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9001-73-4,MFCD00131791
Catalog No.:AA003920

9001-73-4 | Papain

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100mg
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA003920
Chemical Name:
Papain
CAS Number:
9001-73-4
Molecular Formula:
C9H14N4O3
Molecular Weight:
226.2325
MDL Number:
MFCD00131791
SMILES:
C1=C(NC=N1)CC(C(=O)O)NC(=O)CCN
NSC Number:
524045
Properties
Computed Properties
 
Complexity:
259  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
16  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
6  
Undefined Atom Stereocenter Count:
1  
XLogP3:
-4  

Literature

Title: Use of viscera extract from hybrid catfish (Clarias macrocephalus × Clarias gariepinus) for the production of protein hydrolysate from toothed ponyfish (Gazza minuta) muscle.

Journal: Food chemistry 20130115

Title: Treatment of Phaeodactylum tricornutum cells with papain facilitates lipid extraction.

Journal: Journal of biotechnology 20121130

Title: Studies on the chemical modification of goat liver cystatin and the effect on its anti-papain inhibitory activity.

Journal: Journal of fluorescence 20121101

Title: A novel in vivo rabbit model of abdominal aortic aneurysm induced by periarterial incubation of papain.

Journal: Journal of vascular and interventional radiology : JVIR 20121101

Title: Enhancement of protease-induced IL-6 release in monocytic U-937 cells by phorbol-12-myristate-13-acetate.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20121001

Title: Fluorescence spectroscopic analysis of the interaction of papain with ionic liquids.

Journal: Applied biochemistry and biotechnology 20121001

Title: Purification of chicken breast protein hydrolysate and analysis of its antioxidant activity.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20121001

Title: Development and validation of a rapid capillary zone electrophoresis method for determining charge variants of mAb.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20121001

Title: Cystatin B homolog from rock bream Oplegnathus fasciatus: genomic characterization, transcriptional profiling and protease-inhibitory activity of recombinant protein.

Journal: Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20120901

Title: Chondroprotective and anti-inflammatory effects of sesamin.

Journal: Phytochemistry 20120801

Title: Isolation and characterization of bioactive pro-peptides with in vitro renin inhibitory activities from the macroalga Palmaria palmata.

Journal: Journal of agricultural and food chemistry 20120801

Title: Purification and identification of antioxidant peptides from egg white protein hydrolysate.

Journal: Amino acids 20120701

Title: Cryptostatin, a chagasin-family cysteine protease inhibitor of Cryptosporidium parvum.

Journal: Parasitology 20120701

Title: Papain-specific activating esters in aqueous dipeptide synthesis.

Journal: Chembiochem : a European journal of chemical biology 20120618

Title: Optimisation of hydrolysis of purple sea urchin (Strongylocentrotus nudus) gonad by response surface methodology and evaluation of in vitro antioxidant activity of the hydrolysate.

Journal: Journal of the science of food and agriculture 20120601

Title: Influence of incubation conditions on hydrolysis efficiency and iodine enrichment in baker's yeast.

Journal: Biological trace element research 20120601

Title: Purification of papain using reactive green 5 attached supermacroporous monolithic cryogel.

Journal: Applied biochemistry and biotechnology 20120601

Title: Reactivity of nitroxyl-derived sulfinamides.

Journal: Biochemistry 20120522

Title: Optimization of a microwave-coupled enzymatic digestion process to prepare peanut peptides.

Journal: Molecules (Basel, Switzerland) 20120511

Title: C1A cysteine-proteases and their inhibitors in plants.

Journal: Physiologia plantarum 20120501

Title: Naive T cells sense the cysteine protease allergen papain through protease-activated receptor 2 and propel TH2 immunity.

Journal: The Journal of allergy and clinical immunology 20120501

Title: Aggregation and inactivation of pancreatic cystatin by riboflavin-derived singlet oxygen and flavin triplet state: polyphenols as preventive agents.

Journal: Journal of biochemical and molecular toxicology 20120501

Title: A dityrosine-based substrate for a protease assay: application for the selective assessment of papain and chymopapain activity.

Journal: Analytica chimica acta 20120420

Title: Subclassification and biochemical analysis of plant papain-like cysteine proteases displays subfamily-specific characteristics.

Journal: Plant physiology 20120401

Title: 3-aminopiperidine-based peptide analogues as the first selective noncovalent inhibitors of the bacterial cysteine protease IdeS.

Journal: Journal of medicinal chemistry 20120322

Title: A potent, versatile disulfide-reducing agent from aspartic acid.

Journal: Journal of the American Chemical Society 20120307

Title: Enzyme catalytic promiscuity: The papain-catalyzed Knoevenagel reaction.

Journal: Biochimie 20120301

Title: Fish protein hydrolysates affect cholesterol metabolism in rats fed non-cholesterol and high-cholesterol diets.

Journal: Journal of medicinal food 20120301

Title: Characterization of the isomerization products of aspartate residues at two different sites in a monoclonal antibody.

Journal: Pharmaceutical research 20120101

Title: Assessment of the angiotensin-I-converting enzyme (ACE-I) inhibitory and antioxidant activities of hydrolysates of bovine brisket sarcoplasmic proteins produced by papain and characterisation of associated bioactive peptidic fractions.

Journal: Meat science 20120101

Title: Rodent retinal ganglion cell cultures.

Journal: Methods in molecular biology (Clifton, N.J.) 20120101

Title: Clinical evaluation of caries removal in primary teeth using conventional, chemomechanical and laser technique: an in vivo study.

Journal: The journal of contemporary dental practice 20120101

Title: Production of defatted palm kernel cake protein hydrolysate as a valuable source of natural antioxidants.

Journal: International journal of molecular sciences 20120101

Title: Isolation and gene expression analysis of a papain-type cysteine protease in thermogenic skunk cabbage (Symplocarpus renifolius).

Journal: Bioscience, biotechnology, and biochemistry 20120101

Title: The reaction of H(2)S with oxidized thiols: generation of persulfides and implications to H(2)S biology.

Journal: Archives of biochemistry and biophysics 20111215

Title: Identification of interactions involved in the generation of nucleophilic reactivity and of catalytic competence in the catalytic site Cys/His ion pair of papain.

Journal: Biochemistry 20111213

Title: Free radical scavenging and angiotensin-I converting enzyme inhibitory peptides from Pacific cod (Gadus macrocephalus) skin gelatin.

Journal: International journal of biological macromolecules 20111201

Title: Interactions of nanobubbles with bovine serum albumin and papain films on gold surfaces.

Journal: Biointerphases 20111201

Title: Efficacy of chitooligosaccharides for the management of diabetes in alloxan induced mice: a correlative study with antihyperlipidemic and antioxidative activity.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20111120

Title: Development of a new experimental model of saccular aneurysm by intra-arterial incubation of papain in rabbits.

Journal: Neuroradiology 20111101

Title: 3A4, a new potential target for B and myeloid lineage leukemias.

Journal: Journal of drug targeting 20111101

Title: Immobilization and stabilization of papain on poly(hydroxyethyl methacrylate-ethylenglycol dimethacrylate) beads grafted with epoxy functional polymer chains via surface-initiated-atom transfer radical polymerization (SI-ATRP).

Journal: Bioresource technology 20111101

Title: Metal ion mediated self-assembly directed formation of protein arrays.

Journal: Biomacromolecules 20111010

Title: An IL-9 fate reporter demonstrates the induction of an innate IL-9 response in lung inflammation.

Journal: Nature immunology 20111009

Title: Respiratory mechanics do not always mirror pulmonary histological changes in emphysema.

Journal: Clinics (Sao Paulo, Brazil) 20111001

Title: Papain-catalyzed peptide bond formation: enzyme-specific activation with guanidinophenyl esters.

Journal: Chembiochem : a European journal of chemical biology 20110919

Title: Chemically engineered papain as artificial formate dehydrogenase for NAD(P)H regeneration.

Journal: Organic & biomolecular chemistry 20110821

Title: Stain removal efficacy of a novel dentifrice containing papain and Bromelain extracts--an in vitro study.

Journal: International journal of dental hygiene 20110801

Title: Crystal structure of tarocystatin-papain complex: implications for the inhibition property of group-2 phytocystatins.

Journal: Planta 20110801

Title: Keratin film made of human hair as a nail plate model for studying drug permeation.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20110801

Title: Antioxidant and antiproliferative activities of loach ( Misgurnus anguillicaudatus ) peptides prepared by papain digestion.

Journal: Journal of agricultural and food chemistry 20110727

Title: Isolation and characterization of three novel peptides from casein hydrolysates that stimulate the growth of mixed cultures of Streptococcus thermophilus and Lactobacillus delbrueckii subsp. bulgaricus.

Journal: Journal of agricultural and food chemistry 20110713

Title: Ribosome display selection of a murine IgG₁ Fab binding affibody molecule allowing species selective recovery of monoclonal antibodies.

Journal: Molecular biotechnology 20110701

Title: The nonstructural protein 1 papain-like cysteine protease was necessary for porcine reproductive and respiratory syndrome virus nonstructural protein 1 to inhibit interferon-β induction.

Journal: DNA and cell biology 20110601

Title: Inflammation-associated autophagy-related programmed necrotic death of human neutrophils characterized by organelle fusion events.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20110601

Title: A novel transglutaminase substrate from Streptomyces mobaraensis inhibiting papain-like cysteine proteases.

Journal: Journal of microbiology and biotechnology 20110601

Title: Marasmius oreades agglutinin (MOA) is a chimerolectin with proteolytic activity.

Journal: Biochemical and biophysical research communications 20110513

Title: The mechanism of papain inhibition by peptidyl aldehydes.

Journal: Proteins 20110301

Title: Molecular cloning and biochemical characterization of a novel cystatin from Hevea rubber latex.

