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81-23-2,MFCD00066410
Catalog No.:AA0036EL

81-23-2 | Dehydrocholic acid

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100mg
99%(HPLC)powder
in stock  
$43.00   $30.00
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1g
≥95%
in stock  
$46.00   $32.00
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5g
≥95%
in stock  
$133.00   $93.00
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10g
98.5%
in stock  
$182.00   $128.00
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25g
95%
in stock  
$411.00   $288.00
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50g
98.5%
in stock  
$557.00   $390.00
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100g
98.5%
in stock  
$986.00   $690.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0036EL
Chemical Name:
Dehydrocholic acid
CAS Number:
81-23-2
Molecular Formula:
C24H34O5
Molecular Weight:
402.5238
MDL Number:
MFCD00066410
SMILES:
OC(=O)CC[C@H]([C@H]1CC[C@@H]2[C@]1(C)C(=O)C[C@H]1[C@H]2C(=O)C[C@H]2[C@]1(C)CCC(=O)C2)C
NSC Number:
8796
Properties
Properties
 
BP:
581.5 °C at 760 mmHg  
Form:
Solid  
MP:
238-240 °C  
Refractive Index:
30.5 ° (C=2, Dioxane)  
Solubility:
ethanol: 10 mg/mL  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
756  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
8  
Heavy Atom Count:
29  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
4  
XLogP3:
2.6  

Literature

Title: Novel whole-cell biocatalysts with recombinant hydroxysteroid dehydrogenases for the asymmetric reduction of dehydrocholic acid.

Journal: Applied microbiology and biotechnology 20120901

Title: Biophysical investigations into the interactions of endotoxins with bile acids.

Journal: Innate immunity 20120401

Title: Discovery of an entropically-driven small molecule streptavidin binder from nucleic acid-encoded libraries.

Journal: Organic & biomolecular chemistry 20120227

Title: Preparation and characterization of uniform drug particles: dehydrocholic acid.

Journal: Journal of colloid and interface science 20120215

Title: Using functional signatures to identify repositioned drugs for breast, myelogenous leukemia and prostate cancer.

Journal: PLoS computational biology 20120201

Title: The role of the acquisition methods in the analysis of natural and synthetic steroids and cholic acids by gas chromatography-mass spectrometry.

Journal: Journal of chromatography. A 20111111

Title: Improvement of oxaprozin solubility and permeability by the combined use of cyclodextrin, chitosan, and bile components.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20110801

Title: Identification, cloning, heterologous expression, and characterization of a NADPH-dependent 7β-hydroxysteroid dehydrogenase from Collinsella aerofaciens.

Journal: Applied microbiology and biotechnology 20110401

Title: Differentiation of various traditional Chinese medicines derived from animal bile and gallstone: simultaneous determination of bile acids by liquid chromatography coupled with triple quadrupole mass spectrometry.

Journal: Journal of chromatography. A 20110107

Title: Ursodeoxycholic acid is conjugated with taurine to promote secretin-stimulated biliary hydrocholeresis in the normal rat.

Journal: PloS one 20110101

Title: Chemical genetic screen identifies lithocholic acid as an anti-aging compound that extends yeast chronological life span in a TOR-independent manner, by modulating housekeeping longevity assurance processes.

Journal: Aging 20100701

Title: Thermodynamic and elastic fluctuation analysis of Langmuir mixed monolayers composed by dehydrocholic acid (HDHC) and didodecyldimethylammonium bromide (DDAB).

Journal: Colloids and surfaces. B, Biointerfaces 20100101

Title: Surgical outcome in relation to duct size at the porta hepatis and the use of cholagogues in patients with biliary atresia.

Journal: Tropical gastroenterology : official journal of the Digestive Diseases Foundation 20100101

Title: Study on bioactive compounds of in vitro cultured Calculus Suis and natural Calculus Bovis.

Journal: Animal science journal = Nihon chikusan Gakkaiho 20091201

Title: Protective effect of bile acid derivatives in phalloidin-induced rat liver toxicity.

Journal: Toxicology and applied pharmacology 20090815

Title: Acidic and basic solutions dissolve protein plugs made of lithostathine complicating choledochal cyst/pancreaticobiliary maljunction.

Journal: Digestive diseases and sciences 20090701

Title: Spread mixed monolayers of deoxycholic and dehydrocholic acids at the air-water interface, effect of subphase pH. Characterization by axisymmetric drop shape analysis.

Journal: Biophysical chemistry 20080101

Title: Magnetic resonance cholangiopancreatography: potential usefulness of dehydrocholic acid (DHCA) administration in the evaluation of anastomotic site.

Journal: Hepato-gastroenterology 20080101

Title: Magnetic resonance cholangiopancreatography: potential usefulness of dehydrocholic acid (DHCA) administration in the evaluation of biliary disease.

Journal: Hepato-gastroenterology 20080101

Title: A new approach for diagnosis of hepatolithiasis: magnetic resonance cholangiopancreatography: potential usefulness of dehydrocholic acid (DHCA) administration in the evaluation of hepatolithiasis.

Journal: Hepato-gastroenterology 20080101

Title: Aqueous sodium dehydrocholate-sodium deoxycholate mixtures at low concentration.

Journal: Journal of colloid and interface science 20071015

Title: Determination of critical micellar concentrations of cholic acid and its keto derivatives.

Journal: Colloids and surfaces. B, Biointerfaces 20071001

Title: Regio- and stereoselective reductions of dehydrocholic acid.

Journal: Steroids 20060601

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Bile acids directly augment caudal related homeobox gene Cdx2 expression in oesophageal keratinocytes in Barrett's epithelium.

Journal: Gut 20060101

Title: A novel insulin derivative chemically modified with dehydrocholic acid: synthesis, characterization and biological activity.

Journal: Biotechnology and applied biochemistry 20050801

Title: Sterol-derived hormone(s) controls entry into diapause in Caenorhabditis elegans by consecutive activation of DAF-12 and DAF-16.

Journal: PLoS biology 20041001

Title: Lasting blood-brain barrier disruption induces epileptic focus in the rat somatosensory cortex.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20040908

Title: Choleretic activity and biliary elimination of lipids and bile acids induced by an artichoke leaf extract in rats.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20021201

Title: Spasmocanulase in irritable bowel syndrome.

Journal: Saudi medical journal 20020901

Title: Carbonic anhydrase inhibitors. Preparation of potent sulfonamides inhibitors incorporating bile acid tails.

Journal: Bioorganic & medicinal chemistry letters 20020617

Title: Choledocholithiasis in an infant of extremely low birthweight.

Journal: Journal of paediatrics and child health 20020401

Title: Anodic electrochemical oxidation of cholic acid.

Journal: Steroids 20010201

Title: Estradiol-17 beta-D-glucuronide (E-17G) cholestasis in perfused rat liver: fate of E-17G and choleretic responses to bile salts.

Journal: Hepatology (Baltimore, Md.) 19900501

Title: 3 beta-Hydroxysteroid dehydrogenase of Ruminococcus sp. from human intestinal bacteria.

Journal: Journal of biochemistry 19860501

Title: Cholestasis induced by estradiol-17 beta-D-glucuronide: mechanisms and prevention by sodium taurocholate.

Journal: Hepatology (Baltimore, Md.) 19840101

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Tags:81-23-2 Molecular Formula|81-23-2 MDL|81-23-2 SMILES|81-23-2 Dehydrocholic acid