Home Other Building Blocks 856866-72-3
856866-72-3,MFCD19442562
Catalog No.:AA00G3N8

856866-72-3 | Tedizolid

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
in stock  
$6.00   $4.00
- +
2mg
98%
in stock  
$8.00   $6.00
- +
5mg
98%
in stock  
$11.00   $8.00
- +
250mg
98%
in stock  
$16.00   $11.00
- +
1g
98%
in stock  
$42.00   $29.00
- +
5g
98%
in stock  
$154.00   $108.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00G3N8
Chemical Name:
Tedizolid
CAS Number:
856866-72-3
Molecular Formula:
C17H15FN6O3
Molecular Weight:
370.3378
MDL Number:
MFCD19442562
SMILES:
OC[C@@H]1OC(=O)N(C1)c1ccc(c(c1)F)c1ccc(nc1)c1nnn(n1)C
Properties
Computed Properties
 
Complexity:
543  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
27  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
4  
XLogP3:
1.4  

Literature

Title: Recent development of potent analogues of oxazolidinone antibacterial agents.

Journal: Bioorganic & medicinal chemistry 20130201

Title: Skin and soft tissue concentrations of tedizolid (formerly torezolid), a novel oxazolidinone, following a single oral dose in healthy volunteers.

Journal: International journal of antimicrobial agents 20120701

Title: The chemistry of peptidyltransferase center-targeted antibiotics: enzymatic resistance and approaches to countering resistance.

Journal: ACS chemical biology 20120120

Title: In vitro activity of tedizolid (TR-700) against linezolid-resistant staphylococci.

Journal: The Journal of antimicrobial chemotherapy 20120101

Title: Exploiting adaptive laboratory evolution of Streptomyces clavuligerus for antibiotic discovery and overproduction.

Journal: PloS one 20120101

Title: Discovery of torezolid as a novel 5-hydroxymethyl-oxazolidinone antibacterial agent.

Journal: European journal of medicinal chemistry 20110401

Title: Whole genome analysis of linezolid resistance in Streptococcus pneumoniae reveals resistance and compensatory mutations.

Journal: BMC genomics 20110101

Title: Cellular pharmacokinetics and intracellular activity of torezolid (TR-700): studies with human macrophage (THP-1) and endothelial (HUVEC) cell lines.

Journal: The Journal of antimicrobial chemotherapy 20091101

Title: In vitro activities of DA-7157 and DA-7218 against Mycobacterium tuberculosis and Nocardia brasiliensis.

Journal: Antimicrobial agents and chemotherapy 20060901

Title: Choi S, et al. Activity of Tedizolid Phosphate (TR-701) in Murine Models of Infection with Penicillin-resistant and Penicillin-sensitive Streptococcus pneumoniae. Antimicrob Agents Chemother. 2012 Jun 19.

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Tags:856866-72-3 Molecular Formula|856866-72-3 MDL|856866-72-3 SMILES|856866-72-3 Tedizolid