Journal: Plant physiology and biochemistry : PPB 20110301

Title: Metastability of papain and the molecular mechanism for its sequential acid-denaturation.

Journal: The protein journal 20110301

Title: Morphology and microtensile bond strength of adhesive systems to in situ-formed caries-affected dentin after the use of a papain-based chemomechanical gel method.

Journal: American journal of dentistry 20110201

Title: Backbone degradable multiblock N-(2-hydroxypropyl)methacrylamide copolymer conjugates via reversible addition-fragmentation chain transfer polymerization and thiol-ene coupling reaction.

Journal: Biomacromolecules 20110110

Title: Surface Plasmon Resonance Imaging (SPRI) sensor for cystatin determination based on immobilized papain.

Journal: Protein and peptide letters 20110101

Title: PLP2 of mouse hepatitis virus A59 (MHV-A59) targets TBK1 to negatively regulate cellular type I interferon signaling pathway.

Journal: PloS one 20110101

Title: Sodium tetrathionate effect on papain purification from different Carica papaya latex crude extracts.

Journal: Preparative biochemistry & biotechnology 20110101

Title: Papain-like proteases of Staphylococcus aureus.

Journal: Advances in experimental medicine and biology 20110101

Title: Structural analysis of papain-like NlpC/P60 superfamily enzymes with a circularly permuted topology reveals potential lipid binding sites.

Journal: PloS one 20110101

Title: Development of enteric submicron particle formulation of papain for oral delivery.

Journal: International journal of nanomedicine 20110101

Title: Kinetically controlled enzymatic synthesis of dipeptide precursor of L-alanyl-L-glutamine.

Journal: Biotechnology and applied biochemistry 20110101

Title: An evaluation of different caries removal techniques in primary teeth: a comparitive clinical study.

Journal: The Journal of clinical pediatric dentistry 20110101

Title: Removal of mercury (II) from aqueous solution using papain immobilized on alginate bead: optimization of immobilization condition and modeling of removal study.

Journal: Bioresource technology 20101201

Title: Reduction of benzaldehyde catalyzed by papain-based semisynthetic enzymes.

Journal: Applied biochemistry and biotechnology 20101101

Title: High level production of bioactive di- and tri-tyrosine peptides by protease-catalyzed reactions.

Journal: Journal of biotechnology 20101101

Title: The effect of various wound dressings on the activity of debriding enzymes.

Journal: Advances in skin & wound care 20101001

Title: A distinct subfamily of papain-like cystein proteinases regulated by senescence and stresses in Glycine max.

Journal: Journal of plant physiology 20100901

Title: Plant cysteine proteases that evoke itch activate protease-activated receptors.

Journal: The British journal of dermatology 20100901

Title: Identification and characterization of a Cystatin gene from Chinese mitten crab Eriocheir sinensis.

Journal: Fish & shellfish immunology 20100901

Title: Structural and mechanistic insights into a novel non-competitive Kunitz trypsin inhibitor from Adenanthera pavonina L. seeds with double activity toward serine- and cysteine-proteinases.

Journal: Journal of molecular graphics & modelling 20100901

Title: Optimization of hydrolysis conditions for the production of antioxidant peptides from fish gelatin using response surface methodology.

Journal: Journal of food science 20100801

Title: Isolation, structure, and functional elucidation of a modified pentapeptide, cysteine protease inhibitor (CPI-2081) from Streptomyces species 2081 that exhibit inhibitory effect on cancer cell migration.

Journal: Journal of medicinal chemistry 20100722

Title: The effects of different maceration techniques on nuclear DNA amplification using human bone.

Journal: Journal of forensic sciences 20100701

Title: The T helper type 2 response to cysteine proteases requires dendritic cell-basophil cooperation via ROS-mediated signaling.

Journal: Nature immunology 20100701

Title: Mesoporous organosilicas with ultra-large pores: mesophase transformation and bioadsorption properties.

Journal: Journal of colloid and interface science 20100601

Title: Improving thermostability of papain through structure-based protein engineering.

Journal: Protein engineering, design & selection : PEDS 20100601

Title: Protease allergens induce the expression of IL-25 via Erk and p38 MAPK pathway.

Journal: Journal of Korean medical science 20100601

Title: Reaction mechanisms of allicin and allyl-mixed disulfides with proteins and small thiol molecules.

Journal: European journal of medicinal chemistry 20100501

Title: A study of the efficacy of cleansers for acne vulgaris.

Journal: The Journal of dermatological treatment 20100501

Title: Effect of neutrase, alcalase, and papain hydrolysis of whey protein concentrates on iron uptake by Caco-2 cells.

Journal: Journal of agricultural and food chemistry 20100428

Title: Effects of a novel pathogenesis-related class 10 (PR-10) protein from Crotalaria pallida Roots with papain inhibitory activity against root-knot nematode Meloidogyne incognita.

Journal: Journal of agricultural and food chemistry 20100414

Title: Behavior of papain in mixed micelles of anionic-cationic surfactants having similar tails and dissimilar head groups.

Journal: Journal of colloid and interface science 20100401

Title: Crystal structure of human cystatin C stabilized against amyloid formation.

Journal: The FEBS journal 20100401

Title: Even-numbered peptides from a papain hydrolysate of silk fibroin.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100315

Title: Cysteine enhances activity and stability of immobilized papain.

Journal: Amino acids 20100301

Title: In silico analysis of sequential, structural and functional diversity of wheat cystatins and its implication in plant defense.

Journal: Genomics, proteomics & bioinformatics 20100301

Title: [Enzymatic production of oral nutritional liquid from oyster].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20100301

Title: Studies in serum support rapid formation of disulfide bond between unpaired cysteine residues in the VH domain of an immunoglobulin G1 molecule.

Journal: Analytical biochemistry 20100201

Title: [Fluorescence spectra analysis of papain structure treated by dynamic high pressure microfluidization in low pressure ranges].

Journal: Guang pu xue yu guang pu fen xi = Guang pu 20100201

Title: Method for studying immunoglobulin G binding on hydrophobic surfaces.

Journal: Langmuir : the ACS journal of surfaces and colloids 20100119

Title: Immobilization of modified papain with anhydride groups on activated cotton fabric.

Journal: Applied biochemistry and biotechnology 20100101

Title: The importance of correct protein concentration for kinetics and affinity determination in structure-function analysis.

Journal: Journal of visualized experiments : JoVE 20100101

Title: Purification and in situ immobilization of papain with aqueous two-phase system.

Journal: PloS one 20100101

Title: [The use of enzymatic hydrolysis for isolation of barbituric acid derivatives from blood (as exemplified by phenobarbital and barbamyl)].

Journal: Sudebno-meditsinskaia ekspertiza 20100101

Title: Challenging a paradigm: theoretical calculations of the protonation state of the Cys25-His159 catalytic diad in free papain.

Journal: Proteins 20091201

Title: A salivary cystatin, HlSC-1, from the ixodid tick Haemaphysalis longicornis play roles in the blood-feeding processes.

Journal: Parasitology research 20091201

Title: Dipeptide-derived nitriles containing additional electrophilic sites: potentially irreversible inhibitors of cysteine proteases.

Journal: Journal of enzyme inhibition and medicinal chemistry 20091201

Title: Two routes for production and purification of Fab fragments in biopharmaceutical discovery research: Papain digestion of mAb and transient expression in mammalian cells.

Journal: Protein expression and purification 20091001

Title: Succinimide formation at Asn 55 in the complementarity determining region of a recombinant monoclonal antibody IgG1 heavy chain.

Journal: Journal of pharmaceutical sciences 20091001

Title: Profiling of calpain activity with a series of FRET-based substrates.

Journal: Biochimica et biophysica acta 20091001

Title: Parathyroid hormone 1-34 inhibits terminal differentiation of human articular chondrocytes and osteoarthritis progression in rats.

Journal: Arthritis and rheumatism 20091001

Title: Sensory crispness of crispy rolls: effect of formulation, storage conditions, and water distribution in the crust.

Journal: Journal of food science 20091001

Title: Identification and characterization of asparagine deamidation in the light chain CDR1 of a humanized IgG1 antibody.

Journal: Analytical biochemistry 20090915

Title: Effects of sodium ferulate on human osteoarthritic chondrocytes and osteoarthritis in rats.

Journal: Clinical and experimental pharmacology & physiology 20090901

Title: Proteomic identification of an MHC-binding peptidome from pancreas and breast cancer cell lines.

Journal: Molecular immunology 20090901

Title: Hydrolytic properties and substrate specificity of the foot-and-mouth disease leader protease.

Journal: Biochemistry 20090825

Title: Polyrotaxane composed of poly-L-lactide and alpha-cyclodextrin exhibiting protease-triggered hydrolysis.

Journal: Biomacromolecules 20090810

Title: Enzymatic synthesis of C-terminal arylamides of amino acids and peptides.

Journal: The Journal of organic chemistry 20090807

Title: eta(1)-N-succinimidato complexes of iron, molybdenum and tungsten as reversible inhibitors of papain.

Journal: Journal of inorganic biochemistry 20090801

Title: Macrocypins, a family of cysteine protease inhibitors from the basidiomycete Macrolepiota procera.

Journal: The FEBS journal 20090801

Title: Proteases induce production of thymic stromal lymphopoietin by airway epithelial cells through protease-activated receptor-2.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20090715

Title: Sulfonation of papain-treated chitosan and its mechanism for anticoagulant activity.

Journal: Carbohydrate research 20090706

Title: Basophils function as antigen-presenting cells for an allergen-induced T helper type 2 response.

Journal: Nature immunology 20090701

Title: Antithrombotic papain-hydrolyzed peptides isolated from pork meat.

Journal: Thrombosis research 20090301

Title: Production and recovery of recombinant propapain with high yield.

