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81907-62-2,MFCD26131275
Catalog No.:AA00G334

81907-62-2 | Ganoderic acid A

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1mg
98%
in stock  
$152.00   $107.00
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5mg
≥95%
in stock  
$226.00   $158.00
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10mg
≥95%
in stock  
$382.00   $267.00
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25mg
≥95%
in stock  
$842.00   $589.00
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50mg
≥95%
in stock  
$1,455.00   $1,018.00
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1000mg
98% by HPLC
in stock  
$23,325.00   $16,327.00
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00G334
Chemical Name:
Ganoderic acid A
CAS Number:
81907-62-2
Molecular Formula:
C30H44O7
Molecular Weight:
516.6662
MDL Number:
MFCD26131275
SMILES:
O=C(C[C@H](C(=O)O)C)C[C@H]([C@H]1C[C@@H]([C@@]2([C@]1(C)CC(=O)C1=C2[C@@H](O)CC2[C@]1(C)CCC(=O)C2(C)C)C)O)C
Properties
Computed Properties
 
Complexity:
1070  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
9  
Heavy Atom Count:
37  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
6  
XLogP3:
2.2  

Literature

Title: Ganoderic Acid A improves high fat diet-induced obesity, lipid accumulation and insulin sensitivity through regulating SREBP pathway.

Journal: Chemico-biological interactions 20180625

Title: Structure-activity relationships of ganoderma acids from Ganoderma lucidum as aldose reductase inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20111215

Title: Sensitive and selective liquid chromatography-tandem mass spectrometry method for the determination of five ganoderic acids in Ganoderma lucidum and its related species.

Journal: Journal of pharmaceutical and biomedical analysis 20110325

Title: Inhibition of aldose reductase in vitro by constituents of Ganoderma lucidum.

Journal: Planta medica 20101001

Title: Lanostane triterpenes from the fruiting bodies of Ganoderma lucidum and their inhibitory effects on adipocyte differentiation in 3T3-L1 Cells.

Journal: Journal of natural products 20100226

Title: 11beta-Hydroxysteroid dehydrogenase 1 inhibiting constituents from Eriobotrya japonica revealed by bioactivity-guided isolation and computational approaches.

Journal: Bioorganic & medicinal chemistry 20100215

Title: Development of a new method for improved identification and relative quantification of unknown metabolites in complex samples: determination of a triterpenoid metabolic fingerprint for the in situ characterization of Ganoderma bioactive compounds.

Journal: Journal of separation science 20091201

Title: Metabolism and pharmacokinetics in rats of ganoderiol F, a highly cytotoxic and antitumor triterpene from Ganoderma lucidum.

Journal: Journal of natural medicines 20090701

Title: Performance analyses of a pH-shift and DOT-shift integrated fed-batch fermentation process for the production of ganoderic acid and Ganoderma polysaccharides by medicinal mushroom Ganoderma lucidum.

Journal: Bioresource technology 20090301

Title: Ganoderic acids suppress growth and invasive behavior of breast cancer cells by modulating AP-1 and NF-kappaB signaling.

Journal: International journal of molecular medicine 20080501

Title: [Chemical constituents of the spores of Ganoderma lucidum].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20080101

Title: Inhibition of oxidative stress-induced invasiveness of cancer cells by Ganoderma lucidum is mediated through the suppression of interleukin-8 secretion.

Journal: International journal of molecular medicine 20061001

Title: Anti-HIV-1 and anti-HIV-1-protease substances from Ganoderma lucidum.

Journal: Phytochemistry 19981101

Title: Triterpenes from the spores of Ganoderma lucidum and their inhibitory activity against HIV-1 protease.

Journal: Chemical & pharmaceutical bulletin 19981001

Title: Radwan FF et al. Reduction of myeloid-derived suppressor cells and lymphoma growth by a natural triterpenoid. J Cell Biochem. 2015 Jan;116(1):102-14.

Title: Yao X et al. Inhibition of the JAK-STAT3 signaling pathway by ganoderic acid A enhances chemosensitivity of HepG2 cells to cisplatin.Planta Med. 2012 Nov;78(16):1740-8.

Title: Gill BS et al. Evaluating anti-oxidant potential of ganoderic acid A in STAT 3 pathway in prostate cancer. Mol Biol Rep. 2016 Sep 17.

Title: Shao J et al. [Ganoderic acid A suppresses proliferation and invasion and induces apoptosis in human osteosarcoma cells Nan Fang Yi Ke Da Xue Xue Bao. 2015 May;35(5):619-24.

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Tags:81907-62-2 Molecular Formula|81907-62-2 MDL|81907-62-2 SMILES|81907-62-2 Ganoderic acid A