Title: Upregulation of histone-lysine methyltransferases plays a causal role in hexavalent chromium-induced cancer stem cell-like property and cell transformation.
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Title: Inhibition of euchromatic histone methyltransferase 1 and 2 sensitizes chronic myeloid leukemia cells to interferon treatment.
Journal: PloS one 20140101
Title: Identification of potent Yes1 kinase inhibitors using a library screening approach.
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Title: Inhibition of H3K9 methyltransferases G9a/GLP prevents ototoxicity and ongoing hair cell death.
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Title: Optimization of cellular activity of G9a inhibitors 7-aminoalkoxy-quinazolines.
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Title: Epigenetic regulation of HIV-1 transcription.
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Title: A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells.
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Title: Structural basis for G9a-like protein lysine methyltransferase inhibition by BIX-01294.
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Title: Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds.
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Title: Chemical probes for histone-modifying enzymes.
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Title: Reversal of H3K9me2 by a small-molecule inhibitor for the G9a histone methyltransferase.
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Journal: The Journal of biological chemistry 20020419
