Home Sulfonamines 829-71-0
829-71-0,MFCD00837255
Catalog No.:AA01A6S7

829-71-0 | 4-(2-hydroxyethyl)benzene-1-sulfonamide

Pack Size
Purity
Availability
Price(USD)
Quantity
  
100mg
95%
1 week  
$173.00   $121.00
- +
250mg
95%
1 week  
$292.00   $205.00
- +
1g
95%
1 week  
$786.00   $550.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA01A6S7
Chemical Name:
4-(2-hydroxyethyl)benzene-1-sulfonamide
CAS Number:
829-71-0
Molecular Formula:
C8H11NO3S
Molecular Weight:
201.2428
MDL Number:
MFCD00837255
SMILES:
OCCc1ccc(cc1)S(=O)(=O)N
Properties
Computed Properties
 
Complexity:
237  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
13  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
3  
XLogP3:
0.1  

Downstream Synthesis Route
23911-25-3    829-71-0   
{(2-{carboxymethyl-2-(4-sulfamoyl-phenyl)-ethoxycarbonylmethyl-amino}-ethyl)-2-(4-sulfamoyl-phenyl)-ethoxycarbonylmethyl-amino}-aceticacid 

[1]JournalofMedicinalChemistry,2002,vol.45,p.1466-1476

139-13-9    829-71-0   
{carboxymethyl-2-(4-sulfamoyl-phenyl)-ethoxycarbonylmethyl-amino}-aceticacid 

[1]Scozzafava,Andrea;Menabuoni,Luca;Mincione,Francesco;Supuran,ClaudiuT.[JournalofMedicinalChemistry,2002,vol.45,#7,p.1466-1476]

67-42-5    829-71-0   
{(2-{2-2-(bis-carboxymethyl-amino)-ethoxy-ethoxy}-ethyl)-2-(4-sulfamoyl-phenyl)-ethoxycarbonylmethyl-amino}-aceticacid 

[1]JournalofMedicinalChemistry,2002,vol.45,p.1466-1476

829-71-0    81-23-2   
(R)-4-((5S,8R,9S,10S,13R,14S,17R)-10,13-Dimethyl-3,7,12-trioxo-hexadecahydro-cyclopentaaphenanthren-17-yl)-pentanoicacid2-(4-sulfamoyl-phenyl)-ethylester 

[1]Bioorganicandmedicinalchemistryletters,2002,vol.12,p.1551-1557

Literature

Title: Molecular cloning, characterization, and inhibition studies of a β-carbonic anhydrase from Malassezia globosa, a potential antidandruff target.

Journal: Journal of medicinal chemistry 20120412

Title: Mutation of active site residues Asn67 to Ile, Gln92 to Val and Leu204 to Ser in human carbonic anhydrase II: influences on the catalytic activity and affinity for inhibitors.

Journal: Bioorganic & medicinal chemistry 20120401

Title: Cloning, characterization and sulfonamide inhibition studies of an α-carbonic anhydrase from the living fossil sponge Astrosclera willeyana.

Journal: Bioorganic & medicinal chemistry 20120215

Title: Inhibition studies of the β-carbonic anhydrases from the bacterial pathogen Salmonella enterica serovar Typhimurium with sulfonamides and sulfamates.

Journal: Bioorganic & medicinal chemistry 20110815

Title: A new β-carbonic anhydrase from Brucella suis, its cloning, characterization, and inhibition with sulfonamides and sulfamates, leading to impaired pathogen growth.

Journal: Bioorganic & medicinal chemistry 20110201

Title: Carbonic anhydrase inhibitors. Inhibition studies with anions and sulfonamides of a new cytosolic enzyme from the scleractinian coral Stylophora pistillata.

Journal: Bioorganic & medicinal chemistry letters 20110115

Title: Mutation of Phe91 to Asn in human carbonic anhydrase I unexpectedly enhanced both catalytic activity and affinity for sulfonamide inhibitors.

Journal: Bioorganic & medicinal chemistry 20100801

Title: 3D-QSAR study of benzene sulfonamide analogs as carbonic anhydrase II inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20100515

Title: Cloning, characterization, and inhibition studies of a beta-carbonic anhydrase from Brucella suis.

Journal: Journal of medicinal chemistry 20100311

Title: Carbonic anhydrase inhibitors. Characterization and inhibition studies of the most active beta-carbonic anhydrase from Mycobacterium tuberculosis, Rv3588c.

Journal: Bioorganic & medicinal chemistry letters 20091201

Title: Carbonic anhydrase inhibitors. Inhibition studies of a coral secretory isoform by sulfonamides.

