[1]CollectionofCzechoslovakChemicalCommunications,2007,vol.72,p.1319-1330
[2]BioorganicandMedicinalChemistryLetters,2014,vol.24,p.3480-3485
[3]JournalofOrganicChemistry,1957,vol.22,p.1380,1383
[1]JournaloftheChemicalSociety.PerkintransactionsI,1972,vol.19,p.2423-2425
Title: Upregulation of hydroxysteroid sulfotransferase 2B1b promotes hepatic oval cell proliferation by modulating oxysterol-induced LXR activation in a mouse model of liver injury.
Journal: Archives of toxicology 20170101
Title: Quercetin-3-O-(2″-galloyl)-α-L-rhamnopyranoside attenuates cholesterol oxidation product-induced apoptosis by suppressing NF-κB-mediated cell death process in differentiated PC12 cells.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20150801
Title: Antimycobacterial and photosynthetic electron transport inhibiting activity of ring-substituted 4-arylamino-7-chloroquinolinium chlorides.
Journal: Molecules (Basel, Switzerland) 20130902
Title: Interferon-inducible cholesterol-25-hydroxylase broadly inhibits viral entry by production of 25-hydroxycholesterol.
Journal: Immunity 20130124
Title: 3D models of human ERα and ERβ complexed with 5-androsten-3β,17β-diol.
Journal: Steroids 20121001
Title: High sensitivity measurements of active oxysterols with automated filtration/filter backflush-solid phase extraction-liquid chromatography-mass spectrometry.
Journal: Journal of chromatography. A 20120914
Title: Flip-flop of steroids in phospholipid bilayers: effects of the chemical structure on transbilayer diffusion.
Journal: Journal of the American Chemical Society 20120725
Title: Highly potent binding and inverse agonist activity of bisphenol A derivatives for retinoid-related orphan nuclear receptor RORγ.
Journal: Toxicology letters 20120720
Title: Oxysterols exert proinflammatory effects in placental trophoblasts via TLR4-dependent, cholesterol-sensitive activation of NF-κB.
Journal: Molecular human reproduction 20120701
Title: Oxysterol sulfation by cytosolic sulfotransferase suppresses liver X receptor/sterol regulatory element binding protein-1c signaling pathway and reduces serum and hepatic lipids in mouse models of nonalcoholic fatty liver disease.
Journal: Metabolism: clinical and experimental 20120601
Title: Regulation of the expression of interleukin-8 induced by 25-hydroxycholesterol in retinal pigment epithelium cells.
Journal: Acta ophthalmologica 20120601
Title: Antisteroidogenic effects of hydrogen peroxide on rat granulosa cells.
Journal: Free radical research 20120601
Title: Effect of triptolide on progesterone production from cultured rat granulosa cells.
Journal: Arzneimittel-Forschung 20120601
Title: 25-Hydroxycholesterol-3-sulfate attenuates inflammatory response via PPARγ signaling in human THP-1 macrophages.
Journal: American journal of physiology. Endocrinology and metabolism 20120401
Title: Increased 25-hydroxycholesterol concentrations in the lungs of patients with chronic obstructive pulmonary disease.
Journal: Respirology (Carlton, Vic.) 20120401
Title: Inhibition of cholesterol oxidation products (COPs) formation in emulsified porcine patties by phenolic-rich avocado (Persea americana Mill.) extracts.
Journal: Journal of agricultural and food chemistry 20120307
Title: Comparative modeling of 25-hydroxycholesterol-7α-hydroxylase (CYP7B1): ligand binding and analysis of hereditary spastic paraplegia type 5 CYP7B1 mutations.
Journal: Journal of molecular modeling 20120201
Title: Resveratrol increases the expression and activity of the low density lipoprotein receptor in hepatocytes by the proteolytic activation of the sterol regulatory element-binding proteins.
Journal: Atherosclerosis 20120201
Title: HCV NS5A and NS5B enhance expression of human ceramide glucosyltransferase gene.
Journal: Virologica Sinica 20120201
Title: Interferon regulator factor 1/retinoic inducible gene I (IRF1/RIG-I) axis mediates 25-hydroxycholesterol-induced interleukin-8 production in atherosclerosis.
Journal: Cardiovascular research 20120101
Title: Steroidogenesis in amlodipine treated purified Leydig cells.
Journal: Toxicology and applied pharmacology 20120101
Title: Inhibition of endothelial- and neuronal-type, but not inducible-type, nitric oxide synthase by the oxidized cholesterol metabolite secosterol aldehyde: Implications for vascular and neurodegenerative diseases.
Journal: Journal of clinical biochemistry and nutrition 20120101
Title: TGFβ signaling and cardiovascular diseases.
Journal: International journal of biological sciences 20120101
Title: Activation mobilizes the cholesterol in the late endosomes-lysosomes of Niemann Pick type C cells.
Journal: PloS one 20120101
Title: Strain specific transcriptional response in Mycobacterium tuberculosis infected macrophages.
Journal: Cell communication and signaling : CCS 20120101
Title: Progesterone synthesis in the nervous system: implications for myelination and myelin repair.
Journal: Frontiers in neuroscience 20120101
Title: Central role of SREBP-2 in the pathogenesis of osteoarthritis.
Journal: PloS one 20120101
Title: VEGF is involved in the increase of dermal microvascular permeability induced by tryptase.
Journal: ISRN dermatology 20120101
Title: 25-Hydroxycholesterol enhances cytokine release and Toll-like receptor 3 response in airway epithelial cells.
Journal: Respiratory research 20120101
Title: The ATP-binding cassette transporter-2 (ABCA2) regulates cholesterol homeostasis and low-density lipoprotein receptor metabolism in N2a neuroblastoma cells.
Journal: Biochimica et biophysica acta 20111201
Title: Linalool reduces the expression of 3-hydroxy-3-methylglutaryl CoA reductase via sterol regulatory element binding protein-2- and ubiquitin-dependent mechanisms.
Journal: FEBS letters 20111020
Title: OSBP-related protein 7 interacts with GATE-16 and negatively regulates GS28 protein stability.
Journal: Experimental cell research 20111001
Title: Natural products reveal cancer cell dependence on oxysterol-binding proteins.
Journal: Nature chemical biology 20110807
Title: Cholesterol 25-hydroxylation activity of CYP3A.
Journal: Journal of lipid research 20110801
Title: Still another activity by the highly promiscuous enzyme CYP3A4: 25-hydroxylation of cholesterol.
Journal: Journal of lipid research 20110801
Title: Oxysterols direct B-cell migration through EBI2.
Journal: Nature 20110727
Title: Synthesis and evaluation of diarylthiazole derivatives that inhibit activation of sterol regulatory element-binding proteins.
Journal: Journal of medicinal chemistry 20110714
Title: Effect of high pressure processing on cholesterol oxidation products in vacuum packaged sliced dry-cured ham.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110601
Title: Membrane-associated ubiquitin ligase complex containing gp78 mediates sterol-accelerated degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
Journal: The Journal of biological chemistry 20110429
Title: Lycopene prevention of oxysterol-induced proinflammatory cytokine cascade in human macrophages: inhibition of NF-κB nuclear binding and increase in PPARγ expression.
Journal: The Journal of nutritional biochemistry 20110301
Title: 25-Hydroxycholesterol increases the availability of cholesterol in phospholipid membranes.
Journal: Biophysical journal 20110216
Title: Sulfation of 25-hydroxycholesterol by SULT2B1b decreases cellular lipids via the LXR/SREBP-1c signaling pathway in human aortic endothelial cells.
Journal: Atherosclerosis 20110201
Title: Oxysterols inhibit differentiation and fusion of term primary trophoblasts by activating liver X receptors.
Journal: Placenta 20110201
Title: (Sub)clinical cardiovascular disease is associated with increased bone loss and fracture risk; a systematic review of the association between cardiovascular disease and osteoporosis.
Journal: Arthritis research & therapy 20110101
Title: The cholesterol metabolite 25-hydroxycholesterol activates estrogen receptor α-mediated signaling in cancer cells and in cardiomyocytes.
