Title: Influence of adult age on the total and free clearance and protein binding of (R)- and (S)-warfarin.
Journal: British journal of clinical pharmacology 20121101
Title: Vorapaxar, an oral PAR-1 receptor antagonist, does not affect the pharmacokinetics and pharmacodynamics of warfarin.
Journal: European journal of clinical pharmacology 20121101
Title: Impact of organic solvents on cytochrome P450 probe reactions: filling the gap with (S)-Warfarin and midazolam hydroxylation.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20121101
Title: Prospective pilot trial of PerMIT versus standard anticoagulation service management of patients initiating oral anticoagulation.
Journal: Thrombosis and haemostasis 20120904
Title: Effect of carisbamate on the pharmacokinetics and pharmacodynamics of warfarin in healthy participants.
Journal: Journal of clinical pharmacology 20120901
Title: A novel relay method for determining low-clearance values.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20120901
Title: CYP4F2 gene polymorphism as a contributor to warfarin maintenance dose in Japanese subjects.
Journal: Journal of clinical pharmacy and therapeutics 20120801
Title: Rosuvastatin suppresses the liver microsomal CYP2C11 and CYP2C6 expression in male Wistar rats.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20120801
Title: The effect of fimasartan, an angiotensin receptor type 1 blocker, on the pharmacokinetics and pharmacodynamics of warfarin in healthy Korean male volunteers: a one-sequence, two-period crossover clinical trial.
Journal: Clinical therapeutics 20120701
Title: Population pharmacokinetic modelling of S-warfarin to evaluate the design of drug-drug interaction studies for CYP2C9.
Journal: Journal of pharmacokinetics and pharmacodynamics 20120401
Title: Decreased warfarin clearance associated with the CYP2C9 R150H (*8) polymorphism.
Journal: Clinical pharmacology and therapeutics 20120401
Title: Warfarin-amiodarone drug-drug interactions: determination of [I](u)/K(I,u) for amiodarone and its plasma metabolites.
Journal: Clinical pharmacology and therapeutics 20120401
Title: Evaluation of methods for achieving stable INR in healthy subjects during a multiple-dose warfarin study.
Journal: European journal of clinical pharmacology 20120301
Title: Screening of chemicals for human bioaccumulative potential with a physiologically based toxicokinetic model.
Journal: Archives of toxicology 20120301
Title: Investigation of drug-drug interactions caused by human pregnane X receptor-mediated induction of CYP3A4 and CYP2C subfamilies in chimeric mice with a humanized liver.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20120301
Title: Pharmacogenetic warfarin dose refinements remain significantly influenced by genetic factors after one week of therapy.
Journal: Thrombosis and haemostasis 20120202
Title: Ginkgo biloba extract attenuates warfarin-mediated anticoagulation through induction of hepatic cytochrome P450 enzymes by bilobalide in mice.
Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20120115
Title: The population pharmacokinetics of R- and S-warfarin: effect of genetic and clinical factors.
Journal: British journal of clinical pharmacology 20120101
Title: Analysis of R- and S-hydroxywarfarin glucuronidation catalyzed by human liver microsomes and recombinant UDP-glucuronosyltransferases.
Journal: The Journal of pharmacology and experimental therapeutics 20120101
Title: Comparison in the in vitro inhibitory effects of major phytocannabinoids and polycyclic aromatic hydrocarbons contained in marijuana smoke on cytochrome P450 2C9 activity.
Journal: Drug metabolism and pharmacokinetics 20120101
Title: Energetics based spike generation of a single neuron: simulation results and analysis.
Journal: Frontiers in neuroenergetics 20120101
Title: [Enantioselective determinination of R-warfarin/S-warfarin in human plasma using liquid chromatography-tandem mass spectrometry and its application in a drug-drug interaction study].
Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20120101
Title: Stereoselective regulations of P-glycoprotein by ginsenoside Rh2 epimers and the potential mechanisms from the view of pharmacokinetics.
Journal: PloS one 20120101
Title: Therapeutic dosing of acenocoumarol: proposal of a population specific pharmacogenetic dosing algorithm and its validation in north Indians.
Journal: PloS one 20120101
Title: Warfarin and miconazole oral gel interactions: analysis and therapy recommendations based on clinical data and a pharmacokinetic model.
Journal: Journal of clinical pharmacy and therapeutics 20111201
Title: Warfarin drug interactions: a comparative evaluation of the lists provided by five information sources.
Journal: European journal of clinical pharmacology 20111201
Title: Fenofibrate-induced decrease of expression of CYP2C11 and CYP2C6 in rat.
Journal: Biopharmaceutics & drug disposition 20111101
Title: Individual differences in prothrombin time-international normalized ratio variation following coadministration of the anticancer agents S-1 and warfarin: 3 case reports.
Journal: International journal of clinical pharmacology and therapeutics 20111101
Title: Drug interaction of (S)-warfarin, and not (R)-warfarin, with itraconazole in a hematopoietic stem cell transplant recipient.
