Title: EGFR participates downstream of ERα in estradiol-17β-D-glucuronide-induced impairment of Abcc2 function in isolated rat hepatocyte couplets.
Journal: Archives of toxicology 20160401
Title: Pb²⁺ induced IL-8 gene expression by extracellular signal-regulated kinases and the transcription factor, activator protein 1, in human gastric carcinoma cells.
Journal: Environmental toxicology 20150301
Title: Detrimental effects of Notch1 signaling activated by cadmium in renal proximal tubular epithelial cells.
Journal: Cell death & disease 20140801
Title: Hexabromocyclododecane facilitates FSH activation of ERK1/2 and AKT through epidermal growth factor receptor in rat granulosa cells.
Journal: Archives of toxicology 20140201
Title: Oxidative DNA damage and mammary cell proliferation by alcohol-derived salsolinol.
Journal: Chemical research in toxicology 20131021
Title: EGFR and PKC are involved in the activation of ERK1/2 and p90 RSK and the subsequent proliferation of SNU-407 colon cancer cells by muscarinic acetylcholine receptors.
Journal: Molecular and cellular biochemistry 20121101
Title: The tyrphostin AG1478 augments oridonin-induced A431 cell apoptosis by blockage of JNK MAPK and enhancement of oxidative stress.
Journal: Free radical research 20121101
Title: Autocrine effect of EGFR ligands on the pro-inflammatory response induced by PM(2.5) exposure in human bronchial epithelial cells.
Journal: Archives of toxicology 20121001
Title: Thrombin induces epidermal growth factor receptor transactivation and CCL2 expression in human osteoblasts.
Journal: Arthritis and rheumatism 20121001
Title: Cardiotoxin III suppresses MDA-MB-231 cell metastasis through the inhibition of EGF/EGFR-mediated signaling pathway.
Journal: Toxicon : official journal of the International Society on Toxinology 20121001
Title: A novel epidermal growth factor-dependent extracellular signal-regulated MAP kinase cascade involved in sperm functionality in sheep.
Journal: Biology of reproduction 20121001
Title: Ligand-dependent EGFR activation induces the co-expression of IL-6 and PAI-1 via the NFkB pathway in advanced-stage epithelial ovarian cancer.
Journal: Oncogene 20120913
Title: Indoxyl sulfate enhances angiotensin II signaling through upregulation of epidermal growth factor receptor expression in vascular smooth muscle cells.
Journal: Life sciences 20120904
Title: Effect of EGF-receptor tyrosine kinase inhibitor on Rab5 function during endocytosis.
Journal: Archives of biochemistry and biophysics 20120901
Title: Regulated intramembrane cleavage of the EGF receptor.
Journal: Traffic (Copenhagen, Denmark) 20120801
Title: The EGFR tyrosine kinase inhibitor tyrphostin AG-1478 causes hypomagnesemia and cardiac dysfunction.
Journal: Canadian journal of physiology and pharmacology 20120801
Title: Simultaneous inhibition of EGFR and PI3K enhances radiosensitivity in human breast cancer.
Journal: International journal of radiation oncology, biology, physics 20120701
Title: A novel role for epidermal growth factor receptor tyrosine kinase and its downstream endoplasmic reticulum stress in cardiac damage and microvascular dysfunction in type 1 diabetes mellitus.
Journal: Hypertension (Dallas, Tex. : 1979) 20120701
Title: Increased activation of fibrocytes in patients with chronic obstructive asthma through an epidermal growth factor receptor-dependent pathway.
Journal: The Journal of allergy and clinical immunology 20120501
Title: Neutrophil gelatinase-associated lipocalin (NGAL) expression is dependent on the tumor-associated sigma-2 receptor S2RPgrmc1.
Journal: The Journal of biological chemistry 20120427
Title: Tyrosine kinase inhibitors influence ABCG2 expression in EGFR-positive MDCK BCRP cells via the PI3K/Akt signaling pathway.
Journal: ChemMedChem 20120401
Title: Angiotensin AT1 receptor blockers suppress oxidized low-density lipoprotein-derived formation of foam cells.
Journal: European journal of pharmacology 20120315
Title: Angiotensin-(1-7) inhibits epidermal growth factor receptor transactivation via a Mas receptor-dependent pathway.
Journal: British journal of pharmacology 20120301
Title: Ovarian expression and regulation of the stromelysins during the periovulatory period in the human and the rat.
Journal: Biology of reproduction 20120301
Title: ErbB4 localization to cardiac myocyte nuclei, and its role in myocyte DNA damage response.
Journal: Biochemical and biophysical research communications 20120203
Title: Combined treatment of curcumin and small molecule inhibitors suppresses proliferation of A549 and H1299 human non-small-cell lung cancer cells.
Journal: Phytotherapy research : PTR 20120101
Title: Effect of bisphenol A on the EGFR-STAT3 pathway in MCF-7 breast cancer cells.
Journal: Molecular medicine reports 20120101
Title: Inhibition of Lassa virus and Ebola virus infection in host cells treated with the kinase inhibitors genistein and tyrphostin.
Journal: Archives of virology 20120101
Title: EGF receptor inhibitors increase ErbB3 mRNA and protein levels in breast cancer cells.
Journal: Cellular signalling 20120101
Title: An in vivo C. elegans model system for screening EGFR-inhibiting anti-cancer drugs.
Journal: PloS one 20120101
Title: The EGF receptor and HER2 participate in TNF-α-dependent MAPK activation and IL-8 secretion in intestinal epithelial cells.
Journal: Mediators of inflammation 20120101
Title: Specific protein kinase C isoforms α and βI are involved in follicle-stimulating hormone-induced mouse follicle-enclosed oocytes meiotic resumption.
Journal: PloS one 20120101
Title: Neuregulin 1 regulates excitability of fast-spiking neurons through Kv1.1 and acts in epilepsy.
Journal: Nature neuroscience 20111211
Title: Cytosolic phospholipase A(2)α protects against Fas- but not LPS-induced liver injury.
Journal: Journal of hepatology 20111201
Title: The tyrphostin AG1478 inhibits proliferation and induces death of liver tumor cells through EGF receptor-dependent and independent mechanisms.
Journal: Biochemical pharmacology 20111201
Title: Insulin contributes to fine-tuning of the pancreatic beta-cell response to glucagon-like peptide-1.
Journal: Molecules and cells 20111031
Title: Bile acids promote HCV replication through the EGFR/ERK pathway in replicon-harboring cells.
Journal: Intervirology 20111001
Title: Mislocalization of large ARF-GEFs as a potential mechanism for BFA resistance in COG-deficient cells.
Journal: Experimental cell research 20111001
Title: The balance between 4-hydroxynonenal and intrinsic glutathione/glutathione S-transferase A4 system may be critical for the epidermal growth factor receptor phosphorylation of human esophageal squamous cell carcinomas.
Journal: Molecular carcinogenesis 20111001
Title: ADAM-17/tumor necrosis factor-α-converting enzyme inhibits neurogenesis and promotes gliogenesis from neural stem cells.
Journal: Stem cells (Dayton, Ohio) 20111001
Title: Epigen is induced during the interleukin-13-stimulated cell proliferation in murine primary airway epithelial cells.
Journal: Experimental lung research 20111001
Title: Epidermal growth factor receptor promotes glomerular injury and renal failure in rapidly progressive crescentic glomerulonephritis.
Journal: Nature medicine 20111001
Title: ERK phosphorylation predicts synergism between gemcitabine and the epidermal growth factor receptor inhibitor AG1478.
Journal: Lung cancer (Amsterdam, Netherlands) 20110901
Title: Epithelial growth factor receptor tyrosine kinase inhibitor prevents infiltration and cerebrospinal fluid dissemination in malignant glioma: an experimental study.
Journal: Neurosurgery 20110801
Title: EGFR gene amplification is related to adverse clinical outcomes in cervical squamous cell carcinoma, making the EGFR pathway a novel therapeutic target.
Journal: British journal of cancer 20110726
Title: Nanospheres delivering the EGFR TKI AG1478 promote optic nerve regeneration: the role of size for intraocular drug delivery.
Journal: ACS nano 20110628
Title: Small tyrosine kinase inhibitors interrupt EGFR signaling by interacting with erbB3 and erbB4 in glioblastoma cell lines.
Journal: Experimental cell research 20110610
Title: Role of somatostatin receptor 1 and 5 on epidermal growth factor receptor mediated signaling.
Journal: Biochimica et biophysica acta 20110601
Title: GPCR/EGFR cross talk is conserved in gonadal and adrenal steroidogenesis but is uniquely regulated by matrix metalloproteinases 2 and 9 in the ovary.