Journal: Phytochemistry 20090301

Title: Evaluation of alpha,beta-unsaturated ketone-based probes for papain-family cysteine proteases.

Journal: Bioorganic & medicinal chemistry 20090201

Title: Crystal structure of the parasite inhibitor chagasin in complex with papain allows identification of structural requirements for broad reactivity and specificity determinants for target proteases.

Journal: The FEBS journal 20090201

Title: Close proximity of myosin loop 3 to troponin determined by triangulation of resonance energy transfer distance measurements.

Journal: Biochemistry 20090120

Title: Enantioselective reductive amination of alpha-keto acids by papain-based semisynthetic enzyme.

Journal: Biochemistry. Biokhimiia 20090101

Title: Biocompatibility analysis of chemomechanical caries removal material Papacárie on cultured fibroblasts and subcutaneous tissue.

Journal: Journal of dentistry for children (Chicago, Ill.) 20090101

Title: Two Kunitz-type inhibitors with activity against trypsin and papain from Pithecellobium dumosum seeds: purification, characterization, and activity towards pest insect digestive enzyme.

Journal: Protein and peptide letters 20090101

Title: Biochemical and PMF MALDI-TOF analyses of two novel papain-like plant proteinases.

Journal: Protein and peptide letters 20090101

Title: Antioxidant activities of hydrolysates of Arca subcrenata prepared with three proteases.

Journal: Marine drugs 20081201

Title: Development of immunoaffinity restricted access media for rapid extractions of low-mass analytes.

Journal: Analytical chemistry 20081115

Title: Identifying and characterizing the biological targets of metallotherapeutics: Two approaches using Au(I)-protein interactions as model systems.

Journal: Analytical biochemistry 20081101

Title: Hormone induced changes in lactase glycosylation in developing rat intestine.

Journal: Molecular and cellular biochemistry 20081101

Title: A pulse--radiolysis approach to fast reductive cleavage of a disulfide bond to uncage enzyme activity.

Journal: Free radical biology & medicine 20081101

Title: [Gastric bezoar as complication of gastric banding. Report of one case].

Journal: Revista medica de Chile 20081101

Title: Characterization of inhibitory mechanism and antifungal activity between group-1 and group-2 phytocystatins from taro (Colocasia esculenta).

Journal: The FEBS journal 20081001

Title: Peptidyl epoxides extended in the P' direction as cysteine protease inhibitors: effect on affinity and mechanism of inhibition.

Journal: Bioorganic & medicinal chemistry 20081001

Title: [The enzyme papain in industry and food causes allergic sensitization].

Journal: Ugeskrift for laeger 20080929

Title: Two cysteine proteinase inhibitors from Arabidopsis thaliana, AtCYSa and AtCYSb, increasing the salt, drought, oxidation and cold tolerance.

Journal: Plant molecular biology 20080901

Title: Plant cysteine proteinases: evaluation of the pharmacological activity.

Journal: Phytochemistry 20080901

Title: Beta-lactone probes identify a papain-like peptide ligase in Arabidopsis thaliana.

Journal: Nature chemical biology 20080901

Title: Internalization of cystatin C in human cell lines.

Journal: The FEBS journal 20080901

Title: Fluorescence of primary dentine after chemomechanical and conventional rotary excavation.

Journal: European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry 20080901

Title: Pseudo-esterase activity of human albumin: slow turnover on tyrosine 411 and stable acetylation of 82 residues including 59 lysines.

Journal: The Journal of biological chemistry 20080815

Title: Kinetic characterization and molecular docking of a novel, potent, and selective slow-binding inhibitor of human cathepsin L.

Journal: Molecular pharmacology 20080701

Title: Hybrid protease inhibitors for pest and pathogen control--a functional cost for the fusion partners?

Journal: Plant physiology and biochemistry : PPB 20080701

Title: Molecular docking of cathepsin L inhibitors in the binding site of papain.

Journal: Journal of chemical information and modeling 20080701

Title: [Prokaryotic expression of OC-IdeltaD86 (Oryzacystatin-IdeltaD86) gene and analysis of its activity].

Journal: Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20080701

Title: Characterization of a three-component coupling reaction on proteins by isotopic labeling and nuclear magnetic resonance spectroscopy.

Journal: Journal of the American Chemical Society 20080618

Title: Design, synthesis, and evaluation of inhibitors of cathepsin L: Exploiting a unique thiocarbazate chemotype.

Journal: Bioorganic & medicinal chemistry letters 20080615

Title: Isolation and characterization of a cDNA encoding a papain-like cysteine protease from alfalfa.

Journal: DNA sequence : the journal of DNA sequencing and mapping 20080601

Title: Mass spectrometric and kinetic studies on slow progression of papain-catalyzed polymerization of L-glutamic acid diethyl ester.

Journal: Biochimica et biophysica acta 20080601

Title: Mechanism for stabilization of the molten globule state of papain by sodium n-alkyl sulfates: spectroscopic and calorimetric approaches.

Journal: Journal of colloid and interface science 20080601

Title: Fluorescence anisotropy assay for the traceless kinetic analysis of protein digestion.

Journal: Analytical chemistry 20080601

Title: A conserved poxvirus NlpC/P60 superfamily protein contributes to vaccinia virus virulence in mice but not to replication in cell culture.

Journal: Virology 20080510

Title: Stabilization of scleral collagen by glycerol aldehyde cross-linking.

Journal: Biochimica et biophysica acta 20080501

Title: Glycosylation profiling of a therapeutic recombinant monoclonal antibody with two N-linked glycosylation sites using liquid chromatography coupled to a hybrid quadrupole time-of-flight mass spectrometer.

Journal: Analytical biochemistry 20080415

Title: Free radical scavenging activity of a novel antioxidative peptide purified from hydrolysate of bullfrog skin, Rana catesbeiana Shaw.

Journal: Bioresource technology 20080401

Title: Separation and characterization of the colored material from sugarcane molasses.

Journal: Chemosphere 20080401

Title: Generation of nucleophilic character in the Cys25/His159 ion pair of papain involves Trp177 but not Asp158.

Journal: Biochemistry 20080219

Title: Structural insights into the substrate specificity and activity of ervatamins, the papain-like cysteine proteases from a tropical plant, Ervatamia coronaria.

Journal: The FEBS journal 20080201

Title: The nsp1alpha and nsp1 papain-like autoproteinases are essential for porcine reproductive and respiratory syndrome virus RNA synthesis.

Journal: The Journal of general virology 20080201

Title: Inhibitory activity against papain, a CA1 cysteine peptidase, in Saccharomycetaceae.

Journal: Microbiological research 20080101

Title: 2-[(1-methylpropyl)dithio]-1H-imidazole inhibits tubulin polymerization through cysteine oxidation.

Journal: Molecular cancer therapeutics 20080101

Title: Plant proteases: from phenotypes to molecular mechanisms.

Journal: Annual review of plant biology 20080101

Title: Bovine explant model of degeneration of the intervertebral disc.

Journal: BMC musculoskeletal disorders 20080101

Title: Evaluation of residual dentin after conventional and chemomechanical caries removal using SEM.

Journal: The Journal of clinical pediatric dentistry 20080101

Title: Azadipeptide nitriles: highly potent and proteolytically stable inhibitors of papain-like cysteine proteases.

Journal: Angewandte Chemie (International ed. in English) 20080101

Title: Enzymatic wound debridement.

Journal: Journal of wound, ostomy, and continence nursing : official publication of The Wound, Ostomy and Continence Nurses Society 20080101

Title: Strategies for addressing restorative challenges in HIV-infected children.

Journal: Journal of dentistry for children (Chicago, Ill.) 20080101

Title: Chemo-mechanical removal of caries in an adolescent patient using a papain gel: case report.

Journal: The Journal of clinical pediatric dentistry 20080101

Title: Papain adulteration in 11-nor-Delta9-tetrahydrocannabinol- 9-carboxylic acid-positive urine samples.

Journal: Journal of analytical toxicology 20080101

Title: [Chemoenzymatic synthesis of new fluorogenous substrates for cysteine proteases of the papain family].

Journal: Bioorganicheskaia khimiia 20080101

Title: Papain-like cysteine proteases: key players at molecular battlefields employed by both plants and their invaders.

Journal: Molecular plant pathology 20080101

Title: [Isolation of blood caffeine as a model substance by enzymatic hydrolysis].

Journal: Sudebno-meditsinskaia ekspertiza 20080101

Title: Albumin competitively inhibits glycation of less abundant proteins.

Journal: Protein and peptide letters 20080101

Title: [Study of therapeutic effect and mechanism of Sihuang powder treating acute synovitis in experimental rabbit induced by papain injection].

Journal: Zhongguo gu shang = China journal of orthopaedics and traumatology 20080101

Title: Inhibition of ice crystal growth in ice cream mix by gelatin hydrolysate.

Journal: Journal of agricultural and food chemistry 20071226

Title: GrpE N-terminal domain contributes to the interaction with Dnak and modulates the dynamics of the chaperone substrate binding domain.

Journal: Journal of molecular biology 20071207

Title: [Fluorescence spectra analysis of papain treated by pulsed electric field].

Journal: Guang pu xue yu guang pu fen xi = Guang pu 20071201

Title: Synthesis and evaluation of chloromethyl sulfoxides as a new class of selective irreversible cysteine protease inhibitors.

Journal: Bioorganic & medicinal chemistry 20071115

Title: Mechanism of solvent induced thermal stabilization of papain.

Journal: International journal of biological macromolecules 20071001

Title: Physicochemical and bitterness properties of enzymatic pea protein hydrolysates.

Journal: Journal of food science 20071001

Title: Pore-size tunable mesoporous zirconium organophosphonates with chiral L-proline for enzyme adsorption.