Journal: Clinica chimica acta; international journal of clinical chemistry 20111009
Title: Influence of CYP2C9 and VKORC1 polymorphisms on warfarin and acenocoumarol in a sample of Lebanese people.
Journal: Journal of clinical pharmacology 20111001
Title: Quantification of total and free concentrations of R- and S-warfarin in human plasma by ultrafiltration and LC-MS/MS.
Journal: Analytical and bioanalytical chemistry 20111001
Title: Drug-drug interaction study to assess the effects of multiple-dose pitavastatin on steady-state warfarin in healthy adult volunteers.
Journal: Journal of clinical pharmacology 20110901
Title: Are there differences in the catalytic activity per unit enzyme of recombinantly expressed and human liver microsomal cytochrome P450 2C9? A systematic investigation into inter-system extrapolation factors.
Journal: Biopharmaceutics & drug disposition 20110901
Title: Novel multi-mode ultra performance liquid chromatography-tandem mass spectrometry assay for profiling enantiomeric hydroxywarfarins and warfarin in human plasma.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110501
Title: Effect of linagliptin on the pharmacokinetics and pharmacodynamics of warfarin in healthy volunteers.
Journal: International journal of clinical pharmacology and therapeutics 20110501
Title: The neuroprotective agent DP-b99 does not interact with s-warfarin in vivo despite significant CYP2C9 inhibition in vitro.
Journal: Basic & clinical pharmacology & toxicology 20110401
Title: Genetics of warfarin sensitivity in an emergency department population with thromboembolic.
Journal: The western journal of emergency medicine 20110201
Title: Clinical drugs undergoing polymorphic metabolism by human cytochrome P450 2C9 and the implication in drug development.
Journal: Current medicinal chemistry 20110101
Title: Effects of nilotinib on single-dose warfarin pharmacokinetics and pharmacodynamics: a randomized, single-blind, two-period crossover study in healthy subjects.
Journal: Clinical drug investigation 20110101
Title: Interactions between Natural Health Products and Oral Anticoagulants: Spontaneous Reports in the Italian Surveillance System of Natural Health Products.
Journal: Evidence-based complementary and alternative medicine : eCAM 20110101
Title: Place of pitavastatin in the statin armamentarium: promising evidence for a role in diabetes mellitus.
Journal: Drug design, development and therapy 20110101
Title: Genetic factors associated with patient-specific warfarin dose in ethnic Indonesians.
Journal: BMC medical genetics 20110101
Title: Drug metabolizing enzyme activities versus genetic variances for drug of clinical pharmacogenomic relevance.
Journal: Clinical proteomics 20110101
Title: The effect of CYP2C9, VKORC1 genotypes and old age on warfarin pharmacologic sensitivity in korean patients with thromboembolic disease.
Journal: Annals of clinical and laboratory science 20110101
Title: Safety and efficacy of dronedarone in the treatment of atrial fibrillation/flutter.
Journal: Clinical Medicine Insights. Cardiology 20110101
Title: Clinical and genetic determinants of warfarin pharmacokinetics and pharmacodynamics during treatment initiation.
Journal: PloS one 20110101
Title: Gene-drug interaction in stroke.
Journal: Stroke research and treatment 20110101
Title: A case of diffuse alveolar hemorrhage associated with tegafur plus uracil and warfarin therapy.
Journal: Clinical medicine insights. Case reports 20110101
Title: Polymorphisms of human cytochrome P450 2C9 and the functional relevance.
Journal: Toxicology 20101205
Title: Contribution of three CYP3A isoforms to metabolism of R- and S-warfarin.
Journal: Drug metabolism letters 20101201
Title: Stereoselective interactions of warfarin enantiomers with the pregnane X nuclear receptor in gene regulation of major drug-metabolizing cytochrome P450 enzymes.
Journal: Journal of thrombosis and haemostasis : JTH 20101201
Title: Effect of oseltamivir treatment on anticoagulation: a cross-over study in warfarinized patients.
Journal: British journal of clinical pharmacology 20101201
Title: Warfarin toxicity and individual variability-clinical case.
Journal: Toxins 20101101
Title: Effect of single-dose rifampin on the pharmacokinetics of warfarin in healthy volunteers.
Journal: Clinical pharmacology and therapeutics 20101001
Title: Standard warfarin dose in a patient with the CYP2C9*3/*3 genotype leads to hematuria.
Journal: Clinica chimica acta; international journal of clinical chemistry 20100906
Title: Entrapment of proteins in glycogen-capped and hydrazide-activated supports.
Journal: Analytical biochemistry 20100901
Title: Interaction between warfarin and the herbal product Shengmai-yin: a case report of intracerebral hematoma.
Journal: Yonsei medical journal 20100901
Title: Simultaneous measurement of S-warfarin, R-warfarin, S-7-hydroxywarfarin and R-7-hydroxywarfarin in human plasma by liquid chromatography-tandem mass spectrometry.
Journal: Journal of pharmaceutical and biomedical analysis 20100605
Title: A pharmacometric model describing the relationship between warfarin dose and INR response with respect to variations in CYP2C9, VKORC1, and age.
