Home Amines 112257-19-9
112257-19-9,MFCD09953267
Catalog No.:AA0038WB

112257-19-9 | tert-Butyl methyl(2-(methylamino)ethyl)carbamate

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Purity
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1g
97%
in stock  
$6.00   $4.00
- +
5g
97%
in stock  
$17.00   $12.00
- +
10g
97%
in stock  
$22.00   $15.00
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25g
97%
in stock  
$53.00   $37.00
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100g
97%
in stock  
$188.00   $132.00
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  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Upstream Synthesis Route
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA0038WB
Chemical Name:
tert-Butyl methyl(2-(methylamino)ethyl)carbamate
CAS Number:
112257-19-9
Molecular Formula:
C9H20N2O2
Molecular Weight:
188.2673
MDL Number:
MFCD09953267
SMILES:
CNCCN(C(=O)OC(C)(C)C)C
Properties
Computed Properties
 
Complexity:
164  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
13  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
5  
XLogP3:
0.7  

Upstream Synthesis Route

[1]JournalofMedicinalChemistry,1992,vol.35,#3,p.559-567

[2]OrganicLetters,2008,vol.10,#8,p.1517-1520

[3]OrganicandBiomolecularChemistry,2010,vol.8,#8,p.1777-1780

[4]JournaloftheAmericanChemicalSociety,2014,vol.136,#9,p.3695-3704

[5]JournalofMedicinalChemistry,1990,vol.33,#1,p.97-101

[6]BioorganicandMedicinalChemistryLetters,2017,vol.27,#20,p.4635-4642

[7]ChemicalCommunications,2018,vol.54,#38,p.4878-4881

[8]JournalofMaterialsChemistryB,2014,vol.2,#44,p.7685-7693

[9]Patent:WO2016/46574,2016,A1,.Locationinpatent:Page/Pagecolumn149;150

[10]JournalofMedicinalChemistry,2000,vol.43,#16,p.3093-3102

[11]ChemicalandPharmaceuticalBulletin,2011,vol.59,#11,p.1355-1362

[12]ChemicalCommunications,2015,vol.51,#21,p.4410-4413

[13]Patent:WO2008/42353,2008,A1,.Locationinpatent:Page/Pagecolumn35;43

[14]Patent:WO2008/42353,2008,A1,.Locationinpatent:Page/Pagecolumn35;43

[15]Patent:US4902706,1990,A,

[16]Patent:WO2013/14448,2013,A1,.Locationinpatent:Page/Pagecolumn158

[17]JournalofMedicinalChemistry,2014,vol.57,#20,p.8249-8267

[18]JournaloftheAmericanChemicalSociety,2009,vol.131,#51,p.18327-18334

[19]Patent:WO2007/26027,2007,A1,.Locationinpatent:Page/Pagecolumn36-37

[20]JournalofMedicinalChemistry,2011,vol.54,#4,p.1033-1058

[21]Patent:WO2010/58353,2010,A1,.Locationinpatent:Page/Pagecolumn71-72

[22]Patent:US2011/224210,2011,A1,.Locationinpatent:Page/Pagecolumn49

[23]TetrahedronLetters,2008,vol.49,#24,p.3921-3924

[24]Patent:US6335324,2002,B1,.Locationinpatent:Pagecolumn128

[25]Patent:US2011/172240,2011,A1,.Locationinpatent:Page/Pagecolumn39;40

[26]Molecules,2012,vol.17,#5,p.5346-5362

[27]JournalofMaterialsChemistryB,2017,vol.5,#14,p.2635-2643

[28]Patent:WO2018/41763,2018,A1,.Locationinpatent:Page/Pagecolumn43

[29]Patent:US5344830,1994,A,

[30]Patent:CN108707139,2018,A,.Locationinpatent:Paragraph0315;0318;0319;0320

[1]JournaloftheAmericanChemicalSociety,2010,vol.132,#28,p.9540-9542

[2]JournalofMedicinalChemistry,2009,vol.52,#3,p.779-797

[1]Patent:WO2006/23400,2006,A2,.Locationinpatent:Page/Pagecolumn150-151

[2]NewJournalofChemistry,2016,vol.41,#1,p.126-133

Downstream Synthesis Route

[1]Belvisi,Laura;Borlandelli,Valentina;Corno,Cristina;DalCorso,Alberto;Gennari,Cesare;Perego,Paola;Pignataro,Luca[AngewandteChemie-InternationalEdition,2020,vol.59,#10,p.4176-4181][Angew.Chem.,2020,vol.132,#10,p.4205-4210,6]