Journal: Inorganic chemistry 20070917

Title: Analysis of post-translational modifications in recombinant monoclonal antibody IgG1 by reversed-phase liquid chromatography/mass spectrometry.

Journal: Journal of chromatography. A 20070914

Title: Preparation of hydrophilic polyhydroxyalkyl glutamine crosslinked films and its biodegradability.

Journal: Journal of biomaterials applications 20070901

Title: Purification of a cysteine protease inhibitor from larval hemolymph of the tobacco hornworm (Manduca sexta) and functional expression of the recombinant protein.

Journal: Insect biochemistry and molecular biology 20070901

Title: Enzymatic hydrolysis of heated whey: iron-binding ability of peptides and antigenic protein fractions.

Journal: Journal of dairy science 20070901

Title: Antitumor effects in vitro and in vivo and mechanisms of protection against melanoma B16F10-Nex2 cells by fastuosain, a cysteine proteinase from Bromelia fastuosa.

Journal: Neoplasia (New York, N.Y.) 20070901

Title: Domain organization and movements in heavy metal ion pumps: papain digestion of CopA, a Cu+-transporting ATPase.

Journal: The Journal of biological chemistry 20070831

Title: The 1,4-naphthoquinone scaffold in the design of cysteine protease inhibitors.

Journal: Bioorganic & medicinal chemistry 20070801

Title: The catalytic mode of cysteine proteinases of papain (C1) family.

Journal: Bioresource technology 20070701

Title: Cloning and characterisation of the Anisakis simplex allergen Ani s 4 as a cysteine-protease inhibitor.

Journal: International journal for parasitology 20070701

Title: Effect of polyethylene glycols on the function and structure of thiol proteases.

Journal: Journal of biochemistry 20070701

Title: Carboxy terminal extended phytocystatins are bifunctional inhibitors of papain and legumain cysteine proteinases.

Journal: FEBS letters 20070626

Title: Application of recombinant chum salmon cystatin to Alaska pollock (Theragra chalcogramma) surimi to prevent gel weakening.

Journal: Journal of food science 20070601

Title: Multiple domains of endopin 2A for serpin cross-class inhibition of papain.

Journal: Archives of biochemistry and biophysics 20070515

Title: Effects of knee injection on skeletal muscle metabolism and contractile force in rats.

Journal: Osteoarthritis and cartilage 20070501

Title: Structure of the mexicain-E-64 complex and comparison with other cysteine proteases of the papain family.

Journal: Acta crystallographica. Section D, Biological crystallography 20070501

Title: Design, synthesis, and evaluation of in vivo potency and selectivity of epoxysuccinyl-based inhibitors of papain-family cysteine proteases.

Journal: Chemistry & biology 20070501

Title: [Resonance scattering spectral assay of papain enzymatic activity with sodium dodecyl benzene sulfonate].

Journal: Guang pu xue yu guang pu fen xi = Guang pu 20070501

Title: Active fragments of the antihemorrhagic protein HSF from serum of habu (Trimeresurus flavoviridis).

Journal: Toxicon : official journal of the International Society on Toxinology 20070401

Title: Bicyclic carbamates as inhibitors of papain-like cathepsin proteases.

Journal: Bioorganic & medicinal chemistry letters 20070301

Title: Effect of both ultraviolet B irradiation and histamine receptor function on allergic responses to an inhaled antigen.

Journal: Journal of immunology (Baltimore, Md. : 1950) 20070301

Title: Characterization of hydrolysates derived from enzymatic hydrolysis of wheat gluten.

Journal: Journal of food science 20070301

Title: Cysteine-specific, covalent anchoring of transition organometallic complexes to the protein papain from Carica papaya.

Journal: Chembiochem : a European journal of chemical biology 20070122

Title: Anthelmintic action of plant cysteine proteinases against the rodent stomach nematode, Protospirura muricola, in vitro and in vivo.

Journal: Parasitology 20070101

Title: Secretion and processing of a novel multi-domain cystatin-like protein by intracellular stages of Trichinella spiralis.

Journal: Molecular and biochemical parasitology 20070101

Title: A Phytophthora infestans cystatin-like protein targets a novel tomato papain-like apoplastic protease.

Journal: Plant physiology 20070101

Title: A silicone-based controlled-release device for accelerated proteolytic debridement of wounds.

Journal: Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 20070101

Title: Heterogeneity of proteinase inhibitors in the water-soluble organic matrix from the oyster nacre.

Journal: Marine biotechnology (New York, N.Y.) 20070101

Title: Aerosol probes of emphysema progression in dogs treated with all trans retinoic acid--an exploratory study.

Journal: Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine 20070101

Title: Chemical versus conventional caries removal techniques in primary teeth: a microhardness study.

Journal: The Journal of clinical pediatric dentistry 20070101

Title: Role of sulfhydryl groups in transfection? A case study with chitosan-NAC nanoparticles.

Journal: Bioconjugate chemistry 20070101

Title: Fc glycans terminated with N-acetylglucosamine residues increase antibody resistance to papain.

Journal: Biotechnology progress 20070101

Title: The Surface Plasmon Resonance Imaging sensor for papain based on immobilized cystatin.

Journal: Protein and peptide letters 20070101

Title: Purification and characterization of a trypsin-papain inhibitor from Pithecelobium dumosum seeds and its in vitro effects towards digestive enzymes from insect pests.

Journal: Plant physiology and biochemistry : PPB 20070101

Title: Influence of papain urea copper chlorophyllin on wound matrix remodeling.

Journal: Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 20070101

Title: [Ubiquitin causes selective increase in the sensitivity of rat brain mitochondrial monoamine oxidases to various proteases].

Journal: Biomeditsinskaia khimiia 20070101

Title: In vitro study of the effectiveness of different dressings for debriding fibrin in blood clots from horses.

Journal: The Veterinary record 20061118

Title: Kosmotropic salt activation and substrate specificity of poliovirus protease 3C.

Journal: Biochemistry 20061003

Title: Meat tenderizing effect of injecting encapsulated Ca2+ in liposome into rabbit before slaughter.

Journal: Bioscience, biotechnology, and biochemistry 20061001

Title: Characterization of partially folded intermediates of papain in presence of cationic, anionic, and nonionic detergents at low pH.

Journal: Biopolymers 20060901

Title: Evidence for inactivation of cysteine proteases by reactive carbonyls via glycation of active site thiols.

Journal: The Biochemical journal 20060901

Title: Molecular cloning, sequencing, expression of Chinese sturgeon cystatin in yeast Pichia pastoris and its proteinase inhibitory activity.

Journal: Journal of biotechnology 20060901

Title: Antioxidant activity of zein hydrolysates in a liposome system and the possible mode of action.

Journal: Journal of agricultural and food chemistry 20060809

Title: Dipeptide vinyl sultams: synthesis via the Wittig-Horner reaction and activity against papain, falcipain-2 and Plasmodium falciparum.

Journal: Bioorganic & medicinal chemistry letters 20060801

Title: Mutagenic definition of a papain-like catalytic triad, sufficiency of the N-terminal domain for single-site core catalytic enzyme acylation, and C-terminal domain for augmentative metal activation of a eukaryotic phytochelatin synthase.

Journal: Plant physiology 20060701

Title: Recombinant expression, purification, and functional analysis of two novel cystatins from sugarcane (Saccharum officinarum).

Journal: Protein expression and purification 20060601

Title: Novel aza peptide inhibitors and active-site probes of papain-family cysteine proteases.

Journal: Chembiochem : a European journal of chemical biology 20060601

Title: High-resolution complex of papain with remnants of a cysteine protease inhibitor derived from Trypanosoma brucei.

Journal: Acta crystallographica. Section F, Structural biology and crystallization communications 20060601

Title: Temperature-dependences of the kinetics of reactions of papain and actinidin with a series of reactivity probes differing in key molecular recognition features.

Journal: The Biochemical journal 20060515

Title: Structure determination of neoefrapeptins A to N: peptides with insecticidal activity produced by the fungus Geotrichum candidum.

Journal: The Journal of antibiotics 20060501

Title: Crystal structure of a papain-fold protein without the catalytic residue: a novel member in the cysteine proteinase family.

Journal: Journal of molecular biology 20060421

Title: Stability of protease in organic solvent: structural identification by solid-state NMR of lyophilized papain before and after 1-propanol treatment and the corresponding enzymatic activities.

Journal: Biotechnology and bioengineering 20060405

Title: Managing a traumatic wound in a geriatric patient.

Journal: Ostomy/wound management 20060401

Title: Modulating the sensory response of a conjugated polymer by proteins: an agglutination assay for mercury ions in water.

Journal: Journal of the American Chemical Society 20060308

Title: The structure of Leishmania mexicana ICP provides evidence for convergent evolution of cysteine peptidase inhibitors.

Journal: The Journal of biological chemistry 20060303

Title: Characterization of the acidic and basic limbs of a bell-shaped pH profile in the inhibitory activity of bromelain inhibitor VI.

Journal: Biopolymers 20060301

Title: Micronuclei evaluation of reduction in neoadjuvant chemotherapy related acute toxicity in locally advanced lung cancer: an indian experience.

Journal: The Journal of the Association of Physicians of India 20060301

Title: Quantifying the protein core flexibility through analysis of cavity formation.

Journal: The Journal of chemical physics 20060221

Title: Loosely packed papain prosegment displays inhibitory activity.

Journal: Archives of biochemistry and biophysics 20060215

Title: Crystal structure of group A streptococcus Mac-1: insight into dimer-mediated specificity for recognition of human IgG.

Journal: Structure (London, England : 1993) 20060201

Title: Purification and characterization of extracellular cysteine protease inhibitor, ECPI-2, from Chlorella sp.

Journal: Journal of bioscience and bioengineering 20060201

Title: [Impact on the model of rat osteoarthritis of jingu tablet].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060201

Title: Purification and characterization of novel proteinase inhibitors from dried figs.