Journal: Clinical pharmacology and therapeutics 20100601
Title: Hydroxywarfarin metabolites potently inhibit CYP2C9 metabolism of S-warfarin.
Journal: Chemical research in toxicology 20100517
Title: Effect of casopitant, a novel NK-1 receptor antagonist, on the pharmacokinetics and pharmacodynamics of steady-state warfarin.
Journal: Journal of clinical pharmacology 20100501
Title: Pharmacokinetic and pharmacodynamic interactions of echinacea and policosanol with warfarin in healthy subjects.
Journal: British journal of clinical pharmacology 20100501
Title: Two flavonolignans from milk thistle (Silybum marianum) inhibit CYP2C9-mediated warfarin metabolism at clinically achievable concentrations.
Journal: The Journal of pharmacology and experimental therapeutics 20100301
Title: Ethnic differences in the population pharmacokinetics and pharmacodynamics of warfarin.
Journal: Journal of pharmacokinetics and pharmacodynamics 20100201
Title: Time-dependent inhibition (TDI) of CYP3A4 and CYP2C9 by noscapine potentially explains clinical noscapine-warfarin interaction.
Journal: British journal of clinical pharmacology 20100201
Title: Effect of eslicarbazepine acetate on the steady-state pharmacokinetics and pharmacodynamics of warfarin in healthy subjects during a three-stage, open-label, multiple-dose, single-period study.
Journal: Clinical therapeutics 20100101
Title: Optimal loading dose for the initiation of warfarin: a systematic review.
Journal: BMC cardiovascular disorders 20100101
Title: Assessment of chimeric mice with humanized liver as a tool for predicting circulating human metabolites.
Journal: Drug metabolism and pharmacokinetics 20100101
Title: Pharmacogenetics of anticoagulants.
Journal: Human genomics and proteomics : HGP 20100101
Title: Feasibility of incorporating genomic knowledge into electronic medical records for pharmacogenomic clinical decision support.
Journal: BMC bioinformatics 20100101
Title: Statistical design of personalized medicine interventions: the Clarification of Optimal Anticoagulation through Genetics (COAG) trial.
Journal: Trials 20100101
Title: Update on treatment of partial onset epilepsy: role of eslicarbazepine.
Journal: Neuropsychiatric disease and treatment 20100101
Title: VKORC1 pharmacogenetics and pharmacoproteomics in patients on warfarin anticoagulant therapy: transthyretin precursor as a potential biomarker.
Journal: PloS one 20100101
Title: Rosuvastatin, inflammation, C-reactive protein, JUPITER, and primary prevention of cardiovascular disease--a perspective.
Journal: Drug design, development and therapy 20100101
Title: Pharmacogenetics in the brazilian population.
Journal: Frontiers in pharmacology 20100101
Title: Effects of duloxetine on the pharmacodynamics and pharmacokinetics of warfarin at steady state in healthy subjects.
Journal: Journal of clinical pharmacology 20091201
Title: New insights into the structural features and functional relevance of human cytochrome P450 2C9. Part II.
Journal: Current drug metabolism 20091201
Title: [Prednisolone affects Waran medication].
Journal: Lakartidningen 20091201
Title: New high-performance liquid chromatography method for the determination of (R)-warfarin and (S)-warfarin using chiral separation on a glycopeptide-based stationary phase.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20091001
Title: Interactive modeling for ongoing utility of pharmacogenetic diagnostic testing: application for warfarin therapy.
Journal: Clinical chemistry 20091001
Title: Genetic polymorphism of the human cytochrome P450 2C9 gene and its clinical significance.
Journal: Current drug metabolism 20090901
Title: Warfarin-dosing algorithm based on a population pharmacokinetic/pharmacodynamic model combined with Bayesian forecasting.
Journal: Pharmacogenomics 20090801
Title: R(+)XK469 inhibits hydroxylation of S-warfarin by CYP2C9.
Journal: European journal of cancer (Oxford, England : 1990) 20090701
Title: The absence of an interaction between warfarin and cranberry juice: a randomized, double-blind trial.
Journal: Journal of clinical pharmacology 20090701
Title: Implications of pharmacogenetics for oral anticoagulants metabolism.
Journal: Current drug metabolism 20090701
Title: CYP2C9 amino acid residues influencing phenytoin turnover and metabolite regio- and stereochemistry.
Journal: The Journal of pharmacology and experimental therapeutics 20090601
Title: CYP4F2 is a vitamin K1 oxidase: An explanation for altered warfarin dose in carriers of the V433M variant.
Journal: Molecular pharmacology 20090601
Title: Equine cytochrome P450 2C92: cDNA cloning, expression and initial characterization.
Journal: Archives of biochemistry and biophysics 20090501
Title: Personalizing health care--is this the right time for warfarin?
Journal: Journal of general internal medicine 20090501
Title: Noncompetitive peak decay analysis of drug-protein dissociation by high-performance affinity chromatography.
Journal: Journal of separation science 20090501
Title: The pharmacokinetics and pharmacodynamics of warfarin in combination with ambrisentan in healthy volunteers.
