Home Other Building Blocks 76684-89-4
76684-89-4,MFCD00132882
Catalog No.:AA00G32H

76684-89-4 | Loxistatin acid

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$89.00   $62.00
- +
5mg
95%
in stock  
$216.00   $151.00
- +
10mg
95%
in stock  
$259.00   $181.00
- +
25mg
95%
in stock  
$311.00   $218.00
- +
50mg
95%
in stock  
$374.00   $262.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00G32H
Chemical Name:
Loxistatin acid
CAS Number:
76684-89-4
Molecular Formula:
C15H26N2O5
Molecular Weight:
314.3773
MDL Number:
MFCD00132882
SMILES:
CC(CC(C(=O)NCCC(C)C)NC(=O)C1OC1C(=O)O)C
Properties

Downstream Synthesis Route

[1]Huang;McGowan;Detwiler[JournalofMedicinalChemistry,1992,vol.35,#11,p.2048-2054]

[1]Huang;McGowan;Detwiler[JournalofMedicinalChemistry,1992,vol.35,#11,p.2048-2054]

[1]Huang;McGowan;Detwiler[JournalofMedicinalChemistry,1992,vol.35,#11,p.2048-2054]

[1]Huang;McGowan;Detwiler[JournalofMedicinalChemistry,1992,vol.35,#11,p.2048-2054]

[1]Huang;McGowan;Detwiler[JournalofMedicinalChemistry,1992,vol.35,#11,p.2048-2054]

Literature

Title: Khan MS, et al. Design, synthesis, evaluation and thermodynamics of 1-substituted pyridylimidazo,5-apyridine derivatives as cysteine protease inhibitors. PLoS One. 2013 Aug 5;8(8):e69982.

Title: Toda G, et al. Calcium-activated neutral protease inhibitor (E-64c) and reperfusion for experimental myocardial infarction. Jpn Heart J. 1989 May;30(3):375-86.

Title: Radzey H, et al. E-64c-hydrazide: a lead structure for the development of irreversible cathepsin C inhibitors. ChemMedChem. 2013 Aug;8(8):1314-21.

Title: Ji Yeun Kim, et al. Safe, High-Throughput Screening of Natural Compounds of MERS-CoV Entry Inhibitors Using a Pseudovirus Expressing MERS-CoV Spike Protein. Int J Antimicrob Agents. 2018 Nov;52(5):730-732.

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