Journal: PloS one 20110101
Title: Functional promoter polymorphisms govern differential expression of HMG-CoA reductase gene in mouse models of essential hypertension.
Journal: PloS one 20110101
Title: Effects of the methanol extract of Basella alba L (Basellaceae) on steroid production in Leydig cells.
Journal: International journal of molecular sciences 20110101
Title: Mechanisms of oxysterol-induced carcinogenesis.
Journal: Lipids in health and disease 20110101
Title: Apelin attenuates the osteoblastic differentiation of vascular smooth muscle cells.
Journal: PloS one 20110101
Title: Synthesis of the enantiomer of the oxysterol-antagonist LY295427.
Journal: Steroids 20110101
Title: Coordinately regulated alternative splicing of genes involved in cholesterol biosynthesis and uptake.
Journal: PloS one 20110101
Title: Contribution of cholesterol and oxysterols in the physiopathology of cataract: implication for the development of pharmacological treatments.
Journal: Journal of ophthalmology 20110101
Title: OSBP-related protein 8 (ORP8) regulates plasma and liver tissue lipid levels and interacts with the nucleoporin Nup62.
Journal: PloS one 20110101
Title: Antiviral drugs against hepatitis C virus.
Journal: Genetic vaccines and therapy 20110101
Title: Comparative structural analysis of lipid binding START domains.
Journal: PloS one 20110101
Title: Lipids, lipoproteins, and age-related macular degeneration.
Journal: Journal of lipids 20110101
Title: Cholesterol-enriched diet causes age-related macular degeneration-like pathology in rabbit retina.
Journal: BMC ophthalmology 20110101
Title: Hepatic n-3 polyunsaturated fatty acid depletion promotes steatosis and insulin resistance in mice: genomic analysis of cellular targets.
Journal: PloS one 20110101
Title: Advanced glycation in macrophages induces intracellular accumulation of 7-ketocholesterol and total sterols by decreasing the expression of ABCA-1 and ABCG-1.
Journal: Lipids in health and disease 20110101
Title: Sphingomyelin synthases regulate protein trafficking and secretion.
Journal: PloS one 20110101
Title: A common polymorphism in NR1H2 (LXRbeta) is associated with preeclampsia.
Journal: BMC medical genetics 20110101
Title: Camphene, a plant-derived monoterpene, reduces plasma cholesterol and triglycerides in hyperlipidemic rats independently of HMG-CoA reductase activity.
Journal: PloS one 20110101
Title: Uropathogenic E. coli induce different immune response in testicular and peritoneal macrophages: implications for testicular immune privilege.
Journal: PloS one 20110101
Title: Nifedipine protects INS-1 β-cell from high glucose-induced ER stress and apoptosis.
Journal: International journal of molecular sciences 20110101
Title: The dynamin chemical inhibitor dynasore impairs cholesterol trafficking and sterol-sensitive genes transcription in human HeLa cells and macrophages.
Journal: PloS one 20110101
Title: Inflammatory-induced hibernation in the fetus: priming of fetal sheep metabolism correlates with developmental brain injury.
Journal: PloS one 20110101
Title: Activation of LDL receptor expression by small RNAs complementary to a noncoding transcript that overlaps the LDLR promoter.
Journal: Chemistry & biology 20101222
Title: Effects and mechanisms of nonylphenol on corticosterone release in rat zona fasciculata-reticularis cells.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20101201
Title: Identification of 5α, 6α-epoxycholesterol as a novel modulator of liver X receptor activity.
Journal: Molecular pharmacology 20101201
Title: Editorial: 25-Hydroxycholesterol: a new life in immunology.
Journal: Journal of leukocyte biology 20101201
Title: Molecular regulation of gonadotropin receptor expression: relationship to sterol metabolism.
Journal: Molecular and cellular endocrinology 20101125
Title: Lipid rafts and redox regulation of cellular signaling in cholesterol induced atherosclerosis.
Journal: Current cardiology reviews 20101101
Title: Effects of oxysterols on cell viability, inflammatory cytokines, VEGF, and reactive oxygen species production on human retinal cells: cytoprotective effects and prevention of VEGF secretion by resveratrol.
Journal: European journal of nutrition 20101001
Title: Modulators of the hedgehog signaling pathway.
Journal: Bioorganic & medicinal chemistry 20100915
Title: Placental ABCA1 and ABCG1 transporters efflux cholesterol and protect trophoblasts from oxysterol induced toxicity.
Journal: Biochimica et biophysica acta 20100901
Title: Regulation of hepatocyte lipid metabolism and inflammatory response by 25-hydroxycholesterol and 25-hydroxycholesterol-3-sulfate.
Journal: Lipids 20100901
Title: A second class of nuclear receptors for oxysterols: Regulation of RORalpha and RORgamma activity by 24S-hydroxycholesterol (cerebrosterol).
Journal: Biochimica et biophysica acta 20100801
Title: Multivesicular body formation requires OSBP-related proteins and cholesterol.
Journal: PLoS genetics 20100801
Title: Taking another look with fluorescence microscopy: image processing techniques in Langmuir monolayers for the twenty-first century.
Journal: Biochimica et biophysica acta 20100701
Title: Overexpression of STARD3 in human monocyte/macrophages induces an anti-atherogenic lipid phenotype.
Journal: Clinical science (London, England : 1979) 20100622
Title: Sterol-induced dislocation of 3-hydroxy-3-methylglutaryl coenzyme A reductase from endoplasmic reticulum membranes into the cytosol through a subcellular compartment resembling lipid droplets.
Journal: The Journal of biological chemistry 20100618
Title: Role of 8-iso-prostaglandin F2alpha and 25-hydroxycholesterol in the pathophysiology of endometriosis.
Journal: Fertility and sterility 20100601
Title: Interaction of two oxysterols, 7-ketocholesterol and 25-hydroxycholesterol, with phosphatidylcholine and sphingomyelin in model membranes.
Journal: Chemistry and physics of lipids 20100601
Title: Lipids-induced apoptosis is aggravated by acyl-coenzyme A: cholesterol acyltransferase inhibitor.
Journal: Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih 20100601
Title: Analysis of the 22-NBD-cholesterol transfer between liposome membranes and its relation to the intermembrane exchange of 25-hydroxycholesterol.
Journal: Colloids and surfaces. B, Biointerfaces 20100501
Title: Structural basis for hydroxycholesterols as natural ligands of orphan nuclear receptor RORgamma.
Journal: Molecular endocrinology (Baltimore, Md.) 20100501
Title: Electrostatic interaction between oxysterol-binding protein and VAMP-associated protein A revealed by NMR and mutagenesis studies.
Journal: The Journal of biological chemistry 20100423
Title: Marked accumulation of 27-hydroxycholesterol in SPG5 patients with hereditary spastic paresis.
Journal: Journal of lipid research 20100401
Title: Low-density lipoprotein and oxysterols suppress the transcription of CTP: Phosphoethanolamine cytidylyltransferase in vitro.
Journal: Biochimica et biophysica acta 20100401
Title: Regulation of hepatic gene expression by saturated fatty acids.
Journal: Prostaglandins, leukotrienes, and essential fatty acids 20100401
Title: Oxysterol represses high-affinity IgE receptor-stimulated mast cell activation in Liver X receptor-dependent and -independent manners.
Journal: FEBS letters 20100319
Title: Initial response of endothelial cells to acute stimulation with a lipid component: increase cyclooxygenase activity by induction of COX-2 through activation of tyrosine kinase.
Journal: Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20100201
Title: Intramembrane glycine mediates multimerization of Insig-2, a requirement for sterol regulation in Chinese hamster ovary cells.
Journal: Journal of lipid research 20100101
Title: Inhibition of carboxylesterase activity of THP1 monocytes/macrophages and recombinant human carboxylesterase 1 by oxysterols and fatty acids.
Journal: Biochimica et biophysica acta 20100101
Title: Perfusion of veins at arterial pressure increases the expression of KLF5 and cell cycle genes in smooth muscle cells.
