Home Amines 153436-53-4
153436-53-4,MFCD00270914
Catalog No.:AA0020AV

153436-53-4 | N-(3-chlorophenyl)-6,7-dimethoxyquinazolin-4-amine

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1mg
≥98%
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$32.00   $22.00
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5mg
≥98%
in stock  
$136.00   $95.00
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10mg
≥98%
in stock  
$193.00   $135.00
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25mg
≥98%
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$365.00   $255.00
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50mg
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$543.00   $380.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA0020AV
Chemical Name:
N-(3-chlorophenyl)-6,7-dimethoxyquinazolin-4-amine
CAS Number:
153436-53-4
Molecular Formula:
C16H14ClN3O2
Molecular Weight:
315.7543
MDL Number:
MFCD00270914
SMILES:
COc1cc2c(ncnc2cc1OC)Nc1cccc(c1)Cl
NSC Number:
693255
Properties
Computed Properties
 
Complexity:
360  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
22  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
4  
XLogP3:
4  

Downstream Synthesis Route

[1]Hu,Shaojing;Xie,Guojian;Zhang,DonX.;Davis,Charles;Long,Wei;Hu,Yunyan;Wang,Fei;Kang,Xinshan;Tan,Fenlai;Ding,Lieming;Wang,Yinxiang[BioorganicandMedicinalChemistryLetters,2012,vol.22,#19,p.6301-6305]

[1]Hu,Shaojing;Xie,Guojian;Zhang,DonX.;Davis,Charles;Long,Wei;Hu,Yunyan;Wang,Fei;Kang,Xinshan;Tan,Fenlai;Ding,Lieming;Wang,Yinxiang[BioorganicandMedicinalChemistryLetters,2012,vol.22,#19,p.6301-6305]

[1]Jain,KishoreS.;Kathiravan,MuthuK.;Bariwal,JitenderB.;Chaskar,PratipK.;Tompe,SantoshS.;Arya,Nikhilesh[SyntheticCommunications,2013,vol.43,#5,p.719-727]

[1]Jain,KishoreS.;Kathiravan,MuthuK.;Bariwal,JitenderB.;Chaskar,PratipK.;Tompe,SantoshS.;Arya,Nikhilesh[SyntheticCommunications,2013,vol.43,#5,p.719-727]

Literature

Title: Bojko A, et al. The effect of tyrphostins AG494 and AG1478 on the autocrine growth regulation of A549 and DU145 cells. Folia Histochem Cytobiol. 2012 Jul 5;50(2):186-95.

Title: Li W, et al. EGFR Inhibition Blocks Palmitic Acid-induced inflammation in cardiomyocytes and Prevents Hyperlipidemia-induced Cardiac Injury in Mice. Sci Rep. 2016 Apr 18;6:24580.

Title: Akhtar S, et al. Cationic Polyamidoamine Dendrimers as Modulators of EGFR Signaling In Vitro and In Vivo. PLoS One. 2015 Jul 13;10(7):e0132215.

Title: Dorobantu CM, et al. Tyrphostin AG1478 Inhibits Encephalomyocarditis Virus and Hepatitis C Virus by Targeting Phosphatidylinositol 4-Kinase IIIα. Antimicrob Agents Chemother. 2016 Sep 23;60(10):6402-6.

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SDS
Tags:153436-53-4 Molecular Formula|153436-53-4 MDL|153436-53-4 SMILES|153436-53-4 N-(3-chlorophenyl)-6,7-dimethoxyquinazolin-4-amine