Journal: Molecular endocrinology (Baltimore, Md.) 20110601
Title: Activation of cumulus cell SMAD2/3 and epidermal growth factor receptor pathways are involved in porcine oocyte-cumulus cell expansion and steroidogenesis.
Journal: Molecular reproduction and development 20110601
Title: Colon-specific delivery of a probiotic-derived soluble protein ameliorates intestinal inflammation in mice through an EGFR-dependent mechanism.
Journal: The Journal of clinical investigation 20110601
Title: Expression and regulation of amphiregulin in Gsα-mutated human bone marrow stromal cells of fibrous dysplasia of mandible.
Journal: Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20110501
Title: Endosomal signalling of epidermal growth factor receptors contributes to EGF-stimulated cell cycle progression in primary hepatocytes.
Journal: European journal of pharmacology 20110305
Title: Epidermal growth factor receptor as a target for anti-proliferative treatment of proliferative cholangitis in hepatolithiasis.
Journal: The Journal of surgical research 20110301
Title: Epidermal growth factor treatment switches δ-opioid receptor-stimulated extracellular signal-regulated kinases 1 and 2 signaling from an epidermal growth factor to an insulin-like growth factor-1 receptor-dependent mechanism.
Journal: Molecular pharmacology 20110201
Title: Mechanisms of myogenic tone of coronary arteriole: Role of down stream signaling of the EGFR tyrosine kinase.
Journal: Microvascular research 20110101
Title: EGF receptor exposed to oxidative stress acquires abnormal phosphorylation and aberrant activated conformation that impairs canonical dimerization.
Journal: PloS one 20110101
Title: Inhibition of radiation induced migration of human head and neck squamous cell carcinoma cells by blocking of EGF receptor pathways.
Journal: BMC cancer 20110101
Title: Versican G3 domain modulates breast cancer cell apoptosis: a mechanism for breast cancer cell response to chemotherapy and EGFR therapy.
Journal: PloS one 20110101
Title: The prostaglandin E2 receptor, EP2, stimulates keratinocyte proliferation in mouse skin by G protein-dependent and {beta}-arrestin1-dependent signaling pathways.
Journal: The Journal of biological chemistry 20101217
Title: Role of matrix metalloproteinase-9 dimers in cell migration: design of inhibitory peptides.
Journal: The Journal of biological chemistry 20101112
Title: Increased Na, K-ATPase alpha2 isoform gene expression by ammonia in astrocytes and in brain in vivo.
Journal: Neurochemistry international 20101101
Title: Serotonin increases ERK1/2 phosphorylation in astrocytes by stimulation of 5-HT2B and 5-HT2C receptors.
Journal: Neurochemistry international 20101101
Title: Downregulated ABCG2 enhances sensitivity to topoisomerase I inhibitor in epidermal growth factor receptor tyrosine kinase inhibitor-resistant non-small cell lung cancer.
Journal: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20101101
Title: α1-Adrenoceptor-mediated contraction of rat aorta is partly mediated via transactivation of the epidermal growth factor receptor.
Journal: British journal of pharmacology 20101101
Title: Epidermal growth factor receptor transactivation by the cannabinoid receptor (CB1) and transient receptor potential vanilloid 1 (TRPV1) induces differential responses in corneal epithelial cells.
Journal: Experimental eye research 20100901
Title: Inhibition of EGFR signaling augments oridonin-induced apoptosis in human laryngeal cancer cells via enhancing oxidative stress coincident with activation of both the intrinsic and extrinsic apoptotic pathways.
Journal: Cancer letters 20100828
Title: Epidermal hyperproliferation in mice lacking fatty acid transport protein 4 (FATP4) involves ectopic EGF receptor and STAT3 signaling.
Journal: Developmental biology 20100815
Title: Modulation of the oncogene-dependent tissue factor expression by kinase suppressor of ras 1.
Journal: Thrombosis research 20100701
Title: [Effects of EGFR inhibitor AG1478 in combination with celecoxib on the growth of gastric cancer cells].
Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20100701
Title: Epidermal growth factor receptor is a co-receptor for adeno-associated virus serotype 6.
Journal: Nature medicine 20100601
Title: The antimicrobial peptide LL37 induces the migration of human pulp cells: a possible adjunct for regenerative endodontics.
Journal: Journal of endodontics 20100601
Title: Activated EGFR signaling increases proliferation, survival, and migration and blocks neuronal differentiation in post-natal neural stem cells.
Journal: Journal of neuro-oncology 20100501
Title: New platform for controlled and sustained delivery of the EGF receptor tyrosine kinase inhibitor AG1478 using poly(lactic-co-glycolic acid) microspheres.
Journal: Journal of microencapsulation 20100501
Title: Hypoxia-induced proliferation of human pulmonary microvascular endothelial cells depends on epidermal growth factor receptor tyrosine kinase activation.
Journal: American journal of physiology. Lung cellular and molecular physiology 20100401
Title: Angiotensin-induced EGF receptor transactivation inhibits insulin signaling in C9 hepatic cells.
Journal: Biochemical pharmacology 20100301
Title: Cell-type-specific roles of IGF-1R and EGFR in mediating Zn2+-induced ERK1/2 and PKB phosphorylation.
Journal: Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20100301
Title: The EGF receptor-sox2-EGF receptor feedback loop positively regulates the self-renewal of neural precursor cells.
Journal: Stem cells (Dayton, Ohio) 20100201
Title: Effect of urotensin II on PC12 rat pheochromocytoma cells.
Journal: Journal of neuroendocrinology 20100201
Title: [Effect of epidermal growth factor receptor on airway remodeling in asthmatic mice and its mechanism].
Journal: Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20100201
Title: Nanoscale imaging of epidermal growth factor receptor clustering: effects of inhibitors.
Journal: The Journal of biological chemistry 20100129
Title: Differential contribution of direct-developing and stem cell-derived melanocytes to the zebrafish larval pigment pattern.
Journal: Developmental biology 20100115
Title: Angiotensin II-induced migration of vascular smooth muscle cells is mediated by p38 mitogen-activated protein kinase-activated c-Src through spleen tyrosine kinase and epidermal growth factor receptor transactivation.
Journal: The Journal of pharmacology and experimental therapeutics 20100101
Title: Protein kinase D stabilizes aldosterone-induced ERK1/2 MAP kinase activation in M1 renal cortical collecting duct cells to promote cell proliferation.
Journal: The Journal of steroid biochemistry and molecular biology 20100101
Title: JNK mitogen-activated protein kinase limits calcium-dependent chloride secretion across colonic epithelial cells.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20100101
Title: Cross-talk between bradykinin and epidermal growth factor in regulating IL-6 production in human airway smooth muscle cells.
Journal: Chang Gung medical journal 20100101
Title: EGFR signaling is differentially activated in patient-derived glioblastoma stem cells.
Journal: Journal of experimental therapeutics & oncology 20100101
Title: Termination of tyrphostin AG1478 application results in different recovery of EGF receptor tyrosine residues 1045 and 1173 phosphorylation in A431 cells.
Journal: Cell biology international 20091216
Title: Quercetin stimulates Na+/K+/2Cl- cotransport via PTK-dependent mechanisms in human airway epithelium.
Journal: American journal of respiratory cell and molecular biology 20091201
Title: ERK phosphorylation in intact, adult brain by alpha(2)-adrenergic transactivation of EGF receptors.
Journal: Neurochemistry international 20091201
Title: Contribution of epidermal growth factor receptor transactivation in angiotensin II-induced enhanced expression of Gi protein and proliferation in A10 vascular smooth muscle cells.
Journal: Canadian journal of physiology and pharmacology 20091201
Title: Role of epidermal growth factor receptor in ovine fetal pulmonary vascular remodeling following exposure to high altitude long-term hypoxia.
Journal: High altitude medicine & biology 20091201
Title: Evodiamine inhibits adipogenesis via the EGFR-PKCalpha-ERK signaling pathway.
Journal: FEBS letters 20091119
Title: Suppression of ErbB-2 in androgen-independent human prostate cancer cells enhances cytotoxic effect by gemcitabine in an androgen-reduced environment.
Journal: Cancer letters 20091118
Title: Role of epidermal growth factor receptor (EGFR) in corneal remodelling in diabetes.
Journal: Acta ophthalmologica 20091101
Title: Naegleria fowleri induces MUC5AC and pro-inflammatory cytokines in human epithelial cells via ROS production and EGFR activation.