Journal: British journal of clinical pharmacology 20090501
Title: Prediction of the effects of genetic polymorphism on the pharmacokinetics of CYP2C9 substrates from in vitro data.
Journal: Pharmaceutical research 20090401
Title: Effect of rutin on warfarin anticoagulation and pharmacokinetics of warfarin enantiomers in rats.
Journal: The Journal of pharmacy and pharmacology 20090401
Title: Effect of ethanol on S-warfarin and diclofenac metabolism by recombinant human CYP2C9.1.
Journal: Biological & pharmaceutical bulletin 20090301
Title: Pharmacogenomics of warfarin: uncovering a piece of the warfarin mystery.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20090115
Title: Mechanism-based inactivation of cytochrome P450 2C9 by tienilic acid and (+/-)-suprofen: a comparison of kinetics and probe substrate selection.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20090101
Title: Prediction of human disposition toward S-3H-warfarin using chimeric mice with humanized liver.
Journal: Drug metabolism and pharmacokinetics 20090101
Title: Influence of laropiprant, a selective prostaglandin D2 receptor 1 antagonist, on the pharmacokinetics and pharmacodynamics of warfarin.
Journal: American journal of therapeutics 20090101
Title: Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development.
Journal: Current medicinal chemistry 20090101
Title: Casopitant: a novel NK(1)-receptor antagonist in the prevention of chemotherapy-induced nausea and vomiting.
Journal: Therapeutics and clinical risk management 20090101
Title: VKORC1 diplotype-derived dosing model to explain variability in warfarin dose requirements in Asian patients.
Journal: Drug metabolism and pharmacokinetics 20090101
Title: The effectiveness of physical activity monitoring and distance counselling in an occupational health setting--a research protocol for a randomised controlled trial (CoAct).
Journal: BMC public health 20090101
Title: CYP2C9-catalyzed metabolism of S-warfarin to 7-hydroxywarfarin in vivo and in vitro in chimeric mice with humanized liver.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20081201
Title: Studies of verapamil binding to human serum albumin by high-performance affinity chromatography.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20081201
Title: Functional analysis of phenylalanine residues in the active site of cytochrome P450 2C9.
Journal: Biochemistry 20081111
Title: Re-engineering of CYP2C9 to probe acid-base substrate selectivity.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20081001
Title: Effect of nebicapone on the pharmacokinetics and pharmacodynamics of warfarin in healthy subjects.
Journal: European journal of clinical pharmacology 20081001
Title: Role of pharmacogenomics in drug discovery and development.
Journal: Indian journal of pharmacology 20080801
Title: Prediction of pharmacokinetic drug-drug interactions using human hepatocyte suspension in plasma and cytochrome P450 phenotypic data. III. In vitro-in vivo correlation with fluconazole.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20080701
Title: Evaluation of a potential tigecycline-warfarin drug interaction.
Journal: Pharmacotherapy 20080701
Title: The role of cytochrome P2C19 in R-warfarin pharmacokinetics and its interaction with omeprazole.
Journal: Therapeutic drug monitoring 20080601
Title: [Green tea can reduce the effect of Waran].
Journal: Lakartidningen 20080601
Title: Combination of phenotype assessments and CYP2C9-VKORC1 polymorphisms in the determination of warfarin dose requirements in heavily medicated patients.
Journal: Clinical pharmacology and therapeutics 20080501
Title: Intracerebral hemorrhage secondary to a warfarin-metronidazole interaction.
Journal: The American journal of geriatric pharmacotherapy 20080301
Title: The effect of CYP2C19 genotypes on the pharmacokinetics of warfarin enantiomers.
Journal: Journal of clinical pharmacy and therapeutics 20080201
Title: [Do Cardizem and Waran interact?].
Journal: Lakartidningen 20080201
Title: Glucuronidation of monohydroxylated warfarin metabolites by human liver microsomes and human recombinant UDP-glucuronosyltransferases.
Journal: The Journal of pharmacology and experimental therapeutics 20080101
Title: Lack of pharmacokinetic and pharmacodynamic interactions between a smoking cessation therapy, varenicline, and warfarin: an in vivo and in vitro study.
Journal: Journal of clinical pharmacology 20071101
Title: [Marevan and blood platelet inhibitors in surgery].
Journal: Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20071101
Title: Effective virtual screening protocol for CYP2C9 ligands using a screening site constructed from flurbiprofen and S-warfarin pockets.
Journal: Journal of computer-aided molecular design 20070901
Title: Inhibitory effects of angiotensin receptor blockers on CYP2C9 activity in human liver microsomes.
Journal: Drug metabolism and pharmacokinetics 20070801
Title: The use of mechanistic DM-PK-PD modelling to assess the power of pharmacogenetic studies -CYP2C9 and warfarin as an example.
Journal: British journal of clinical pharmacology 20070701
Title: Exposure of raptors and waterbirds to anticoagulant rodenticides (difenacoum, bromadiolone, coumatetralyl, coumafen, brodifacoum): epidemiological survey in Loire Atlantique (France).
