88235-25-0,MFCD00057884
Catalog No.:AA004B2R

88235-25-0 | 6-((7-Nitrobenzo[c][1,2,5]oxadiazol-4-yl)amino)hexanoic acid

Pack Size
Purity
Availability
Price(USD)
Quantity
  
200mg
≥96%
in stock  
$270.00   $189.00
- +
1g
≥96%
in stock  
$878.00   $614.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA004B2R
Chemical Name:
6-((7-Nitrobenzo[c][1,2,5]oxadiazol-4-yl)amino)hexanoic acid
CAS Number:
88235-25-0
Molecular Formula:
C12H14N4O5
Molecular Weight:
294.2634
MDL Number:
MFCD00057884
SMILES:
OC(=O)CCCCCNc1ccc(c2c1non2)[N+](=O)[O-]
Properties
Properties
 
BP:
559.4°C at 760 mmHg  
Form:
Solid  
MP:
152 - 154°C  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
375  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
21  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0  
Rotatable Bond Count:
7  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
1.6  

Downstream Synthesis Route

[1]Greco,Graziella;D'Antona,Nicola;Gambera,Giovanni;Nicolosi,Giovanni[Synlett,2014,vol.25,#15,p.2111-2114]

[2]Woodland,JohnG.;Hunter,Roger;Smith,PeterJ.;Egan,TimothyJ.[OrganicandBiomolecularChemistry,2017,vol.15,#3,p.589-597]

[3]Storz,MichaelP.;Allegretta,Giuseppe;Kirsch,Benjamin;Empting,Martin;Hartmann,RolfW.[OrganicandBiomolecularChemistry,2014,vol.12,#32,p.6094-6104]

[4]Jida,Mouhamad;Sanchez,CeciliaP.;Urgin,Karène;Ehrhardt,Katharina;Mounien,Saravanan;Geyer,Aurelia;Elhabiri,Mourad;Lanzer,Michael;Davioud-Charvet,Elisabeth[ACSInfectiousDiseases,2017,vol.3,#2,p.119-131]

[5]Novotný,Jakub;Pospěchová,Kateřina;Hrabálek,Alexandr;Čáp,Robert;Vávrová,Kateřina[BioorganicandMedicinalChemistryLetters,2009,vol.19,#24,p.6975-6977]

[6]Huang,Chusen;Yin,Qin;Meng,Jiangjiang;Zhu,Weiping;Yang,Yi;Qian,Xuhong;Xu,Yufang[Chemistry-AEuropeanJournal,2013,vol.19,#24,p.7739-7747]

[7]Ludolph,Bjoern;Waldmann,Herbert[Chemistry-AEuropeanJournal,2003,vol.9,#15,p.3683-3691]

[8]Wenskowsky,Lea;Schreuder,Herman;Derdau,Volker;Matter,Hans;Volkmar,Julia;Nazaré,Marc;Opatz,Till;Petry,Stefan[AngewandteChemie-InternationalEdition,2018,vol.57,#4,p.1044-1048][Angew.Chem.,2018,vol.130,p.1056-1060,5]

[9]Kopečná,Monika;Kováčik,Andrej;Kučera,Ondřej;Macháček,Miloslav;Sochorová,Michaela;Audrlická,Pavla;Vávrová,Kateřina[MolecularPharmaceutics,2019,vol.16,#2,p.886-897]

[10]Haldar,Saikat;Kumar,Santosh;Kolet,SwatiP.;Patil,HarshalS.;Kumar,Dhiraj;Kundu,GopalC.;Thulasiram,HirekodathakalluV.[JournalofOrganicChemistry,2013,vol.78,#20,p.10192-10202]

[11]CurrentPatentAssignee:ZHEJIANGUNIVERSITY-CN105295896,2017,BLocationinpatent:Paragraph0053;0054

73724-43-3    111061-56-4    88235-25-0    438620-68-9   
NBDAca-Ser(Trt)-Cys(SS-t-Bu)-Lys(Aloc)-Cys(farnesyl) 

[1]JournaloftheAmericanChemicalSociety,2002,vol.124,p.5954-5955

1196-92-5    88235-25-0   
C20H23N5O6 

[1]CurrentPatentAssignee:ZHEJIANGUNIVERSITY-CN105295896,2017,BLocationinpatent:Paragraph0046;0047

