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80573-04-2,MFCD00868204
Catalog No.:AA0052D9

80573-04-2 | Balsalazide

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5mg
95%
in stock  
$67.00   $47.00
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10mg
95%
in stock  
$124.00   $87.00
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25mg
95%
in stock  
$272.00   $190.00
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100mg
95%
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$815.00   $570.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA0052D9
Chemical Name:
Balsalazide
CAS Number:
80573-04-2
Molecular Formula:
C17H15N3O6
Molecular Weight:
357.3175
MDL Number:
MFCD00868204
SMILES:
OC(=O)CCNC(=O)c1ccc(cc1)/N=N/c1ccc(c(c1)C(=O)O)O
Properties
Properties
 
Form:
Solid  
MP:
254-255 °C  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
545  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
26  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
7  
XLogP3:
2.2  

Downstream Synthesis Route

[1]CurrentPatentAssignee:CHINAPHARMACEUTICALUNIVERSITY-CN107296794,2017,ALocationinpatent:Paragraph0113-0115

Literature

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Title: Effect of sulphasalazine and balsalazide on histamine release from mast cells.

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Title: Treatment of ulcerative colitis with oral mesalamine: advances in drug formulation, efficacy expectations and dose response, compliance, and chemoprevention.

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Journal: PloS one 20060101

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Title: Low-dose balsalazide plus a high-potency probiotic preparation is more effective than balsalazide alone or mesalazine in the treatment of acute mild-to-moderate ulcerative colitis.

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Title: Low dose balsalazide (1.5 g twice daily) and mesalazine (0.5 g three times daily) maintained remission of ulcerative colitis but high dose balsalazide (3.0 g twice daily) was superior in preventing relapses.

Journal: Gut 20011201

Title: Leucopenia resulting from a drug interaction between azathioprine or 6-mercaptopurine and mesalamine, sulphasalazine, or balsalazide.

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Title: Kruis W, et al. Low dose balsalazide (1.5 g twice daily) and mesalazine (0.5 g three times daily) maintained remission of ulcerative colitis but high dose balsalazide (3.0 g twice daily) was superior in preventing relapses. Gut, 2001. 49(6): p. 783-789.

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SDS
Tags:80573-04-2 Molecular Formula|80573-04-2 MDL|80573-04-2 SMILES|80573-04-2 Balsalazide