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5128-44-9,MFCD00017446
Catalog No.:AA00DB7W

5128-44-9 | 7,4'-Di-O-methylapigenin

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1mg
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2mg
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5mg
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$80.00   $56.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00DB7W
Chemical Name:
7,4'-Di-O-methylapigenin
CAS Number:
5128-44-9
Molecular Formula:
C17H14O5
Molecular Weight:
298.2901
MDL Number:
MFCD00017446
SMILES:
COc1ccc(cc1)c1cc(=O)c2c(o1)cc(cc2O)OC
NSC Number:
94547
Properties
Computed Properties
 
Complexity:
438  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
22  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
3  
XLogP3:
2.4  

Downstream Synthesis Route

[1]ChemicalandPharmaceuticalBulletin,2002,vol.50,p.788-795

[2]MonatsheftefurChemie,1928,vol.49,p.85,87

[3]Patent:WO2006/128169,2006,A2.Locationinpatent:Page/Pagecolumn9

[1]ArchivderPharmazie,1936,vol.274,p.126,136,143

[1]JournalofChemicalCrystallography,2008,vol.38,p.21-25

[2]JournaloftheChemicalSociety,1914,vol.105,p.1829,1845

[3]MonatsheftefurChemie,1928,vol.49,p.85,87

[4]ArchivderPharmazie,2017,vol.350

[5]NaturalProductResearch,2018,vol.32,p.743-747

[1]JournaloftheChemicalSociety,1897,vol.71,p.812

[2]PlantaMedica,2013,vol.79,p.1313-1318

Literature

Title: The roles of a flavone-6-hydroxylase and 7-O-demethylation in the flavone biosynthetic network of sweet basil.

Journal: The Journal of biological chemistry 20130118

Title: [Chemical constituents contained in Aeschynanthus moningeriae].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20120701

Title: A new triterpene from Salvia xanthocheila Boiss.

Journal: Natural product research 20120101

Title: A new highly hydroxylated triterpene from Salvia atropatana Bunge.

Journal: Natural product research 20120101

Title: [Constituents from the leaves of Aquilaria sinensis].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20120101

Title: Flavonoids inhibit angiogenic cytokine production by human glioma cells.

Journal: Phytotherapy research : PTR 20110601

Title: Chemical composition of Argentinean propolis collected in extreme regions and its relation with antimicrobial and antioxidant activities.

Journal: Natural product communications 20110601

Title: Structural requirements of flavonoids for the adipogenesis of 3T3-L1 cells.

Journal: Bioorganic & medicinal chemistry 20110501

Title: [Aromatic constituents of Heteroplexis micocephal and their bioactivities].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110101

Title: The effect of 'Teucrium polium L.' extracts on insulin release from in situ isolated perfused rat pancreas in a newly modified isolation method: the role of Ca2+ and K+ channels.

Journal: Iranian biomedical journal 20101001

Title: New furanoflavanoids, intestinal alpha-glucosidase inhibitory and free-radical (DPPH) scavenging, activity from antihyperglycemic root extract of Derris indica (Lam.).

Journal: Bioorganic & medicinal chemistry 20090715

Title: Sesquiterpenoids from Teucrium ramosissimum.

Journal: Phytochemistry 20090101

Title: The use of natural product scaffolds as leads in the search for trypanothione reductase inhibitors.

Journal: Bioorganic & medicinal chemistry 20080715

Title: Anticomplementary principles of a Chinese multiherb remedy for the treatment and prevention of SARS.

Journal: Journal of ethnopharmacology 20080508

Title: Anti-allergic activity of compounds from Kaempferia parviflora.

Journal: Journal of ethnopharmacology 20080227

Title: Cytotoxic constituents from the fruiting branches of Callicarpa americana collected in southern Florida.

Journal: Journal of natural products 20070301

Title: Studies on Nepalese crude drugs. XXIX. Chemical constituents of Dronapuspi, the whole herb of Leucas cephalotes SPRENG.

Journal: Chemical & pharmaceutical bulletin 20061001

Title: Bioactive tetrahydrofuran lignans from Peperomia dindygulensis.

Journal: Journal of natural products 20051101

Title: [Study on chemical constituents from Incarvillea arguta and their accelerating PC-12 cell differentiation].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050901

Title: [Studies on flavonoids from herb of Artemisia ordosica].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050901

Title: [Studies on the flavonoid constituents in herb of Eremosparton songoricum].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050101

Title: Biological activity of five antibacterial flavonoids from Combretum erythrophyllum (Combretaceae).

Journal: Journal of ethnopharmacology 20040801

Title: Antioxidant activity of Egyptian Eucalyptus camaldulensis var. brevirostris leaf extracts.

Journal: Die Nahrung 20030201

Title: Spasmolytic effects of baccharis conferta and some of its constituents.

Journal: The Journal of pharmacy and pharmacology 20020101

Title: Aquiledine and isoaquiledine, novel flavonoid alkaloids from Aquilegia ecalcarata.

Journal: Journal of natural products 20010101

Title: Interactions of flavonoids and other phytochemicals with adenosine receptors.

Journal: Journal of medicinal chemistry 19960202

Title: Alvarez, M.E. et al.Phytochemical study and anti-inflammatory properties of Lampaya hieronymi Schum. ex Moldenke.Farmaco. Jun-Jul;55(6-7):502-5.doi:10.1016/S0014-827X(00)00067-7(2000).

Title: Mangoyi, R., Midiwo, J. & Mukanganyama, S. Isolation and characterization of an antifungal compound 5-hydroxy-7,4'-dimethoxyflavone from Combretum zeyheri. BMC complementary and alternative medicine 15, 405, doi:10.1186/s12906-015-0934-7 (2015).

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