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109-09-1,MFCD00006228
Catalog No.:AA00IKAQ

109-09-1 | 2-Chloropyridine

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1g
99%(GC)
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$24.00   $17.00
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25g
>98.0%(GC)
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500g
98%
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00IKAQ
Chemical Name:
2-Chloropyridine
CAS Number:
109-09-1
Molecular Formula:
C5H4ClN
Molecular Weight:
113.5450
MDL Number:
MFCD00006228
SMILES:
C1=CC=NC(=C1)Cl
NSC Number:
4649
UN Number:
2822
Properties
Properties
 
BP:
170.0°C  
Storage:
Room Temperature;Keep in dry area;  

Computed Properties
 
Complexity:
56  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
7  
Hydrogen Bond Acceptor Count:
1  
XLogP3:
1.2  

Literature

Title: A novel halogen bond and a better-known hydrogen bond cooperation of neonicotinoid and insect nicotinic acetylcholine receptor recognition.

Journal: Journal of molecular modeling 20120801

Title: Replacing conventional carbon nucleophiles with electrophiles: nickel-catalyzed reductive alkylation of aryl bromides and chlorides.

Journal: Journal of the American Chemical Society 20120411

Title: An alternative synthetic route for an antidiabetic drug, rosiglitazone.

Journal: Bioorganic & medicinal chemistry letters 20120115

Title: Discovery of a novel class of orally active trypanocidal N-myristoyltransferase inhibitors.

Journal: Journal of medicinal chemistry 20120112

Title: Experimental investigation of the absolute enthalpies of formation of 2,3-, 2,4-, and 3,4-pyridynes.

Journal: The journal of physical chemistry. A 20110922

Title: Adamantyl ethanone pyridyl derivatives: potent and selective inhibitors of human 11β-hydroxysteroid dehydrogenase type 1.

Journal: ChemMedChem 20110905

Title: 1,3-Bis(pyridin-2-yl)-1H-benzimidazol-3-ium tetra-fluoridoborate.

Journal: Acta crystallographica. Section E, Structure reports online 20110801

Title: Oxonium picrate.

Journal: Acta crystallographica. Section E, Structure reports online 20110701

Title: (Z)-N-{3-[(6-Chloro-pyridin-3-yl)meth-yl]-1,3-thia-zolidin-2-yl-idene}cyanamide.

Journal: Acta crystallographica. Section E, Structure reports online 20110501

Title: Molecular design of dinotefuran with unique insecticidal properties.

Journal: Journal of agricultural and food chemistry 20110413

Title: The synthesis and preclinical evaluation in rhesus monkey of [¹⁸F]MK-6577 and [¹¹C]CMPyPB glycine transporter 1 positron emission tomography radiotracers.

Journal: Synapse (New York, N.Y.) 20110401

Title: Discovery and optimization of a series of benzothiazole phosphoinositide 3-kinase (PI3K)/mammalian target of rapamycin (mTOR) dual inhibitors.

Journal: Journal of medicinal chemistry 20110324

Title: Synthesis, characterization, and monkey PET studies of [¹⁸F]MK-1312, a PET tracer for quantification of mGluR1 receptor occupancy by MK-5435.

Journal: Synapse (New York, N.Y.) 20110201

Title: Palladium-catalyzed indole, pyrrole, and furan arylation by aryl chlorides.

Journal: The Journal of organic chemistry 20110121

Title: Etoricoxibium picrate.

Journal: Acta crystallographica. Section E, Structure reports online 20110101

Title: Furan-2,5-dimethylene-tethered bis-imidacloprid insecticide conferring high potency.

Journal: Journal of agricultural and food chemistry 20101124

Title: Synthesis, biological evaluation, and molecular docking studies of 2-chloropyridine derivatives possessing 1,3,4-oxadiazole moiety as potential antitumor agents.

Journal: Bioorganic & medicinal chemistry 20101115

Title: Aminopyrazine inhibitors binding to an unusual inactive conformation of the mitotic kinase Nek2: SAR and structural characterization.

Journal: Journal of medicinal chemistry 20101111

Title: Phenyl- and benzylurea cytokinins as competitive inhibitors of cytokinin oxidase/dehydrogenase: a structural study.

Journal: Biochimie 20100801

Title: Synthesis and molecular docking studies of novel 2-chloro-pyridine derivatives containing flavone moieties as potential antitumor agents.

Journal: Bioorganic & medicinal chemistry letters 20100715

Title: Biotransformation of thianicotinyl neonicotinoid insecticides: diverse molecular substituents response to metabolism by bacterium Stenotrophomonas maltophilia CGMCC 1.1788.

Journal: Bioresource technology 20100601

Title: Synthesis of polyhalogenated 4,4'-bipyridines via a simple dimerization procedure.

Journal: The Journal of organic chemistry 20100521

Title: Genotoxicity study of photolytically treated 2-chloropyridine aqueous solutions.

Journal: Journal of hazardous materials 20100515

Title: Phantasmidine: an epibatidine congener from the ecuadorian poison frog Epipedobates anthonyi.

Journal: Journal of natural products 20100326

Title: Metalation of pyridines with nBuLi-Li-aminoalkoxide mixed aggregates: The origin of chemoselectivity.

