Title: Characterization of chicken cytochrome P450 1A4 and 1A5: inter-paralog comparisons of substrate preference and inhibitor selectivity.
Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20130501
Title: Different profiles of hepatic alkoxyresorufin O-dealkylase activities in small rodents.
Journal: Journal of applied toxicology : JAT 20121201
Title: Inhibition against mosquito cytochrome P450 enzymes by rhinacanthin-A, -B, and -C elicits synergism on cypermethrin cytotoxicity in Spodoptera frugiperda cells.
Journal: Journal of medical entomology 20120901
Title: Investigation by site-directed mutagenesis of the role of cytochrome P450 2B4 non-active-site residues in protein-ligand interactions based on crystal structures of the ligand-bound enzyme.
Journal: The FEBS journal 20120501
Title: Comparison of three fluorescent CYP3A substrates in two vertebrate models: pig and Atlantic salmon.
Journal: Animal : an international journal of animal bioscience 20120401
Title: Computational prediction of metabolism: sites, products, SAR, P450 enzyme dynamics, and mechanisms.
Journal: Journal of chemical information and modeling 20120326
Title: Characterization of enzyme activities of Cytochrome P450 enzymes, Flavin-dependent monooxygenases, N-acetyltransferases and UDP-glucuronyltransferases in human reconstructed epidermis and full-thickness skin models.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20110901
Title: Role of residue 87 in substrate selectivity and regioselectivity of drug-metabolizing cytochrome P450 CYP102A1 M11.
Journal: Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20110801
Title: Resorufin analogs preferentially bind cerebrovascular amyloid: potential use as imaging ligands for cerebral amyloid angiopathy.
Journal: Molecular neurodegeneration 20110101
Title: Computational approach to characterization of human liver drug-metabolizing enzymes.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20101009
Title: Functional differences in the cytochrome P450 1 family enzymes from zebrafish (Danio rerio) using heterologously expressed proteins.
Journal: Archives of biochemistry and biophysics 20101001
Title: Biotransformation of PCBs in Arctic seabirds: characterization of phase I and II pathways at transcriptional, translational and activity levels.
Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20100601
Title: Tertiary butyl alcohol in drinking water induces phase I and II liver enzymes with consequent effects on thyroid hormone homeostasis in the B6C3F1 female mouse.
Journal: Journal of applied toxicology : JAT 20100301
Title: 7-Benzyloxyresorufin-O-dealkylase activity as a marker for measuring cytochrome P450 CYP3A induction in mouse liver.
Journal: Analytical biochemistry 20100301
Title: 3D hepatic cultures simultaneously maintain primary hepatocyte and liver sinusoidal endothelial cell phenotypes.
Journal: PloS one 20100101
Title: DP7, a novel dihydropyridine multidrug resistance reverter, shows only weak inhibitory activity on human CYP3A enzyme(s).
Journal: European journal of pharmacology 20090701
Title: RNA interference-mediated knockdown of a cytochrome P450, CYP6BG1, from the diamondback moth, Plutella xylostella, reduces larval resistance to permethrin.
Journal: Insect biochemistry and molecular biology 20090101
Title: Effects of tributyltin (TBT) on in vitro hormonal and biotransformation responses in Atlantic salmon (Salmo salar).
Journal: Journal of toxicology and environmental health. Part A 20090101
Title: Defining the in Vivo Role for cytochrome b5 in cytochrome P450 function through the conditional hepatic deletion of microsomal cytochrome b5.
Journal: The Journal of biological chemistry 20081114
Title: Catalytic function of avian cytochrome P450 1A4 and 1A5 (CYP1A4 and CYP1A5) enzymes heterologously expressed using in vitro yeast system.
Journal: Marine environmental research 20080701
Title: Characterization of inhibitors and substrates of Anopheles gambiae CYP6Z2.
Journal: Insect molecular biology 20080401
Title: Purification of CYP2B-like protein from feral leaping mullet (Liza saliens) liver microsomes and its biocatalytic, molecular, and immunological characterization.
Journal: Journal of biochemical and molecular toxicology 20080101
Title: Non invasive in vivo investigation of hepatobiliary structure and function in STII medaka (Oryzias latipes): methodology and applications.
Journal: Comparative hepatology 20080101
Title: An in silico transwell device for the study of drug transport and drug-drug interactions.
Journal: Pharmaceutical research 20071201
Title: An alternatively spliced cytochrome P4501A1 in human brain fails to bioactivate polycyclic aromatic hydrocarbons to DNA-reactive metabolites.
Journal: Journal of neurochemistry 20070801
Title: Expression and characterization of cytochrome P450 2X1 in channel catfish (Ictalurus punctatus).
