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Home Other Building Blocks 79965-10-9
79965-10-9,MFCD00870699
Catalog No.:AA008KO8

79965-10-9 | N-4-Methoxyphenylretinamide

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
2 weeks  
$1,929.00   $1,350.00
- +
25mg
2 weeks  
$4,225.00   $2,958.00
- +
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA008KO8
Chemical Name:
N-4-Methoxyphenylretinamide
CAS Number:
79965-10-9
Molecular Formula:
C27H35NO2
Molecular Weight:
405.5723
MDL Number:
MFCD00870699
SMILES:
COc1ccc(cc1)NC(=O)/C=C(/C=C/C=C(/C=C/C1=C(C)CCCC1(C)C)\C)\C
NSC Number:
743413
Properties
Computed Properties
 
Complexity:
741  
Covalently-Bonded Unit Count:
1  
Defined Bond Stereocenter Count:
4  
Heavy Atom Count:
30  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
7  
XLogP3:
7.6  

Literature

Title: Fenretinide derivatives act as disrupters of interactions of serum retinol binding protein (sRBP) with transthyretin and the sRBP receptor.

Journal: Journal of medicinal chemistry 20110714

Title: Characterization of the metabolism of fenretinide by human liver microsomes, cytochrome P450 enzymes and UDP-glucuronosyltransferases.

Journal: British journal of pharmacology 20110201

Title: Design and synthesis of 4-HPR derivatives for rhabdoid tumors.

Journal: Bioorganic & medicinal chemistry letters 20080701

Title: Solid phase-assisted synthesis and screening of a small library of N-(4-hydroxyphenyl)retinamide (4-HPR) analogs.

Journal: Bioorganic & medicinal chemistry letters 20070201

Title: Chemoprevention of skin carcinogenesis by phenylretinamides: retinoid receptor-independent tumor suppression.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20060201

Title: Liquid chromatography method for quantifying N-(4-hydroxyphenyl)retinamide and N-(4-methoxyphenyl)retinamide in tissues.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040905

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