Journal: Biochemical and biophysical research communications 20100101
Title: Metabolomic analyses of plasma reveals new insights into asphyxia and resuscitation in pigs.
Journal: PloS one 20100101
Title: Alterations in the homeostasis of phospholipids and cholesterol by antitumor alkylphospholipids.
Journal: Lipids in health and disease 20100101
Title: Oxpholipin 11D: an anti-inflammatory peptide that binds cholesterol and oxidized phospholipids.
Journal: PloS one 20100101
Title: Cellular cholesterol delivery, intracellular processing and utilization for biosynthesis of steroid hormones.
Journal: Nutrition & metabolism 20100101
Title: Effects of cholesterol and its 24S-OH and 25-OH oxysterols on choline acetyltransferase-positive neurons in brain slices.
Journal: Pharmacology 20100101
Title: Fathead minnow steroidogenesis: in silico analyses reveals tradeoffs between nominal target efficacy and robustness to cross-talk.
Journal: BMC systems biology 20100101
Title: Inhibition of stearoylCoA desaturase activity blocks cell cycle progression and induces programmed cell death in lung cancer cells.
Journal: PloS one 20100101
Title: Fish oil supplementation reverses the effect of cholesterol on apoptotic gene expression in smooth muscle cells.
Journal: Lipids in health and disease 20100101
Title: The oxysterol 27-hydroxycholesterol increases β-amyloid and oxidative stress in retinal pigment epithelial cells.
Journal: BMC ophthalmology 20100101
Title: Cholesterol pathways affected by small molecules that decrease sterol levels in Niemann-Pick type C mutant cells.
Journal: PloS one 20100101
Title: 5-Androstene-3β,7β,17β-triol (β-AET) slows thermal injury induced osteopenia in mice: relation to aging and osteoporosis.
Journal: PloS one 20100101
Title: 25-Hydroxycholesterol exerts both a cox-2-dependent transient proliferative effect and cox-2-independent cytotoxic effect on bovine endothelial cells in a time- and cell-type-dependent manner.
Journal: Journal of angiogenesis research 20100101
Title: Sitosterol reduces messenger RNA and protein expression levels of Niemann-Pick C1-like 1 in FHs 74 Int cells.
Journal: Nutrition research (New York, N.Y.) 20091201
Title: Insulin-like growth factor-I-stimulated Akt phosphorylation and oligodendrocyte progenitor cell survival require cholesterol-enriched membranes.
Journal: Journal of neuroscience research 20091115
Title: Apolipoprotein E on hepatitis C virion facilitates infection through interaction with low-density lipoprotein receptor.
Journal: Virology 20091110
Title: LXR-activating oxysterols induce the expression of inflammatory markers in endothelial cells through LXR-independent mechanisms.
Journal: Atherosclerosis 20091101
Title: Marked upregulation of cholesterol 25-hydroxylase expression by lipopolysaccharide.
Journal: Journal of lipid research 20091101
Title: Liver X receptor regulates expression of MRP2 but not that of MDR1 and BCRP in the liver.
Journal: Biochimica et biophysica acta 20091101
Title: Hepatocyte nuclear factor 1alpha plays a critical role in PCSK9 gene transcription and regulation by the natural hypocholesterolemic compound berberine.
Journal: The Journal of biological chemistry 20091016
Title: Regulation of inhibin/activin expression in rat early antral follicles.
Journal: Molecular and cellular endocrinology 20091015
Title: Effects of evodiamine and rutaecarpine on the secretion of corticosterone by zona fasciculata-reticularis cells in male rats.
Journal: Journal of cellular biochemistry 20091001
Title: Oncogenic Ras, but not (V600E)B-RAF, protects from cholesterol depletion-induced apoptosis through the PI3K/AKT pathway in colorectal cancer cells.
Journal: Carcinogenesis 20091001
Title: Oxysterol-induced rearrangement of the liquid-ordered phase: a possible link to Alzheimer's disease?
Journal: Journal of the American Chemical Society 20090902
Title: Effects of cholesterol and nuclear hormone receptor agonists on the production of transforming growth factor-beta in macrophages.
Journal: Bulletin of experimental biology and medicine 20090901
Title: Regulation of sterol regulatory element-binding transcription factor 1a by human chorionic gonadotropin and insulin in cultured rat theca-interstitial cells.
Journal: Biology of reproduction 20090801
Title: OSBPL10, a novel candidate gene for high triglyceride trait in dyslipidemic Finnish subjects, regulates cellular lipid metabolism.
Journal: Journal of molecular medicine (Berlin, Germany) 20090801
Title: OSBP-related protein 2 is a sterol receptor on lipid droplets that regulates the metabolism of neutral lipids.
Journal: Journal of lipid research 20090701
Title: Stimulation of Akt poly-ubiquitination and proteasomal degradation in P388D1 cells by 7-ketocholesterol and 25-hydroxycholesterol.
Journal: Archives of biochemistry and biophysics 20090701
Title: Ligand, receptor, and cell type-dependent regulation of ABCA1 and ABCG1 mRNA in prostate cancer epithelial cells.
Journal: Molecular cancer therapeutics 20090701
Title: Structure of N-terminal domain of NPC1 reveals distinct subdomains for binding and transfer of cholesterol.
Journal: Cell 20090626
Title: FGF-1 induces expression of LXRalpha and production of 25-hydroxycholesterol to upregulate the apoE gene in rat astrocytes.
Journal: Journal of lipid research 20090601
Title: Desmosterol can replace cholesterol in sustaining cell proliferation and regulating the SREBP pathway in a sterol-Delta24-reductase-deficient cell line.
Journal: The Biochemical journal 20090513
Title: 25-hydroxycholesterol provokes oligodendrocyte cell line apoptosis and stimulates the secreted phospholipase A2 type IIA via LXR beta and PXR.
Journal: Journal of neurochemistry 20090501
Title: Perturbations of membrane structure by cholesterol and cholesterol derivatives are determined by sterol orientation.
Journal: Journal of the American Chemical Society 20090408
Title: 7beta-Hydroxycholesterol and 25-hydroxycholesterol-induced interleukin-8 secretion involves a calcium-dependent activation of c-fos via the ERK1/2 signaling pathway in THP-1 cells: oxysterols-induced IL-8 secretion is calcium-dependent.
Journal: Cell biology and toxicology 20090401
Title: Relationship of metabolic syndrome with incident aortic valve calcium and aortic valve calcium progression: the Multi-Ethnic Study of Atherosclerosis (MESA).
Journal: Diabetes 20090401
Title: Regulation of the proprotein convertase subtilisin/kexin type 9 in intestinal epithelial cells.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20090401
Title: Direct effects, compensation, and recovery in female fathead minnows exposed to a model aromatase inhibitor.
Journal: Environmental health perspectives 20090401
Title: Cholesterol-dependent anaplasma phagocytophilum exploits the low-density lipoprotein uptake pathway.
Journal: PLoS pathogens 20090301
Title: Highly sensitive quantification of key regulatory oxysterols in biological samples by LC-ESI-MS/MS.
Journal: Journal of lipid research 20090201
Title: Activation of hepatic lipase expression by oleic acid: possible involvement of USF1.
Journal: Nutrients 20090201
Title: Side chain oxygenated cholesterol regulates cellular cholesterol homeostasis through direct sterol-membrane interactions.
Journal: The Journal of biological chemistry 20090116
Title: Characterization of fluorescent sterol binding to purified human NPC1.
Journal: The Journal of biological chemistry 20090116
Title: A facile synthesis of C-24 and C-25 oxysterols by in situ generated ethyl(trifluoromethyl)dioxirane.
Journal: Steroids 20090101
Title: Transcriptional profiling of the effects of 25-hydroxycholesterol on human hepatocyte metabolism and the antiviral state it conveys against the hepatitis C virus.
Journal: BMC chemical biology 20090101
Title: Sequential metabolism of 7-dehydrocholesterol to steroidal 5,7-dienes in adrenal glands and its biological implication in the skin.
Journal: PloS one 20090101
Title: Identification of novel genes and pathways regulating SREBP transcriptional activity.