Journal: Bulletin of environmental contamination and toxicology 20070701
Title: Estimation of warfarin maintenance dose based on VKORC1 (-1639 G>A) and CYP2C9 genotypes.
Journal: Clinical chemistry 20070701
Title: The effect of 1-furan-2-yl-3-pyridine-2-yl-propenone on pharmacokinetic parameters of warfarin.
Journal: Archives of pharmacal research 20070701
Title: Effects of daily ingestion of cranberry juice on the pharmacokinetics of warfarin, tizanidine, and midazolam--probes of CYP2C9, CYP1A2, and CYP3A4.
Journal: Clinical pharmacology and therapeutics 20070601
Title: Simultaneous determination of warfarin enantiomers and its metabolite in human plasma by column-switching high-performance liquid chromatography with chiral separation.
Journal: Therapeutic drug monitoring 20070601
Title: Effect of the novel oral dipeptidyl peptidase IV inhibitor vildagliptin on the pharmacokinetics and pharmacodynamics of warfarin in healthy subjects.
Journal: Current medical research and opinion 20070501
Title: A PK-PD model for predicting the impact of age, CYP2C9, and VKORC1 genotype on individualization of warfarin therapy.
Journal: Clinical pharmacology and therapeutics 20070401
Title: Plasma S/R ratio of warfarin co-varies with VKORC1 haplotype.
Journal: Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20070401
Title: Association of warfarin dose with genes involved in its action and metabolism.
Journal: Human genetics 20070301
Title: Interaction potential between cranberry juice and warfarin.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20070301
Title: Warfarin and cytochrome P450 2C9 genotype: possible ethnic variation in warfarin sensitivity.
Journal: Pharmacogenomics 20070301
Title: Evaluation of cryopreserved human hepatocytes as an alternative in vitro system to microsomes for the prediction of metabolic clearance.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20070201
Title: Highly enantioselective michael addition of cyclic 1,3-dicarbonyl compounds to alpha,beta-unsaturated ketones.
Journal: Organic letters 20070201
Title: A review of sitaxsentan sodium in patients with pulmonary arterial hypertension.
Journal: Vascular health and risk management 20070201
Title: In silico prediction of pregnane X receptor activators by machine learning approaches.
Journal: Molecular pharmacology 20070101
Title: Significant pharmacokinetic and pharmacodynamic interaction of warfarin with the NO-independent sGC activator HMR1766.
Journal: Journal of clinical pharmacology 20070101
Title: Cinacalcet does not affect the pharmacokinetics or pharmacodynamics of warfarin.
Journal: Drugs in R&D 20070101
Title: Warfarin dosing and the promise of pharmacogenomics.
Journal: Current clinical pharmacology 20070101
Title: Prioritization of clinical drug interaction studies using in vitro cytochrome P450 data: proposed refinement and expansion of the 'rank order' approach.
Journal: Drug metabolism letters 20070101
Title: Supercritical fluid chromatography-tandem mass spectrometry for fast bioanalysis of R/S-warfarin in human plasma.
Journal: Journal of pharmaceutical and biomedical analysis 20061116
Title: Enzyme source effects on CYP2C9 kinetics and inhibition.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20061101
Title: Investigation of the effects of herbal medicines on warfarin response in healthy subjects: a population pharmacokinetic-pharmacodynamic modeling approach.
Journal: Journal of clinical pharmacology 20061101
Title: Effect of exenatide on the pharmacokinetics and pharmacodynamics of warfarin in healthy Asian men.
Journal: Journal of clinical pharmacology 20061001
Title: Effect of glimepiride and glibenclamide on S-warfarin 7-hydroxylation by human liver microsomes, recombinant human CYP2C9.1 and CYP2C9.3.
Journal: Biological & pharmaceutical bulletin 20060901
Title: Computational solvent mapping reveals the importance of local conformational changes for broad substrate specificity in mammalian cytochromes P450.
Journal: Biochemistry 20060808
Title: Stability of warfarin solutions for drug-protein binding measurements: spectroscopic and chromatographic studies.
Journal: Journal of pharmaceutical and biomedical analysis 20060616
Title: Effects of lasofoxifene on the pharmacokinetics and pharmacodynamics of single-dose warfarin.
Journal: British journal of clinical pharmacology 20060601
Title: Effects of fluvastatin and cigarette smoking on CYP2C9 activity measured using the probe S-warfarin.
Journal: European journal of clinical pharmacology 20060601
Title: Prediction of in vivo drug clearance from in vitro data. II: potential inter-ethnic differences.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20060601
Title: Evaluation of the drug interaction potential of aplaviroc, a novel human immunodeficiency virus entry inhibitor, using a modified cooperstown 5 + 1 cocktail.
Journal: Journal of clinical pharmacology 20060501
Title: [Pain relief in patients treated with Waran].
Journal: Lakartidningen 20060401
Title: [Waran following thrombolysis with Actilyse].
Journal: Lakartidningen 20060301
Title: [Interaction between Waran and cranberry juice].