Journal: Biochimica et biophysica acta 20070701
Title: Modulation of xenobiotic biotransformation system and hormonal responses in Atlantic salmon (Salmo salar) after exposure to tributyltin (TBT).
Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20070401
Title: Re-engineering cytochrome P450 2B11dH for enhanced metabolism of several substrates including the anti-cancer prodrugs cyclophosphamide and ifosfamide.
Journal: Archives of biochemistry and biophysics 20070215
Title: OPC-67683, a nitro-dihydro-imidazooxazole derivative with promising action against tuberculosis in vitro and in mice.
Journal: PLoS medicine 20061101
Title: Furocoumarins from grapefruit juice and their effect on human CYP 3A4 and CYP 1B1 isoenzymes.
Journal: Bioorganic & medicinal chemistry 20060415
Title: QSAR modeling of in vitro inhibition of cytochrome P450 3A4.
Journal: Journal of chemical information and modeling 20060101
Title: Functional characterization of medaka CYP3A38 and CYP3A40: kinetics and catalysis by expression in a recombinant baculovirus system.
Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20050801
Title: Directed evolution of mammalian cytochrome P450 2B1: mutations outside of the active site enhance the metabolism of several substrates, including the anticancer prodrugs cyclophosphamide and ifosfamide.
Journal: The Journal of biological chemistry 20050520
Title: Effects of light and dark beer on hepatic cytochrome P-450 expression in male rats receiving alcoholic beverages as part of total enteral nutrition.
Journal: Alcoholism, clinical and experimental research 20050501
Title: Functional role of residues in the helix B' region of cytochrome P450 2B1.
Journal: Archives of biochemistry and biophysics 20050301
Title: Isolation and characterization of metabolically competent pulmonary epithelial cells from pig lung tissue.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20050101
Title: Pretreatment with 1,8-cineole potentiates thioacetamide-induced hepatotoxicity and immunosuppression.
Journal: Archives of pharmacal research 20040701
Title: Mutagenesis and molecular dynamics suggest structural and functional roles for residues in the N-terminal portion of the cytochrome P450 2B1 I helix.
Journal: Archives of biochemistry and biophysics 20040315
Title: Utility of microtiter plate assays for human cytochrome P450 inhibition studies in drug discovery: application of simple method for detecting quasi-irreversible and irreversible inhibitors.
Journal: Drug metabolism and pharmacokinetics 20040201
Title: Effects of propranolol on xenobiotic enzyme activities in rat type II pneumocytes and alveolar macrophages in vivo.
Journal: Methods and findings in experimental and clinical pharmacology 20031201
Title: Activities of drug metabolizing enzymes in bovine colon epithelial cell cultures.
Journal: Archives of toxicology 20031101
Title: Differential inhibition of human cytochrome P450 enzymes by epsilon-viniferin, the dimer of resveratrol: comparison with resveratrol and polyphenols from alcoholized beverages.
Journal: Life sciences 20030718
Title: In vitro activation of 7-benzyloxyresorufin O-debenzylation and nifedipine oxidation in human liver microsomes.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20030701
Title: Essential requirements for substrate binding affinity and selectivity toward human CYP2 family enzymes.
Journal: Archives of biochemistry and biophysics 20030101
Title: Cytochrome P450 fluorometric substrates: identification of isoform-selective probes for rat CYP2D2 and human CYP3A4.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20020701
Title: Substrate specificity for rat cytochrome P450 (CYP) isoforms: screening with cDNA-expressed systems of the rat.
Journal: Biochemical pharmacology 20020301
Title: Combined three-dimensional quantitative structure-activity relationship analysis of cytochrome P450 2B6 substrates and protein homology modeling.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20020101
Title: Ovariectomy modulates the response of some cytochrome P450 isozymes to lindane in the rat.
Journal: Toxicology letters 20011015
Title: Xenobiotic-metabolizing enzyme activities in primary cultures of rat type II pneumocytes and alveolar macrophages.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20011001
Title: Catalytic and immunochemical properties of hepatic cytochrome P450 1A in three avian species treated with beta-naphthoflavone or isosafrole.
Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20010901
Title: Spatially focused deposition of capillary electrophoresis effluent onto surface-enhanced Raman-active substrates for off-column spectroscopy.
Journal: Electrophoresis 20010701
Title: Substrate inhibition kinetics for cytochrome P450-catalyzed reactions.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20010401
Title: P450 enzyme expression patterns in the NCI human tumor cell line panel.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20010301
Title: Specificity of substrate and inhibitor probes for cytochrome P450s: evaluation of in vitro metabolism using cDNA-expressed human P450s and human liver microsomes.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 19960701
