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80126-53-0,MFCD23135865
Catalog No.:AA00ID0M

80126-53-0 | L-2-Methylphenylalanine

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1g
95%
in stock  
$7.00   $5.00
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5g
95%
in stock  
$33.00   $23.00
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10g
95%
in stock  
$64.00   $45.00
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25g
95%
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$158.00   $110.00
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  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00ID0M
Chemical Name:
L-2-Methylphenylalanine
CAS Number:
80126-53-0
Molecular Formula:
C10H13NO2
Molecular Weight:
179.2157
MDL Number:
MFCD23135865
SMILES:
OC(=O)C(Cc1ccccc1C)N
Properties
Computed Properties
 
Complexity:
182  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
13  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
3  
XLogP3:
-1.2  

Upstream Synthesis Route

[1]AdvancedSynthesisandCatalysis,2017,vol.359,#9,p.1570-1576

[1]JournalofLabelledCompoundsandRadiopharmaceuticals,2011,vol.54,#2,p.80-85

[1]JournaloftheAmericanChemicalSociety,2015,vol.137,#40,p.12977-12983

[1]JournaloftheAmericanChemicalSociety,2015,vol.137,#40,p.12977-12983

[1]JournalofOrganicChemistry,2009,vol.74,#23,p.9152-9157

Downstream Synthesis Route
2-Oxo-3-o-tolyl-propionicacidanion 
  80126-53-0 

[1]TetrahedronLetters,1987,vol.28,p.3745-3746

80126-53-0   
(R)-3-amino-3-(2-methylphenyl)propionicacid 

[1]JournaloftheAmericanChemicalSociety,2007,vol.129,p.6988-6989

[1]JournalofMedicinalChemistry,2007,vol.50,p.2753-2766

[1]JournalofMedicinalChemistry,2007,vol.50,p.2753-2766

80126-53-0   
C19H23N3O2*HCl 

[1]JournalofMedicinalChemistry,2007,vol.50,p.2753-2766

Literature

Title: Preparative separation and identification of derivatized beta-methylphenylalanine enantiomers by chiral SFC, HPLC and NMR for development of new peptide ligand mimetics in drug discovery.

Journal: Journal of pharmaceutical and biomedical analysis 20060303

Title: Discovery of potent, selective, and orally bioavailable pyridone-based dipeptidyl peptidase-4 inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20060301

Title: Discovery of potent and selective phenylalanine based dipeptidyl peptidase IV inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20050516

Title: Modifications to the N-terminus but not the C-terminus of calcitonin gene-related peptide(8-37) produce antagonists with increased affinity.

Journal: Journal of medicinal chemistry 20030605

Title: Magnesium and biological activity of oxytocin analogues modified on aromatic ring of amino acid in position 2.

Journal: Journal of peptide science : an official publication of the European Peptide Society 20010801

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SDS
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