Journal: Microbiology (Reading, England) 20091101
Title: Multipathway kinase signatures of multipotent stromal cells are predictive for osteogenic differentiation: tissue-specific stem cells.
Journal: Stem cells (Dayton, Ohio) 20091101
Title: Off-target effects of epidermal growth factor receptor antagonists mediate retinal ganglion cell disinhibited axon growth.
Journal: Brain : a journal of neurology 20091101
Title: Epidermal growth factor receptor inhibitors promote CNS axon growth through off-target effects on glia.
Journal: Neurobiology of disease 20091001
Title: Effects of cigarette smoking on mucin production in human middle ear epithelial cells.
Journal: International journal of pediatric otorhinolaryngology 20091001
Title: Desmoid cell motility is induced in vitro by rhEGF.
Journal: Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20090901
Title: Cyclooxygenase-2 prevents fas-induced liver injury through up-regulation of epidermal growth factor receptor.
Journal: Hepatology (Baltimore, Md.) 20090901
Title: EGFR-PLCgamma1 signaling mediates high glucose-induced PKCbeta1-Akt activation and collagen I upregulation in mesangial cells.
Journal: American journal of physiology. Renal physiology 20090901
Title: Regulation and function of tissue inhibitor of metalloproteinase (TIMP) 1 and TIMP3 in periovulatory rat granulosa cells.
Journal: Endocrinology 20090801
Title: Dexamethasone enhances basal and TNF-alpha-stimulated production of PAI-1 via the glucocorticoid receptor regardless of 11beta-hydroxysteroid dehydrogenase 2 status in human proximal renal tubular cells.
Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090601
Title: A role for Gab1/SHP2 in thrombin activation of PAK1: gene transfer of kinase-dead PAK1 inhibits injury-induced restenosis.
Journal: Circulation research 20090508
Title: Proliferative capacity of vein graft smooth muscle cells and fibroblasts in vitro correlates with graft stenosis.
Journal: Journal of vascular surgery 20090501
Title: Cell migration in response to the amino-terminal fragment of urokinase requires epidermal growth factor receptor activation through an ADAM-mediated mechanism.
Journal: Journal of vascular surgery 20090501
Title: Receptor tyrosine kinases as mediators of injury-induced bradykinin B1 receptor expression in rabbit aortic smooth muscle.
Journal: European journal of pharmacology 20090315
Title: Epidermal growth factor receptor is involved in clusterin-induced astrocyte proliferation.
Journal: Neuroreport 20090304
Title: Inhibiting the function of ABCB1 and ABCG2 by the EGFR tyrosine kinase inhibitor AG1478.
Journal: Biochemical pharmacology 20090301
Title: Epidermal growth factor receptor lacking C-terminal autophosphorylation sites retains signal transduction and high sensitivity to epidermal growth factor receptor tyrosine kinase inhibitor.
Journal: Cancer science 20090301
Title: Genistein decreases androgen biosynthesis in rat Leydig cells by interference with luteinizing hormone-dependent signaling.
Journal: Toxicology letters 20090210
Title: The inhibition of the epidermal growth factor (EGF) pathway enhances TGF-beta-induced apoptosis in rat hepatoma cells through inducing oxidative stress coincident with a change in the expression pattern of the NADPH oxidases (NOX) isoforms.
Journal: Biochimica et biophysica acta 20090201
Title: The epidermal growth factor tyrosine kinase inhibitor AG1478 and erlotinib reverse ABCG2-mediated drug resistance.
Journal: Oncology reports 20090201
Title: Estradiol, progesterone, and transforming growth factor alpha regulate insulin-like growth factor binding protein-3 (IGFBP3) expression in mouse endometrial cells.
Journal: Zoological science 20090201
Title: Tumor necrosis factor-alpha-stimulated membrane type 1-matrix metalloproteinase production is modulated by epidermal growth factor receptor signaling in human gingival fibroblasts.
Journal: Journal of periodontal research 20090201
Title: TRAIL induces apoptosis in triple-negative breast cancer cells with a mesenchymal phenotype.
Journal: Breast cancer research and treatment 20090101
Title: Arsenite suppresses Notch1 signaling in human keratinocytes.
Journal: The Journal of investigative dermatology 20090101
Title: Therapeutic efficacy of 177Lu-CHX-A''-DTPA-hu3S193 radioimmunotherapy in prostate cancer is enhanced by EGFR inhibition or docetaxel chemotherapy.
Journal: The Prostate 20090101
Title: Expression pattern and functional relevance of epidermal growth factor receptor and cyclooxygenase-2: novel chemotherapeutic targets in pancreatic endocrine tumors?
Journal: The American journal of gastroenterology 20090101
Title: Global upregulation of gene expression associated with renal dysfunction in DOCA-salt-induced hypertensive rats occurs via signaling cascades involving epidermal growth factor receptor: a microarray analysis.
Journal: Vascular pharmacology 20090101
Title: [Effects of theaflavins on the signal transduction pathway of epidermal growth factor receptor in airway mucous hypersecretion].
Journal: Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20090101
Title: [Analysis of tyrphostin AG1478 effect on behavior of internalized EGF receptor at different stages of endocytosis].
Journal: Tsitologiia 20090101
Title: Lysophosphatidic acid receptor 2 and Gi/Src pathway mediate cell motility through cyclooxygenase 2 expression in CAOV-3 ovarian cancer cells.
Journal: Experimental & molecular medicine 20081231
Title: Fluoxetine-mediated 5-HT2B receptor stimulation in astrocytes causes EGF receptor transactivation and ERK phosphorylation.
Journal: Psychopharmacology 20081201
Title: Delta-opioid receptors activate ERK/MAP kinase via integrin-stimulated receptor tyrosine kinases.
Journal: Cellular signalling 20081201
Title: Epidermal growth factor receptor (EGFR) regulates mechanical ventilation-induced lung injury in mice.
Journal: Translational research : the journal of laboratory and clinical medicine 20081201
Title: c-Fos overexpression increases the proliferation of human hepatocytes by stabilizing nuclear Cyclin D1.
Journal: World journal of gastroenterology 20081107
Title: The epidermal growth factor receptor mediates allergic airway remodelling in the rat.
Journal: The European respiratory journal 20081101
Title: The transactivated epidermal growth factor receptor recruits Pyk2 to regulate Src kinase activity.
Journal: The Journal of biological chemistry 20081010
Title: DNA vaccination controls Her-2+ tumors that are refractory to targeted therapies.
Journal: Cancer research 20080915
Title: EGF mediates calcium-activated chloride channel activation in the human bronchial epithelial cell line 16HBE14o-: involvement of tyrosine kinase p60c-src.
Journal: American journal of physiology. Lung cellular and molecular physiology 20080901
Title: Photodynamic targeting of EGFR does not predict the treatment outcome in combination with the EGFR tyrosine kinase inhibitor Tyrphostin AG1478.
Journal: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20080901
Title: In human entrocytes, GLN transport and ASCT2 surface expression induced by short-term EGF are MAPK, PI3K, and Rho-dependent.
Journal: Digestive diseases and sciences 20080801
Title: Pregnancy-upregulated nonubiquitous calmodulin kinase induces ligand-independent EGFR degradation.
Journal: American journal of physiology. Cell physiology 20080801
Title: Insulin-induced epidermal growth factor activation in vascular smooth muscle cells is ADAM-dependent.
Journal: Surgery 20080801
Title: Stimulation by vasopressin of ERK phosphorylation and vector-driven water flux in astrocytes is transactivation-dependent.
Journal: European journal of pharmacology 20080610
Title: Involvement of tyrosine kinase in the hyposmotic stimulation of I Ks in guinea-pig ventricular myocytes.
Journal: Pflugers Archiv : European journal of physiology 20080601
Title: MMP-12 induces IL-8/CXCL8 secretion through EGFR and ERK1/2 activation in epithelial cells.
Journal: American journal of physiology. Lung cellular and molecular physiology 20080601
Title: Inhibition of the EGF receptor blocks autocrine growth and increases the cytotoxic effects of doxorubicin in rat hepatoma cells: role of reactive oxygen species production and glutathione depletion.
Journal: Biochemical pharmacology 20080515
Title: PI3-kinase and mitogen-activated protein kinase in cumulus cells mediate EGF-induced meiotic resumption of porcine oocyte.
Journal: Domestic animal endocrinology 20080501
Title: Tumor necrosis factor-alpha enhances neutrophil adhesiveness: induction of vascular cell adhesion molecule-1 via activation of Akt and CaM kinase II and modifications of histone acetyltransferase and histone deacetylase 4 in human tracheal smooth muscle cells.
