Catalog No.:AA001GLW

141625-93-6 | Dronedarone, HCl

Name: Name:Dronedarone, HCl
Brand: AABLOCKS
SKU: AA001GLW
Availability: InStock
Rating: 90 (10 reviews)

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Purity

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Price(USD)

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1mg

95%

in stock

$6.00 $4.00

- +

10mg

95%

in stock

$7.00 $5.00

- +

25mg

95%

in stock

$9.00 $7.00

- +

50mg

95%

in stock

$12.00 $8.00

- +

250mg

95%

in stock

$15.00 $11.00

- +

95%

in stock

$35.00 $25.00

- +

95%

in stock

$100.00 $70.00

- +

10g

95%

in stock

$171.00 $120.00

- +

25g

95%

in stock

$341.00 $239.00

- +

Technical Information
Properties
Downstream Synthesis Route
Literature
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Technical Information
Properties
Downstream Synthesis Route
Literature

Technical Information

Catalog Number:

AA001GLW

Chemical Name:

Dronedarone, HCl

CAS Number:

141625-93-6

Molecular Formula:

C31H45ClN2O5S

Molecular Weight:

593.2174

MDL Number:

MFCD00914940

SMILES:

CCCCc1oc2c(c1C(=O)c1ccc(cc1)OCCCN(CCCC)CCCC)cc(cc2)NS(=O)(=O)C.Cl

Properties

Computed Properties

Complexity:

800

Covalently-Bonded Unit Count:

Heavy Atom Count:

Hydrogen Bond Acceptor Count:

Hydrogen Bond Donor Count:

Rotatable Bond Count:

Downstream Synthesis Route

141645-88-7

437652-07-8

141625-93-6

[1]CurrentPatentAssignee:SANOFI-US2004/48921,2004,A1Locationinpatent:Page/Pagecolumn4

[2]CurrentPatentAssignee:SANOFI-US2004/48921,2004,A1Locationinpatent:Page/Pagecolumn5

[3]CurrentPatentAssignee:YANANBICONPHARMACEUTICALLISTEDCOMPANY-CN103450124,2016,BLocationinpatent:Paragraph0092-0097

141626-36-0

dronedaronehydrochloride

[1]Piotrkowska,Barbara;Nerdinger,Sven;Schreiner,Erwin;Selič,Lovro;Graczyk,PiotrP.[BioorganicandMedicinalChemistry,2018,vol.26,#14,p.4330-4335]

[2]CurrentPatentAssignee:SANOFI-WO2011/70380,2011,A1Locationinpatent:Page/Pagecolumn21

[3]CurrentPatentAssignee:PERMIRAHOLDINGSLIMITED-WO2012/52448,2012,A1Locationinpatent:Page/Pagecolumn14

[4]CurrentPatentAssignee:PERMIRAHOLDINGSLIMITED-EP2447256,2012,A1Locationinpatent:Page/Pagecolumn9

[5]CurrentPatentAssignee:TEVAPHARMACEUTICALINDUSTRIESLTD.-EP2371824,2011,A1Locationinpatent:Page/Pagecolumn9

[6]CurrentPatentAssignee:TEVAPHARMACEUTICALINDUSTRIESLTD.-EP2371808,2011,A1Locationinpatent:Page/Pagecolumn9

[7]CurrentPatentAssignee:SANOFI-US2004/48921,2004,A1Locationinpatent:Page/Pagecolumn5

[8]Li,Feng;Jin,Chunhua;Zou,Jianwei;Wu,Jun[BulletinoftheKoreanChemicalSociety,2014,vol.35,#7,p.1970-1972]

[9]CurrentPatentAssignee:SANOFI-US2004/48921,2004,A1Locationinpatent:Page/Pagecolumn5

[10]CurrentPatentAssignee:SANOFI-US2004/10032,2004,A1Locationinpatent:Page/Pagecolumn6

[11]CurrentPatentAssignee:GLENMARKPHARMACEUTICALSLTD-WO2012/7959,2012,A1Locationinpatent:Page/Pagecolumn21-22

[12]CurrentPatentAssignee:ZYDUSLIFESCIENCESLTD-WO2012/32545,2012,A1Locationinpatent:Page/Pagecolumn36-37

