Home Iodos 1122-44-7
1122-44-7,MFCD00023162
Catalog No.:AA003MQI

1122-44-7 | 5-Iodocytosine

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100mg
98%
in stock  
$13.00   $9.00
- +
250mg
98%
in stock  
$16.00   $11.00
- +
2g
95%
in stock  
$26.00   $18.00
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5g
95%
in stock  
$60.00   $42.00
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10g
95%
in stock  
$116.00   $81.00
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25g
95%
in stock  
$249.00   $174.00
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  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA003MQI
Chemical Name:
5-Iodocytosine
CAS Number:
1122-44-7
Molecular Formula:
C4H4IN3O
Molecular Weight:
236.9985
MDL Number:
MFCD00023162
SMILES:
Nc1nc(=O)[nH]cc1I
Properties
Properties
 
BP:
480.2 °C at 760 mmHg  
Form:
Solid  
MP:
250 °C  
Storage:
Inert atmosphere;-20 ℃;  

Computed Properties
 
Complexity:
208  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
9  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
2  
XLogP3:
-0.5  

Upstream Synthesis Route

[1]Patent:US7741294,2010,B1,.Locationinpatent:Page/Pagecolumn17

[2]EuropeanJournalofOrganicChemistry,2015,vol.2015,#32,p.7160-7175

[3]JournalofMedicinalChemistry,1983,vol.26,#2,p.152-156

[4]Tetrahedron,2012,vol.68,#26,p.5145-5151

[5]JournalofHeterocyclicChemistry,2015,vol.52,#5,p.1382-1389

[6]Synthesis,2003,#7,p.1039-1042

[7]JournaloftheAmericanChemicalSociety,2008,vol.130,#27,p.8762-8768

[8]JournalofBiologicalChemistry,1906,vol.1,p.310

[9]Chem.Zentralbl.,1906,vol.77,#I,p.1890

[10]StructuralChemistry,2010,vol.21,#1,p.245-254

[11]Molecules,2017,vol.22,#12,

[1]BioorganicandMedicinalChemistry,2016,vol.24,#8,p.1771-1777

Downstream Synthesis Route
2-ethylsulfanyl-5-iodo-pyrimidin-4-ylamine 
  1122-44-7 

[1]JournalofBiologicalChemistry,1906,vol.1,p.310    ChemischesZentralblatt,1906,vol.77,p.1890

[1]Patent:US7741294,2010,B1.Locationinpatent:Page/Pagecolumn17

[2]EuropeanJournalofOrganicChemistry,2015,vol.2015,p.7160-7175

[3]JournalofMedicinalChemistry,1983,vol.26,p.152-156

[4]Tetrahedron,2012,vol.68,p.5145-5151

[5]JournalofHeterocyclicChemistry,2015,vol.52,p.1382-1389

[6]Synthesis,2003,p.1039-1042

[7]JournaloftheAmericanChemicalSociety,2008,vol.130,p.8762-8768

[8]Chemistry-AEuropeanJournal,2019,vol.25,p.1773-1780

[9]JournalofBiologicalChemistry,1906,vol.1,p.310    ChemischesZentralblatt,1906,vol.77,p.1890

[10]StructuralChemistry,2010,vol.21,p.245-254

[11]Molecules,2017,vol.22

[1]JournalofMedicinalChemistry,1983,vol.26,p.152-156

1122-44-7    103824-47-1   
C22H20IN3O6 

[1]JournalofMedicinalChemistry,1988,vol.31,p.144-149

1122-44-7    870-63-3   
4-amino-5-iodo-1-(3-methyl-2-buten-1-yl)pyrimidin-2(1H)-one 

[1]JournalofHeterocyclicChemistry,1995,vol.32,p.1513-1515

Literature

Title: Synthesis of aldehyde-linked nucleotides and DNA and their bioconjugations with lysine and peptides through reductive amination.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20120326

Title: Alkylsulfanylphenyl derivatives of cytosine and 7-deazaadenine nucleosides, nucleotides and nucleoside triphosphates: synthesis, polymerase incorporation to DNA and electrochemical study.

Journal: Chemistry (Weinheim an der Bergstrasse, Germany) 20110516

Title: Structural basis for cyclic Py-Im polyamide allosteric inhibition of nuclear receptor binding.

Journal: Journal of the American Chemical Society 20101020

Title: Mouse RS21-C6 is a mammalian 2'-deoxycytidine 5'-triphosphate pyrophosphohydrolase that prefers 5-iodocytosine.

Journal: The FEBS journal 20090301

Title: Synthesis and DNA incorporation of an ethynyl-bridged cytosine C-nucleoside as guanosine surrogate.

Journal: Organic letters 20071206

Title: A direct synthesis of pyrrolocytosine from 5-iodocytosine.

Journal: Nucleosides, nucleotides & nucleic acids 20050101

Title: Nucleobase modified peptide nucleic acid.

Journal: Nucleosides, nucleotides & nucleic acids 20030101

Title: Condensation of nucleobases at mercury/aqueous solution interface--a structural perspective using hydrogen bonding considerations.

Journal: Journal of colloid and interface science 20020601

Title: The GTP-dependent restriction enzyme McrBC from Escherichia coli forms high-molecular mass complexes with DNA and produces a cleavage pattern with a characteristic 10-base pair repeat.

Journal: Biochemistry 20020423

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