Journal: PloS one 20090101
Title: [Activation of sterol regulatory element binding protein and its involvement in endothelial cell migration].
Journal: Zhonghua bing li xue za zhi = Chinese journal of pathology 20090101
Title: Regulation of bile acid and cholesterol metabolism by PPARs.
Journal: PPAR research 20090101
Title: Effect of oxysterol-induced apoptosis of vascular smooth muscle cells on experimental hypercholesterolemia.
Journal: Journal of biomedicine & biotechnology 20090101
Title: Cross-talk between oxysterols and glucocorticoids: differential regulation of secreted phopholipase A2 and impact on oligodendrocyte death.
Journal: PloS one 20090101
Title: Cholesterol homeostasis in two commonly used human prostate cancer cell-lines, LNCaP and PC-3.
Journal: PloS one 20090101
Title: 25-Hydroxycholesterol-3-sulfate regulates macrophage lipid metabolism via the LXR/SREBP-1 signaling pathway.
Journal: American journal of physiology. Endocrinology and metabolism 20081201
Title: Primary hepatocytes as targets for hepatitis C virus replication.
Journal: Journal of viral hepatitis 20081201
Title: Role of oxidative stress in adaptive responses in special reference to atherogenesis.
Journal: Journal of clinical biochemistry and nutrition 20081101
Title: Liquid chromatography-tandem mass spectrometry determination of plasma 24S-hydroxycholesterol with chromatographic separation of 25-hydroxycholesterol.
Journal: Analytical biochemistry 20081001
Title: CETP polymorphisms influence cholesterol metabolism but not Alzheimer's disease risk.
Journal: Brain research 20080926
Title: SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth.
Journal: Cell metabolism 20080903
Title: Activation of a caspase-3-independent mode of cell death associated with lysosomal destabilization in cultured human retinal pigment epithelial cells (ARPE-19) exposed to 7beta-hydroxycholesterol.
Journal: Current eye research 20080901
Title: Cadmium chloride-induced disruption of testicular steroidogenesis in rainbow trout, Oncorhynchus mykiss.
Journal: Archives of environmental contamination and toxicology 20080701
Title: OSBP negatively regulates ABCA1 protein stability.
Journal: The Journal of biological chemistry 20080627
Title: 25-hydroxycholesterol induces mitochondria-dependent apoptosis via activation of glycogen synthase kinase-3beta in PC12 cells.
Journal: Free radical research 20080601
Title: Cholesterol supply and SREBPs modulate transcription of the Niemann-Pick C-1 gene in steroidogenic tissues.
Journal: Journal of lipid research 20080501
Title: Ligand specificity and evolution of liver X receptors.
Journal: The Journal of steroid biochemistry and molecular biology 20080501
Title: The N terminus controls sterol binding while the C terminus regulates the scaffolding function of OSBP.
Journal: The Journal of biological chemistry 20080321
Title: Effectors of rapid homeostatic responses of endoplasmic reticulum cholesterol and 3-hydroxy-3-methylglutaryl-CoA reductase.
Journal: The Journal of biological chemistry 20080118
Title: Purified NPC1 protein. I. Binding of cholesterol and oxysterols to a 1278-amino acid membrane protein.
Journal: The Journal of biological chemistry 20080111
Title: OSBP-related protein 8 (ORP8) suppresses ABCA1 expression and cholesterol efflux from macrophages.
Journal: The Journal of biological chemistry 20080104
Title: Oxysterol-binding protein-1 (OSBP1) modulates processing and trafficking of the amyloid precursor protein.
Journal: Molecular neurodegeneration 20080101
Title: [Effects of (22S,23S)- and (22R,23R)-3beta-hydroxy-22,23-oxido-5alpha-ergost-8(14)-en-15-ones on cholesteryl esters biosynthesis and acyl-CoA:cholesterol acyl transferase activity in Hep G2 cells].
Journal: Biomeditsinskaia khimiia 20080101
Title: Different kinetics of cholesterol delivery to components of the cholesterol homeostatic machinery: implications for cholesterol trafficking to the endoplasmic reticulum.
Journal: Biochimica et biophysica acta 20080101
Title: Taurine reduces the secretion of apolipoprotein B100 and lipids in HepG2 cells.
Journal: Lipids in health and disease 20080101
Title: Liver x receptor: a novel therapeutic target.
Journal: Indian journal of pharmaceutical sciences 20080101
Title: Liver X Receptor Agonists Inhibit the Phospholipid Regulatory Gene CTP: Phosphoethanolamine Cytidylyltransferase-Pcyt2.
Journal: Research letters in biochemistry 20080101
Title: Biosynthesis of the regulatory oxysterol, 5-cholesten-3beta,25-diol 3-sulfate, in hepatocytes.
Journal: Journal of lipid research 20071201
Title: Delta5 desaturase mRNA levels are increased by simvastatin via SREBP-1 at early stages, not via PPARalpha, in THP-1 cells.
Journal: European journal of pharmacology 20071001
Title: 27-Hydroxycholesterol is an endogenous SERM that inhibits the cardiovascular effects of estrogen.
Journal: Nature medicine 20071001
Title: Sulfated oxysterol, 25HC3S, is a potent regulator of lipid metabolism in human hepatocytes.
Journal: Biochemical and biophysical research communications 20070907
Title: Ribonucleic acid binding protein-mediated regulation of luteinizing hormone receptor expression in granulosa cells: relationship to sterol metabolism.
Journal: Molecular endocrinology (Baltimore, Md.) 20070901
Title: Amplification of the gene for SCAP, coupled with Insig-1 deficiency, confers sterol resistance in mutant Chinese hamster ovary cells.
Journal: Journal of lipid research 20070901
Title: The mammalian oxysterol-binding protein-related proteins (ORPs) bind 25-hydroxycholesterol in an evolutionarily conserved pocket.
Journal: The Biochemical journal 20070801
Title: Sterol regulatory element-binding protein-2- and liver X receptor-driven dual promoter regulation of hepatic ABC transporter A1 gene expression: mechanism underlying the unique response to cellular cholesterol status.
Journal: The Journal of biological chemistry 20070720
Title: SREBP-1 regulates the expression of heme oxygenase 1 and the phosphatidylinositol-3 kinase regulatory subunit p55 gamma.
Journal: Journal of lipid research 20070701
Title: Cholesterol oxidation is increased and PUFA decreased by frozen storage and grilling of Atlantic hake fillets (Merluccius hubbsi).
Journal: Lipids 20070701
Title: Cytotoxic oxysterols induce caspase-independent myelin figure formation and caspase-dependent polar lipid accumulation.
Journal: Histochemistry and cell biology 20070601
Title: Characterization of the sterol-binding domain of oxysterol-binding protein (OSBP)-related protein 4 reveals a novel role in vimentin organization.
Journal: Experimental cell research 20070415
Title: Prevention of 7-ketocholesterol-induced mitochondrial damage and cell death by calmodulin inhibition.
Journal: Brain research 20070316
Title: The low-density lipoprotein receptor plays a role in the infection of primary human hepatocytes by hepatitis C virus.
Journal: Journal of hepatology 20070301
Title: 25-Hydroxycholesterol, 7beta-hydroxycholesterol and 7-ketocholesterol upregulate interleukin-8 expression independently of Toll-like receptor 1, 2, 4 or 6 signalling in human macrophages.
Journal: Free radical research 20070301
Title: Oxysterols induced inflammation and oxidation in primary porcine retinal pigment epithelial cells.
Journal: Current eye research 20070301
Title: Regulation of human cytochrome P450 4F2 expression by sterol regulatory element-binding protein and lovastatin.
Journal: The Journal of biological chemistry 20070223
Title: Up-regulation of skeletal muscle LIM protein 1 gene by 25-hydroxycholesterol may mediate morphological changes of rat aortic smooth muscle cells.
Journal: Life sciences 20070109
Title: Cholesterol oxides as biomarkers of oxidative stress in type 1 and type 2 diabetes mellitus.