[1]Arenz,Christoph;Basu,Shibom;Bechara,Cherine;Bossis,Guillaume;Cong,Xiaojing;DelNero,Elise;Drapeau,Marion;Fontanel,Simon;Gabellier,Ludovic;Golebiowski,Jérôme;Granier,Sebastien;Healey,RobertD.;Hornemann,Thorsten;Jeannot,Sylvain;Karsai,Gergely;Leyrat,Cedric;Maurel,Damien;Saied,EssaM.;Saint-Paul,Julie[AngewandteChemie-InternationalEdition,2022,vol.61,#2][Angew.Chem.,2022,vol.134,#2,p.11111-11118]

Literature

Title: Solvent-dependent changes in molecular reorientation dynamics: the role of solvent-solvent interactions.

Journal: The journal of physical chemistry. A 20100415

Title: Interaction of GB virus C/hepatitis G virus synthetic peptides with lipid langmuir monolayers and large unilamellar vesicles.

Journal: The journal of physical chemistry. B 20090108

Title: Bile salt-phospholipid aggregation at submicellar concentrations.

Journal: Colloids and surfaces. B, Biointerfaces 20080401

Title: Investigation of nonspecific effects of different dyes in the screening of labeled carbohydrates against immobilized proteins.

Journal: The Journal of organic chemistry 20051125

Title: Chemical synthesis of triple-labelled three-helix bundle binding proteins for specific fluorescent detection of unlabelled protein.

Journal: Chembiochem : a European journal of chemical biology 20050601

Title: Role of prothrombin fragment 1 in the pathway of regulatory exosite I formation during conversion of human prothrombin to thrombin.

Journal: The Journal of biological chemistry 20031107

Title: Dual labeling of a binding protein allows for specific fluorescence detection of native protein.

Journal: Analytical biochemistry 20010801

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Tags:88235-25-0 Molecular Formula|88235-25-0 MDL|88235-25-0 SMILES|88235-25-0 6-((7-Nitrobenzo[c][1,2,5]oxadiazol-4-yl)amino)hexanoic acid
Catalog No.: AA004B2R
88235-25-0,MFCD00057884
88235-25-0 | 6-((7-Nitrobenzo[c][1,2,5]oxadiazol-4-yl)amino)hexanoic acid
Pack Size: 200mg
Purity: ≥96%
in stock
$270.00 $189.00
Pack Size: 1g
Purity: ≥96%
in stock
$878.00 $614.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA004B2R
Chemical Name: 6-((7-Nitrobenzo[c][1,2,5]oxadiazol-4-yl)amino)hexanoic acid
CAS Number: 88235-25-0
Molecular Formula: C12H14N4O5
Molecular Weight: 294.2634
MDL Number: MFCD00057884
SMILES: OC(=O)CCCCCNc1ccc(c2c1non2)[N+](=O)[O-]
Properties
BP: 559.4°C at 760 mmHg  
Form: Solid  
MP: 152 - 154°C  
Storage: Keep in dry area;2-8℃;  
Complexity: 375  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 21  
Hydrogen Bond Acceptor Count: 8  
Hydrogen Bond Donor Count: 2  
Isotope Atom Count: 0  
Rotatable Bond Count: 7  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 1.6  
Downstream Synthesis Route
10199-89-0    60-32-2    88235-25-0 

[1]Greco,Graziella;D'Antona,Nicola;Gambera,Giovanni;Nicolosi,Giovanni[Synlett,2014,vol.25,#15,p.2111-2114]

[2]Woodland,JohnG.;Hunter,Roger;Smith,PeterJ.;Egan,TimothyJ.[OrganicandBiomolecularChemistry,2017,vol.15,#3,p.589-597]

[3]Storz,MichaelP.;Allegretta,Giuseppe;Kirsch,Benjamin;Empting,Martin;Hartmann,RolfW.[OrganicandBiomolecularChemistry,2014,vol.12,#32,p.6094-6104]

[4]Jida,Mouhamad;Sanchez,CeciliaP.;Urgin,Karène;Ehrhardt,Katharina;Mounien,Saravanan;Geyer,Aurelia;Elhabiri,Mourad;Lanzer,Michael;Davioud-Charvet,Elisabeth[ACSInfectiousDiseases,2017,vol.3,#2,p.119-131]