[13]Locationinpatent:experimentalpartHivarekar,RaghvendraR.;Deshmukh,SanjayS.;Tripathy.,NarendraK.[OrganicProcessResearchandDevelopment,2012,vol.16,#4,p.677-681]

[14]CurrentPatentAssignee:MAPIPHARMALTD.-WO2011/99010,2011,A1Locationinpatent:Page/Pagecolumn42

[15]CurrentPatentAssignee:ALEMBICPHARMACEUTICALSLIMITED-WO2012/153225,2012,A1Locationinpatent:Page/Pagecolumn3;13

dronedaronehydrochloride

141626-36-0

[1]CurrentPatentAssignee:SANOFI-EP2354132,2011,A2Locationinpatent:Page/Pagecolumn7

[2]CurrentPatentAssignee:SANOFI-US2004/48921,2004,A1Locationinpatent:Page/Pagecolumn5

[3]CurrentPatentAssignee:USVLTD.-EP2428511,2012,A1Locationinpatent:Page/Pagecolumn11-12

[4]CurrentPatentAssignee:FRICHEMPRIVATE-WO2012/4658,2012,A2Locationinpatent:Page/Pagecolumn20-21

[5]CurrentPatentAssignee:ZYDUSLIFESCIENCESLTD-WO2012/32545,2012,A1Locationinpatent:Page/Pagecolumn41

[6]CurrentPatentAssignee:USVLTD.-US2012/108828,2012,A1Locationinpatent:Page/Pagecolumn8

[7]CurrentPatentAssignee:JIANGSUHENGRUIMEDICINECO.,LTD.-US2013/72697,2013,A1Locationinpatent:Paragraph0058

1310430-09-1

111-92-2

141625-93-6

[1]CurrentPatentAssignee:P&RSPA-WO2011/104591,2011,A1Locationinpatent:Page/Pagecolumn7-8

[2]CurrentPatentAssignee:P&RSPA-US2012/330037,2012,A1Locationinpatent:Page/Pagecolumn3

[3]CurrentPatentAssignee:SANOFI-WO2011/70380,2011,A1

141644-91-9

124-63-0

141625-93-6

[1]CurrentPatentAssignee:USVLTD.-EP2428511,2012,A1Locationinpatent:Page/Pagecolumn10-11

[2]CurrentPatentAssignee:USVLTD.-US2012/108828,2012,A1Locationinpatent:Page/Pagecolumn7

[3]CurrentPatentAssignee:JIANGSUHENGRUIMEDICINECO.,LTD.-EP2581369,2013,A1Locationinpatent:Paragraph0050

[4]CurrentPatentAssignee:JIANGSUHENGRUIMEDICINECO.,LTD.-US2013/72697,2013,A1Locationinpatent:Paragraph0054

[5]Mali,AnilC.;Ippar,SharadS.;Bodke,MahendraB.;Patil,NileshS.;Mathad,VijayavitthalT.[OrganicProcessResearchandDevelopment,2013,vol.17,#5,p.863-868]

[6]CurrentPatentAssignee:FRICHEMPRIVATE-WO2012/4658,2012,A2Locationinpatent:Page/Pagecolumn18

[7]CurrentPatentAssignee:SUNPHARMACEUTICALINDUSTRIESLIMITED-WO2012/120544,2012,A2Locationinpatent:Page/Pagecolumn19

[8]CurrentPatentAssignee:SANOFI-US2013/165675,2013,A1Locationinpatent:Paragraph0043

Literature

Title: Discovery of 1-aryloxyethyl piperazine derivatives as Kv1.5 potassium channel inhibitors (part I).

Journal: European journal of medicinal chemistry 20140623

Title: Bogdan R, et al. Effect of?dronedarone?on Na+, Ca2+ and HCN channels. Naunyn Schmiedebergs Arch Pharmacol.?2011 Apr;383(4):347-56.?

Title: Doggrell SA, et al. Dronedarone: an amiodarone analogue. Expert Opin Investig Drugs. 2004 Apr;13(4):415-26.

Title: Manning AS, et al. SR 33589, a new amiodarone-like agent: effect on ischemia- and reperfusion-induced arrhythmias in anesthetized rats. J Cardiovasc Pharmacol. 1995 Sep;26(3):453-61.

Title: Breitenstein A, et al. Dronedarone reduces arterial thrombus formation. Basic Res Cardiol. 2012 Nov;107(6):302.

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