Home Amines 179248-59-0
179248-59-0,MFCD01815300
Catalog No.:AA0026SM

179248-59-0 | 4-Quinazolinamine, 6,7-dimethoxy-N-(4-phenoxyphenyl)-

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
99%
in stock  
$12.00   $8.00
- +
5mg
99%
in stock  
$26.00   $18.00
- +
10mg
99%
in stock  
$34.00   $24.00
- +
25mg
99%
in stock  
$42.00   $29.00
- +
50mg
99%
in stock  
$53.00   $37.00
- +
100mg
99%
in stock  
$68.00   $48.00
- +
250mg
99%
in stock  
$101.00   $71.00
- +
1g
99%
in stock  
$246.00   $172.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0026SM
Chemical Name:
4-Quinazolinamine, 6,7-dimethoxy-N-(4-phenoxyphenyl)-
CAS Number:
179248-59-0
Molecular Formula:
C22H19N3O3
Molecular Weight:
373.4046
MDL Number:
MFCD01815300
SMILES:
COc1cc2c(ncnc2cc1OC)Nc1ccc(cc1)Oc1ccccc1
Properties
Properties
 
Form:
Solid  
Solubility:
DMSO: >10mg/mL  
Storage:
Keep in dry area;2-8℃;  

Computed Properties
 
Complexity:
466  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
28  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
6  
XLogP3:
4.9  

Literature

Title: A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery.

Journal: The Biochemical journal 20130415

Title: Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity.

Journal: Nature biotechnology 20111101

Title: Protein kinase G type Ialpha activity in human ovarian cancer cells significantly contributes to enhanced Src activation and DNA synthesis/cell proliferation.

Journal: Molecular cancer research : MCR 20100401

Title: The selectivity of protein kinase inhibitors: a further update.

Journal: The Biochemical journal 20071215

Title: Frontal affinity chromatography with MS detection of EphB2 tyrosine kinase receptor. 2. Identification of small-molecule inhibitors via coupling with virtual screening.

Journal: Journal of medicinal chemistry 20050505

Title: Frontal affinity chromatography with MS detection of EphB2 tyrosine kinase receptor. 1. Comparison with conventional ELISA.

Journal: Journal of medicinal chemistry 20041007

Title: Structural determinants for potent, selective dual site inhibition of human pp60c-src by 4-anilinoquinazolines.

Journal: Biochemistry 20010619

Title: Tian G, et al. Structural determinants for potent, selective dual site inhibition of human pp60c-src by 4-anilinoquinazolines. Biochemistry. 2001 Jun 19;40(24):7084-91.

Title: Bain J, et al. The selectivity of protein kinase inhibitors: a further update. Biochem J. 2007 Dec 15;408(3):297-315.

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SDS
Tags:179248-59-0 Molecular Formula|179248-59-0 MDL|179248-59-0 SMILES|179248-59-0 4-Quinazolinamine, 6,7-dimethoxy-N-(4-phenoxyphenyl)-