Journal: Diabetes/metabolism research and reviews 20070101
Title: Modulation of human Niemann-Pick C1-like 1 gene expression by sterol: Role of sterol regulatory element binding protein 2.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20070101
Title: Biosynthetic capacity of rainbow trout (Oncorhynchus mykiss) interrenal tissue after cadmium exposure.
Journal: Archives of environmental contamination and toxicology 20070101
Title: Evidence for the functional role of residues in the B'-C loop of baboon cytochrome P450 side-chain cleavage (CYP11A1) obtained by site-directed mutagenesis, kinetic analysis and homology modelling.
Journal: The Journal of steroid biochemistry and molecular biology 20070101
Title: Enzymatic reduction of oxysterols impairs LXR signaling in cultured cells and the livers of mice.
Journal: Cell metabolism 20070101
Title: Synthesis of the oxysterol, 24(S), 25-epoxycholesterol, parallels cholesterol production and may protect against cellular accumulation of newly-synthesized cholesterol.
Journal: Lipids in health and disease 20070101
Title: Leptin stimulates endogenous cholesterol synthesis in human monocytes: New role of an old player in atherosclerotic plaque formation. Leptin-induced increase in cholesterol synthesis.
Journal: The international journal of biochemistry & cell biology 20070101
Title: The immune response is involved in atherosclerotic plaque calcification: could the RANKL/RANK/OPG system be a marker of plaque instability?
Journal: Clinical & developmental immunology 20070101
Title: A Chinese hamster ovarian cell line imports cholesterol by high density lipoprotein degradation.
Journal: The Journal of biological chemistry 20061215
Title: Low cell cholesterol levels increase NFkappaB activity through a p38 MAPK-dependent mechanism.
Journal: Cellular signalling 20061201
Title: Effects of crude adlay hull acetone extract on corticosterone release from rat zona fasciculata-reticularis cells.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20061101
Title: Induction of apoptosis by 25-hydroxycholesterol in adult rat Leydig cells: protective effect of 17beta-estradiol.
Journal: Reproductive toxicology (Elmsford, N.Y.) 20061101
Title: [Synthesis and structure-activity relationships of bioactive compounds using sterols].
Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20061101
Title: Neuropeptides induced a pronounced and statin-sensitive dysregulation of mevalonate cycle in human monocytes of patients with hypercholesterolemia.
Journal: Neuropeptides 20061001
Title: Oxysterol mixtures, in atheroma-relevant proportions, display synergistic and proapoptotic effects.
Journal: Free radical biology & medicine 20060915
Title: ABCA1 mediates high-affinity uptake of 25-hydroxycholesterol by membrane vesicles and rapid efflux of oxysterol by intact cells.
Journal: American journal of physiology. Cell physiology 20060901
Title: Bleomycin is a potent small-molecule inhibitor of hepatitis C virus replication.
Journal: Chembiochem : a European journal of chemical biology 20060901
Title: 25-Hydroxycholesterol has a dual effect on the proliferation of cultured rat astrocytes.
Journal: Neuropharmacology 20060801
Title: RhoA and p38 MAPK mediate apoptosis induced by cellular cholesterol depletion.
Journal: Apoptosis : an international journal on programmed cell death 20060701
Title: Sterol dependent regulation of human TM7SF2 gene expression: role of the encoded 3beta-hydroxysterol Delta14-reductase in human cholesterol biosynthesis.
Journal: Biochimica et biophysica acta 20060701
Title: Seasonal variation in calcitropic hormones and bone accrual in puberty.
Journal: The British journal of nutrition 20060701
Title: Regulation of cholesterol 25-hydroxylase expression by vitamin D3 metabolites in human prostate stromal cells.
Journal: Biochemical and biophysical research communications 20060630
Title: Formation of cholesterol oxidation products in marinated foods during heating.
Journal: Journal of agricultural and food chemistry 20060628
Title: Synthesis of ent-25-hydroxycholesterol.
Journal: Steroids 20060601
Title: Localization of StarD5 cholesterol binding protein.
Journal: Journal of lipid research 20060601
Title: HPLC method for quantification and characterization of cholesterol and its oxidation products in eggs.
Journal: Lipids 20060601
Title: A critical role for the histidine residues in the catalytic function of acyl-CoA:cholesterol acyltransferase catalysis: evidence for catalytic difference between ACAT1 and ACAT2.
Journal: FEBS letters 20060515
Title: Phase behavior of lipid monolayers containing DPPC and cholesterol analogs.
Journal: Biophysical journal 20060501
Title: Identification of a novel sulfonated oxysterol, 5-cholesten-3beta,25-diol 3-sulfonate, in hepatocyte nuclei and mitochondria.
Journal: Journal of lipid research 20060501
Title: Multiplexed flow cytometric analyses of pro- and anti-inflammatory cytokines in the culture media of oxysterol-treated human monocytic cells and in the sera of atherosclerotic patients.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Title: Cloning and characterization of a cDNA encoding cholesterol side-chain cleavage cytochrome P450 (CYP11A1): tissue-distribution and changes in the transcript abundance in ovarian tissue of Japanese eel, Anguilla japonica, during artificially induced sexual development.
Journal: The Journal of steroid biochemistry and molecular biology 20060501
Title: Cholesterol, LDL, and 25-hydroxycholesterol regulate expression of the steroidogenic acute regulatory protein in microvascular endothelial cell line (bEnd.3).
Journal: Biochemical and biophysical research communications 20060421
Title: Apoptotic effects of 25-hydroxycholesterol in immature rat Sertoli cells: prevention by 17beta-estradiol.
Journal: Reproductive toxicology (Elmsford, N.Y.) 20060401
Title: Discovery and optimization of a novel series of liver X receptor-alpha agonists.
Journal: Bioorganic & medicinal chemistry letters 20060315
Title: Analysis of oxysterols by electrospray tandem mass spectrometry.
Journal: Journal of the American Society for Mass Spectrometry 20060301
Title: Coxiella burnetii inhabits a cholesterol-rich vacuole and influences cellular cholesterol metabolism.
Journal: Cellular microbiology 20060301
Title: The influence of cholesterol and lipid metabolism on host cell structure and hepatitis C virus replication.
Journal: Biochemistry and cell biology = Biochimie et biologie cellulaire 20060201
Title: Expression and localization of PCSK9 in rat hepatic cells.
Journal: Biochemistry and cell biology = Biochimie et biologie cellulaire 20060201
Title: Effects of hydroxysterols and atorvastatin on lipopolysaccharide-induced secretion of tumor necrosis factor and interleukin-10 by mouse macrophages.
Journal: Bulletin of experimental biology and medicine 20060201
Title: Physiologic interactions between macrophages and Leydig cells.
Journal: Experimental biology and medicine (Maywood, N.J.) 20060101
Title: Sterol-regulated ubiquitination and degradation of Insig-1 creates a convergent mechanism for feedback control of cholesterol synthesis and uptake.
Journal: Cell metabolism 20060101
Title: Targeted silencing of Jab1/Csn5 in human cells downregulates SCF activity through reduction of F-box protein levels.
Journal: BMC biochemistry 20060101
Title: Receptor Ck-dependent signaling regulates hTERT gene transcription.
Journal: BMC cell biology 20060101
Title: Drug-induced activation of SREBP-controlled lipogenic gene expression in CNS-related cell lines: marked differences between various antipsychotic drugs.
Journal: BMC neuroscience 20060101
Title: Oxidized LDL, a critical factor in atherogenesis.
Journal: Cardiovascular research 20051201
Title: Combined effect of 25-hydroxycholesterol and IL-1beta on IL-8 production in human colon carcinoma cell line (Caco-2).
Journal: Inflammation 20051201
Title: Regulation of adiponectin receptor 1 in human hepatocytes by agonists of nuclear receptors.
Journal: Biochemical and biophysical research communications 20050902
Title: Sterol structure determines miscibility versus melting transitions in lipid vesicles.
Journal: Biophysical journal 20050901
Title: Structural mechanism for sterol sensing and transport by OSBP-related proteins.