Journal: Journal of agricultural and food chemistry 20060125

Title: The effects of chemical and heat maceration techniques on the recovery of nuclear and mitochondrial DNA from bone.

Journal: Journal of forensic sciences 20060101

Title: Antioxidant properties of enzymatic hydrolysates from royal jelly.

Journal: Journal of medicinal food 20060101

Title: Deubiquitinating activity of the SARS-CoV papain-like protease.

Journal: Advances in experimental medicine and biology 20060101

Title: Relative delivery efficiency and convenience of spray and ointment formulations of papain/urea/chlorophyllin enzymatic wound therapies.

Journal: Journal of wound, ostomy, and continence nursing : official publication of The Wound, Ostomy and Continence Nurses Society 20060101

Title: Inhibition of mammalian cathepsins by Plesiomonas shigelloides.

Journal: Folia microbiologica 20060101

Title: A reminder that ZZAP reagent removes complement in addition to IgG from coated RBCs.

Journal: Immunohematology 20060101

Title: Structural basis for the specificity and catalysis of human Atg4B responsible for mammalian autophagy.

Journal: The Journal of biological chemistry 20051202

Title: Cystatins may confer viral resistance in plants by inhibition of a virus-induced cell death phenomenon in which cysteine proteinases are active: cloning and molecular characterization of a cDNA encoding cysteine-proteinase inhibitor (celostatin) from Celosia cristata (crested cock's comb).

Journal: Biotechnology and applied biochemistry 20051201

Title: Isolation, characterization and kinetics of goat cystatins.

Journal: Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20051201

Title: Interaction of papain-like cysteine proteases with dipeptide-derived nitriles.

Journal: Journal of medicinal chemistry 20051201

Title: Comparing two commercial enzymes to estimate in vitro proteolysis of purified or semi-purified proteins.

Journal: Journal of animal physiology and animal nutrition 20051201

Title: Benzodioxole derivatives as negative effectors of plant proteases.

Journal: Journal of agricultural and food chemistry 20050921

Title: A new multi-domain member of the cystatin superfamily expressed by Fasciola hepatica.

Journal: International journal for parasitology 20050901

Title: [Oriented immobilization of papain on metal chelating carriers].

Journal: Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20050901

Title: Papain-like protease 2 (PLP2) from severe acute respiratory syndrome coronavirus (SARS-CoV): expression, purification, characterization, and inhibition.

Journal: Biochemistry 20050802

Title: Affinity selection to papain yields potent peptide inhibitors of cathepsins L, B, H, and K.

Journal: Biochemical and biophysical research communications 20050708

Title: Light-induced inhibition of papain by a {Mn-NO}6 nitrosyl: identification of papain-SNO adduct by mass spectrometry.

Journal: Journal of inorganic biochemistry 20050701

Title: Fluorogenic peptide substrates containing benzoxazol-5-yl-alanine derivatives for kinetic assay of cysteine proteases.

Journal: Analytical biochemistry 20050701

Title: New non-peptidic inhibitors of papain derived from etacrynic acid.

Journal: Medicinal chemistry (Shariqah (United Arab Emirates)) 20050701

Title: Synthesis and evaluation of isatin derivatives as effective SARS coronavirus 3CL protease inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20050615

Title: Papain entrapment in alginate beads for stability improvement and site-specific delivery: physicochemical characterization and factorial optimization using neural network modeling.

Journal: AAPS PharmSciTech 20050601

Title: The novel bovine serpin endopin 2C demonstrates selective inhibition of the cysteine protease cathepsin L compared to the serine protease elastase, in cross-class inhibition.

Journal: Biochemistry 20050531

Title: A serine proteinase inhibitor isolated from Tamarindus indica seeds and its effects on the release of human neutrophil elastase.

Journal: Life sciences 20050506

Title: Solid-phase synthesis of double-headed epoxysuccinyl activity-based probes for selective targeting of papain family cysteine proteases.

Journal: Chembiochem : a European journal of chemical biology 20050501

Title: A novel cysteine protease inhibitor with lectin activity from the epidermis of the Japanese eel Anguilla japonica.

Journal: Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20050501

Title: Pantothenic acid quantification: method comparison of a stable isotope dilution assay and a microbiological assay.

Journal: International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20050501

Title: Cysteines in CH1 underlie retention of unassembled Ig heavy chains.

Journal: The Journal of biological chemistry 20050415

Title: Nitric oxide-related species-induced protein oxidation: reversible, irreversible, and protective effects on enzyme function of papain.

Journal: Free radical biology & medicine 20050415

Title: Enzymic asymmetric hydrolysis of D,L-p-hydroxyphenylglycine methyl ester in aqueous ionic liquid co-solvent mixtures.

Journal: Biotechnology and applied biochemistry 20050401

Title: 1,2,5-Thiadiazolidin-3-one 1,1-dioxide-based heterocyclic sulfides are potent inhibitors of human tryptase.

Journal: Archives of biochemistry and biophysics 20050401

Title: Development and pharmacological characterization of a rat model of osteoarthritis pain.

Journal: Pain 20050401

Title: Characterization of recombinant amyloidogenic chicken cystatin mutant I66Q expressed in yeast.

Journal: Journal of biochemistry 20050401

Title: Conformational study of papain in the presence of sodium dodecyl sulfate in aqueous medium.

Journal: Colloids and surfaces. B, Biointerfaces 20050325

Title: Identification of EhICP1, a chagasin-like cysteine protease inhibitor of Entamoeba histolytica.

Journal: FEBS letters 20050314

Title: Purification and determination of inhibitory activity of recombinant soyacystatin for surimi application.

Journal: Molecular nutrition & food research 20050301

Title: [The study on the treatment of Oviducts Ranae protein with enzyme hydrolysis].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050301

Title: Antioxidative ability in a linoleic acid oxidation system and scavenging abilities against active oxygen species of enzymatic hydrolysates from pollen Cistus ladaniferus.

Journal: International journal of molecular medicine 20050201

Title: The biphasic response of porcine tendon to recombinant porcine growth hormone.

Journal: Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 20050201

Title: Assessment of the anthelmintic effect of natural plant cysteine proteinases against the gastrointestinal nematode, Heligmosomoides polygyrus, in vitro.

Journal: Parasitology 20050201

Title: Dissociation enzyme effects on the potassium currents of inner hair cells isolated from guinea-pig cochlea.

Journal: Hearing research 20050101

Title: Exfoliation of Helicobacter pylori from gastric mucin by glycopolypeptides from buttermilk.

Journal: Journal of dairy science 20050101

Title: 2 devices that unclog feeding tubes.

Journal: RN 20050101

Title: Antioxidant activity and angiotensin I-converting enzyme inhibition by enzymatic hydrolysates from bee bread.

Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20050101

Title: Papain: a novel urine adulterant.

Journal: Journal of analytical toxicology 20050101

Title: Papain gel: a new chemo-mechanical caries removal agent.

Journal: The Journal of clinical pediatric dentistry 20050101

Title: Characterization of a partially folded intermediate of papain induced by fluorinated alcohols at low pH.

Journal: Archives of biochemistry and biophysics 20041201

Title: Neural stem cell differentiation in a cell-collagen-bioreactor culture system.

Journal: Brain research. Developmental brain research 20041125

Title: A multicystatin is induced by drought-stress in cowpea (Vigna unguiculata (L.) Walp.) leaves.

Journal: FEBS letters 20041119

Title: Crystal structures of calpain-E64 and -leupeptin inhibitor complexes reveal mobile loops gating the active site.

Journal: Journal of molecular biology 20041105

Title: The effects of Panafil when using topical negative pressure to heal an infected sternal wound.

Journal: Journal of wound care 20041101

Title: Inhibitory effects of cystatins on proteolytic activities of the Plum pox potyvirus cysteine proteinases.

Journal: Virus research 20041001

Title: Two polymorphs of a covalent complex between papain and a diazomethylketone inhibitor.

Journal: The journal of peptide research : official journal of the American Peptide Society 20041001

Title: ECEPE proteins: a novel family of eukaryotic cysteine proteinases.

Journal: Trends in biochemical sciences 20041001

Title: Foot-and-mouth disease virus leader proteinase: specificity at the P2 and P3 positions and comparison with other papain-like enzymes.

Journal: Biochemistry 20040914

Title: Structural basis of protein kinetic stability: resistance to sodium dodecyl sulfate suggests a central role for rigidity and a bias toward beta-sheet structure.

Journal: Biochemistry 20040907

Title: Weeds, worms, and more. Papain's long-lost cousin, phytochelatin synthase.

Journal: Plant physiology 20040901

Title: Cathepsin V, a novel and potent elastolytic activity expressed in activated macrophages.

Journal: The Journal of biological chemistry 20040827

Title: BTLCP proteins: a novel family of bacterial transglutaminase-like cysteine proteinases.

Journal: Trends in biochemical sciences 20040801

Title: Total enzymatic synthesis of cholecystokinin CCK-5.

Journal: Amino acids 20040801

Title: Molecular cloning, expression, and functional characterization of a cystatin from pineapple stem.

Journal: Bioscience, biotechnology, and biochemistry 20040801

Title: Drosophila long-term memory formation involves regulation of cathepsin activity.

Journal: Nature 20040722

Title: Probing the mechanism of hamster arylamine N-acetyltransferase 2 acetylation by active site modification, site-directed mutagenesis, and pre-steady state and steady state kinetic studies.

Journal: Biochemistry 20040629

Title: Prevention of domain swapping inhibits dimerization and amyloid fibril formation of cystatin C: use of engineered disulfide bridges, antibodies, and carboxymethylpapain to stabilize the monomeric form of cystatin C.

