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32507-66-7,MFCD12407151
Catalog No.:AA00I62W

32507-66-7 | Isorhapontigenin

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Purity
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1mg
95%
in stock  
$7.00   $5.00
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5mg
95%
in stock  
$22.00   $15.00
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10mg
95%
in stock  
$37.00   $26.00
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100mg
>96.0%(GC)
in stock  
$131.00   $92.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA00I62W
Chemical Name:
Isorhapontigenin
CAS Number:
32507-66-7
Molecular Formula:
C15H14O4
Molecular Weight:
258.2693
MDL Number:
MFCD12407151
SMILES:
COc1cc(/C=C/c2cc(O)cc(c2)O)ccc1O
Properties
Computed Properties
 
Complexity:
295  
Covalently-Bonded Unit Count:
1  
Defined Bond Stereocenter Count:
1  
Heavy Atom Count:
19  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
3  
XLogP3:
3.2  

Downstream Synthesis Route

[1]LiebigsAnnalenderChemie,1992,p.399-402

[2]CanadianJournalofChemistry,1968,vol.46,p.2525-2529

[1]LiebigsAnnalenderChemie,1992,p.399-402

[2]CanadianJournalofChemistry,1968,vol.46,p.2525-2529

6689-43-6   
(3,5-dihydroxybenzyl)triphenylphosphoniumbromide 
  32507-66-7 

[1]JustusLiebigsAnnalenderChemie,1971,vol.750,p.109-127

[1]BioorganicandMedicinalChemistry,2001,vol.9,p.41-50

[2]CanadianJournalofChemistry,1968,vol.46,p.2525-2529

[3]BioorganicandMedicinalChemistry,2001,vol.9,p.1887-1893

[1]CanadianJournalofChemistry,1968,vol.46,p.2525-2529

Literature

Title: Potent Inhibition of HIV-1 Replication in Resting CD4 T Cells by Resveratrol and Pterostilbene.

Journal: Antimicrobial agents and chemotherapy 20170901

Title: Isorhapontigenin: a novel bioactive stilbene from wine grapes.

Journal: Food chemistry 20121201

Title: The Chinese herb isolate isorhapontigenin induces apoptosis in human cancer cells by down-regulating overexpression of antiapoptotic protein XIAP.

Journal: The Journal of biological chemistry 20121012

Title: [Synthesis and HIV-1 inhibitory activity of natural products isolated from Gnetum parvifolium and their analogues].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20101201

Title: Isorhapontigenin, a new resveratrol analog, attenuates cardiac hypertrophy via blocking signaling transduction pathways.

Journal: Free radical biology & medicine 20050115

Title: Isorhapontigenin and resveratrol suppress oxLDL-induced proliferation and activation of ERK1/2 mitogen-activated protein kinases of bovine aortic smooth muscle cells.

Journal: Biochemical pharmacology 20040215

Title: Effect of isorhapontigenin on respiratory burst of rat neutrophils.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20021201

Title: An isorhapontigenin tetramer and a novel stilbene dimer from Gnetum hainanense.

Journal: Planta medica 20021001

Title: Antioxidative activity of natural isorhapontigenin.

Journal: Japanese journal of pharmacology 20010901

Title: A novel cyclooxygenase-inhibitory stilbenolignan from the seeds of Aiphanes aculeata.

Journal: Organic letters 20010712

Title: Four new stilbene dimers from the lianas of Gnetum hainanense.

Journal: Journal of Asian natural products research 20010101

Title: Yeo SCM, et al. Isorhapontigenin, a bioavailable dietary polyphenol, suppresses airway epithelial cell inflammation through a corticosteroid-independent mechanism. Br J Pharmacol. 2017 Jul;174(13):2043-2059.

Title: Liang Y, et al. SESN2/sestrin 2 induction-mediated autophagy and inhibitory effect of isorhapontigenin (ISO) on human bladder cancers. Autophagy. 2016 Aug 2;12(8):1229-39.

Title: Jiang G, et al. Isorhapontigenin (ISO) Inhibits Invasive Bladder Cancer Formation In Vivo and Human Bladder Cancer Invasion In Vitro by Targeting STAT1/FOXO1 Axis. Cancer Prev Res (Phila). 2016 Jul;9(7):567-80.

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SDS
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