Title: Central IKK2 Inhibition Ameliorates Air Pollution-Mediated Hepatic Glucose and Lipid Metabolism Dysfunction in Mice With Type II Diabetes.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20180701
Title: Identification of potent Yes1 kinase inhibitors using a library screening approach.
Journal: Bioorganic & medicinal chemistry letters 20130801
Title: Structure-activity relationships of antitubercular salicylanilides consistent with disruption of the proton gradient via proton shuttling.
Journal: Bioorganic & medicinal chemistry 20130101
Title: Salicylanilide inhibitors of Toxoplasma gondii.
Journal: Journal of medicinal chemistry 20121011
Title: Activation of nuclear factor-κB pathway is responsible for tumor necrosis factor-α-induced up-regulation of endothelin B2 receptor expression in vascular smooth muscle cells in vitro.
Journal: Toxicology letters 20120307
Title: An IκB kinase 2 inhibitor IMD-0354 suppresses the survival of adult T-cell leukemia cells.
Journal: Cancer science 20120101
Title: Regulation of cytochrome P450 4F11 by nuclear transcription factor-κB.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20120101
Title: A novel IKK inhibitor prevents progression of restenosis after arterial injury in mice.
Journal: International heart journal 20120101
Title: Amelioration of endotoxin-induced uveitis treated with an IκB kinase β inhibitor in rats.
Journal: Molecular vision 20120101
Title: IκB kinase-beta inhibitor attenuates hepatic fibrosis in mice.
Journal: World journal of gastroenterology 20111221
Title: IκB kinase β inhibitor IMD-0354 suppresses airway remodelling in a Dermatophagoides pteronyssinus-sensitized mouse model of chronic asthma.
Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20110101
Title: Poly(I:C) reduces expression of JAM-A and induces secretion of IL-8 and TNF-α via distinct NF-κB pathways in human nasal epithelial cells.
Journal: Toxicology and applied pharmacology 20110101
Title: A novel NF-κB inhibitor improves glucocorticoid sensitivity of canine neoplastic lymphoid cells by up-regulating expression of glucocorticoid receptors.
Journal: Research in veterinary science 20101201
Title: Copper activation of NF-kappaB signaling in HepG2 cells.
Journal: Journal of molecular biology 20091113
Title: Activation of host antiviral RNA-sensing factors necessary for herpes simplex virus type 1-activated transcription of host cell fucosyltransferase genes FUT3, FUT5, and FUT6 and subsequent expression of sLe(x) in virus-infected cells.
Journal: Glycobiology 20090701
Title: Antiallergic and anti-inflammatory effects of a novel I kappaB kinase beta inhibitor, IMD-0354, in a mouse model of allergic inflammation.
Journal: International archives of allergy and immunology 20090101
Title: NF-kappaB-mediated HER2 overexpression in radiation-adaptive resistance.
Journal: Radiation research 20090101
Title: Effectiveness of IkappaB kinase inhibitors in murine colitis-associated tumorigenesis.
Journal: Journal of gastroenterology 20090101
Title: Lipid-soluble smoke particles upregulate vascular smooth muscle ETB receptors via activation of mitogen-activating protein kinases and NF-kappaB pathways.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20081201
Title: Mechanism of signal transduction in tumor necrosis factor-like weak inducer of apoptosis-induced matrix degradation by MMP-3 upregulation in disc tissues.
Journal: Spine 20081101
Title: Inhibition of IkappaB kinase beta restrains oncogenic proliferation of pancreatic cancer cells.
Journal: Journal of medical and dental sciences 20080301
Title: Simvastatin inhibits TNFalpha-induced invasion of human cardiac myofibroblasts via both MMP-9-dependent and -independent mechanisms.
Journal: Journal of molecular and cellular cardiology 20070801
Title: Topical application with a new NF-kappaB inhibitor improves atopic dermatitis in NC/NgaTnd mice.
Journal: The Journal of investigative dermatology 20070401
Title: Inhibition of NF-{kappa}B improves left ventricular remodeling and cardiac dysfunction after myocardial infarction.
Journal: American journal of physiology. Heart and circulatory physiology 20070101
Title: Thymic stromal lymphopoietin secretion of synovial fibroblasts is positively and negatively regulated by Toll-like receptors/nuclear factor-kappaB pathway and interferon-gamma/dexamethasone.
Journal: Modern rheumatology 20070101
Title: A novel IkappaB kinase-beta inhibitor ameliorates bleomycin-induced pulmonary fibrosis in mice.
Journal: American journal of respiratory and critical care medicine 20060501
Title: A new IkappaB kinase beta inhibitor prevents human breast cancer progression through negative regulation of cell cycle transition.
Journal: Cancer research 20060101
Title: A novel NF-kappaB inhibitor, IMD-0354, suppresses neoplastic proliferation of human mast cells with constitutively activated c-kit receptors.
Journal: Blood 20050315
Title: A novel IKKbeta inhibitor stimulates adiponectin levels and ameliorates obesity-linked insulin resistance.
Journal: Biochemical and biophysical research communications 20041008
Title: Inhibition of the activation of nuclear factor kappa B to reduce myocardial reperfusion injury and infarct size.
Journal: Cardiovascular research 20040701
Title: Inhibition of IkappaB phosphorylation in cardiomyocytes attenuates myocardial ischemia/reperfusion injury.
Journal: Cardiovascular research 20040701
Title: Tanaka A, et al. A novel NF-kappaB inhibitor, IMD-0354, suppresses neoplastic proliferation of human mast cells with constitutively activated c-kit receptors. Blood. 2005 Mar 15;105(6):2324-31.
Title: Li YR, et al. Study of the inhibitory effects on TNF-α-induced NF-κB activation of IMD0354 analogs. Chem Biol Drug Des. 2017 Dec;90(6):1307-1311.
Title: Tanaka A, et al. A new IkappaB kinase beta inhibitor prevents human breast cancer progression through negative regulation of cell cycle transition. Cancer Res. 2006 Jan 1;66(1):419-26.
Title: Lennikov A, et al. Amelioration of endotoxin-induced uveitis treated with an IκB kinase β inhibitor in rats. Mol Vis. 2012;18:2586-97.