[2]Bian,Qiang;Peng,Xing-Jie;Tian,Xue-Rong;Zhao,Tong-Tong;Zhao,Wei-Guang[JournalofHeterocyclicChemistry,2022]

[3]Kleemann,Heinz-Werner;Heitsch,Holger;Henning,Rainer;Kramer,Werner;Kocher,Walter;etal.[JournalofMedicinalChemistry,1992,vol.35,#3,p.559-567]

[4]Meyer,Yves;Richard,Jean-Alexandre;Massonneau,Marc;Renard,Pierre-Yves;Romieu,Anthony[OrganicLetters,2008,vol.10,#8,p.1517-1520]

[5]Meyer,Yves;Richard,Jean-Alexandre;Delest,Bruno;Noack,Pauline;Renard,Pierre-Yves;Romieu,Anthony[OrganicandBiomolecularChemistry,2010,vol.8,#8,p.1777-1780]

[6]Barbot,Thomas;Beswick,Veronica;Cao,Xiu-Xiu;Huang,Dong-Liang;Jamin,Nadège;Jaxel,Christine;Li,Ying;Liang,Jun;Montigny,Cédric;Tian,Chang-Lin;Xue,Min;Zheng,Ji-Shen;Zheng,Yong[AngewandteChemie-InternationalEdition,2020,vol.59,#13,p.5178-5184][Angew.Chem.,2020,vol.132,#13,p.5216-5222,7]

[7]Zheng,Ji-Shen;Yu,Mu;Qi,Yun-Kun;Tang,Shan;Shen,Fei;Wang,Zhi-Peng;Xiao,Liang;Zhang,Longhua;Tian,Chang-Lin;Liu,Lei[JournaloftheAmericanChemicalSociety,2014,vol.136,#9,p.3695-3704]

[8]Saari,WalfredS.;Schwering,JohnE.;Lyle,PauletteA.;Smith,StevenJ.;Engelhardt,EdwardL.[JournalofMedicinalChemistry,1990,vol.33,#1,p.97-101]

[9]Yang,Hao;Ouyang,Yifan;Ma,Hao;Cong,Hui;Zhuang,Chunlin;Lok,Wun-Taai;Wang,Zhe;Zhu,Xuanli;Sun,Yutong;Hong,Wei;Wang,Hao[BioorganicandMedicinalChemistryLetters,2017,vol.27,#20,p.4635-4642]

[10]Wang,Ruibo;Cai,Kaimin;Wang,Hua;Yin,Chen;Cheng,Jianjun[ChemicalCommunications,2018,vol.54,#38,p.4878-4881]

[11]Mascret,Aïda;Mouhsine,Hadley;Attia,Ghada;Cabrera,Damien;Benchekroun,Mohamed;Gizzi,Patrick;Zerrouki,Chouki;Fourati,Najla;Zagury,Jean-François;Veitía,MaitéSylla-Iyarreta;Port,Marc[EuropeanJournalofPharmacology,2021,vol.907]

[12]Shah,Shreyas;Sasmal,PijusK.;Lee,Ki-Bum[JournalofMaterialsChemistryB,2014,vol.2,#44,p.7685-7693]

[13]CurrentPatentAssignee:ANTIKORBIOPHARMA-WO2016/46574,2016,A1Locationinpatent:Page/Pagecolumn149;150

[14]DeGroot;VanBerkom;Scheeren[JournalofMedicinalChemistry,2000,vol.43,#16,p.3093-3102]

[15]Locationinpatent:schemeortableAriyasu,Shinya;Hanaya,Kengo;Tsunoda,Megumi;Kitamura,Masanori;Hayase,Masanori;Abe,Ryo;Aoki,Shin[ChemicalandPharmaceuticalBulletin,2011,vol.59,#11,p.1355-1362]