Journal: Molecular pharmacology 20080501
Title: Chronic pharmacologic inhibition of EGFR leads to cardiac dysfunction in C57BL/6J mice.
Journal: Toxicology and applied pharmacology 20080501
Title: Epidermal growth factor receptor activation by protein kinase C is necessary for FSH-induced meiotic resumption in porcine cumulus-oocyte complexes.
Journal: The Journal of endocrinology 20080501
Title: Targeting EGFR activity in blood vessels is sufficient to inhibit tumor growth and is accompanied by an increase in VEGFR-2 dependence in tumor endothelial cells.
Journal: Microvascular research 20080501
Title: Epidermal growth factor plays a crucial role in mitogenic regulation of human brain tumor stem cells.
Journal: The Journal of biological chemistry 20080418
Title: Lipopolysaccharide induces VCAM-1 expression and neutrophil adhesion to human tracheal smooth muscle cells: involvement of Src/EGFR/PI3-K/Akt pathway.
Journal: Toxicology and applied pharmacology 20080415
Title: Epidermal growth factor receptor inhibitors enhance susceptibility to Fas-mediated apoptosis in oral squamous cell carcinoma cells.
Journal: Oral oncology 20080401
Title: Luteinizing hormone signaling in preovulatory follicles involves early activation of the epidermal growth factor receptor pathway.
Journal: Molecular endocrinology (Baltimore, Md.) 20080401
Title: Role of epidermal growth factor gene in the development of pancreatic cancer and efficiency of inhibitors of this gene in the treatment of pancreatic carcinoma.
Journal: Bulletin of experimental biology and medicine 20080401
Title: Heparin-binding epidermal growth factor and Src family kinases in proliferation of renal epithelial cells.
Journal: American journal of physiology. Renal physiology 20080301
Title: EGFR inhibitor enhances cisplatin sensitivity of oral squamous cell carcinoma cell lines.
Journal: Pathology oncology research : POR 20080301
Title: Ebselen, a redox regulator containing a selenium atom, induces neurofilament M expression in cultured rat pheochromocytoma PC12 cells via activation of mitogen-activated protein kinase.
Journal: Journal of neuroscience research 20080215
Title: Prostaglandin E2 upregulates EGF-stimulated signaling in mitogenic pathways involving Akt and ERK in hepatocytes.
Journal: Journal of cellular physiology 20080201
Title: Thrombin increases hyposmotic taurine efflux and accelerates ICI-swell and RVD in 3T3 fibroblasts by a src-dependent EGFR transactivation.
Journal: Pflugers Archiv : European journal of physiology 20080201
Title: Mechanism of angiotensin II-induced superoxide production in cells reconstituted with angiotensin type 1 receptor and the components of NADPH oxidase.
Journal: The Journal of biological chemistry 20080104
Title: EGF-like peptides mediate FSH-induced maturation of cumulus cell-enclosed mouse oocytes.
Journal: Molecular reproduction and development 20080101
Title: Angiotensin II activates extracellular signal-regulated kinase independently of receptor tyrosine kinases in renal smooth muscle cells: implications for blood pressure regulation.
Journal: The Journal of pharmacology and experimental therapeutics 20080101
Title: Biochemical assay-based selectivity profiling of clinically relevant kinase inhibitors on mutant forms of EGF receptor.
Journal: Journal of receptor and signal transduction research 20080101
Title: HER2 oncogenic function escapes EGFR tyrosine kinase inhibitors via activation of alternative HER receptors in breast cancer cells.
Journal: PloS one 20080101
Title: A role for SNX5 in the regulation of macropinocytosis.
Journal: BMC cell biology 20080101
Title: Role of elevated EGFR phosphorylation in the induction of structural remodelling and altered mechanical properties of resistance artery from type 2 diabetic mice.
Journal: Diabetes/metabolism research and reviews 20080101
Title: Leptin stimulates the proliferation of human oesophageal adenocarcinoma cells via HB-EGF and Tgfalpha mediated transactivation of the epidermal growth factor receptor.
Journal: British journal of biomedical science 20080101
Title: EGFR plays a pivotal role in the regulation of polyamine-dependent apoptosis in intestinal epithelial cells.
Journal: Cellular signalling 20071201
Title: Leptin stimulates endothelin-1 expression via extracellular signal-regulated kinase by epidermal growth factor receptor transactivation in rat aortic smooth muscle cells.
Journal: European journal of pharmacology 20071114
Title: Lysophosphatidylcholine stimulates EGF receptor activation and mesangial cell proliferation: regulatory role of Src and PKC.
Journal: Biochimica et biophysica acta 20071101
Title: Involvement of KATP and KvLQT1 K+ channels in EGF-stimulated alveolar epithelial cell repair processes.
Journal: American journal of physiology. Lung cellular and molecular physiology 20071001
Title: Heparin-binding EGF-like growth factor mediates oxyhemoglobin-induced suppression of voltage-dependent potassium channels in rabbit cerebral artery myocytes.
Journal: American journal of physiology. Heart and circulatory physiology 20070901
Title: Epidermal growth factor receptor signaling modulates apoptosis via p38alpha MAPK-dependent activation of Bax in intestinal epithelial cells.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20070901
Title: Protease activated receptor 2 and epidermal growth factor receptor are involved in the regulation of human sperm motility.
Journal: Asian journal of andrology 20070901
Title: Activation of NADPH oxidase by transforming growth factor-beta in hepatocytes mediates up-regulation of epidermal growth factor receptor ligands through a nuclear factor-kappaB-dependent mechanism.
Journal: The Biochemical journal 20070715
Title: Dynamic and differential regulation of NKCC1 by calcium and cAMP in the native human colonic epithelium.
Journal: The Journal of physiology 20070715
Title: Epiregulin promotes proliferation and migration of renal proximal tubular cells.
Journal: American journal of physiology. Renal physiology 20070701
Title: Lutropin/choriogonadotropin stimulate the proliferation of primary cultures of rat Leydig cells through a pathway that involves activation of the extracellularly regulated kinase 1/2 cascade.
Journal: Endocrinology 20070701
Title: Depolarization-induced, glutamate receptor-mediated, and transactivation-dependent extracellular-signal regulated kinase phosphorylation in cultured cerebellar granule neurons.
Journal: Neuroscience 20070629
Title: Upregulation of retinoic acid receptor-beta by the epidermal growth factor-receptor inhibitor PD153035 is not mediated by blockade of ErbB pathways.
Journal: Journal of cellular physiology 20070601
Title: The neuregulin-1 receptor erbB4 controls glutamatergic synapse maturation and plasticity.
Journal: Neuron 20070524
Title: Arsenite and insulin exhibit opposing effects on epidermal growth factor receptor and keratinocyte proliferative potential.
Journal: Toxicology and applied pharmacology 20070515
Title: ERK-dependent and -independent pathways trigger human neural progenitor cell migration.
Journal: Toxicology and applied pharmacology 20070515
Title: Inhibition of ADAM17 reduces hypoxia-induced brain tumor cell invasiveness.
Journal: Cancer science 20070501
Title: The control of tissue architecture over nuclear organization is crucial for epithelial cell fate.
Journal: Journal of cell science 20070501
Title: Activation of mitogen-activated protein kinase by hepatocyte growth factor is stimulated by both alpha1- and beta2-adrenergic agonists in primary cultures of adult rat hepatocytes.
Journal: Journal of pharmacological sciences 20070401
Title: Niflumic acid and AG-1478 reduce cigarette smoke-induced mucin synthesis: the role of hCLCA1.
Journal: Chest 20070401
Title: Nicotine-induced vascular endothelial growth factor release via the EGFR-ERK pathway in rat vascular smooth muscle cells.
Journal: Life sciences 20070320
Title: EGFR-activated signaling and actin remodeling regulate cyclic stretch-induced NRF2-ARE activation.
Journal: American journal of respiratory cell and molecular biology 20070301
Title: Extracellular signal-regulated kinase activation by parathyroid hormone in distal tubule cells.
Journal: American journal of physiology. Renal physiology 20070301
Title: The epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor AG1478 increases the formation of inactive untethered EGFR dimers. Implications for combination therapy with monoclonal antibody 806.
Journal: The Journal of biological chemistry 20070202
Title: Signaling of mitochondrial biogenesis following oxidant injury.
Journal: The Journal of biological chemistry 20070126
Title: Skeletal muscle stem cells express anti-apoptotic ErbB receptors during activation from quiescence.
Journal: Experimental cell research 20070115
Title: Histone deacetylase inhibitors in combinations: will the preclinical promises be kept?
