Home Other Building Blocks 851536-75-9
851536-75-9,MFCD22124433
Catalog No.:AA00G77B

851536-75-9 | UMiroliMus

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1mg
≥95%
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$168.00   $117.00
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5mg
≥95%
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$662.00   $463.00
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10mg
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00G77B
Chemical Name:
UMiroliMus
CAS Number:
851536-75-9
Molecular Formula:
C55H87NO14
Molecular Weight:
986.2776
MDL Number:
MFCD22124433
SMILES:
CCOCCO[C@@H]1CC[C@H](C[C@H]1OC)C[C@H]([C@@H]1CC(=O)[C@H](C)/C=C(\C)/[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)/C=C/C=C/C=C(/[C@H](C[C@H]2O[C@](C(=O)C(=O)N3[C@H](C(=O)O1)CCCC3)(O)[C@H](C)CC2)OC)\C)C
Properties
Computed Properties
 
Complexity:
1840  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
15  
Defined Bond Stereocenter Count:
4  
Heavy Atom Count:
70  
Hydrogen Bond Acceptor Count:
14  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
11  
XLogP3:
6.8  

Literature

Title: Randomized comparison of the Nobori biolimus A9-eluting stent with the sirolimus-eluting stent in patients with stenosis in native coronary arteries.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20121101

Title: In vivo comparison of a polymer-free Biolimus A9-eluting stent with a biodegradable polymer-based Biolimus A9 eluting stent and a bare metal stent in balloon denuded and radiated hypercholesterolemic rabbit iliac arteries.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120901

Title: Effect of biolimus-eluting stents with biodegradable polymer vs bare-metal stents on cardiovascular events among patients with acute myocardial infarction: the COMFORTABLE AMI randomized trial.

Journal: JAMA 20120822

Title: New-generation drug-eluting stents for patients with myocardial infarction.

Journal: JAMA 20120822

Title: Clinical performance of a drug-eluting stent with a biodegradable polymer in an unselected patient population: the NOBORI 2 study.

Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120515

Title: Limus is not limus--a proposal to adjust terminology in the context of drug-eluting stents.

Journal: Journal of cardiovascular pharmacology 20120501

Title: Comparison of biolimus eluted from an erodible stent coating with bare metal stents in acute ST-elevation myocardial infarction (COMFORTABLE AMI trial): rationale and design.

Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120401

Title: Nobori stent shows less vascular inflammation and early recovery of endothelial function compared with Cypher stent.

Journal: JACC. Cardiovascular interventions 20120401

Title: Delamination of abluminal polymer of biolimus-eluting stent.

Journal: JACC. Cardiovascular interventions 20120301

Title: Polymer drug-eluting stents: is the future biodegradable?

Journal: Lancet (London, England) 20111203

Title: Long-term clinical outcomes of biodegradable polymer biolimus-eluting stents versus durable polymer sirolimus-eluting stents in patients with coronary artery disease (LEADERS): 4 year follow-up of a randomised non-inferiority trial.

Journal: Lancet (London, England) 20111203

Title: Comparison of pharmacokinetics of the limus-eluting stents in Japanese patients.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20111201

Title: The three year follow-up of the randomised 'all-comers' trial of a biodegradable polymer biolimus-eluting stent versus permanent polymer sirolimus-eluting stent (LEADERS).

Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20111101

Title: Long-term tissue coverage of a biodegradable polylactide polymer-coated biolimus-eluting stent: comparative sequential assessment with optical coherence tomography until complete resorption of the polymer.

Journal: American heart journal 20111101

Title: Implantation of the biodegradable polymer biolimus-eluting stent in patients with high SYNTAX score is associated with decreased cardiac mortality compared to a permanent polymer sirolimus-eluting stent: two year follow-up results from the 'all-comers' LEADERS trial.

Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110901

Title: [Biolimus eluting stent].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20110901

Title: 2-year clinical follow-up from the randomized comparison of biolimus-eluting stents with biodegradable polymer and sirolimus-eluting stents with durable polymer in routine clinical practice.

Journal: JACC. Cardiovascular interventions 20110801

Title: The pharmacokinetics of Biolimus A9 after elution from the BioMatrix II stent in patients with coronary artery disease: the Stealth PK Study.

Journal: European journal of clinical pharmacology 20110401

Title: Biolimus-eluting biodegradable polymer-coated stent versus bare metal stent in acute ST-elevation and non-ST elevation myocardial infarction: Justification for biodegradable polymer-coated stent in acute coronary syndrome (JANICE) registry.

Journal: Acute cardiac care 20110301

Title: The outcome of bifurcation lesion stenting using a biolimus-eluting stent with a bio-degradable polymer compared to a sirolimus-eluting stent with a durable polymer.

Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110301

Title: [Types and characteristic features of drug-eluting stents].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20110201

Title: Randomized, double-blind, placebo-controlled, single intravenous dose-escalation study to evaluate the safety, tolerability, and pharmacokinetics of the novel coronary smooth muscle cell proliferation inhibitor Biolimus A9 in healthy individuals.

Journal: Journal of clinical pharmacology 20110101

Title: The relationship between late lumen loss and restenosis among various drug-eluting stents: a systematic review and meta-regression analysis of randomized clinical trials.

Journal: Atherosclerosis 20110101

Title: Angioscopic assessment of arterial repair following biodegradable polymer-coated biolimus A9-eluting stent implantation. - Comparison with durable polymer-coated sirolimus-eluting stent-.

Journal: Circulation journal : official journal of the Japanese Circulation Society 20110101

Title: The AXXESS™ self-expanding biolimus A9™ eluting stent system for coronary bifurcation lesions.

Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20101201

Title: Long-term complication after LM bifurcation treatment.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100601

Title: Percutaneous UPLM revascularisation: the time has come.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100601

Title: The twelve-month outcomes of a biolimus eluting stent with a biodegradable polymer compared with a sirolimus eluting stent with a durable polymer.

Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100601

Title: The impact of body mass index on the one year outcomes of patients treated by percutaneous coronary intervention with Biolimus- and Sirolimus-eluting stents (from the LEADERS Trial).

Journal: The American journal of cardiology 20100215

Title: An optical coherence tomography study of a biodegradable vs. durable polymer-coated limus-eluting stent: a LEADERS trial sub-study.

Journal: European heart journal 20100101

Title: Anthropogenic factors and the risk of highly pathogenic avian influenza H5N1: prospects from a spatial-based model.

Journal: Veterinary research 20100101

Title: Clinical studies with sirolimus, zotarolimus, everolimus, and biolimus A9 drug-eluting stent systems.

Journal: Current pharmaceutical design 20100101

Title: Development and validation of a semi-automated assay for the highly sensitive quantification of Biolimus A9 in human whole blood using high-performance liquid chromatography-tandem mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20091101

Title: Scanning electron microscopic assessment of the biodegradable coating on expanded biolimus-eluting stents.

Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090901

Title: Impact of vessel size on angiographic and clinical outcomes of revascularization with biolimus-eluting stent with biodegradable polymer and sirolimus-eluting stent with durable polymer the LEADERS trial substudy.

Journal: JACC. Cardiovascular interventions 20090901

Title: Biolimus-eluting biodegradable polymer versus sirolimus-eluting permanent polymer stent performance in long lesions: results from the LEADERS multicentre trial substudy.

Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090801

Title: Reproducibility of quantitative optical coherence tomography for stent analysis.

Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090601

Title: Randomized comparison of the Nobori Biolimus A9-eluting coronary stent with the Taxus Liberté paclitaxel-eluting coronary stent in patients with stenosis in native coronary arteries: the NOBORI 1 trial--Phase 2.

Journal: Circulation. Cardiovascular interventions 20090601

Title: Long-term outcome after the V stenting technique in de novo bifurcation lesions using drug-eluting stents.

Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090601

Title: Correlation between quantitative angiographic and intravascular ultrasound parameters in patients treated with sirolimus analogous-eluting stents.

Journal: The international journal of cardiovascular imaging 20090401

Title: 9-month clinical, angiographic, and intravascular ultrasound results of a prospective evaluation of the Axxess self-expanding biolimus A9-eluting stent in coronary bifurcation lesions: the DIVERGE (Drug-Eluting Stent Intervention for Treating Side Branches Effectively) study.

Journal: Journal of the American College of Cardiology 20090324

Title: Analysis of left main coronary artery bifurcation lesions treated with biolimus-eluting DEVAX AXXESS plus nitinol self-expanding stent: intravascular ultrasound results of the AXXENT trial.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090101

Title: Treating the left main bifurcation lesion: the 'three stent solution'.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090101

Title: In vivo evaluation of a biolimus eluting nickel titanium self expanding stent with overlapping balloon expandable drug eluting and bare metal stents in a porcine coronary model.

Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090101

Title: The pharmacokinetics of Biolimus A9 after elution from the Nobori stent in patients with coronary artery disease: the NOBORI PK study.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20081201

Title: Interference of drug-eluting stents with endothelium-dependent coronary vasomotion: evidence for device-specific responses.

Journal: Circulation. Cardiovascular interventions 20081201

Title: Biolimus-eluting stent with biodegradable polymer versus sirolimus-eluting stent with durable polymer for coronary revascularisation (LEADERS): a randomised non-inferiority trial.

Journal: Lancet (London, England) 20080927

Title: Drug-eluting stents: is new necessarily better?

Journal: Lancet (London, England) 20080927

Title: One year results of a new in situ length-adjustable stent platform with a biodegradable biolimus A9 eluting polymer: results of the CUSTOM-II trial.

Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20080801

Title: Differential effects of drug-eluting stents on local endothelium-dependent coronary vasomotion.

Journal: Journal of the American College of Cardiology 20080603

Title: Novel drug eluting stent system for customised treatment of coronary lesions: CUSTOM I feasibility trial 24 month results.

Journal: EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20080501

Title: Future stent drug delivery systems.

Journal: Minerva cardioangiologica 20080201

Title: Results of percutaneous coronary intervention of the unprotected left main coronary artery in 143 patients and comparison of 30-day mortality to results of coronary artery bypass grafting.

Journal: The American journal of cardiology 20080101

Title: Drug-eluting stents - what should be improved?

Journal: Annals of medicine 20080101

Title: Analysis of bifurcation lesions treated with novel drug-eluting dedicated bifurcation stent system: intravascular ultrasound results of the AXXESS PLUS trial.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20071201

Title: Bifurcation stenting with a dedicated biolimus-eluting stent: X-ray visual enhancement of the final angiographic result with 'StentBoost Subtract'.

Journal: Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070801

Title: Six-month clinical and angiographic results of a dedicated drug-eluting stent for the treatment of coronary bifurcation narrowings.

Journal: The American journal of cardiology 20070615

Title: BioMatrix Biolimus A9-eluting coronary stent: a next-generation drug-eluting stent for coronary artery disease.

Journal: Expert review of medical devices 20061101

Title: Eberhard Grube, et al. BioMatrix Biolimus A9-eluting coronary stent: a next-generation drug-eluting stent for coronary artery disease. Expert Rev Med Devices. 2006 Nov;3(6):731-41.

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Tags:851536-75-9 Molecular Formula|851536-75-9 MDL|851536-75-9 SMILES|851536-75-9 UMiroliMus