Journal: Lakartidningen 20060301
Title: [Pharmacogenetics of warfarin].
Journal: Vnitrni lekarstvi 20060301
Title: Different contributions of polymorphisms in VKORC1 and CYP2C9 to intra- and inter-population differences in maintenance dose of warfarin in Japanese, Caucasians and African-Americans.
Journal: Pharmacogenetics and genomics 20060201
Title: Ginkgo biloba does not alter clearance of flurbiprofen, a cytochrome P450-2C9 substrate.
Journal: Journal of clinical pharmacology 20060201
Title: Inhibitory effect of 5-fluorouracil on cytochrome P450 2C9 activity in cancer patients.
Journal: Basic & clinical pharmacology & toxicology 20060201
Title: Drug interaction between capecitabine and warfarin: a case report and review of the literature.
Journal: International journal of clinical pharmacology and therapeutics 20060201
Title: Contribution of CYP2C9 to variability in vitamin K antagonist metabolism.
Journal: Expert opinion on drug metabolism & toxicology 20060201
Title: Ginkgo biloba: evaluation of CYP2C9 drug interactions in vitro and in vivo.
Journal: American journal of therapeutics 20060101
Title: Prediction of the clearance of eleven drugs and associated variability in neonates, infants and children.
Journal: Clinical pharmacokinetics 20060101
Title: Resource consumption and management associated with monitoring of warfarin treatment in primary health care in Sweden.
Journal: BMC family practice 20060101
Title: DrugMetZ DB: an anthology of human drug metabolizing Chytochrome P450 enzymes.
Journal: Bioinformation 20060101
Title: A new high-performance liquid chromatographic method for determination of warfarin enantiomers.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20051105
Title: The impact of CYP2C9 and VKORC1 genetic polymorphism and patient characteristics upon warfarin dose requirements: proposal for a new dosing regimen.
Journal: Blood 20051001
Title: Pharmacokinetics and pharmacodynamics of warfarin when coadministered with pentosan polysulfate sodium.
Journal: Journal of clinical pharmacology 20050801
Title: Significant effect of capecitabine on the pharmacokinetics and pharmacodynamics of warfarin in patients with cancer.
Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050720
Title: In-vitro and in-vivo effects of the CYP2C9*11 polymorphism on warfarin metabolism and dose.
Journal: Pharmacogenetics and genomics 20050701
Title: Pharmacogenetic testing: proofs of principle and pharmacoeconomic implications.
Journal: Mutation research 20050603
Title: Characterization of the T-cell response in a patient with phenindione hypersensitivity.
Journal: The Journal of pharmacology and experimental therapeutics 20050601
Title: Common genetic variants of microsomal epoxide hydrolase affect warfarin dose requirements beyond the effect of cytochrome P450 2C9.
Journal: Clinical pharmacology and therapeutics 20050501
Title: Effect of ginkgo and ginger on the pharmacokinetics and pharmacodynamics of warfarin in healthy subjects.
Journal: British journal of clinical pharmacology 20050401
Title: Effect of gemfibrozil on the pharmacokinetics and pharmacodynamics of racemic warfarin in healthy subjects.
Journal: British journal of clinical pharmacology 20050401
Title: Effect of coenzyme Q10 on warfarin hydroxylation in rat and human liver microsomes.
Journal: Current drug metabolism 20050401
Title: Lansoprazole enantiomer activates human liver microsomal CYP2C9 catalytic activity in a stereospecific and substrate-specific manner.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20050201
Title: Moxifloxacin-warfarin interaction: a series of five case reports.
Journal: The Annals of pharmacotherapy 20050201
Title: Interaction of warfarin with drugs, natural substances, and foods.
Journal: Journal of clinical pharmacology 20050201
Title: Prediction of in vitro intrinsic clearance from hepatocytes: comparison of suspensions and monolayer cultures.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20050101
Title: Clinical consequences of cytochrome P450 2C9 polymorphisms.
Journal: Clinical pharmacology and therapeutics 20050101
Title: Influence of CYP2C9 polymorphisms, demographic factors and concomitant drug therapy on warfarin metabolism and maintenance dose.
Journal: The pharmacogenomics journal 20050101
Title: Anticoagulant treatment at a specialized outpatient anticoagulant therapy unit, a descriptive study.
Journal: Thrombosis journal 20050101
Title: Effects of avasimibe on cytochrome P450 2C9 expression in vitro and in vivo.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20041201
Title: High-performance affinity monolith chromatography: development and evaluation of human serum albumin columns.
Journal: Analytical chemistry 20041201
Title: Upstream and coding region CYP2C9 polymorphisms: correlation with warfarin dose and metabolism.
Journal: Pharmacogenetics 20041201
Title: Inhibitory effect of antituberculosis drugs on human cytochrome P450-mediated activities.
Journal: Journal of pharmacological sciences 20041101
Title: Effect of the oral renin inhibitor aliskiren on the pharmacokinetics and pharmacodynamics of a single dose of warfarin in healthy subjects.