Journal: Cancer journal (Sudbury, Mass.) 20070101
Title: Apoptosis induced by depsipeptide FK228 coincides with inhibition of survival signaling in lung cancer cells.
Journal: Cancer journal (Sudbury, Mass.) 20070101
Title: Histamine stimulation of MMP-1(collagenase-1) secretion and gene expression in gastric epithelial cells: role of EGFR transactivation and the MAP kinase pathway.
Journal: The international journal of biochemistry & cell biology 20070101
Title: Aldosterone rapidly activates protein kinase D via a mineralocorticoid receptor/EGFR trans-activation pathway in the M1 kidney CCD cell line.
Journal: The Journal of steroid biochemistry and molecular biology 20070101
Title: Maximal beta3-adrenergic regulation of lipolysis involves Src and epidermal growth factor receptor-dependent ERK1/2 activation.
Journal: The Journal of biological chemistry 20061208
Title: Differentiated thyroid cancer cell invasion is regulated through epidermal growth factor receptor-dependent activation of matrix metalloproteinase (MMP)-2/gelatinase A.
Journal: Endocrine-related cancer 20061201
Title: EGFRvIII undergoes activation-dependent downregulation mediated by the Cbl proteins.
Journal: Oncogene 20061019
Title: GnRH actions on rat preovulatory follicles are mediated by paracrine EGF-like factors.
Journal: Molecular reproduction and development 20061001
Title: Treatment of HNSCC cell lines with the EGFR-specific inhibitor cetuximab (Erbitux) results in paradox phosphorylation of tyrosine 1173 in the receptor.
Journal: FEBS letters 20060904
Title: Gefitinib prevents bleomycin-induced lung fibrosis in mice.
Journal: American journal of respiratory and critical care medicine 20060901
Title: Effects of benzo-a-pyrene on oxytocin-induced Ca2+ oscillations in myometrial cells.
Journal: Toxicology letters 20060820
Title: Role of epidermal growth factor receptor transactivation in alpha1B-adrenoceptor phosphorylation.
Journal: European journal of pharmacology 20060807
Title: STAT3 attenuates EGFR-mediated ERK activation and cell survival during oxidant stress in mouse proximal tubular cells.
Journal: Kidney international 20060801
Title: Peroxisome proliferator-activated receptor-gamma inhibits cigarette smoke solution-induced mucin production in human airway epithelial (NCI-H292) cells.
Journal: American journal of physiology. Lung cellular and molecular physiology 20060701
Title: Activation of the lutropin/choriogonadotropin receptor in MA-10 cells stimulates tyrosine kinase cascades that activate ras and the extracellular signal regulated kinases (ERK1/2).
Journal: Endocrinology 20060701
Title: Leuprorelin acetate affects ERK1/2 activity in prostate cancer cells.
Journal: International journal of oncology 20060701
Title: [Involvement of epidermal growth factor receptor signaling pathway in tamoxifen resistance of MCF-7 cells].
Journal: Ai zheng = Aizheng = Chinese journal of cancer 20060701
Title: Activation of insulin-like growth factor type-1 receptor is required for H2O2-induced PKB phosphorylation in vascular smooth muscle cells.
Journal: Canadian journal of physiology and pharmacology 20060701
Title: Metalloprotease-dependent amphiregulin release mediates tumor necrosis factor-alpha-induced IL-8 secretion in the human airway epithelial cell line NCI-H292.
Journal: Life sciences 20060522
Title: Preclinical analysis of the analinoquinazoline AG1478, a specific small molecule inhibitor of EGF receptor tyrosine kinase.
Journal: Biochemical pharmacology 20060514
Title: Lysophosphatidic acid-induced effects in human colon carcinoma DLD1 cells are partially dependent on transactivation of epidermal growth factor receptor.
Journal: The Journal of surgical research 20060501
Title: Galphaq expression activates EGFR and induces Akt mediated cardiomyocyte survival: dissociation from Galphaq mediated hypertrophy.
Journal: Journal of molecular and cellular cardiology 20060501
Title: Arachidonic acid induces ERK activation via Src SH2 domain association with the epidermal growth factor receptor.
Journal: Kidney international 20060501
Title: Transcription levels of invasion-related genes in prostate cancer cells are modified by inhibitors of tyrosine kinase.
Journal: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20060501
Title: HER2 expression as a potential marker for response to therapy targeted to the EGFR.
Journal: British journal of cancer 20060424
Title: Vascular responses to alpha1-adrenergic receptors in small rat mesenteric arteries depend on mitochondrial reactive oxygen species.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20060401
Title: PAR-type thrombin receptors in renal carcinoma cells: PAR1-mediated EGFR activation promotes cell migration.
Journal: Oncology reports 20060401
Title: Urokinase plasminogen activator receptor (uPAR) expression is reduced by tyrosine kinase inhibitors.
Journal: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20060401
Title: Src tyrosine kinase inhibitor PP2 suppresses ERK1/2 activation and epidermal growth factor receptor transactivation by X-irradiation.
Journal: Biochemical and biophysical research communications 20060310
Title: A novel mechanism for integrin-mediated ras activation in breast carcinoma cells: the alpha6beta4 integrin regulates ErbB2 translation and transactivates epidermal growth factor receptor/ErbB2 signaling.
Journal: Cancer research 20060301
Title: Tyrosine kinase inhibitors alter adhesivity of prostatic cancer cells to extracellular matrix components.
Journal: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20060301
Title: Deficient E-cadherin adhesion in C57BL/6J-Min/+ mice is associated with increased tyrosine kinase activity and RhoA-dependent actomyosin contractility.
Journal: Experimental cell research 20060215
Title: Tyrphostin-A47 inhibitable tyrosine phosphorylation of flagellar proteins is associated with distinct alteration of motility pattern in hamster spermatozoa.
Journal: Molecular reproduction and development 20060201
Title: Inhibition of autophosphorylation of epidermal growth factor receptor by small peptides in vitro.
Journal: British journal of pharmacology 20060201
Title: Inhibition of epidermal growth factor receptor activation enhances in vivo histamine-stimulated gastric acid secretion in the rat.
Journal: Digestive diseases and sciences 20060201
Title: Selective induction of cyclooxygenase-2 plays a role in lysophosphatidic acid regulated Fas ligand cell surface presentation.
Journal: FEBS letters 20060123
Title: Role of EGF receptor transactivation in phosphoinositide 3-kinase-dependent activation of MAP kinase by GPCRs.
Journal: Journal of cellular physiology 20060101
Title: Blockade of EGFR and ErbB2 by the novel dual EGFR and ErbB2 tyrosine kinase inhibitor GW572016 sensitizes human colon carcinoma GEO cells to apoptosis.
Journal: Cancer research 20060101
Title: The invasive behaviour of prostatic cancer cells is suppressed by inhibitors of tyrosine kinase.
Journal: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20060101
Title: Aldosterone stimulates activity and surface expression of NHE3 in human primary proximal tubule epithelial cells (RPTEC).
Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20060101
Title: Concomitant cell growth and differentiation are dependent on erbB1 and integrin activation in an autonomously surviving colon adenocarcinoma: involvement of autocrine amphiregulin secretion.
Journal: Anticancer research 20060101
Title: [Oxidized glutathione induces activation of the epidermal growth factor receptor and MAP kinases ERK 1,2].
Journal: Tsitologiia 20060101
Title: Toluene diisocyanate (TDI) induces production of inflammatory cytokines and chemokines by bronchial epithelial cells via the epidermal growth factor receptor and p38 mitogen-activated protein kinase pathways.
Journal: Experimental lung research 20060101
Title: Signal transduction through substance P receptor in human glioblastoma cells: roles for Src and PKCdelta.
Journal: Cancer chemotherapy and pharmacology 20051201
Title: Anilinodialkoxyquinazolines: screening epidermal growth factor receptor tyrosine kinase inhibitors for potential tumor imaging probes.
Journal: Journal of medicinal chemistry 20051117
Title: PTPase inhibition restores ERK1/2 phosphorylation and protects mammary epithelial cells from apoptosis.
Journal: Biochemical and biophysical research communications 20051104
Title: Helicobacter pylori-stimulated interleukin-8 (IL-8) promotes cell proliferation through transactivation of epidermal growth factor receptor (EGFR) by disintegrin and metalloproteinase (ADAM) activation.
Journal: Digestive diseases and sciences 20051101
Title: Transactivation of epidermal growth factor receptor is involved in leptin-induced activation of janus-activated kinase 2 and extracellular signal-regulated kinase 1/2 in human gastric cancer cells.