[5]Novotný,Jakub;Pospěchová,Kateřina;Hrabálek,Alexandr;Čáp,Robert;Vávrová,Kateřina[BioorganicandMedicinalChemistryLetters,2009,vol.19,#24,p.6975-6977]

[6]Huang,Chusen;Yin,Qin;Meng,Jiangjiang;Zhu,Weiping;Yang,Yi;Qian,Xuhong;Xu,Yufang[Chemistry-AEuropeanJournal,2013,vol.19,#24,p.7739-7747]

[7]Ludolph,Bjoern;Waldmann,Herbert[Chemistry-AEuropeanJournal,2003,vol.9,#15,p.3683-3691]

[8]Wenskowsky,Lea;Schreuder,Herman;Derdau,Volker;Matter,Hans;Volkmar,Julia;Nazaré,Marc;Opatz,Till;Petry,Stefan[AngewandteChemie-InternationalEdition,2018,vol.57,#4,p.1044-1048][Angew.Chem.,2018,vol.130,p.1056-1060,5]

[9]Kopečná,Monika;Kováčik,Andrej;Kučera,Ondřej;Macháček,Miloslav;Sochorová,Michaela;Audrlická,Pavla;Vávrová,Kateřina[MolecularPharmaceutics,2019,vol.16,#2,p.886-897]

[10]Haldar,Saikat;Kumar,Santosh;Kolet,SwatiP.;Patil,HarshalS.;Kumar,Dhiraj;Kundu,GopalC.;Thulasiram,HirekodathakalluV.[JournalofOrganicChemistry,2013,vol.78,#20,p.10192-10202]

[11]CurrentPatentAssignee:ZHEJIANGUNIVERSITY-CN105295896,2017,BLocationinpatent:Paragraph0053;0054

73724-43-3    111061-56-4    88235-25-0    438620-68-9   
NBDAca-Ser(Trt)-Cys(SS-t-Bu)-Lys(Aloc)-Cys(farnesyl) 

[1]JournaloftheAmericanChemicalSociety,2002,vol.124,p.5954-5955

1196-92-5    88235-25-0   
C20H23N5O6 

[1]CurrentPatentAssignee:ZHEJIANGUNIVERSITY-CN105295896,2017,BLocationinpatent:Paragraph0046;0047

5514-98-7    88235-25-0 

[1]Arenz,Christoph;Basu,Shibom;Bechara,Cherine;Bossis,Guillaume;Cong,Xiaojing;DelNero,Elise;Drapeau,Marion;Fontanel,Simon;Gabellier,Ludovic;Golebiowski,Jérôme;Granier,Sebastien;Healey,RobertD.;Hornemann,Thorsten;Jeannot,Sylvain;Karsai,Gergely;Leyrat,Cedric;Maurel,Damien;Saied,EssaM.;Saint-Paul,Julie[AngewandteChemie-InternationalEdition,2022,vol.61,#2][Angew.Chem.,2022,vol.134,#2,p.11111-11118]

Literature fold

Title: Solvent-dependent changes in molecular reorientation dynamics: the role of solvent-solvent interactions.

Journal: The journal of physical chemistry. A20100415

Title: Interaction of GB virus C/hepatitis G virus synthetic peptides with lipid langmuir monolayers and large unilamellar vesicles.

Journal: The journal of physical chemistry. B20090108

Title: Bile salt-phospholipid aggregation at submicellar concentrations.

Journal: Colloids and surfaces. B, Biointerfaces20080401

Title: Investigation of nonspecific effects of different dyes in the screening of labeled carbohydrates against immobilized proteins.

Journal: The Journal of organic chemistry20051125

Title: Chemical synthesis of triple-labelled three-helix bundle binding proteins for specific fluorescent detection of unlabelled protein.

Journal: Chembiochem : a European journal of chemical biology20050601

Title: Role of prothrombin fragment 1 in the pathway of regulatory exosite I formation during conversion of human prothrombin to thrombin.

Journal: The Journal of biological chemistry20031107

Title: Dual labeling of a binding protein allows for specific fluorescence detection of native protein.

Journal: Analytical biochemistry20010801

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