Home Amines 15663-27-1
15663-27-1,MFCD00011623
Catalog No.:AA0034JI

15663-27-1 | dichloroplatinum diamine

Pack Size
Purity
Availability
Price(USD)
Quantity
  
100mg
95
in stock  
$56.00   $40.00
- +
250mg
99%
in stock  
$91.00   $64.00
- +
1g
99%
in stock  
$110.00   $77.00
- +
5g
95%
in stock  
$542.00   $379.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0034JI
Chemical Name:
dichloroplatinum diamine
CAS Number:
15663-27-1
Molecular Formula:
Cl2H6N2Pt++
Molecular Weight:
300.0450
MDL Number:
MFCD00011623
SMILES:
Cl[Pt+2]Cl.N.N
Properties
Properties
 
Form:
Solid  
MP:
340 °C (dec.)(lit.)  
Solubility:
Soluble in DMF. Insoluble in most common solvents  
Storage:
Inert atmosphere;2-8℃;  


Literature

Title: Wang X, et al. Requirement for ERK activation in cisplatin-induced apoptosis. J Biol Chem. 2000 Dec 15;275(50):39435-43.

Title: Cummings BS, et al. Cisplatin-induced renal cell apoptosis: caspase 3-dependent and -independent pathways. J Pharmacol Exp Ther. 2002 Jul;302(1):8-17.

Title: Park HR, et al. Enhanced antitumor efficacy of cisplatin in combination with HemoHIM in tumor-bearing mice. BMC Cancer. 2009 Mar 17;9:85.

Title: Shimeda Y, et al. Protective effects of capsaicin against cisplatin-induced nephrotoxicity in rats. Biol Pharm Bull. 2005 Sep;28(9):1635-8.

Title: Hall MD, et al. Say no to DMSO: dimethylsulfoxide inactivates cisplatin, NSC 241240, and other platinum complexes. Cancer Res. 2014 Jul 15;74(14):3913-22.

Title: Wu K, et al. Cisplatin inhibits the progression of bladder cancer by selectively depleting G-MDSCs: A novel chemoimmunomodulating strategy. Clin Immunol. 2018 Aug;193:60-69.

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