Journal: Cancer research 20051015
Title: EGFR activation mediates inhibition of axon regeneration by myelin and chondroitin sulfate proteoglycans.
Journal: Science (New York, N.Y.) 20051007
Title: Cytokine-induced endothelial arginase expression is dependent on epidermal growth factor receptor.
Journal: American journal of respiratory cell and molecular biology 20051001
Title: Air pollution particles activate NF-kappaB on contact with airway epithelial cell surfaces.
Journal: Toxicology and applied pharmacology 20051001
Title: Enhanced efficacy of radioimmunotherapy with 90Y-CHX-A''-DTPA-hu3S193 by inhibition of epidermal growth factor receptor (EGFR) signaling with EGFR tyrosine kinase inhibitor AG1478.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20051001
Title: beta-Arrestin 2 expression determines the transcriptional response to lysophosphatidic acid stimulation in murine embryo fibroblasts.
Journal: The Journal of biological chemistry 20050916
Title: Correlation of translocation of tight junction protein Zonula occludens-1 and activation of epidermal growth factor receptor in the regulation of invasion of pancreatic cancer cells.
Journal: International journal of oncology 20050901
Title: EGF-induced EGF-receptor and MAP kinase phosphorylation in goat cumulus cells during in vitro maturation.
Journal: Molecular reproduction and development 20050801
Title: Epidermal growth factor receptor blockade mediates smooth muscle cell apoptosis and improves survival in rats with pulmonary hypertension.
Journal: Circulation 20050719
Title: Fluorescence and analytical ultracentrifugation analyses of the interaction of the tyrosine kinase inhibitor, tyrphostin AG 1478-mesylate, with albumin.
Journal: Analytical biochemistry 20050715
Title: Plasminogen activator inhibitor type-1 gene expression and induced migration in TGF-beta1-stimulated smooth muscle cells is pp60(c-src)/MEK-dependent.
Journal: Journal of cellular physiology 20050701
Title: Epidermal growth factor receptor tyrosine kinase-mediated signalling contributes to diabetes-induced vascular dysfunction in the mesenteric bed.
Journal: British journal of pharmacology 20050701
Title: A FRET-based probe for epidermal growth factor receptor bound non-covalently to a pair of synthetic amphipathic helixes.
Journal: Experimental cell research 20050701
Title: Activation of the epidermal growth factor receptor in optic nerve astrocytes leads to early and transient induction of cyclooxygenase-2.
Journal: Investigative ophthalmology & visual science 20050601
Title: Studies of tyrosine phosphorylation and Src family tyrosine kinases in the lens epithelium.
Journal: Investigative ophthalmology & visual science 20050601
Title: PGE2 up-regulates vascular endothelial growth factor expression in MKN28 gastric cancer cells via epidermal growth factor receptor signaling system.
Journal: Experimental oncology 20050601
Title: Dopamine D2 receptor stimulation of mitogen-activated protein kinases mediated by cell type-dependent transactivation of receptor tyrosine kinases.
Journal: Journal of neurochemistry 20050501
Title: Dominant-negative Notch3 receptor inhibits mitogen-activated protein kinase pathway and the growth of human lung cancers.
Journal: Cancer research 20050501
Title: Differential sensitivities of trastuzumab (Herceptin)-resistant human breast cancer cells to phosphoinositide-3 kinase (PI-3K) and epidermal growth factor receptor (EGFR) kinase inhibitors.
Journal: Breast cancer research and treatment 20050501
Title: Profiling EGFR activity in head and neck squamous cell carcinoma by using a novel layered membrane Western blot technology.
Journal: Oral oncology 20050501
Title: Inhibitors of tyrosine kinase inhibit the production of urokinase plasminogen activator in human prostatic cancer cells.
Journal: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20050501
Title: The role of tyrosine kinase-mediated pathways in diabetes-induced alterations in responsiveness of rat carotid artery.
Journal: Autonomic & autacoid pharmacology 20050401
Title: Epidermal growth factor receptor-dependent and -independent pathways in hydrogen peroxide-induced mitogen-activated protein kinase activation in cardiomyocytes and heart fibroblasts.
Journal: The Journal of pharmacology and experimental therapeutics 20050301
Title: Amphiregulin acts as an autocrine survival factor for adult sensory neurons.
Journal: Neuroreport 20050227
Title: Growth of intestinal epithelium in organ culture is dependent on EGF signalling.
Journal: Experimental cell research 20050215
Title: Protein kinase C zeta is required for epidermal growth factor-induced chemotaxis of human breast cancer cells.
Journal: Cancer research 20050215
Title: Mechanical stretch stimulates protein kinase B/Akt phosphorylation in epidermal cells via angiotensin II type 1 receptor and epidermal growth factor receptor.
Journal: The Journal of biological chemistry 20050128
Title: Novel use of zebrafish as a vertebrate model to screen radiation protectors and sensitizers.
Journal: International journal of radiation oncology, biology, physics 20050101
Title: [Effect of tyrosine kinase inhibitors on airway remodeling in bronchial asthma].
Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20050101
Title: Combining RNA interference and kinase inhibitors against cell signalling components involved in cancer.
Journal: BMC cancer 20050101
Title: The effects of S-phase kinase-associated protein 2 (SKP2) on cell cycle status, viability, and chemoresistance in A549 lung adenocarcinoma cells.
Journal: Experimental lung research 20041201
Title: Transactivation of epidermal growth factor receptor mediates catecholamine-induced growth of vascular smooth muscle.
Journal: Circulation research 20041112
Title: Evidence that basal activity, but not transactivation, of the epidermal growth factor receptor tyrosine kinase is required for insulin-like growth factor I-induced activation of extracellular signal-regulated kinase in oral carcinoma cells.
Journal: Endocrinology 20041101
Title: Ectodomain shedding-dependent transactivation of epidermal growth factor receptors in response to insulin-like growth factor type I.
Journal: Molecular endocrinology (Baltimore, Md.) 20041101
Title: Enhanced epidermal growth factor receptor activation in human cholangiocarcinoma cells.
Journal: Journal of hepatology 20041101
Title: Endothelin-1 stimulates cyclooxygenase-2 expression in ovarian cancer cells through multiple signaling pathways: evidence for involvement of transactivation of the epidermal growth factor receptor.
Journal: Journal of cardiovascular pharmacology 20041101
Title: Effects of a conditionally active v-ErbB and an EGF-R inhibitor on transformation of NIH-3T3 cells and abrogation of cytokine dependency of hematopoietic cells.
Journal: Oncogene 20041014
Title: Clustering of cellular prion protein induces ERK1/2 and stathmin phosphorylation in GT1-7 neuronal cells.
Journal: FEBS letters 20041008
Title: Autocrine regulation of steroidogenic function of Leydig cells by transforming growth factor-alpha.
Journal: Molecular and cellular endocrinology 20040930
Title: Activation of epidermal growth factor receptors directs astrocytes to organize in a network surrounding axons in the developing rat optic nerve.
Journal: Developmental biology 20040915
Title: Interactions of EGFR and caveolin-1 in human glioblastoma cells: evidence that tyrosine phosphorylation regulates EGFR association with caveolae.
Journal: Oncogene 20040909
Title: The AG1478 tyrosine kinase inhibitor is an effective suppressor of leiomyoma cell growth.
Journal: Human reproduction (Oxford, England) 20040901
Title: Mechanisms of vascular angiotensin II surface receptor regulation by epidermal growth factor.
Journal: Journal of cellular physiology 20040901
Title: L-Glutamine ameliorates acetaldehyde-induced increase in paracellular permeability in Caco-2 cell monolayer.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20040901
Title: Simultaneously targeting epidermal growth factor receptor tyrosine kinase and cyclooxygenase-2, an efficient approach to inhibition of squamous cell carcinoma of the head and neck.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20040901
Title: Activation of epidermal growth factor receptor via CCR3 in bronchial epithelial cells.
Journal: Biochemical and biophysical research communications 20040723
Title: Extracellular calcium-sensing receptor transactivates the epidermal growth factor receptor by a triple-membrane-spanning signaling mechanism.
Journal: Biochemical and biophysical research communications 20040723
Title: The epidermal growth factor receptor (EGFR) and proline rich tyrosine kinase 2 (PYK2) are involved in tissue factor dependent factor VIIa signalling in HaCaT cells.
Journal: Thrombosis and haemostasis 20040701
Title: Insulin reduces the requirement for EGFR transactivation in bombesin-induced DNA synthesis.