Journal: The Journal of biological chemistry 20040604

Title: Proteinases participating in the processing and activation of prolegumain in primary cultured rat macrophages.

Journal: Biological chemistry 20040601

Title: Method for bacterial expression and purification of sesame cystatin via artificial oil bodies.

Journal: Journal of agricultural and food chemistry 20040519

Title: A Kunitz-type inhibitor of coleopteran proteases, isolated from Adenanthera pavonina L. seeds and its effect on Callosobruchus maculatus.

Journal: Journal of agricultural and food chemistry 20040505

Title: Myosin regulatory domain orientation in skeletal muscle fibers: application of novel electron paramagnetic resonance spectral decomposition and molecular modeling methods.

Journal: Biophysical journal 20040501

Title: Kinetics of parasite cysteine proteinase inactivation by NO-donors.

Journal: Biochemical and biophysical research communications 20040312

Title: Isomerization of the uncomplexed actinidin molecule: kinetic accessibility of additional steps in enzyme catalysis provided by solvent perturbation.

Journal: The Biochemical journal 20040301

Title: The N-terminus moiety of the cystatin SmCys from Schistosoma mansoni regulates its inhibitory activity in vitro and in vivo.

Journal: Molecular and biochemical parasitology 20040301

Title: Debridement: controlling the necrotic/cellular burden.

Journal: Advances in skin & wound care 20040301

Title: Sequential Development of Cysteine Proteinase Activities and Gene Expression during Somatic Embryogenesis in Carrot.

Journal: Bioscience, biotechnology, and biochemistry 20040301

Title: [Immobilization and stabilization of papain on SiO2 particles containing amine groups].

Journal: Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20040301

Title: Structural basis of the unusual stability and substrate specificity of ervatamin C, a plant cysteine protease from Ervatamia coronaria.

Journal: Biochemistry 20040217

Title: Regulation of collagenase activities of human cathepsins by glycosaminoglycans.

Journal: The Journal of biological chemistry 20040213

Title: The ribbon of hydrogen bonds in globular proteins. IV. The example of the papain family.

Journal: Biopolymers 20040205

Title: Production and activation of recombinant papain-like cysteine proteases.

Journal: Methods (San Diego, Calif.) 20040201

Title: Papain protects papaya trees from herbivorous insects: role of cysteine proteases in latex.

Journal: The Plant journal : for cell and molecular biology 20040201

Title: Thiirancarboxamides as inhibitors of papain.

Journal: Archiv der Pharmazie 20040201

Title: Effect of water-soluble phospholipid polymers conjugated with papain on the enzymatic stability.

Journal: Biomaterials 20040101

Title: Activity of immobilized papain dehydrated by n-propanol in low-water media.

Journal: Biotechnology letters 20040101

Title: Molecular and biochemical assays of cartilage components.

Journal: Methods in molecular medicine 20040101

Title: Insight into catalytic mechanism of papain-like cysteine proteinases: the case of D158.

Journal: Applied biochemistry and biotechnology 20040101

Title: Characterization of free aromatic amino acids and estimation of exposition rate of phenylalanine in casein hydrolysates by second derivative spectrophotometry.

Journal: Acta cientifica venezolana 20040101

Title: Murine pneumotropic virus VP1 virus-like particles (VLPs) bind to several cell types independent of sialic acid residues and do not serologically cross react with murine polyomavirus VP1 VLPs.

Journal: The Journal of general virology 20031201

Title: Enzymic, phylogenetic, and structural characterization of the unusual papain-like protease domain of Plasmodium falciparum SERA5.

Journal: The Journal of biological chemistry 20031128

Title: Inhibitory mechanism of a cross-class serpin, the squamous cell carcinoma antigen 1.

Journal: The Journal of biological chemistry 20031114

Title: Purification and properties of cysteine proteinase inhibitors from rabbit skeletal muscle.

Journal: Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20031001

Title: Grafting of features of cystatins C or B into the N-terminal region or second binding loop of cystatin A (stefin A) substantially enhances inhibition of cysteine proteinases.

Journal: Biochemistry 20030930

Title: Applying the increase in rate constants of cooperative proteolysis to the determination of transition curves of protein denaturation.

Journal: Journal of biochemical and biophysical methods 20030930

Title: Ca2+ binding to myosin regulatory light chain affects the conformation of the N-terminus of essential light chain and its binding to actin.

Journal: Archives of biochemistry and biophysics 20030915

Title: Mechanisms and enzymes involved in SARS coronavirus genome expression.

Journal: The Journal of general virology 20030901

Title: Electrostatic properties in the catalytic site of papain: A possible regulatory mechanism for the reactivity of the ion pair.

Journal: Proteins 20030801

Title: Processing and subcellular localization of the leader papain-like proteinase of Beet yellows closterovirus.

Journal: The Journal of general virology 20030801

Title: Inhibition of papain-like cysteine proteases and legumain by caspase-specific inhibitors: when reaction mechanism is more important than specificity.

Journal: Cell death and differentiation 20030801

Title: Nontraditional wound care: A review of the evidence for the use of sugar, papaya/papain, and fatty acids.

Journal: Journal of wound, ostomy, and continence nursing : official publication of The Wound, Ostomy and Continence Nurses Society 20030701

Title: Novel bi- and trifunctional inhibitors of tumor-associated proteolytic systems.

Journal: Biological chemistry 20030701

Title: Variation in the pH-dependent pre-steady-state and steady-state kinetic characteristics of cysteine-proteinase mechanism: evidence for electrostatic modulation of catalytic-site function by the neighbouring carboxylate anion.

Journal: The Biochemical journal 20030615

Title: Antioxidant activity of peptides obtained from porcine myofibrillar proteins by protease treatment.

Journal: Journal of agricultural and food chemistry 20030604

Title: AtCYS1, a cystatin from Arabidopsis thaliana, suppresses hypersensitive cell death.

Journal: European journal of biochemistry 20030601

Title: Enzymatic synthesis and characterization of l-methionine and 2-hydroxy-4-(methylthio)butanoic acid (HMB) co-oligomers.

Journal: Journal of agricultural and food chemistry 20030423

Title: Enzymatic synthesis of a CCK-4 tripeptide fragment.

Journal: Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20030401

Title: Human eosinophils are activated by cysteine proteases and release inflammatory mediators.

Journal: The Journal of allergy and clinical immunology 20030401

Title: Proteolytic enzyme conjugated to SC-glucan as an enzymatic transdermal drug penetration enhancer.

Journal: Die Pharmazie 20030401

Title: Versatility of selenium catalysis in PHGPx unraveled by LC/ESI-MS/MS.

Journal: Biological chemistry 20030401

Title: [X-ray microanalysis of the activity of immobilized papain].

Journal: Guang pu xue yu guang pu fen xi = Guang pu 20030401

Title: The cystatin-related epididymal spermatogenic protein inhibits the serine protease prohormone convertase 2.

Journal: Endocrinology 20030301

Title: N-terminal domain unfolds first in the sequential unfolding of papain.

Journal: Protein and peptide letters 20030201

Title: Contributions of individual residues in the N-terminal region of cystatin B (stefin B) to inhibition of cysteine proteinases.

Journal: Biochimica et biophysica acta 20030131

Title: Oriented versus random protein immobilization.

Journal: Journal of biochemical and biophysical methods 20030131

Title: Frog saccular hair cells dissociated with protease VIII exhibit inactivating BK currents, K(V) currents, and low-frequency electrical resonance.

Journal: Hearing research 20030101

Title: Morrenain b I, a papain-like endopeptidase from the latex of Morrenia brachystephana Griseb. (Asclepiadaceae).

Journal: Journal of protein chemistry 20030101

Title: New cysteine protease inhibitors in physiological secretory fluids and their medical significance.

Journal: Advances in enzyme regulation 20030101

Title: Properties of chemically oxidized kininogens.

Journal: Acta biochimica Polonica 20030101

Title: Papain-like lysosomal cysteine proteases and their inhibitors: drug discovery targets?

Journal: Biochemical Society symposium 20030101

Title: [Interaction of human factor X with thromboplastin].

Journal: Biomeditsinskaia khimiia 20030101

Title: Design and synthesis of 6-substituted amino-4-oxa-1-azabicyclo[3,2,0]heptan-7-one derivatives as cysteine proteases inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20021202

Title: Human and parasitic papain-like cysteine proteases: their role in physiology and pathology and recent developments in inhibitor design.

Journal: Chemical reviews 20021201

Title: Occurrence and structural characterization of versican-like proteoglycan in human vitreous.

Journal: Biochimie 20021201

Title: [The preparation and identification of rabbit's antibody of chymopapain].

Journal: Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20021201

Title: Critical role of amino acid 23 in mediating activity and specificity of vinckepain-2, a papain-family cysteine protease of rodent malaria parasites.

Journal: The Biochemical journal 20021115

Title: Overlapping binding sites for trypsin and papain on a Kunitz-type proteinase inhibitor from Prosopis juliflora.

Journal: Proteins 20021115

Title: Aza-peptide epoxides: a new class of inhibitors selective for clan CD cysteine proteases.

Journal: Journal of medicinal chemistry 20021107

Title: Preparation and characterization of papain-modified sesame (Sesamum indicum L.) protein isolates.

Journal: Journal of agricultural and food chemistry 20021106

Title: Protein engineering of nitrile hydratase activity of papain: molecular dynamics study of a mutant and wild-type enzyme.

Journal: Journal of the American Chemical Society 20021106

Title: A randomized paired comparison trial of cutaneous treatments for acute jellyfish (Carybdea alata) stings.

Journal: The American journal of emergency medicine 20021101

Title: Application potency of engineered G159 mutants on P1 substrate pocket of subtilisin YaB as improved meat tenderizers.