Journal: Nature 20050901
Title: Human StarD5, a cytosolic StAR-related lipid binding protein.
Journal: Journal of lipid research 20050801
Title: Is C-26 hydroxylation an evolutionarily conserved steroid inactivation mechanism?
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050801
Title: Inhibition of cholesterol biosynthesis by 25-hydroxycholesterol is independent of OSBP.
Journal: Genes to cells : devoted to molecular & cellular mechanisms 20050801
Title: Insig required for sterol-mediated inhibition of Scap/SREBP binding to COPII proteins in vitro.
Journal: The Journal of biological chemistry 20050715
Title: Isolation of sterol-resistant Chinese hamster ovary cells with genetic deficiencies in both Insig-1 and Insig-2.
Journal: The Journal of biological chemistry 20050701
Title: Cholesterol modulation of the expression of mitochondrial aconitase in human prostatic carcinoma cells.
Journal: The Chinese journal of physiology 20050630
Title: Cholesterol modulates human intestinal sodium-dependent bile acid transporter.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20050501
Title: Tocotrienols reduce 25-hydroxycholesterol-induced monocyte-endothelial cell interaction by inhibiting the surface expression of adhesion molecules.
Journal: Atherosclerosis 20050501
Title: In vivo and in vitro exposures of carp and carp tissues to graded concentrations of endocrine disrupting chemicals.
Journal: Annals of the New York Academy of Sciences 20050401
Title: A new LC/APCI-MS method for the determination of cholesterol oxidation products in food.
Journal: Journal of chromatography. A 20050304
Title: Comparison of the cytotoxic, pro-oxidant and pro-inflammatory characteristics of different oxysterols.
Journal: Cell biology and toxicology 20050301
Title: Post-transcriptional regulation of apoC-I synthesis and secretion in human HepG2 cells.
Journal: Atherosclerosis 20050201
Title: Differential effects of mixtures of cholesterol oxidation products on bovine aortic endothelial cells and human monocytic U937 cells.
Journal: International journal of toxicology 20050101
Title: Cholesterol and 25-hydroxycholesterol inhibit activation of SREBPs by different mechanisms, both involving SCAP and Insigs.
Journal: The Journal of biological chemistry 20041210
Title: Translocation of phospholipase A2 to membranes by oxidized LDL and hydroxyoctadecadienoic acid to contribute to cholesteryl ester formation.
Journal: Biochimica et biophysica acta 20041108
Title: Effects of 25-hydroxycholesterol on cholesterol esterification and sterol regulatory element-binding protein processing are dissociable: implications for cholesterol movement to the regulatory pool in the endoplasmic reticulum.
Journal: The Journal of biological chemistry 20041105
Title: The influence of the amino acid substitution I98K on the catalytic activity of baboon cytochrome P450 side-chain cleavage (CYP11A1).
Journal: Endocrine research 20041101
Title: Role for sterol regulatory element-binding protein in activation of endothelial cells by phospholipid oxidation products.
Journal: Circulation research 20041015
Title: Vascular endothelial growth factor activation of sterol regulatory element binding protein: a potential role in angiogenesis.
Journal: Circulation research 20040903
Title: Platelet-derived growth factor stimulates membrane lipid synthesis through activation of phosphatidylinositol 3-kinase and sterol regulatory element-binding proteins.
Journal: The Journal of biological chemistry 20040820
Title: Mechanisms of cholesterol and sterol regulatory element binding protein regulation of the sterol 12alpha-hydroxylase gene (CYP8B1).
Journal: Biochemical and biophysical research communications 20040806
Title: Statins upregulate PCSK9, the gene encoding the proprotein convertase neural apoptosis-regulated convertase-1 implicated in familial hypercholesterolemia.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20040801
Title: 25-hydroxycholesterol acts in the Golgi compartment to induce degradation of tyrosinase.
Journal: Pigment cell research 20040801
Title: The effect of LXR activators on AP-1 proteins in keratinocytes.
Journal: The Journal of investigative dermatology 20040701
Title: Cell-based screen of HMG-CoA reductase inhibitors and expression regulators using LC-MS.
Journal: Analytical biochemistry 20040601
Title: Rat cytochrome P450C24 (CYP24A1) and the role of F249 in substrate binding and catalytic activity.
Journal: Archives of biochemistry and biophysics 20040515
Title: Sterol regulation of scavenger receptor class B type I in macrophages.
Journal: Journal of lipid research 20040501
Title: Signaling pathway of magnolol-stimulated lipolysis in sterol ester-loaded 3T3-L1 preadipocyes.
Journal: Journal of cellular biochemistry 20040401
Title: Oxysterols regulate expression of the steroidogenic acute regulatory protein.
Journal: Journal of molecular endocrinology 20040401
Title: Effect of LPS on basal and induced apo E secretion by 25-OH chol and 9cRA in differentiated CaCo-2.
Journal: Journal of cellular biochemistry 20040301
Title: Apomine, a novel hypocholesterolemic agent, accelerates degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase and stimulates low density lipoprotein receptor activity.
Journal: The Journal of biological chemistry 20040220
Title: Peroxisome proliferator-activated receptor alpha (PPARalpha) activators induce hepatic farnesyl diphosphate synthase gene expression in rodents.
Journal: The Journal of steroid biochemistry and molecular biology 20040201
Title: AKT/protein kinase B regulation of BCL family members during oxysterol-induced apoptosis.
Journal: The Journal of biological chemistry 20040109
Title: CYP3A induction by liver x receptor ligands in primary cultured rat and mouse hepatocytes is mediated by the pregnane X receptor.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20040101
Title: NFY interacts with the promoter region of two genes involved in the rat peroxisomal fatty acid beta-oxidation: the multifunctional protein type 1 and the 3-ketoacyl-CoA B thiolase.
Journal: Lipids in health and disease 20040101
Title: Analysis of cholesterol oxidation products in biological samples.
Journal: Journal of AOAC International 20040101
Title: Inhibitory effects of red wine extracts on endothelial-dependent adhesive interactions with monocytes induced by oxysterols.
Journal: Biological research 20040101
Title: Antisteroidogenic actions of hydrogen peroxide on rat Leydig cells.
Journal: Journal of cellular biochemistry 20031215
Title: Cholesterol oxides mediated changes in cytoskeletal organisation involves Rho GTPases.
Journal: Experimental cell research 20031210
Title: Steroid structural requirements for stabilizing or disrupting lipid domains.
Journal: Biochemistry 20031209
Title: Oxysterol and 9-cis-retinoic acid stimulate the group IIA secretory phospholipase A2 gene in rat smooth-muscle cells.
Journal: The Biochemical journal 20031201
Title: Effects of dehydroepiandrosterone on corticosterone release in rat zona fasciculata-reticularis cells.
Journal: Naunyn-Schmiedeberg's archives of pharmacology 20031201
Title: Identification of natural ligands of retinoic acid receptor-related orphan receptor alpha ligand-binding domain expressed in Sf9 cells--a mass spectrometry approach.
Journal: Analytical biochemistry 20031201
Title: In vivo implants of beta-sitosterol cause reductions of reactive cholesterol pools in mitochondria isolated from gonads of male goldfish (Carassius auratus).
Journal: General and comparative endocrinology 20031201
Title: Clofibrate, a peroxisome-proliferator, enhances reverse cholesterol transport through cytochrome P450 activation and oxysterol generation.
Journal: The Tohoku journal of experimental medicine 20031201
Title: Serum ferritin concentration is associated with plasma levels of cholesterol oxidation products in man.
Journal: Free radical biology & medicine 20031015
Title: 7-ketocholesterol stimulates differentiation of lens epithelial cells.
Journal: Molecular vision 20031006
Title: Origin of oxysterols in hepatic bile of patients with biliary infection.
Journal: The American journal of gastroenterology 20031001
Title: Hypoxia increases 25-hydroxycholesterol-induced interleukin-8 protein secretion in human macrophages.
Journal: Atherosclerosis 20031001
Title: Direct effect of propylthiouracil on progesterone release in rat granulosa cells.