Journal: Biochemical and biophysical research communications 20040611
Title: Epidermal growth factor differentially augments G(i)-mediated stimulation of c-Jun N-terminal kinase activity.
Journal: British journal of pharmacology 20040601
Title: Protease-activated receptor 2 in colon cancer: trypsin-induced MAPK phosphorylation and cell proliferation are mediated by epidermal growth factor receptor transactivation.
Journal: The Journal of biological chemistry 20040514
Title: Sphingosine 1-phosphate transactivates the platelet-derived growth factor beta receptor and epidermal growth factor receptor in vascular smooth muscle cells.
Journal: Circulation research 20040430
Title: gp91phox-containing NADPH oxidase mediates endothelial dysfunction in renovascular hypertension.
Journal: Circulation 20040413
Title: Human airway trypsin-like protease increases mucin gene expression in airway epithelial cells.
Journal: American journal of respiratory cell and molecular biology 20040401
Title: Combined inhibition of epidermal growth factor receptor and JAK/STAT pathways results in greater growth inhibition in vitro than single agent therapy.
Journal: Molecular cancer therapeutics 20040401
Title: Inhibition of epidermal growth factor receptor signaling protects human malignant glioma cells from hypoxia-induced cell death.
Journal: Cancer research 20040301
Title: Gs protein-coupled receptor agonists induce transactivation of the epidermal growth factor receptor in T84 cells: implications for epithelial secretory responses.
Journal: The Journal of biological chemistry 20040220
Title: Selective inhibition of survival signal transduction pathways enhanced radiosensitivity in human esophageal cancer cell lines in vitro.
Journal: Anticancer research 20040101
Title: Biglycan is internalized via a chlorpromazine-sensitive route.
Journal: Cellular & molecular biology letters 20040101
Title: Angiotensin II regulation of TGF-beta in murine mesangial cells involves both PI3 kinase and MAP kinase.
Journal: Annals of clinical and laboratory science 20040101
Title: Epidermal growth factor induction of phenotype-dependent cell cycle arrest in vascular smooth muscle cells is through the mitogen-activated protein kinase pathway.
Journal: The Journal of biological chemistry 20031226
Title: Antagonism of rat beta-cell voltage-dependent K+ currents by exendin 4 requires dual activation of the cAMP/protein kinase A and phosphatidylinositol 3-kinase signaling pathways.
Journal: The Journal of biological chemistry 20031226
Title: Cell surface receptors activate p21-activated kinase 1 via multiple Ras and PI3-kinase-dependent pathways.
Journal: Cellular signalling 20031201
Title: Transactivation of the epidermal growth factor receptor mediates cholinergic agonist-induced proliferation of H508 human colon cancer cells.
Journal: Cancer research 20031015
Title: Leukotrienes mediate part of Ova-induced lung effects in mice via EGFR.
Journal: American journal of physiology. Lung cellular and molecular physiology 20031001
Title: Cross-talk between the receptor tyrosine kinases Ron and epidermal growth factor receptor.
Journal: Experimental cell research 20031001
Title: Expression of ErbB receptors in ES cell-derived cardiomyocytes.
Journal: Biochemical and biophysical research communications 20030912
Title: EGF receptor mediates adhesion-dependent activation of the Rac GTPase: a role for phosphatidylinositol 3-kinase and Vav2.
Journal: Oncogene 20030904
Title: Activation of ERK1/2 by platelet-activating factor receptor is independent of receptor internalisation and G-protein activation.
Journal: Cellular signalling 20030901
Title: Epidermal growth factor receptor regulates normal urothelial regeneration.
Journal: Laboratory investigation; a journal of technical methods and pathology 20030901
Title: Activated epidermal growth factor receptor (ErbB1) protects the heart against stress-induced injury in mice.
Journal: American journal of physiology. Regulatory, integrative and comparative physiology 20030801
Title: Transactivation of the epidermal growth factor receptor mediates parathyroid hormone and prostaglandin F2 alpha-stimulated mitogen-activated protein kinase activation in cultured transgenic murine osteoblasts.
Journal: Molecular endocrinology (Baltimore, Md.) 20030801
Title: Alpha-adrenergic stimulation of ERK phosphorylation in astrocytes is alpha(2)-specific and may be mediated by transactivation.
Journal: Brain research 20030718
Title: Inhibition of zebrafish epidermal growth factor receptor activity results in cardiovascular defects.
Journal: Mechanisms of development 20030701
Title: Activation of mitogen-activated protein kinase by cholinergic agonists and EGF in human compared with rat cultured conjunctival goblet cells.
Journal: Investigative ophthalmology & visual science 20030601
Title: Inhibitors that target protein kinases for the treatment of ovarian carcinoma.
Journal: American journal of obstetrics and gynecology 20030501
Title: Cytochrome P450 2C9-derived epoxyeicosatrienoic acids induce angiogenesis via cross-talk with the epidermal growth factor receptor (EGFR).
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030401
Title: Dissociation of focal adhesion kinase and paxillin tyrosine phosphorylation induced by bombesin and lysophosphatidic acid from epidermal growth factor receptor transactivation in Swiss 3T3 cells.
Journal: Journal of cellular physiology 20030301
Title: Signal transduction pathways used by EGF to stimulate protein secretion in rat lacrimal gland.
Journal: Investigative ophthalmology & visual science 20030301
Title: P2Y receptor-mediated stimulation of Müller glial cell DNA synthesis: dependence on EGF and PDGF receptor transactivation.
Journal: Investigative ophthalmology & visual science 20030301
Title: Epidermal growth factor receptor trans-activation mediates the tonic and fibrogenic effects of endothelin in the aortic wall of transgenic mice.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030201
Title: Relationship of EGFR signal-transduction modulation by tyrosine kinase inhibitors to chemosensitivity and programmed cell death in lung cancer cell lines.
Journal: Methods in molecular medicine 20030101
Title: Phosphorylation and subcellular distribution of connexin43 in normal and stressed cells.
Journal: Cell and tissue research 20030101
Title: [Effect of EGF on the intracellular distribution of heat-shock proteins in A431 cells].
Journal: Tsitologiia 20030101
Title: Cholesterol depletion from the plasma membrane triggers ligand-independent activation of the epidermal growth factor receptor.
Journal: The Journal of biological chemistry 20021220
Title: Internalization of inactive EGF receptor into endosomes and the subsequent activation of endosome-associated EGF receptors. Epidermal growth factor.
Journal: Science's STKE : signal transduction knowledge environment 20021203
Title: ACh and adenosine activate PI3-kinase in rabbit hearts through transactivation of receptor tyrosine kinases.
Journal: American journal of physiology. Heart and circulatory physiology 20021201
Title: Oxidative stress induces arachidonate release from human lung cells through the epithelial growth factor receptor pathway.
Journal: American journal of respiratory cell and molecular biology 20021201
Title: Lyn- and ERK-mediated vs. Ca2+ -mediated neutrophil O responses with thermal injury.
Journal: American journal of physiology. Cell physiology 20021101
Title: Activation of extracellular-regulated kinase by 5-hydroxytryptamine(2A) receptors in PC12 cells is protein kinase C-independent and requires calmodulin and tyrosine kinases.
Journal: The Journal of pharmacology and experimental therapeutics 20021101
Title: Angiotensin II triggers EGFR tyrosine kinase-dependent Ca2+ influx in afferent arterioles.
Journal: Hypertension (Dallas, Tex. : 1979) 20021101
Title: Activation of mitogen-activated protein kinase pathway by the antiandrogen hydroxyflutamide in androgen receptor-negative prostate cancer cells.
Journal: Cancer research 20021101
Title: Lysophosphatidic acid-induced squamous cell carcinoma cell proliferation and motility involves epidermal growth factor receptor signal transactivation.
Journal: Cancer research 20021101
Title: 4-Hydroxy-2-nonenal enhances fibronectin production by IMR-90 human lung fibroblasts partly via activation of epidermal growth factor receptor-linked extracellular signal-regulated kinase p44/42 pathway.
Journal: Toxicology and applied pharmacology 20021101
Title: Secretin regulates paracellular permeability in canine gastric monolayers by a Src kinase-dependent pathway.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20021001
Title: Interferon-gamma activates EGF receptor and increases TGF-alpha in T84 cells: implications for chloride secretion.
Journal: American journal of physiology. Gastrointestinal and liver physiology 20021001
Title: Tyrosine kinases regulate intracellular calcium during alpha(2)-adrenergic contraction in rat aorta.
Journal: American journal of physiology. Heart and circulatory physiology 20021001
Title: Antagonistic and agonistic effects of quinazoline tyrosine kinase inhibitors on mutant EGF receptor function.