Journal: Journal of agricultural and food chemistry 20021009

Title: Small molecule affinity fingerprinting. A tool for enzyme family subclassification, target identification, and inhibitor design.

Journal: Chemistry & biology 20021001

Title: Foot-and-mouth disease virus leader proteinase: a papain-like enzyme requiring an acidic environment in the active site.

Journal: FEBS letters 20020925

Title: Enhancement of proteinase inhibitory activity of recombinant human cystatin C using random-centroid optimization.

Journal: Biochimica et biophysica acta 20020923

Title: The crystal structure of human cathepsin F and its implications for the development of novel immunomodulators.

Journal: Journal of molecular biology 20020920

Title: A 13C-NMR study of the inhibition of papain by a dipeptide-glyoxal inhibitor.

Journal: The Biochemical journal 20020915

Title: Azapeptides structurally based upon inhibitory sites of cystatins as potent and selective inhibitors of cysteine proteases.

Journal: Journal of medicinal chemistry 20020912

Title: Cysteine proteinase inhibitors in elapid and hydrophiid snake venoms.

Journal: Toxicon : official journal of the International Society on Toxinology 20020901

Title: The novel serpin endopin 2 demonstrates cross-class inhibition of papain and elastase: localization of endopin 2 to regulated secretory vesicles of neuroendocrine chromaffin cells.

Journal: Biochemistry 20020820

Title: Production, properties and specificity of a new bacterial L-fucose- and D-arabinose-binding lectin of the plant aggressive pathogen Ralstonia solanacearum, and its comparison to related plant and microbial lectins.

Journal: Journal of biochemistry 20020801

Title: Inhibition of cathepsin K with lysosomotropic macromolecular inhibitors.

Journal: Biochemistry 20020716

Title: Enzymatic hydrolysis of nitriles by an engineered nitrile hydratase (papain Gln19Glu) in aqueous-organic media.

Journal: Biotechnology and bioengineering 20020705

Title: Quick measurement of protein sulfhydryls with Ellman's reagent and with 4,4'-dithiodipyridine.

Journal: Analytical and bioanalytical chemistry 20020701

Title: Interim analysis of a prospective, randomized trial of vacuum-assisted closure versus the healthpoint system in the management of pressure ulcers.

Journal: Annals of plastic surgery 20020701

Title: Calcium modulates protease resistance and carbohydrate binding of a plant defense legume lectin, Griffonia simplicifolia lectin II (GSII).

Journal: Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20020601

Title: Affinity of chicken cystatin for S-(carbamoylmethyl)-papain, measured by fluorescence at acidic pH.

Journal: Protein and peptide letters 20020601

Title: Effect of urea at lower concentration on the structure of papain--formation of a stable molten globule and its characterization.

Journal: Indian journal of biochemistry & biophysics 20020601

Title: The 45 kDa collagen-binding fragment of fibronectin induces matrix metalloproteinase-13 synthesis by chondrocytes and aggrecan degradation by aggrecanases.

Journal: The Biochemical journal 20020515

Title: Modulation of the electrostatic charge at the active site of foot-and-mouth-disease-virus leader proteinase, an unusual papain-like enzyme.

Journal: The Biochemical journal 20020501

Title: Galactosaminoglycan composition in chicken eggshell.

Journal: Poultry science 20020501

Title: A 40-kDa polypeptide from papain digestion of the rabbit intestinal Na+/phosphate cotransporter retains Na+ and phosphate cotransport.

Journal: Archives of biochemistry and biophysics 20020501

Title: Red blood cells stimulate fibroblast-mediated contraction of three dimensional collagen gels in co-culture.

Journal: Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20020501

Title: Are PhAcOZ and Nsc suitable N alpha-protecting groups for protease-catalysed peptide synthesis?

Journal: Die Pharmazie 20020501

Title: Evidence that serpin architecture intrinsically supports papain-like cysteine protease inhibition: engineering alpha(1)-antitrypsin to inhibit cathepsin proteases.

Journal: Biochemistry 20020416

Title: Inhibitory activity of a heterochromatin-associated serpin (MENT) against papain-like cysteine proteinases affects chromatin structure and blocks cell proliferation.

Journal: The Journal of biological chemistry 20020412

Title: Conformational analysis of the GTP-binding protein MxA using limited proteolysis.

Journal: FEBS letters 20020410

Title: Topology of the anion exchange protein AE1: the controversial sidedness of lysine 743.

Journal: Biochemistry 20020312

Title: [Characterization of peptide and amino acid profile in casein hydrolysates].

Journal: Archivos latinoamericanos de nutricion 20020301

Title: Cholesterol is an important factor affecting the membrane insertion of beta-amyloid peptide (A beta 1-40), which may potentially inhibit the fibril formation.

Journal: The Journal of biological chemistry 20020222

Title: Stabilization of molten globule state of papain by urea.

Journal: Biochemical and biophysical research communications 20020208

Title: Cysteine protease gene expression and proteolytic activity during senescence of Alstroemeria petals.

Journal: Journal of experimental botany 20020201

Title: Effect of metal ions on structure and activity of papain from Carica papaya.

Journal: Die Nahrung 20020201

Title: A multivalent assay to detect glycosaminoglycan, protein, collagen, RNA, and DNA content in milligram samples of cartilage or hydrogel-based repair cartilage.

Journal: Analytical biochemistry 20020101

Title: The Arabidopsis xylem peptidase XCP1 is a tracheary element vacuolar protein that may be a papain ortholog.

Journal: Plant physiology 20020101

Title: Characterizing closely spaced, complex disulfide bond patterns in peptides and proteins by liquid chromatography/electrospray ionization tandem mass spectrometry.

Journal: Journal of mass spectrometry : JMS 20020101

Title: Protease-catalyzed regioselective polymerization and copolymerization of glutamic acid diethyl ester.

Journal: Biomacromolecules 20020101

Title: Cysteine peptidases of mammals: their biological roles and potential effects in the oral cavity and other tissues in health and disease.

Journal: Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists 20020101

Title: The effects of the interaction of myosin essential light chain isoforms with actin in skeletal muscles.

Journal: Acta biochimica Polonica 20020101

Title: Synthesis and biological properties of antitumor-active conjugates of ADR with dextran.

Journal: Journal of biomaterials science. Polymer edition 20020101

Title: Salivary (SD-type) cystatins: over one billion years in the making--but to what purpose?

Journal: Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists 20020101

Title: [Effect of shenmai injection and aminophylline on small airway smooth muscle cell apoptosis and related gene expression in rats with emphysema].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20020101

Title: Synthesis of cholecystokinin peptide CCK-4 exclusively by enzymatic methods.

Journal: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20020101

Title: [Characterization of cysteine proteinase endogenous inhibitors obtained from transformed fibroblasts].

Journal: Voprosy meditsinskoi khimii 20020101

Title: [Reactions of derivatives of beta-lactam antibiotics with non-antibacterial biological activity].

Journal: Acta pharmaceutica Hungarica 20020101

Title: Kinetics of modulation of tetrodotoxin-sensitive and tetrodotoxin-resistant sodium channels by tetramethrin and deltamethrin.

Journal: The Journal of pharmacology and experimental therapeutics 20011201

Title: Studies on the inactivation of soluble and immobilized papain by the ascorbic acid-Cu2+ system: a model to propose the effect of free radicals on membrane-bound enzymes in vivo.

Journal: Biotechnology and applied biochemistry 20011201

Title: Identification, characterization and localization of chagasin, a tight-binding cysteine protease inhibitor in Trypanosoma cruzi.

Journal: Journal of cell science 20011101

Title: Broad specificity alkaline proteases efficiently reduce the visual scaling associated with soap-induced xerosis.

Journal: Archives of dermatological research 20011101

Title: Electrostatic recognition between enzyme and inhibitor: interaction between papain and leupeptin.

Journal: Archives of biochemistry and biophysics 20011015

Title: Rapidly inactivating and non-inactivating calcium-activated potassium currents in frog saccular hair cells.

Journal: The Journal of physiology 20011001

Title: Domain-domain interactions of HtpG, an Escherichia coli homologue of eukaryotic HSP90 molecular chaperone.

Journal: European journal of biochemistry 20011001

Title: The N-terminal part of recombinant human tear lipocalin/von Ebner's gland protein confers cysteine proteinase inhibition depending on the presence of the entire cystatin-like sequence motifs.

Journal: Biological chemistry 20011001

Title: Cloning and expression of a novel hepatitis B virus-binding protein from HepG2 cells.

Journal: The Journal of biological chemistry 20010928

Title: Proteinase activity in the white shrimp (Penaeus vannamei) clotting protein.

Journal: Biochemical and biophysical research communications 20010921

Title: Vinyl sulfonium as novel proteolytic enzyme inhibitor.

Journal: Bioorganic & medicinal chemistry letters 20010903

Title: Lysosomal cysteine proteases: facts and opportunities.

Journal: The EMBO journal 20010903

Title: Interactions of human lacrimal and salivary cystatins with adenovirus endopeptidase.

Journal: Antiviral research 20010901

Title: Role of the single cysteine residue, Cys 3, of human and bovine cystatin B (stefin B) in the inhibition of cysteine proteinases.

Journal: Protein science : a publication of the Protein Society 20010901

Title: Channel cytoplasmic loops alter voltage-dependent sodium channel activation in an isoform-specific manner.

Journal: The Journal of physiology 20010901

Title: Phage display selection of hairpin loop soyacystatin variants that mediate high affinity inhibition of a cysteine proteinase.

Journal: The Plant journal : for cell and molecular biology 20010901

Title: The reaction of serpins with proteinases involves important enthalpy changes.

Journal: Biochemistry 20010821

Title: Discovery of a new inhibitor lead of adenovirus proteinase: steps toward selective, irreversible inhibitors of cysteine proteinases.

