Home Amines 1015787-98-0
1015787-98-0,MFCD24539325
Catalog No.:AA0004RL

1015787-98-0 | Benzenesulfonamide, 5-[(2,4-diamino-5-pyrimidinyl)oxy]-2-methoxy-4-(1-methylethyl)-

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
99.72%
1 week  
$118.00   $83.00
- +
2mg
99.72%
1 week  
$136.00   $95.00
- +
5mg
99.72%
1 week  
$171.00   $120.00
- +
10mg
99.72%
1 week  
$218.00   $153.00
- +
25mg
99.72%
1 week  
$365.00   $256.00
- +
50mg
99.72%
1 week  
$550.00   $385.00
- +
100mg
99.72%
1 week  
$857.00   $600.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0004RL
Chemical Name:
Benzenesulfonamide, 5-[(2,4-diamino-5-pyrimidinyl)oxy]-2-methoxy-4-(1-methylethyl)-
CAS Number:
1015787-98-0
Molecular Formula:
C14H19N5O4S
Molecular Weight:
353.3968
MDL Number:
MFCD24539325
SMILES:
COc1cc(C(C)C)c(cc1S(=O)(=O)N)Oc1cnc(nc1N)N
Properties
Computed Properties
 
Complexity:
512  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
24  
Hydrogen Bond Acceptor Count:
9  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
5  
XLogP3:
0.7  

Literature

Title: Medicinal chemistry of adenosine, P2Y and P2X receptors.

Journal: Neuropharmacology 20160501

Title: P2X3 receptor antagonist (AF-219) in refractory chronic cough: a randomised, double-blind, placebo-controlled phase 2 study.

Journal: Lancet (London, England) 20150328

Title: Potential for developing purinergic drugs for gastrointestinal diseases.

Journal: Inflammatory bowel diseases 20140701

Title: The therapeutic promise of ATP antagonism at P2X3 receptors in respiratory and urological disorders.

Journal: Frontiers in cellular neuroscience 20130101

Title: Anthony P. Ford, et al. The therapeutic promise of ATP antagonism at P2X3 receptors in respiratory and urological disorders. Front Cell Neurosci. 2013; 7: 267.

Title: Ford AP, In pursuit of P2X3 antagonists: novel therapeutics for chronic pain and afferent sensitization. Purinergic Signal. 2012 Feb;8(Suppl 1):3-26.

Title: Martin Nguyen A, et al. Validation of a visual analog scale for assessing cough severity in patients with chronic cough. Ther Adv Respir Dis. 2021 Jan-Dec;15:17534666211049743.

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SDS
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Tags:1015787-98-0 Molecular Formula|1015787-98-0 MDL|1015787-98-0 SMILES|1015787-98-0 Benzenesulfonamide, 5-[(2,4-diamino-5-pyrimidinyl)oxy]-2-methoxy-4-(1-methylethyl)-