Journal: British journal of clinical pharmacology 20041001
Title: Ginkgo biloba extract modifies hypoglycemic action of tolbutamide via hepatic cytochrome P450 mediated mechanism in aged rats.
Journal: Life sciences 20040716
Title: Limited sampling strategy of S-warfarin concentrations, but not warfarin S/R ratios, accurately predicts S-warfarin AUC during baseline and inhibition in CYP2C9 extensive metabolizers.
Journal: Journal of clinical pharmacology 20040601
Title: Effect of St John's wort and ginseng on the pharmacokinetics and pharmacodynamics of warfarin in healthy subjects.
Journal: British journal of clinical pharmacology 20040501
Title: The impact of CYP2C9 genetics and oral contraceptives on cytochrome P450 2C9 phenotype.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20040501
Title: Potential of pranlukast and zafirlukast in the inhibition of human liver cytochrome P450 enzymes.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20040501
Title: 5'-Flanking region polymorphisms of CYP2C9 and their relationship to S-warfarin metabolism in white and Japanese patients.
Journal: Blood 20040415
Title: Differential roles of Arg97, Asp293, and Arg108 in enzyme stability and substrate specificity of CYP2C9.
Journal: Molecular pharmacology 20040401
Title: CYP2C9 genetic polymorphisms and warfarin.
Journal: Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20040401
Title: Evaluation of potential inductive effects of aprepitant on cytochrome P450 3A4 and 2C9 activity.
Journal: Journal of clinical pharmacology 20040301
Title: Contribution of age, body size, and CYP2C9 genotype to anticoagulant response to warfarin.
Journal: Clinical pharmacology and therapeutics 20040301
Title: Effects of CYP2C9 polymorphisms on the pharmacokinetics of R- and S-phenprocoumon in healthy volunteers.
Journal: Pharmacogenetics 20040101
Title: Clinical pharmacology of bosentan, a dual endothelin receptor antagonist.
Journal: Clinical pharmacokinetics 20040101
Title: Combination of chiral capillary electrochromatography with electrospray ionization mass spectrometry: method development and assay of warfarin enantiomers in human plasma.
Journal: Analytical chemistry 20031115
Title: Mechanism-based inhibition of human liver microsomal cytochrome P450 1A2 by zileuton, a 5-lipoxygenase inhibitor.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20031101
Title: Mechanism-based inactivation of human recombinant P450 2C9 by the nonsteroidal anti-inflammatory drug suprofen.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20031101
Title: Combined phenotypic assessment of cytochrome p450 1A2, 2C9, 2C19, 2D6, and 3A, N-acetyltransferase-2, and xanthine oxidase activities with the 'Cooperstown 5+1 cocktail'.
Journal: Clinical pharmacology and therapeutics 20031101
Title: Clinical relevance of genetic polymorphisms in the human CYP2C9 gene.
Journal: European journal of clinical investigation 20031101
Title: Polymorphism in CYP2C9 as a non-critical factor of warfarin dosage adjustment in Korean patients.
Journal: Archives of pharmacal research 20031101
Title: Kiiv, an in vivo parameter for predicting the magnitude of a drug interaction arising from competitive enzyme inhibition.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20030801
Title: No major difference in inhibitory susceptibility between CYP2C9.1 and CYP2C9.3.
Journal: European journal of clinical pharmacology 20030701
Title: Polymorphism induced sensitivity to warfarin: a review of the literature.
Journal: Journal of thrombosis and thrombolysis 20030601
Title: Comparative pharmacokinetics of coumarin anticoagulants L: Physiologic modeling of S-warfarin in rats and pharmacologic target-mediated warfarin disposition in man.
Journal: Journal of pharmaceutical sciences 20030501
Title: Clopidogrel and warfarin: absence of interaction in patients receiving long-term anticoagulant therapy for non-valvular atrial fibrillation.
Journal: Thrombosis and haemostasis 20030501
Title: Population differences in S-warfarin metabolism between CYP2C9 genotype-matched Caucasian and Japanese patients.
Journal: Clinical pharmacology and therapeutics 20030301
Title: mRNA and protein expression of dog liver cytochromes P450 in relation to the metabolism of human CYP2C substrates.
Journal: Xenobiotica; the fate of foreign compounds in biological systems 20030301
Title: Molecular basis of sulindac competition with specific markers for the major binding sites on human serum albumin.
Journal: Arzneimittel-Forschung 20030101
Title: Pharmacokinetic interactions with rifampicin : clinical relevance.
Journal: Clinical pharmacokinetics 20030101
Title: High-performance liquid-chromatographic determination of warfarin enantiomers in plasma with automated on-line sample enrichment.
Journal: Journal of biochemical and biophysical methods 20021231
Title: Evaluation of cytochrome P450 probe substrates commonly used by the pharmaceutical industry to study in vitro drug interactions.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20021201
Title: Influence of CYP2C9 and CYP2C19 genetic polymorphisms on warfarin maintenance dose and metabolic clearance.
Journal: Clinical pharmacology and therapeutics 20021201
Title: Warfarin dose adjustments based on CYP2C9 genetic polymorphisms.