Journal: International journal of cancer 20020910
Title: Beta-adrenergic receptor-mediated DNA synthesis in cardiac fibroblasts is dependent on transactivation of the epidermal growth factor receptor and subsequent activation of extracellular signal-regulated kinases.
Journal: The Journal of biological chemistry 20020830
Title: Mutant epidermal growth factor receptor up-regulates molecular effectors of tumor invasion.
Journal: Cancer research 20020615
Title: Direct inhibition of the cloned Kv1.5 channel by AG-1478, a tyrosine kinase inhibitor.
Journal: American journal of physiology. Cell physiology 20020601
Title: Inhibitory effect and its kinetic analysis of tyrphostin AG1478 on recombinant human protein kinase CK2 holoenzyme.
Journal: Acta pharmacologica Sinica 20020601
Title: Vitamin D inhibits the activation of stress-activated protein kinases by physiological and environmental stresses in keratinocytes.
Journal: The Journal of endocrinology 20020601
Title: EGFR is a transducer of the urokinase receptor initiated signal that is required for in vivo growth of a human carcinoma.
Journal: Cancer cell 20020601
Title: alpha 2B-adrenergic receptor activates MAPK via a pathway involving arachidonic acid metabolism, matrix metalloproteinases, and epidermal growth factor receptor transactivation.
Journal: The Journal of biological chemistry 20020531
Title: Role of calmodulin in the modulation of the MAPK signalling pathway and the transactivation of epidermal growth factor receptor mediated by PKC.
Journal: FEBS letters 20020424
Title: Independence of angiotensin II-induced MAP kinase activation from angiotensin type 1 receptor internalization in clone 9 hepatocytes.
Journal: Molecular endocrinology (Baltimore, Md.) 20020301
Title: Prostaglandin E2 transactivates EGF receptor: a novel mechanism for promoting colon cancer growth and gastrointestinal hypertrophy.
Journal: Nature medicine 20020301
Title: Hydrogen peroxide activates endothelial nitric-oxide synthase through coordinated phosphorylation and dephosphorylation via a phosphoinositide 3-kinase-dependent signaling pathway.
Journal: The Journal of biological chemistry 20020222
Title: Regulation of sarcolemmal Na(+)/H(+) exchange by hydrogen peroxide in adult rat ventricular myocytes.
Journal: Cardiovascular research 20020201
Title: TGF-alpha-driven tumor growth is inhibited by an EGF receptor tyrosine kinase inhibitor.
Journal: Biochemical and biophysical research communications 20020111
Title: CD95-mediated apoptosis of human glioma cells: modulation by epidermal growth factor receptor activity.
Journal: Brain pathology (Zurich, Switzerland) 20020101
Title: Insulin-like growth factor receptor I mediates resistance to anti-epidermal growth factor receptor therapy in primary human glioblastoma cells through continued activation of phosphoinositide 3-kinase signaling.
Journal: Cancer research 20020101
Title: Metabotropic glutamate receptor 5-induced phosphorylation of extracellular signal-regulated kinase in astrocytes depends on transactivation of the epidermal growth factor receptor.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20011215
Title: Transactivation of the epidermal growth factor receptor is involved in 12-O-tetradecanoylphorbol-13-acetate-induced signal transduction.
Journal: The Journal of biological chemistry 20011214
Title: Induction of EGFR-dependent and EGFR-independent signaling pathways by ultraviolet A irradiation.
Journal: DNA and cell biology 20011201
Title: Potassium channel blocker activates extracellular signal-regulated kinases through Pyk2 and epidermal growth factor receptor in rat cardiomyocytes.
Journal: Journal of the American College of Cardiology 20011101
Title: EGF receptor function is required in late G(1) for cell cycle progression induced by bombesin and bradykinin.
Journal: American journal of physiology. Cell physiology 20010901
Title: Human glioblastoma xenografts overexpressing a tumor-specific mutant epidermal growth factor receptor sensitized to cisplatin by the AG1478 tyrosine kinase inhibitor.
Journal: Journal of neurosurgery 20010901
Title: Activation of the EGF receptor signaling pathway in airway epithelial cells exposed to Utah Valley PM.
Journal: American journal of physiology. Lung cellular and molecular physiology 20010801
Title: Further evidence for the involvement of insulin receptor substrates in epidermal growth factor-induced activation of phosphatidylinositol 3-kinase.
Journal: European journal of biochemistry 20010801
Title: Extremely low-dose ionizing radiation causes activation of mitogen-activated protein kinase pathway and enhances proliferation of normal human diploid cells.
Journal: Cancer research 20010715
Title: Gi-mediated activation of the Syk kinase by the receptor mimetic basic secretagogues of mast cells: role in mediating arachidonic acid/metabolites release.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20010701
Title: Integrins mediate functional pre- and postsynaptic maturation at a hippocampal synapse.
Journal: Nature 20010517
Title: c-Jun N-terminal kinase activation by hydrogen peroxide in endothelial cells involves SRC-dependent epidermal growth factor receptor transactivation.
Journal: The Journal of biological chemistry 20010511
Title: Prevention of apoptosis by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in the MCF-10A cell line: correlation with increased transforming growth factor alpha production.
Journal: Cancer research 20010415
Title: High-performance liquid chromatographic analysis of the tyrphostin AG1478, a specific inhibitor of the epidermal growth factor receptor tyrosine kinase, in mouse plasma.
Journal: Journal of chromatography. B, Biomedical sciences and applications 20010415
Title: Pancreatic cancer cells require an EGF receptor-mediated autocrine pathway for proliferation in serum-free conditions.
Journal: British journal of cancer 20010401
Title: Thrombin-induced p38 mitogen-activated protein kinase activation is mediated by epidermal growth factor receptor transactivation pathway.
Journal: British journal of pharmacology 20010401
Title: The relative role of ErbB1-4 receptor tyrosine kinases in radiation signal transduction responses of human carcinoma cells.
Journal: Oncogene 20010315
Title: Transmodulation of epidermal growth factor receptor mediates IL-1 beta-induced MMP-1 expression in cultured human keratinocytes.
Journal: International journal of molecular medicine 20010301
Title: BIBX1382BS, but not AG1478 or PD153035, inhibits the ErbB kinases at different concentrations in intact cells.
Journal: Biochemical and biophysical research communications 20010216
Title: STAT3-mediated constitutive expression of SOCS-3 in cutaneous T-cell lymphoma.
Journal: Blood 20010215
Title: Activation of extracellular-regulated kinases by normal and mutant EGF receptors.
Journal: Biochimica et biophysica acta 20010205
Title: N-acetylcysteine inhibits angiotensin ii-mediated activation of extracellular signal-regulated kinase and epidermal growth factor receptor.
Journal: Biochemical and biophysical research communications 20010202
Title: Tyrosine kinase involvement in renal arteriolar constrictor responses to angiotensin II.
Journal: Hypertension (Dallas, Tex. : 1979) 20010201
Title: Angiotensin AT(1) and AT(2) receptors differentially regulate angiopoietin-2 and vascular endothelial growth factor expression and angiogenesis by modulating heparin binding-epidermal growth factor (EGF)-mediated EGF receptor transactivation.
Journal: Circulation research 20010119
Title: Aberrant receptor signaling in human malignant gliomas: mechanisms and therapeutic implications.
Journal: Cancer letters 20010101
Title: Signal therapy for RAS-induced cancers in combination of AG 879 and PP1, specific inhibitors for ErbB2 and Src family kinases, that block PAK activation.
Journal: Cancer journal (Sudbury, Mass.) 20010101
Title: Bojko A, et al. The effect of tyrphostins AG494 and AG1478 on the autocrine growth regulation of A549 and DU145 cells. Folia Histochem Cytobiol. 2012 Jul 5;50(2):186-95.
Title: Li W, et al. EGFR Inhibition Blocks Palmitic Acid-induced inflammation in cardiomyocytes and Prevents Hyperlipidemia-induced Cardiac Injury in Mice. Sci Rep. 2016 Apr 18;6:24580.
Title: Akhtar S, et al. Cationic Polyamidoamine Dendrimers as Modulators of EGFR Signaling In Vitro and In Vivo. PLoS One. 2015 Jul 13;10(7):e0132215.
Title: Dorobantu CM, et al. Tyrphostin AG1478 Inhibits Encephalomyocarditis Virus and Hepatitis C Virus by Targeting Phosphatidylinositol 4-Kinase IIIα. Antimicrob Agents Chemother. 2016 Sep 23;60(10):6402-6.
