Title: 1-substituted (Dibenzo[b,d]thiophen-4-yl)-2-morpholino-4H-chromen-4-ones endowed with dual DNA-PK/PI3-K inhibitory activity.
Journal: Journal of medicinal chemistry 20130822
Title: Identification of potent Yes1 kinase inhibitors using a library screening approach.
Journal: Bioorganic & medicinal chemistry letters 20130801
Title: Modulation of DNA repair by pharmacological inhibitors of the PIKK protein kinase family.
Journal: Bioorganic & medicinal chemistry letters 20120901
Title: Chemosensitization of cancer cells by KU-0060648, a dual inhibitor of DNA-PK and PI-3K.
Journal: Molecular cancer therapeutics 20120801
Title: DNA-dependent protein kinase (DNA-PK) inhibitors: structure-activity relationships for O-alkoxyphenylchromen-4-one probes of the ATP-binding domain.
Journal: Bioorganic & medicinal chemistry letters 20110201
Title: DNA-dependent protein kinase (DNA-PK) inhibitors. Synthesis and biological activity of quinolin-4-one and pyridopyrimidin-4-one surrogates for the chromen-4-one chemotype.
Journal: Journal of medicinal chemistry 20101223
Title: Mapping the ATP-binding domain of DNA-dependent protein kinase (DNA-PK) with coumarin- and isocoumarin-derived inhibitors.
Journal: Bioorganic & medicinal chemistry letters 20100615
Title: The DNA-dependent protein kinase.
Journal: Genes & development 19990415
Title: Radiosensitization of human tumor cells by the phosphatidylinositol3-kinase inhibitors wortmannin and LY294002 correlates with inhibition of DNA-dependent protein kinase and prolonged G2-M delay.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 19970701
Title: Differential implications of the oncogene-tumor suppressor gene complex in the geneses of 19 human neoplasias. Evidence in support of the steroid carcinogenesis hypothesis.
Journal: Anticancer research 19970101