[16]Pal,Siddhartha;Mukherjee,Manjira;Sen,Buddhadeb;Mandal,SushilKumar;Lohar,Somenath;Chattopadhyay,Pabitra;Dhara,Koushik[ChemicalCommunications,2015,vol.51,#21,p.4410-4413]

[17]CurrentPatentAssignee:NORTHWESTERNUNIVERSITY(ILLINOIS)-WO2008/42353,2008,A1Locationinpatent:Page/Pagecolumn35;43

[18]CurrentPatentAssignee:PFIZERINC-US4902706,1990,A

[19]CurrentPatentAssignee:ASTRAZENECAPLC-WO2013/14448,2013,A1Locationinpatent:Page/Pagecolumn158

[20]Finlay,M.RaymondV.;Anderton,Mark;Ashton,Susan;Ballard,Peter;Bethel,PaulA.;Box,MatthewR.;Bradbury,RobertH.;Brown,SimonJ.;Butterworth,Sam;Campbell,Andrew;Chorley,Christopher;Colclough,Nicola;Cross,DarrenA.E.;Currie,GordonS.;Grist,Matthew;Hassall,Lorraine;Hill,GeorgeB.;James,Daniel;James,Michael;Kemmitt,Paul;Klinowska,Teresa;Lamont,Gillian;Lamont,ScottG.;Martin,Nathaniel;McFarland,HeatherL.;Mellor,MartineJ.;Orme,JonathonP.;Perkins,David;Perkins,Paula;Richmond,Graham;Smith,Peter;Ward,RichardA.;Waring,MichaelJ.;Whittaker,David;Wells,Stuart;Wrigley,GailL.[JournalofMedicinalChemistry,2014,vol.57,#20,p.8249-8267]

[21]Fuchida,Hirokazu;Hosokawa,Keitaro;Inamori,Ryo;Koyanagi,Satoru;Kuwata,Keiko;Matsunaga,Naoya;Ohdo,Shigehiro;Ojida,Akio;Ono,Mayumi;Sato,Mami;Shibata,Tomohiro;Shindo,Naoya;Tokunaga,Keisuke;Watari,Kosuke;Xiao-Lin,Guo[ACSMedicinalChemistryLetters,2020,vol.11,#6,p.1137-1144]

[22]Hennecker,Christopher;Mittermaier,Anthony;Prinzen,AlexanderL.;Saliba,Daniel;Sleiman,HanadiF.;Trinh,Tuan[AngewandteChemie-InternationalEdition,2020,vol.59,#31,p.12900-12908][Angew.Chem.,2020,vol.132,#31,p.13000-13008,9]

[23]DeWit,MatthewA.;Gillies,ElizabethR.[JournaloftheAmericanChemicalSociety,2009,vol.131,#51,p.18327-18334]

[24]CurrentPatentAssignee:BIOTICATECHNOLOGYLIMITED-WO2007/26027,2007,A1Locationinpatent:Page/Pagecolumn36-37

[25]Locationinpatent:experimentalpartMarugan,JuanJ.;Zheng,Wei;Motabar,Omid;Southall,Noel;Goldin,Ehud;Westbroek,Wendy;Stubblefield,BarbaraK.;Sidransky,Ellen;Aungst,RonaldA.;Lea,WendyA.;Simeonov,Anton;Leister,William;Austin,ChristopherP.[JournalofMedicinalChemistry,2011,vol.54,#4,p.1033-1058]

[26]CurrentPatentAssignee:JOHNSON&JOHNSONINC-WO2010/58353,2010,A1Locationinpatent:Page/Pagecolumn71-72

[27]CurrentPatentAssignee:JOHNSON&JOHNSONINC-US2011/224210,2011,A1Locationinpatent:Page/Pagecolumn49

[28]Wahlström,Karolina;Planstedt,Ove;Undén,Anders[TetrahedronLetters,2008,vol.49,#24,p.3921-3924]