Journal: FEBS letters 20010803

Title: Box jellyfish (Carybdea alata) in Waikiki. The analgesic effect of sting-aid, Adolph's meat tenderizer and fresh water on their stings: a double-blinded, randomized, placebo-controlled clinical trial.

Journal: Hawaii medical journal 20010801

Title: Variation in aspects of cysteine proteinase catalytic mechanism deduced by spectroscopic observation of dithioester intermediates, kinetic analysis and molecular dynamics simulations.

Journal: The Biochemical journal 20010715

Title: Mixture of trypsin, chymotrypsin and papain reduces formation of metastases and extends survival time of C57Bl6 mice with syngeneic melanoma B16.

Journal: Cancer chemotherapy and pharmacology 20010701

Title: Retrolective cohort study of an additive therapy with an oral enzyme preparation in patients with multiple myeloma.

Journal: Cancer chemotherapy and pharmacology 20010701

Title: Structural characterization of pyrrolic cross-links in collagen using a biotinylated Ehrlich's reagent.

Journal: The Journal of biological chemistry 20010601

Title: Synthesis and hydrolysis by cysteine and serine proteases of short internally quenched fluorogenic peptides.

Journal: Analytical biochemistry 20010601

Title: Inhibition of cysteine protease activity by NO-donors.

Journal: Current protein & peptide science 20010601

Title: Recognition of IgG by Fcgamma receptor. The role of Fc glycosylation and the binding of peptide inhibitors.

Journal: The Journal of biological chemistry 20010511

Title: Synthesis and hydrolysis by cathepsin B of fluorogenic substrates with the general structure benzoyl-X-ARG-MCA containing non-natural basic amino acids at position X.

Journal: Biochimica et biophysica acta 20010505

Title: Counting the number of disulfides and thiol groups in proteins and a novel approach for determining the local pKa for cysteine groups in proteins in vivo.

Journal: Journal of synchrotron radiation 20010501

Title: Fragmentation of immunoglobulin G.

Journal: Current protocols in immunology 20010501

Title: The theory and application of transition state pK(a) values: the reaction of papain with a series of trimethylene disulphide reactivity probes.

Journal: Journal of theoretical biology 20010421

Title: Insight into the catalysis of hydrolysis of four newly synthesized substrates by papain: a proton inventory study.

Journal: Biochemistry 20010403

Title: Revisiting the enzymes stored in the laticifers of Carica papaya in the context of their possible participation in the plant defence mechanism.

Journal: Cellular and molecular life sciences : CMLS 20010401

Title: Molecular cloning and functional expression of cDNA encoding the cysteine proteinase inhibitor Sca from sunflower seeds.

Journal: Bioscience, biotechnology, and biochemistry 20010401

Title: Bm-CPI-2, a cystatin homolog secreted by the filarial parasite Brugia malayi, inhibits class II MHC-restricted antigen processing.

Journal: Current biology : CB 20010320

Title: Identification of internal autoproteolytic cleavage sites within the prosegments of recombinant procathepsin B and procathepsin S. Contribution of a plausible unimolecular autoproteolytic event for the processing of zymogens belonging to the papain family.

Journal: The Journal of biological chemistry 20010316

Title: Paramyxovirus fusion (F) protein: a conformational change on cleavage activation.

Journal: Virology 20010301

Title: S1 subsite specificity of a recombinant cysteine proteinase, CPB, of Leishmania mexicana compared with cruzain, human cathepsin L and papain using substrates containing non-natural basic amino acids.

Journal: European journal of biochemistry 20010301

Title: A constitutive cystatin-encoding gene from barley (Icy) responds differentially to abiotic stimuli.

Journal: Plant molecular biology 20010301

Title: A cystatin-based affinity procedure for the isolation and analysis of papain-like cysteine proteinases from tissue extracts.

Journal: Analytical biochemistry 20010215

Title: Papain immobilization on a nitrilon fibre carrier containing primary amine groups.

Journal: Biotechnology and applied biochemistry 20010201

Title: Interaction of cysteine proteases with calciotropic hormone receptors.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20010201

Title: Papain does not cleave operator-bound lambda repressor: structural characterization of the carboxy terminal domain and the hinge.

Journal: Journal of biomolecular structure & dynamics 20010201

Title: Complex effects of papain on function and inhibitor sensitivity of the red cell anion exchanger AE1 suggest the presence of different transport subsites.

Journal: The Journal of membrane biology 20010201

Title: High-level production of recombinant chicken cystatin by Pichia pastoris and its application in mackerel surimi.

Journal: Journal of agricultural and food chemistry 20010201

Title: Identification of a membrane-associated cysteine protease with possible dual roles in the endoplasmic reticulum and protein storage vacuole.

Journal: The Journal of biological chemistry 20010105

Title: Modification of cyclosporin A and conjugation of its derivative to HPMA copolymers.

Journal: Bioconjugate chemistry 20010101

Title: Protons inhibit the BK(Ca) channel of rat small artery smooth muscle cells.

Journal: Journal of vascular research 20010101

Title: [Anti-inflammatory activity of domestic papain].

Journal: Eksperimental'naia i klinicheskaia farmakologiia 20010101

Title: The combined treatment of transplantable solid mammary carcinoma in Wistar rats by use of photodynamic therapy and cysteine proteinase inhibitor.

Journal: In vivo (Athens, Greece) 20010101

Title: Immobilization of papain on cold-plasma functionalized polyethylene and glass surfaces.

Journal: Journal of biomaterials science. Polymer edition 20010101

Title: Excitability in chemical and biochemical pH-autocatalytic systems.

Journal: Faraday discussions 20010101

Title: Influence of organic solvents on papain kinetics.

Journal: Acta biochimica Polonica 20010101

Title: Influence of Me2SO and incubation time on papain activity studied using fluorogenic substrates.

Journal: Acta biochimica Polonica 20010101

Title: Synthesis of some pseudo-peptide analogs of thiol proteinase inhibitors.

Journal: Chemical & pharmaceutical bulletin 19990301

Title: Chromogenic and fluorogenic glycosylated and acetylglycosylated peptides as substrates for serine, thiol and aspartyl proteases.

Journal: The journal of peptide research : official journal of the American Peptide Society 19990201

Title: Domain structure and conformation of a cellobiohydrolase from Trichoderma pseudokiningii S-38.

Journal: Journal of protein chemistry 19970101

Title: Amino acids and peptides. XXVIII. Preparation of poly(ethylene glycol) hybrids of Gln-Val-Val-Ala-Gly analogs and their inhibitory effect on papain.

Journal: Biological & pharmaceutical bulletin 19960601

Title: Separation of functional domains for the alpha-1,4 and alpha-1,6 hydrolytic activities of a Bacillus amylopullulanase by limited proteolysis with papain.

Journal: Bioscience, biotechnology, and biochemistry 19960401

Title: Interaction of ebselen with glutathione S-transferase and papain in vitro.

Journal: Biochemical pharmacology 19940315

Title: Peptide production by a combination of gene expression, chemical synthesis, and protease-catalyzed conversion.

Journal: International journal of peptide and protein research 19930401

Title: Crystal structure of papain-succinyl-Gln-Val-Val-Ala-Ala-p-nitroanilide complex at 1.7-A resolution: noncovalent binding mode of a common sequence of endogenous thiol protease inhibitors.

Journal: Biochemistry 19921124

Title: Papain-inhibitory activity of oryzacystatin, a rice seed cysteine proteinase inhibitor, depends on the central Gln-Val-Val-Ala-Gly region conserved among cystatin superfamily members.

Journal: Journal of biochemistry 19910201

Title: An efficient chemical-enzymatic synthesis of LHRH N-terminal pentapeptide.

Journal: Biomedica biochimica acta 19910101

Title: A methodological study of the enzymatic synthesis of the tripeptide Z-Cys(Bzl)-Tyr-Ile-OtBu.

Journal: Peptide research 19910101

Title: The NH2-terminal 21 amino acid residues are not essential for the papain-inhibitory activity of oryzacystatin, a member of the cystatin superfamily. Expression of oryzacystatin cDNA and its truncated fragments in Escherichia coli.

Journal: The Journal of biological chemistry 19880605

Title: Amino acids and peptides. XX. Inhibition of papain by succinyl-Gln-Val-Val-Ala-Ala-p-nitroanilide, a common sequence of endogenous thiol proteinase inhibitors.

Journal: Chemical & pharmaceutical bulletin 19880601

Title: Significant effects of Z-Gln-Val-Val-OME, common sequences of thiol proteinase inhibitors on thiol proteinases.

Journal: Biochemical and biophysical research communications 19870313

Title: Structural studies and two-dimensional gel electrophoresis of gamma-glutamyl transpeptidase.

Journal: Archives of biochemistry and biophysics 19860515

Title: Carboxyl-modified amino acids and peptides as protease inhibitors.

Journal: Journal of medicinal chemistry 19860101

Title: Significant effects of synthetic Gln-Val-Val-Ala-Gly and its derivatives, common sequences of thiol proteinase inhibitors, on thiol proteinase.

Journal: Chemical & pharmaceutical bulletin 19851101

Title: Case report. Immunological studies in a case of hepatitis following methyldopa administration.

Journal: The American journal of the medical sciences 19790101

Title: The pKa value of the active site histidine in photo-oxidised papain.

Journal: FEBS letters 19760101

Title: The effect of acid treatment upon the susceptibility of rabbit IgG to proteolytic cleavage with various enzymes.

Journal: Immunochemistry 19750801

Title: Machado MN, et al. Bone Marrow-Derived Mononuclear Cell Therapy in Papain-Induced Experimental Pulmonary Emphysema. Front Physiol. 2018 Feb 20;9:121.

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Tags:9001-73-4 Molecular Formula|9001-73-4 MDL|9001-73-4 SMILES|9001-73-4 Papain