Journal: Bioorganic & medicinal chemistry 20090715

Title: Carbonic anhydrase inhibitors. Inhibition and homology modeling studies of the fungal beta-carbonic anhydrase from Candida albicans with sulfonamides.

Journal: Bioorganic & medicinal chemistry 20090701

Title: Carbonic anhydrase inhibitors. Cloning, characterization, and inhibition studies of a new beta-carbonic anhydrase from Mycobacterium tuberculosis.

Journal: Journal of medicinal chemistry 20090514

Title: Molecular cloning, characterization, and inhibition studies of the Rv1284 beta-carbonic anhydrase from Mycobacterium tuberculosis with sulfonamides and a sulfamate.

Journal: Journal of medicinal chemistry 20090423

Title: Carbonic anhydrase inhibitors: inhibition of the beta-class enzyme from the yeast Saccharomyces cerevisiae with sulfonamides and sulfamates.

Journal: Bioorganic & medicinal chemistry 20090201

Title: Carbonic anhydrase inhibitors: cloning, characterization, and inhibition studies of the cytosolic isozyme III with sulfonamides.

Journal: Bioorganic & medicinal chemistry 20071201

Title: Carbonic anhydrase inhibitors: the beta-carbonic anhydrase from Helicobacter pylori is a new target for sulfonamide and sulfamate inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20070701

Title: Carbonic anhydrase inhibitors. DNA cloning, characterization, and inhibition studies of the human secretory isoform VI, a new target for sulfonamide and sulfamate inhibitors.

Journal: Journal of medicinal chemistry 20070125

Title: Carbonic anhydrase inhibitors: cloning and sulfonamide inhibition studies of a carboxyterminal truncated alpha-carbonic anhydrase from Helicobacter pylori.

Journal: Bioorganic & medicinal chemistry letters 20060415

Title: QSAR study on topically acting sulfonamides incorporating GABA moieties: a molecular connectivity approach.

Journal: Bioorganic & medicinal chemistry letters 20060401

Title: Carbonic anhydrase inhibitors: DNA cloning and inhibition studies of the alpha-carbonic anhydrase from Helicobacter pylori, a new target for developing sulfonamide and sulfamate gastric drugs.

Journal: Journal of medicinal chemistry 20060323

Title: Carbonic anhydrase inhibitors. The mitochondrial isozyme VB as a new target for sulfonamide and sulfamate inhibitors.

Journal: Journal of medicinal chemistry 20051201

Title: Carbonic anhydrase inhibitors: inhibition of the transmembrane isozyme XIV with sulfonamides.

Journal: Bioorganic & medicinal chemistry letters 20050901

Title: Carbonic anhydrase inhibitors. Inhibition of the transmembrane isozyme XII with sulfonamides-a new target for the design of antitumor and antiglaucoma drugs?

Journal: Bioorganic & medicinal chemistry letters 20050215

Title: Carbonic anhydrase inhibitors. Inhibition of the human cytosolic isozyme VII with aromatic and heterocyclic sulfonamides.

Journal: Bioorganic & medicinal chemistry letters 20050215

Title: Carbonic anhydrase inhibitors: inhibition of human cytosolic isozyme II and mitochondrial isozyme V with a series of benzene sulfonamide derivatives.

Journal: Bioorganic & medicinal chemistry letters 20041115

Title: Carbonic anhydrase inhibitors: the first QSAR study on inhibition of tumor-associated isoenzyme IX with aromatic and heterocyclic sulfonamides.

Journal: Bioorganic & medicinal chemistry letters 20040621

Title: Carbonic anhydrase inhibitors: inhibition of the tumor-associated isozyme IX with aromatic and heterocyclic sulfonamides.

Journal: Bioorganic & medicinal chemistry letters 20030324

Title: Carbonic anhydrase inhibitors. A general approach for the preparation of water-soluble sulfonamides incorporating polyamino-polycarboxylate tails and of their metal complexes possessing long-lasting, topical intraocular pressure-lowering properties.

Journal: Journal of medicinal chemistry 20020328

Title: Carbonic anhydrase inhibitors: synthesis of sulfonamides incorporating dtpa tails and of their zinc complexes with powerful topical antiglaucoma properties.

Journal: Bioorganic & medicinal chemistry letters 20010226

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Tags:829-71-0 Molecular Formula|829-71-0 MDL|829-71-0 SMILES|829-71-0 4-(2-hydroxyethyl)benzene-1-sulfonamide