 20011201

Title: Intracerebroventricular administration of a glucocorticoid receptor antagonist enhances the cardiovascular responses to brief restraint stress.

Journal: European journal of pharmacology 20011026

Title: Involvement of brain mineralocorticoid receptor in salt-enhanced hypertension in spontaneously hypertensive rats.

Journal: Hypertension (Dallas, Tex. : 1979) 20011001

Title: Psychological stress increases hippocampal mineralocorticoid receptor levels: involvement of corticotropin-releasing hormone.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20010701

Title: Glucocorticoid and mineralocorticoid receptors are involved in the facilitation of anxiety-like response induced by restraint.

Journal: Neuroendocrinology 20010401

Title: Endogenous glucocorticoids play a positive regulatory role in the anti-keyhole limpet hemocyanin in vivo antibody response.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20010315

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Tags:76676-34-1 Molecular Formula|76676-34-1 MDL|76676-34-1 SMILES|76676-34-1 RU 28318, potassium salt