Journal: Journal of thrombosis and thrombolysis 20021201
Title: An approach for the quantitative consideration of genetic polymorphism data in chemical risk assessment: examples with warfarin and parathion.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20021101
Title: Lack of pharmacokinetic interactions between argatroban and warfarin.
Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20021101
Title: Analysis of CYP2C9*5 in Caucasian, Oriental and black-African populations.
Journal: European journal of clinical pharmacology 20021101
Title: Effect of 5-fluorouracil on the anticoagulant activity and the pharmacokinetics of warfarin enantiomers in rats.
Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20021001
Title: Stereoselective kinetics of warfarin binding to human serum albumin: effect of an allosteric interaction.
Journal: Chirality 20020515
Title: Effect of the catechol-O-methyltransferase inhibitor entacapone on the steady-state pharmacokinetics and pharmacodynamics of warfarin.
Journal: British journal of clinical pharmacology 20020501
Title: Effect of modafinil at steady state on the single-dose pharmacokinetic profile of warfarin in healthy volunteers.
Journal: Journal of clinical pharmacology 20020201
Title: Major bleeding caused by warfarin in a genetically susceptible patient.
Journal: Pharmacotherapy 20020101
Title: In vivo effect of 5- and 8-methoxypsoralens and cimetidine on R,S-warfarin metabolism in rat.
Journal: Journal of applied toxicology : JAT 20020101
Title: Effect of tolterodine on the anticoagulant actions and pharmacokinetics of single-dose warfarin in healthy volunteers.
Journal: Arzneimittel-Forschung 20020101
Title: The role of CYP2C9 genotype in the metabolism of diclofenac in vivo and in vitro.
Journal: European journal of clinical pharmacology 20011201
Title: Lack of effect of repeated administration of levetiracetam on the pharmacodynamic and pharmacokinetic profiles of warfarin.
Journal: Epilepsy research 20011101
Title: Possible interaction between warfarin and Lycium barbarum L.
Journal: The Annals of pharmacotherapy 20011001
Title: Inhibition and inactivation of human cytochrome P450 isoforms by phenethyl isothiocyanate.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20010801
Title: Identification and functional characterization of a new CYP2C9 variant (CYP2C9*5) expressed among African Americans.
Journal: Molecular pharmacology 20010801
Title: Interindividual variability in sensitivity to warfarin--Nature or nurture?
Journal: Clinical pharmacology and therapeutics 20010801
Title: Effects of oral vitamin K on S- and R-warfarin pharmacokinetics and pharmacodynamics: enhanced safety of warfarin as a CYP2C9 probe.
Journal: Journal of clinical pharmacology 20010701
Title: Divergent effects of raloxifene HCI on the pharmacokinetics and pharmacodynamics of warfarin.
Journal: Pharmaceutical research 20010701
Title: Crystal structure analysis of warfarin binding to human serum albumin: anatomy of drug site I.
Journal: The Journal of biological chemistry 20010622
Title: In vitro stimulation of warfarin metabolism by quinidine: increases in the formation of 4'- and 10-hydroxywarfarin.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20010601
Title: Analysis of free drug fractions by ultrafast immunoaffinity chromatography.
Journal: Analytical chemistry 20010515
Title: Metabolism of sulfinpyrazone sulfide and sulfinpyrazone by human liver microsomes and cDNA-expressed cytochrome P450s.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20010501
Title: The effect of anastrozole on the single-dose pharmacokinetics and anticoagulant activity of warfarin in healthy volunteers.
Journal: British journal of clinical pharmacology 20010501
Title: Interaction between warfarin and danshen (Salvia miltiorrhiza).
Journal: The Annals of pharmacotherapy 20010401
Title: The stereoselective effects of bucolome on the pharmacokinetics and pharmacodynamics of racemic warfarin.
Journal: Journal of clinical pharmacology 20010401
Title: Characterization and purification of the vitamin K1 2,3 epoxide reductases system from rat liver.
Journal: The Journal of pharmacy and pharmacology 20010401
Title: Study of the retention properties of warfarin enantiomers on a beta-cyclodextrin polymeric support.
Journal: Journal of chromatography. B, Biomedical sciences and applications 20010325
Title: [Hypersensitivity to oral anticoagulants: report of a case].
Journal: Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology 20010301
Title: Implications of cytochrome P450 2C9 polymorphism on warfarin metabolism and dosing.
Journal: Pharmacotherapy 20010201
Title: Oral anticoagulants. Pharmacologic issues for use in the elderly.
Journal: Clinics in geriatric medicine 20010201
Title: Effect of ubidecarenone on warfarin anticoagulation and pharmacokinetics of warfarin enantiomers in rats.
Journal: Drug metabolism and drug interactions 20010101
Title: Pharmacogenetics of warfarin elimination and its clinical implications.
Journal: Clinical pharmacokinetics 20010101
Title: CYP2C9*3 influences the metabolism and the drug-interaction of candesartan in vitro.
Journal: The pharmacogenomics journal 20010101
