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190383-13-2,MFCD02259590
Catalog No.:AA00APA2

190383-13-2 | H-SER-LEU-ILE-GLY-LYS-VAL-NH2

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
in stock  
$183.00   $128.00
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  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA00APA2
Chemical Name:
H-SER-LEU-ILE-GLY-LYS-VAL-NH2
CAS Number:
190383-13-2
Molecular Formula:
C28H54N8O7
Molecular Weight:
614.7778
MDL Number:
MFCD02259590
SMILES:
NCCCC[C@@H](C(=O)N[C@H](C(=O)N)C(C)C)NC(=O)CNC(=O)[C@H]([C@H](CC)C)NC(=O)[C@@H](NC(=O)[C@H](CO)N)CC(C)C
Properties
Computed Properties
 
Complexity:
931  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
6  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
43  
Hydrogen Bond Acceptor Count:
9  
Hydrogen Bond Donor Count:
9  
Isotope Atom Count:
0  
Rotatable Bond Count:
21  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
-0.7  

Literature

Title: Mixed exposure to bacterial lipopolysaccharide and seafood proteases augments inflammatory signalling in an airway epithelial cell model (A549).

Journal: Toxicology and industrial health 20161101

Title: Interleukin-17- and protease-activated receptor 2-mediated production of CXCL1 and CXCL8 modulated by cyclosporine A, vitamin D3 and glucocorticoids in human keratinocytes.

Journal: The Journal of dermatology 20120701

Title: Activation of PAR2 or/and TLR4 promotes SW620 cell proliferation and migration via phosphorylation of ERK1/2.

Journal: Oncology reports 20110201

Title: Activation of chloride secretion via proteinase-activated receptor 2 in a human eccrine sweat gland cell line--NCL-SG3.

Journal: Experimental dermatology 20080601

Title: Tryptase activates TGFbeta in human airway smooth muscle cells via direct proteolysis.

Journal: Biochemical and biophysical research communications 20080530

Title: Induction of inflammatory cytokine release from human umbilical vein endothelial cells by agonists of proteinase-activated receptor-2.

Journal: Clinical and experimental pharmacology & physiology 20080101

Title: Proinflammatory and proliferative responses of human proximal tubule cells to PAR-2 activation.

Journal: American journal of physiology. Renal physiology 20071101

Title: Protease-activated receptor-1 (PAR1) and PAR2 but not PAR4 mediate relaxations in lower esophageal sphincter.

Journal: Regulatory peptides 20070705

Title: Distinct roles for PAR1- and PAR2-mediated vasomotor modulation in human arterial and venous conduits.

Journal: Journal of thrombosis and haemostasis : JTH 20070101

Title: Induction of lactoferrin and IL-8 release from human neutrophils by tryptic enzymes via proteinase activated receptor-2.

Journal: Cell biology international 20060901

Title: Kanke T, et al. Binding of a highly potent protease-activated receptor-2 (PAR2) activating peptide, H2-furoyl-LIGRL-NH2, to human PAR2. Br J Pharmacol. 2005 May;145(2):255-63.

Title: Ramelli G, et al. Protease-activated receptor 2 signalling promotes dendritic cell antigen transport and T-cellactivation in vivo. Immunology. 2010 Jan;129(1):20-7.

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SDS
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Tags:190383-13-2 Molecular Formula|190383-13-2 MDL|190383-13-2 SMILES|190383-13-2 H-SER-LEU-ILE-GLY-LYS-VAL-NH2
Catalog No.: AA00APA2
190383-13-2,MFCD02259590
190383-13-2 | H-SER-LEU-ILE-GLY-LYS-VAL-NH2
Pack Size： 5mg
Purity：
in stock
$183.00 $128.00
Quantity
- +
Add to Card
Order Now
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Technical Information
Catalog Number: AA00APA2
Chemical Name: H-SER-LEU-ILE-GLY-LYS-VAL-NH2
CAS Number: 190383-13-2
Molecular Formula: C28H54N8O7
Molecular Weight: 614.7778
MDL Number: MFCD02259590
SMILES: NCCCC[C@@H](C(=O)N[C@H](C(=O)N)C(C)C)NC(=O)CNC(=O)[C@H]([C@H](CC)C)NC(=O)[C@@H](NC(=O)[C@H](CO)N)CC(C)C
Properties
Complexity: 931  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 6  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 43  
Hydrogen Bond Acceptor Count: 9  
Hydrogen Bond Donor Count: 9  
Isotope Atom Count: 0  
Rotatable Bond Count: 21  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: -0.7  
Literature fold

Title: Mixed exposure to bacterial lipopolysaccharide and seafood proteases augments inflammatory signalling in an airway epithelial cell model (A549).

Journal: Toxicology and industrial health20161101

Title: Interleukin-17- and protease-activated receptor 2-mediated production of CXCL1 and CXCL8 modulated by cyclosporine A, vitamin D3 and glucocorticoids in human keratinocytes.

Journal: The Journal of dermatology20120701

Title: Activation of PAR2 or/and TLR4 promotes SW620 cell proliferation and migration via phosphorylation of ERK1/2.

Journal: Oncology reports20110201

Title: Activation of chloride secretion via proteinase-activated receptor 2 in a human eccrine sweat gland cell line--NCL-SG3.

Journal: Experimental dermatology20080601

Title: Tryptase activates TGFbeta in human airway smooth muscle cells via direct proteolysis.

Journal: Biochemical and biophysical research communications20080530

Title: Induction of inflammatory cytokine release from human umbilical vein endothelial cells by agonists of proteinase-activated receptor-2.

Journal: Clinical and experimental pharmacology & physiology20080101

Title: Proinflammatory and proliferative responses of human proximal tubule cells to PAR-2 activation.

Journal: American journal of physiology. Renal physiology20071101

Title: Protease-activated receptor-1 (PAR1) and PAR2 but not PAR4 mediate relaxations in lower esophageal sphincter.

Journal: Regulatory peptides20070705

Title: Distinct roles for PAR1- and PAR2-mediated vasomotor modulation in human arterial and venous conduits.

Journal: Journal of thrombosis and haemostasis : JTH20070101

Title: Induction of lactoferrin and IL-8 release from human neutrophils by tryptic enzymes via proteinase activated receptor-2.

Journal: Cell biology international20060901

Title: Kanke T, et al. Binding of a highly potent protease-activated receptor-2 (PAR2) activating peptide, H2-furoyl-LIGRL-NH2, to human PAR2. Br J Pharmacol. 2005 May;145(2):255-63.

Title: Ramelli G, et al. Protease-activated receptor 2 signalling promotes dendritic cell antigen transport and T-cellactivation in vivo. Immunology. 2010 Jan;129(1):20-7.

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