Home Fluorides 824-75-9
824-75-9,MFCD00007992
Catalog No.:AA003LC3

824-75-9 | 4-Fluorobenzamide

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5g
98%
in stock  
$6.00   $4.00
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25g
98%
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$13.00   $9.00
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100g
98%
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$46.00   $32.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003LC3
Chemical Name:
4-Fluorobenzamide
CAS Number:
824-75-9
Molecular Formula:
C7H6FNO
Molecular Weight:
139.1270
MDL Number:
MFCD00007992
SMILES:
NC(=O)c1ccc(cc1)F
NSC Number:
102765
Properties
Properties
 
BP:
253.1°C at 760 mmHg  
Form:
Solid  
MP:
154-157 °C(lit.)  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
130  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
10  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
1  
XLogP3:
0.9  

Literature

Title: Intranasally administered neuropeptide S (NPS) exerts anxiolytic effects following internalization into NPS receptor-expressing neurons.

Journal: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20120501

Title: Molecular evolution of the neuropeptide S receptor.

Journal: PloS one 20120101

Title: Metabolic stability of new anticonvulsants in body fluids and organ homogenates.

Journal: Acta poloniae pharmaceutica 20120101

Title: Synthesis and separation of the enantiomers of the neuropeptide S receptor antagonist (9R/S)-3-oxo-1,1-diphenyl-tetrahydro-oxazolo[3,4-a]pyrazine-7-carboxylic acid 4-fluoro-benzylamide (SHA 68).

Journal: Journal of medicinal chemistry 20110428

Title: The asthma candidate gene NPSR1 mediates isoform specific downstream signalling.

Journal: BMC pulmonary medicine 20110101

Title: Multiple polymorphisms affect expression and function of the neuropeptide S receptor (NPSR1).

Journal: PloS one 20110101

Title: Neurobiology, pharmacology, and medicinal chemistry of neuropeptide S and its receptor.

Journal: Medicinal research reviews 20100901

Title: 4-Substituted-7-N-alkyl-N-acetyl 2-aminobenzothiazole amides: drug-like and non-xanthine based A2B adenosine receptor antagonists.

Journal: Bioorganic & medicinal chemistry letters 20100715

Title: Further studies on the pharmacological profile of the neuropeptide S receptor antagonist SHA 68.

Journal: Peptides 20100501

Title: Importance of extracellular loop one of the neuropeptide S receptor for biogenesis and function.

Journal: Peptides 20100101

Title: Extended use of raltegravir in the treatment of HIV-1 infection: optimizing therapy.

Journal: Infection and drug resistance 20100101

Title: Design, synthesis, and preliminary in vitro and in vivo evaluation of N-(2-diethylaminoethyl)-4-[18F]fluorobenzamide ([18F]-DAFBA): a novel potential PET probe to image melanoma tumors.

Journal: Bioconjugate chemistry 20090318

Title: Synthesis and pharmacological in vitro and in vivo profile of 3-oxo-1,1-diphenyl-tetrahydro-oxazolo[3,4-a]pyrazine-7-carboxylic acid 4-fluoro-benzylamide (SHA 68), a selective antagonist of the neuropeptide S receptor.

Journal: The Journal of pharmacology and experimental therapeutics 20080601

Title: Raltegravir: first in class HIV integrase inhibitor.

Journal: Therapeutics and clinical risk management 20080401

Title: [New derivatives of eremomycin containing (15)n or f atoms for NMR study].

Journal: Bioorganicheskaia khimiia 20080101

Title: Raltegravir in the management of HIV-infected patients.

Journal: Drug design, development and therapy 20080101

Title: From dihydroxypyrimidine carboxylic acids to carboxamide HIV-1 integrase inhibitors: SAR around the amide moiety.

Journal: Bioorganic & medicinal chemistry letters 20070115

Title: 19F NMR chemical shifts induced by a helical peptide.

Journal: Chembiochem : a European journal of chemical biology 20060701

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: A series of 5-(5,6)-dihydrouracil substituted 8-hydroxy-[1,6]naphthyridine-7-carboxylic acid 4-fluorobenzylamide inhibitors of HIV-1 integrase and viral replication in cells.

Journal: Bioorganic & medicinal chemistry letters 20051015

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