Journal: Journal of the American Chemical Society 20100224

Title: Palladium-catalyzed chemoselective monoarylation of hydrazides for the synthesis of [1,2,4]triazolo[4,3-a]pyridines.

Journal: Organic letters 20100219

Title: New pyridone, thioxopyridine, pyrazolopyridine and pyridine derivatives that modulate inflammatory mediators in stimulated RAW 264.7 murine macrophage.

Journal: European journal of medicinal chemistry 20091101

Title: 2-Hydroxypyridine photolytic degradation by 254 nm UV irradiation at different conditions.

Journal: Chemosphere 20091101

Title: Aromatic substitution reaction of 2-chloropyridines catalyzed by microsomal glutathione S-transferase 1.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20090901

Title: Photolytic removal and mineralisation of 2-halogenated pyridines.

Journal: Water research 20090901

Title: Bis-neonicotinoid insecticides: Observed and predicted binding interactions with the nicotinic receptor.

Journal: Bioorganic & medicinal chemistry letters 20090701

Title: Ethyl 1-(6-chloro-3-pyridylmeth-yl)-5-methyl-1H-1,2,3-triazole-4-carboxyl-ate.

Journal: Acta crystallographica. Section E, Structure reports online 20081201

Title: A versatile cyclodehydration reaction for the synthesis of isoquinoline and beta-carboline derivatives.

Journal: Organic letters 20080821

Title: Toward prediction of alkane/water partition coefficients.

Journal: Journal of medicinal chemistry 20080710

Title: Crystal structures of Lymnaea stagnalis AChBP in complex with neonicotinoid insecticides imidacloprid and clothianidin.

Journal: Invertebrate neuroscience : IN 20080601

Title: Dibenzyl penta-thio-dicarbonate.

Journal: Acta crystallographica. Section E, Structure reports online 20080101

Title: Synthesis and nicotinic acetylcholine receptor binding properties of bridged and fused ring analogues of epibatidine.

Journal: Journal of medicinal chemistry 20071213

Title: Modular and practical synthesis of 6-substituted pyridin-3-yl C-nucleosides.

Journal: The Journal of organic chemistry 20070831

Title: Photolytic (UVC) and photocatalyic (UVC/TiO2) decomposition of pyridines.

Journal: Journal of hazardous materials 20070731

Title: Synthesis of pyrimidines by direct condensation of amides and nitriles.

Journal: Nature protocols 20070101

Title: [Benzo[c][2,7]naphthyridine-2-yl-, 5-yl- and 2,5-diyl novaldiamines--synthesis and investigation of anti-malarial activity].

Journal: Die Pharmazie 20061201

Title: Theoretical prediction of relative and absolute pKa values of aminopyridines.

Journal: Biophysical chemistry 20061120

Title: Single-step synthesis of pyrimidine derivatives.

Journal: Journal of the American Chemical Society 20061108

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Total synthesis of ageladine A, an angiogenesis inhibitor from the marine sponge Agelas nakamurai.

Journal: Organic letters 20060330

Title: Synthesis and evaluation of new chiral nonracemic C2-symmetric and unsymmetric 2,2'-bipyridyl ligands.

Journal: Organic & biomolecular chemistry 20060307

Title: Selective indole-based ECE inhibitors: synthesis and pharmacological evaluation.

Journal: ChemMedChem 20060101

Title: N-oxide analogs of WAY-100635: new high affinity 5-HT(1A) receptor antagonists.

Journal: Bioorganic & medicinal chemistry 20050201

Title: Comparative analysis of neonicotinoid binding to insect membranes: I. A structure-activity study of the mode of [3H]imidacloprid displacement in Myzus persicae and Aphis craccivora.

Journal: Pest management science 20041001

Title: Adsorption of 2-chloropyridine on oxides--an infrared spectroscopic study.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20031101

Title: Aminoborohydrides 15. The first mild and efficient method for generating 2-(dialkylamino)-pyridines from 2-fluoropyridine.

Journal: Organic letters 20031016

Title: The discovery of dinotefuran: a novel neonicotinoid.

Journal: Pest management science 20030901

Title: First regioselective ortho-lithiation induced by a 2-chloropyridyl group complexation.

Journal: The Journal of organic chemistry 20030613

Title: No stirring necessary: parallel carbonylation of aryl halides with CO and various alcohols under pressure.

Journal: The Journal of organic chemistry 20030502

Title: Nucleophilic aromatic substitution reactions of chloroazines with bisulfide (HS-) and polysulfides (Sn2-).

Journal: Environmental science & technology 20020501

Title: Analgesic and toxic effects of neonicotinoid insecticides in mice.

Journal: Toxicology and applied pharmacology 20011115

Title: The discovery of thiamethoxam: a second-generation neonicotinoid.

Journal: Pest management science 20010201

Title: exo-2-(Pyridazin-4-yl)-7-azabicyclo[2.2.1]heptanes: syntheses and nicotinic acetylcholine receptor agonist activity of potent pyridazine analogues of (+/-)-epibatidine.

Journal: Journal of medicinal chemistry 20010104

Title: Mode of action and quantitative structure-activity correlations of tuberculostatic drugs of the isonicotinic acid hydrazide type.

Journal: Journal of medicinal chemistry 19760401

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