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944328-88-5,MFCD18086864
Catalog No.:AA01DNN4

944328-88-5 | QS11 free

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$46.00   $32.00
- +
5mg
≥98%
in stock  
$199.00   $139.00
- +
10mg
≥98%
in stock  
$329.00   $230.00
- +
25mg
≥98%
in stock  
$762.00   $533.00
- +
50mg
≥98%
in stock  
$1,415.00   $990.00
- +
100mg
≥98%
in stock  
$2,390.00   $1,673.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA01DNN4
Chemical Name:
QS11 free
CAS Number:
944328-88-5
Molecular Formula:
C36H33N5O2
Molecular Weight:
567.6795
MDL Number:
MFCD18086864
SMILES:
OC[C@@H](Nc1nc(Oc2ccc3c(c2)CCC3)nc2c1ncn2Cc1ccc(cc1)c1ccccc1)Cc1ccccc1
Properties
Computed Properties
 
Complexity:
842  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
43  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
10  
XLogP3:
7.6  

Literature

Title: Identification of potent Yes1 kinase inhibitors using a library screening approach.

Journal: Bioorganic & medicinal chemistry letters 20130801

Title: Manish K. Singh, et al. Structure-activity Relationship Studies of QS11, a Small Molecule Wnt Synergistic Agonist. Bioorg Med Chem Lett. 2015 Nov 1; 25(21): 4838–4842.

Title: Zhang Q, et al. Small-molecule synergist of the Wnt/beta-catenin signaling pathway. Proc Natl Acad Sci U S A. 2007 May 1;104(18):7444-8.

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SDS
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