Journal: British journal of pharmacology 20030802
Title: On the substrate specificity of human CYP27A1: implications for bile acid and cholestanol formation.
Journal: Journal of lipid research 20030801
Title: Regulation of PPAR-gamma gene in human promyelocytic HL-60 cell line.
Journal: Leukemia research 20030801
Title: Involvement of the SREBP pathway in the mode of action of androgens in sebaceous glands in vivo.
Journal: Experimental dermatology 20030801
Title: NPC1 and NPC2 regulate cellular cholesterol homeostasis through generation of low density lipoprotein cholesterol-derived oxysterols.
Journal: The Journal of biological chemistry 20030711
Title: Oxysterols suppress constitutive fibrinogen expression.
Journal: Thrombosis and haemostasis 20030701
Title: Sterol-mediated regulation of hormone-sensitive lipase in 3T3-L1 adipocytes.
Journal: Lipids 20030701
Title: Oxysterol-induced toxicity in R28 and ARPE-19 cells.
Journal: Neurochemical research 20030601
Title: PPAR agonists protect mesangial cells from interleukin 1beta-induced intracellular lipid accumulation by activating the ABCA1 cholesterol efflux pathway.
Journal: Journal of the American Society of Nephrology : JASN 20030301
Title: Seasonal alterations in adrenocortical cell function associated with stress-responsiveness and sex in the eastern fence lizard (Sceloporus undulatus).
Journal: Hormones and behavior 20030301
Title: Effects of dioxin (2,3,7,8-TCDD) and PCDDs/PCDFs congeners mixture on steroidogenesis in human placenta tissue culture.
Journal: Endocrine regulations 20030301
Title: Regulation of isoprenoid/cholesterol biosynthesis in cells from mevalonate kinase-deficient patients.
Journal: The Journal of biological chemistry 20030221
Title: Oxysterols induce apoptosis and accumulation of cell cycle at G(2)/M phase in the human monocytic THP-1 cell line.
Journal: Life sciences 20030207
Title: Liver X receptor activators display anti-inflammatory activity in irritant and allergic contact dermatitis models: liver-X-receptor-specific inhibition of inflammation and primary cytokine production.
Journal: The Journal of investigative dermatology 20030201
Title: Cholesterol cell content modulates GTPase activity of G proteins in GH4C1 cell membranes.
Journal: Cellular signalling 20030101
Title: Toxicity of cholesterol oxidation products to Caco-2 and HepG2 cells: modulatory effects of alpha- and gamma-tocopherol.
Journal: Journal of applied toxicology : JAT 20030101
Title: Cholesterol transport and steroidogenesis by the corpus luteum.
Journal: Reproductive biology and endocrinology : RB&E 20030101
Title: On the rate of translocation in vitro and kinetics in vivo of the major oxysterols in human circulation: critical importance of the position of the oxygen function.
Journal: Journal of lipid research 20021201
Title: Testosterone regulates 25-hydroxycholesterol production in testicular macrophages.
Journal: Biology of reproduction 20021101
Title: Bile acids enhance low density lipoprotein receptor gene expression via a MAPK cascade-mediated stabilization of mRNA.
Journal: The Journal of biological chemistry 20021004
Title: Dietary cholesterol-oxidation products accumulate in serum and liver in apolipoprotein E-deficient mice, but do not accelerate atherosclerosis.
Journal: The British journal of nutrition 20021001
Title: Inhibition of testosterone production by propylthiouracil in rat Leydig cells.
Journal: Biology of reproduction 20020801
Title: Cholesterol addition to ER membranes alters conformation of SCAP, the SREBP escort protein that regulates cholesterol metabolism.
Journal: Molecular cell 20020801
Title: Effect of oxysterols on hematopoietic progenitor cells.
Journal: Experimental hematology 20020701
Title: 7-Ketocholesterol and staurosporine induce opposite changes in intracellular pH, associated with distinct types of cell death in ECV304 cells.
Journal: Archives of biochemistry and biophysics 20020615
Title: Dietary cholesterol fails to stimulate the human cholesterol 7alpha-hydroxylase gene (CYP7A1) in transgenic mice.
Journal: The Journal of biological chemistry 20020607
Title: Human organic anion transporting polypeptide 8 promoter is transactivated by the farnesoid X receptor/bile acid receptor.
Journal: Gastroenterology 20020601
Title: Characterization of the estrogenic response to genistein in Japanese medaka (Oryzias latipes).
Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20020601
Title: Induction of hepatic inducible nitric oxide synthase by cholesterol in vivo and in vitro.
Journal: Experimental & molecular medicine 20020531
Title: 25-hydroxycholesterol is produced by testicular macrophages during the early postnatal period and influences differentiation of Leydig cells in vitro.
Journal: Biology of reproduction 20020501
Title: 25R,26-Hydroxycholesterol revisited: synthesis, metabolism, and biologic roles.
Journal: Journal of lipid research 20020501
Title: The cDNA cloning and tissue expression of the cytochrome P450scc from Syrian hamster (Mesocricetus auratus).
Journal: General and comparative endocrinology 20020501
Title: Cholesterol, hydroxycholesterols, and bile acids.
Journal: Biochemical and biophysical research communications 20020419
Title: Modulation of goldfish testicular testosterone production in vitro by tumor necrosis factor alpha, interleukin-1beta, and macrophage conditioned media.
Journal: The Journal of experimental zoology 20020401
Title: Lymphatic transport of dietary cholesterol oxidation products, cholesterol and triacylglycerols in rats.
Journal: Bioscience, biotechnology, and biochemistry 20020401
Title: A Link between cholesterol levels and phenobarbital induction of cytochromes P450.
Journal: Biochemical and biophysical research communications 20020222
Title: Oxysterol-binding-protein (OSBP)-related protein 4 binds 25-hydroxycholesterol and interacts with vimentin intermediate filaments.
Journal: The Biochemical journal 20020201
Title: Cellular antioxidant effects of atorvastatin in vitro and in vivo.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20020201
Title: Scavenger receptor class B type I is expressed in cultured keratinocytes and epidermis. Regulation in response to changes in cholesterol homeostasis and barrier requirements.
Journal: The Journal of biological chemistry 20020125
Title: Dissociation of apoptosis induction and CD36 upregulation by enzymatically modified low-density lipoprotein in monocytic cells.
Journal: Biochemical and biophysical research communications 20020125
Title: Induction of monocyte differentiation and foam cell formation in vitro by 7-ketocholesterol.
Journal: Journal of lipid research 20020101
Title: Oxysterols induce interleukin-1beta production in human macrophages.
Journal: European journal of clinical investigation 20020101
Title: Selective effect of cholesterylphosphoserine on intracellular cholesterol transport.
Journal: Lipids 20020101
Title: Green tea catechins decrease apolipoprotein B-100 secretion from HepG2 cells.
Journal: Molecular and cellular biochemistry 20020101
Title: The effect of Puerariae radix on lipoprotein metabolism in liver and intestinal cells.
Journal: BMC complementary and alternative medicine 20020101
Title: Adrenodoxin-cytochrome P450scc interaction as revealed by EPR spectroscopy: comparison with the putidaredoxin-cytochrome P450cam system.
Journal: Journal of biochemistry 20011201
Title: The hypocholesterolemic agent LY295427 reverses suppression of sterol regulatory element-binding protein processing mediated by oxysterols.
Journal: The Journal of biological chemistry 20011130
Title: Acid sphingomyelinase-deficient macrophages have defective cholesterol trafficking and efflux.
Journal: The Journal of biological chemistry 20011130
Title: 7-Ketocholesterol forms crystalline domains in model membranes and murine aortic smooth muscle cells.
Journal: Atherosclerosis 20011101
Title: Growth modulation of low density lipoprotein receptor sterol sensitivity in cultured human fibroblasts.
Journal: Lipids 20011101
Title: Molecular cloning and structural analysis of human sterol C5 desaturase.
Journal: Biochimica et biophysica acta 20011031
Title: Inhibition of the mitogen activated protein kinase, p38 alpha, prevents proinflammatory cytokine induction by human adherent mononuclear leukocytes in response to lipid loading.