[29]CurrentPatentAssignee:BRISTOL-MYERSSQUIBBCO-US6335324,2002,B1Locationinpatent:Pagecolumn128

[30]CurrentPatentAssignee:CATABASISPHARMACEUTICALS,INC.-US2011/172240,2011,A1Locationinpatent:Page/Pagecolumn39;40

[31]Locationinpatent:experimentalpartXu,Zhigang;Wheeler,KraigA.;Baures,PaulW.[Molecules,2012,vol.17,#5,p.5346-5362]

[32]Li,Bowen;Liu,Peilian;Yan,Donghang;Zeng,Fang;Wu,Shuizhu[JournalofMaterialsChemistryB,2017,vol.5,#14,p.2635-2643]

[33]CurrentPatentAssignee:ROCHEHOLDINGAG-WO2018/41763,2018,A1Locationinpatent:Page/Pagecolumn43

[34]CurrentPatentAssignee:MERCK&COINC-US5344830,1994,A

[35]CurrentPatentAssignee:BEIJINGADAMADLEBIOTECHNOLOGYLIABILITY-CN108707139,2018,ALocationinpatent:Paragraph0315;0318;0319;0320

[36]CurrentPatentAssignee:SICHUANBAILIPHARMACEUTICALCOLTD-CN109106951,2019,ALocationinpatent:Paragraph0105;0106;0107;0108

[37]CurrentPatentAssignee:ROCHEHOLDINGAG-WO2019/166432,2019,A1Locationinpatent:Page/Pagecolumn91

[38]CurrentPatentAssignee:ROCHEHOLDINGAG-US2020/268762,2020,A1Locationinpatent:Paragraph0877-0878

[39]CurrentPatentAssignee:KOREAUNIVERSITY-KR2021/93601,2021,ALocationinpatent:Paragraph0082-0085

[40]Rodrigalvarez,Jesus;Reeve,LukeA.;Miró,Javier;Gaunt,MatthewJ.[JournaloftheAmericanChemicalSociety,2022,vol.144,#9,p.3939-3948]

[41]Zhao,Jiaxing;Zhang,Bing;Mao,Qing;Ping,Kunqi;Zhang,Peng;Lin,Fengwei;Liu,Dan;Feng,Yao;Sun,Ming;Zhang,Yan;Li,QiuHua;Zhang,Tingjian;Mou,Yanhua;Wang,Shaojie[JournalofMedicinalChemistry,2022,vol.65,#6,p.4926-4948]

[42]Schuster,Sabine;Juhász,Éva;Halmos,Gábor;Neundorf,Ines;Gennari,Cesare;Mező,Gábor[InternationalJournalofMolecularSciences,2022,vol.23,#9]

[43]Béroud,Rémy;Boturyn,Didier;Zoukimian,Claude[OrganicLetters,2022]

56055-54-0    112257-19-9   
C16H24ClN3O4 

[1]BioorganicandMedicinalChemistryLetters,2009,vol.19,p.5205-5208

[1]Patent:CN110204532,2019,A.Locationinpatent:Paragraph0037;0108;0112-0114

[2]Patent:WO2013/14448,2013,A1.Locationinpatent:Page/Pagecolumn158

[3]JournalofMedicinalChemistry,2014,vol.57,p.8249-8267

3430-16-8    112257-19-9   
tert-butylN-methyl-N-2-methyl-(5-methyl-3-pyridyl)aminoethylcarbamate 

[1]Patent:WO2013/144179,2013,A1.Locationinpatent:Page/Pagecolumn74

[1]Otrubova,Katerina;Srinivasan,Venkat;Boger,DaleL.[BioorganicandMedicinalChemistryLetters,2014,vol.24,#16,p.3807-3813]

[2]Otrubova,Katerina;Chatterjee,Shreyosree;Ghimire,Srijana;Cravatt,BenjaminF.;Boger,DaleL.[BioorganicandMedicinalChemistry,2019,vol.27,#8,p.1693-1703]

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SDS
Tags:112257-19-9 Molecular Formula|112257-19-9 MDL|112257-19-9 SMILES|112257-19-9 tert-Butyl methyl(2-(methylamino)ethyl)carbamate