Journal: Atherosclerosis 20011001
Title: Arachidonate metabolism and the signaling pathway of induction of apoptosis by oxidized LDL/oxysterol.
Journal: Journal of lipid research 20011001
Title: Regulation of sterol regulatory element-binding proteins by cholesterol flux in CaCo-2 cells.
Journal: Journal of lipid research 20011001
Title: 25-hydroxycholesterol induces lipopolysaccharide-tolerance and decreases a lipopolysaccharide-induced TNF-alpha secretion in macrophages.
Journal: Atherosclerosis 20010901
Title: Binding and uptake of chylomicron remnants by primary and THP-1 human monocyte-derived macrophages: determination of binding proteins.
Journal: Clinical science (London, England : 1979) 20010801
Title: [Studies on the mechanism of arterial in vitro calcification].
Journal: Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20010801
Title: Woc (without children) gene control of ecdysone biosynthesis in Drosophila melanogaster.
Journal: Molecular and cellular endocrinology 20010705
Title: Concerted transcriptional activation of the low density lipoprotein receptor gene by insulin and luteinizing hormone in cultured porcine granulosa-luteal cells: possible convergence of protein kinase a, phosphatidylinositol 3-kinase, and mitogen-activated protein kinase signaling pathways.
Journal: Endocrinology 20010701
Title: Fatty acid modifications and cholesterol oxidation in pork loin during frying at different temperatures.
Journal: Journal of food protection 20010701
Title: Neurosteroid hydroxylase CYP7B: vivid reporter activity in dentate gyrus of gene-targeted mice and abolition of a widespread pathway of steroid and oxysterol hydroxylation.
Journal: The Journal of biological chemistry 20010629
Title: Plant sterols regulate rat vascular smooth muscle cell growth and prostacyclin release in culture.
Journal: Prostaglandins, leukotrienes, and essential fatty acids 20010601
Title: Stimulatory effect of lactate on testosterone production by rat Leydig cells.
Journal: Journal of cellular biochemistry 20010601
Title: Novel members of the human oxysterol-binding protein family bind phospholipids and regulate vesicle transport.
Journal: The Journal of biological chemistry 20010525
Title: Selective distribution of oxysterols in atherosclerotic lesions and human plasma lipoproteins.
Journal: Free radical research 20010501
Title: An oxidized derivative of cholesterol increases the release of soluble vascular cell adhesion molecule-1 from human umbilical vein endothelial cells in culture.
Journal: Biochimica et biophysica acta 20010430
Title: Differential modulation of ACAT1 and ACAT2 transcription and activity by long chain free fatty acids in cultured cells.
Journal: Biochemistry 20010417
Title: cyp7b1 catalyses the 7alpha-hydroxylation of dehydroepiandrosterone and 25-hydroxycholesterol in rat prostate.
Journal: The Biochemical journal 20010415
Title: Coronary atherosclerosis and oxidative stress as reflected by autoantibodies against oxidized low-density lipoprotein and oxysterols.
Journal: Atherosclerosis 20010401
Title: Key regulatory oxysterols in liver: analysis as delta4-3-ketone derivatives by HPLC and response to physiological perturbations.
Journal: Journal of lipid research 20010401
Title: Direct inhibitory effect of digitalis on progesterone release from rat granulosa cells.
Journal: British journal of pharmacology 20010401
Title: Pharmacophore analysis of the nuclear oxysterol receptor LXRalpha.
Journal: Journal of medicinal chemistry 20010315
Title: Fas/Fas ligand-mediated death pathway is involved in oxLDL-induced apoptosis in vascular smooth muscle cells.
Journal: American journal of physiology. Cell physiology 20010301
Title: Production of 25-hydroxycholesterol by testicular macrophages and its effects on Leydig cells.
Journal: Biology of reproduction 20010301
Title: Control of apolipoprotein E secretion in the human hepatoma cell line KYN-2.
Journal: Cell biochemistry and function 20010301
Title: Cholesterol biosynthesis from lanosterol: molecular cloning, chromosomal localization, functional expression and liver-specific gene regulation of rat sterol delta8-isomerase, a cholesterogenic enzyme with multiple functions.
Journal: The Biochemical journal 20010201
Title: Mechanism of action of noradrenaline on secretion of progesterone and oxytocin by the bovine corpus luteum in vitro.
Journal: Acta veterinaria Hungarica 20010101
Title: Comparative study of the cytotoxicity and apoptosis-inducing potential of commonly occurring oxysterols.
Journal: Cell biology and toxicology 20010101
Title: Control of apolipoprotein E secretion by 25-hydroxycholesterol and proinflammatory cytokines in the human astrocytoma cell line CCF-STTG1.
Journal: Cell biology and toxicology 20010101
Title: Peroxisome proliferator-activated receptor agonists prevent 25-OH-cholesterol induced c-jun activation and cell death.
Journal: BMC pharmacology 20010101
Title: Oxysterol 7 alpha-hydroxylase activity by cholesterol 7 alpha-hydroxylase (CYP7A).
Journal: The Journal of biological chemistry 20001103
Title: Expression cloning of an oxysterol 7alpha-hydroxylase selective for 24-hydroxycholesterol.
Journal: The Journal of biological chemistry 20000602
Title: The mevalonate/isoprenoid pathway inhibitor apomine (SR-45023A) is antiproliferative and induces apoptosis similar to farnesol.
Journal: Biochemical and biophysical research communications 20000402
Title: Down-regulation of mammalian 3-hydroxy-3-methylglutaryl coenzyme A reductase activity with highly purified liposomal cholesterol.
Journal: European journal of biochemistry 19991201
Title: Oxysterol regulation of steroidogenic acute regulatory protein gene expression. Structural specificity and transcriptional and posttranscriptional actions.
Journal: The Journal of biological chemistry 19981113
Title: Oxysterols, but not cholesterol, inhibit human immunodeficiency virus replication in vitro.
Journal: Antiviral chemistry & chemotherapy 19981101
Title: Meiosis-activating sterol promotes resumption of meiosis in mouse oocytes cultured in vitro in contrast to related oxysterols.
Journal: Biology of reproduction 19980501
Title: Activation of the orphan nuclear receptor steroidogenic factor 1 by oxysterols.
Journal: Proceedings of the National Academy of Sciences of the United States of America 19970513
Title: Studies on the relationships between 7 alpha-hydroxylation and the ability of 25- and 27-hydroxycholesterol to suppress the activity of HMG-CoA reductase.
Journal: Biochimica et biophysica acta 19970218
Title: Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway.
Journal: The Journal of biological chemistry 19970207
Title: Oxysterols present in atherosclerotic tissue decrease the expression of lipoprotein lipase messenger RNA in human monocyte-derived macrophages.
Journal: The Journal of clinical investigation 19960115
Title: Effects of 26-aminocholesterol, 27-hydroxycholesterol, and 25-hydroxycholesterol on proliferation and cholesterol homeostasis in arterial myocytes.
Journal: Arteriosclerosis, thrombosis, and vascular biology 19950301
Title: Structural specificity in the suppression of HMG-CoA reductase in human fibroblasts by intermediates in bile acid biosynthesis.
Journal: Journal of lipid research 19950201
Title: 7 alpha hydroxylation of 25-hydroxycholesterol in liver microsomes. Evidence that the enzyme involved is different from cholesterol 7 alpha-hydroxylase.
Journal: European journal of biochemistry 19940901
Title: Atherosclerosis and sterol 27-hydroxylase: evidence for a role of this enzyme in elimination of cholesterol from human macrophages.
Journal: Proceedings of the National Academy of Sciences of the United States of America 19940830
Title: 24-, 25- and 27-hydroxylation of cholesterol by a purified preparation of 27-hydroxylase from pig liver.
Journal: Biochimica et biophysica acta 19930224
Title: McDonald JG, et al. Editorial: 25-Hydroxycholesterol: a new life in immunology. J Leukoc Biol. 2010 Dec;88(6):1071-2.
