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141626-36-0,MFCD00910331
Catalog No.:AA001GN3

141626-36-0 | Dronedarone

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
in stock  
$7.00   $5.00
- +
10mg
98%
in stock  
$29.00   $21.00
- +
25mg
98%
in stock  
$48.00   $34.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA001GN3
Chemical Name:
Dronedarone
CAS Number:
141626-36-0
Molecular Formula:
C31H44N2O5S
Molecular Weight:
556.7565
MDL Number:
MFCD00910331
SMILES:
CCCCc1oc2c(c1C(=O)c1ccc(cc1)OCCCN(CCCC)CCCC)cc(cc2)NS(=O)(=O)C
Properties
Computed Properties
 
Complexity:
800  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
39  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
18  
XLogP3:
7.2  

Downstream Synthesis Route
141626-36-0   
dronedaronehydrochloride 

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[2]CurrentPatentAssignee:SANOFI-WO2011/70380,2011,A1Locationinpatent:Page/Pagecolumn21

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[4]CurrentPatentAssignee:PERMIRAHOLDINGSLIMITED-EP2447256,2012,A1Locationinpatent:Page/Pagecolumn9

[5]CurrentPatentAssignee:TEVAPHARMACEUTICALINDUSTRIESLTD.-EP2371824,2011,A1Locationinpatent:Page/Pagecolumn9

[6]CurrentPatentAssignee:TEVAPHARMACEUTICALINDUSTRIESLTD.-EP2371808,2011,A1Locationinpatent:Page/Pagecolumn9

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[9]CurrentPatentAssignee:SANOFI-US2004/48921,2004,A1Locationinpatent:Page/Pagecolumn5

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[11]CurrentPatentAssignee:GLENMARKPHARMACEUTICALSLTD-WO2012/7959,2012,A1Locationinpatent:Page/Pagecolumn21-22

[12]CurrentPatentAssignee:ZYDUSLIFESCIENCESLTD-WO2012/32545,2012,A1Locationinpatent:Page/Pagecolumn36-37

[13]Locationinpatent:experimentalpartHivarekar,RaghvendraR.;Deshmukh,SanjayS.;Tripathy.,NarendraK.[OrganicProcessResearchandDevelopment,2012,vol.16,#4,p.677-681]

[14]CurrentPatentAssignee:MAPIPHARMALTD.-WO2011/99010,2011,A1Locationinpatent:Page/Pagecolumn42

[15]CurrentPatentAssignee:ALEMBICPHARMACEUTICALSLIMITED-WO2012/153225,2012,A1Locationinpatent:Page/Pagecolumn3;13

dronedaronehydrochloride 
  141626-36-0 

[1]CurrentPatentAssignee:SANOFI-EP2354132,2011,A2Locationinpatent:Page/Pagecolumn7

[2]CurrentPatentAssignee:SANOFI-US2004/48921,2004,A1Locationinpatent:Page/Pagecolumn5

[3]CurrentPatentAssignee:USVLTD.-EP2428511,2012,A1Locationinpatent:Page/Pagecolumn11-12

[4]CurrentPatentAssignee:FRICHEMPRIVATE-WO2012/4658,2012,A2Locationinpatent:Page/Pagecolumn20-21

[5]CurrentPatentAssignee:ZYDUSLIFESCIENCESLTD-WO2012/32545,2012,A1Locationinpatent:Page/Pagecolumn41

[6]CurrentPatentAssignee:USVLTD.-US2012/108828,2012,A1Locationinpatent:Page/Pagecolumn8

[7]CurrentPatentAssignee:JIANGSUHENGRUIMEDICINECO.,LTD.-US2013/72697,2013,A1Locationinpatent:Paragraph0058

[1]CurrentPatentAssignee:ZYDUSLIFESCIENCESLTD-WO2012/32545,2012,A1Locationinpatent:Page/Pagecolumn36

[2]CurrentPatentAssignee:PERMIRAHOLDINGSLIMITED-WO2012/52448,2012,A1Locationinpatent:Page/Pagecolumn13

[3]CurrentPatentAssignee:PERMIRAHOLDINGSLIMITED-EP2447256,2012,A1Locationinpatent:Page/Pagecolumn9

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[6]CurrentPatentAssignee:GLENMARKPHARMACEUTICALSLTD-WO2012/7959,2012,A1Locationinpatent:Page/Pagecolumn20-21

[7]CurrentPatentAssignee:GLENMARKPHARMACEUTICALSLTD-WO2012/7959,2012,A1Locationinpatent:Page/Pagecolumn23-24

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Literature

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Title: Utilization of human nuclear receptors as an early counter screen for off-target activity: a case study with a compendium of 615 known drugs.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20150601

Title: Class III antiarrhythmic drug dronedarone inhibits cardiac inwardly rectifying Kir2.1 channels through binding at residue E224.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20141201

Title: Structural basis of drugs that increase cardiac inward rectifier Kir2.1 currents.

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Title: Hepatic toxicity of dronedarone in mice: role of mitochondrial β-oxidation.

Journal: Toxicology 20140902

Title: Discovery of 1-aryloxyethyl piperazine derivatives as Kv1.5 potassium channel inhibitors (part I).

Journal: European journal of medicinal chemistry 20140623

Title: Inhibition of I(f) in the atrioventricular node as a mechanism for dronedarone's reduction in ventricular rate during atrial fibrillation.

Journal: Heart rhythm 20131101

Title: Dronedarone's inhibition of If current is the primary mechanism responsible for its bradycardic effect.

Journal: Journal of cardiovascular electrophysiology 20130801

Title: Mechanisms of hepatocellular toxicity associated with dronedarone--a comparison to amiodarone.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20130201

Title: Drug safety evaluation of dronedarone in atrial fibrillation.

Journal: Expert opinion on drug safety 20121101

Title: Dronedarone reduces arterial thrombus formation.

Journal: Basic research in cardiology 20121101

Title: Management of ventricular and atrial arrhythmias in humans: towards a patient-specific approach.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20121101

Title: Novel electrophysiological properties of dronedarone: inhibition of human cardiac two-pore-domain potassium (K2P) channels.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20121001

Title: The emerging role of amiodarone and dronedarone in Chagas disease.

Journal: Nature reviews. Cardiology 20121001

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Journal: Heart failure reviews 20120901

Title: Meta-analysis of cardiovascular outcomes with dronedarone in patients with atrial fibrillation or heart failure.

Journal: The American journal of cardiology 20120815

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Journal: Current hypertension reports 20120801

Title: Cost-effectiveness of dronedarone in atrial fibrillation: results for Canada, Italy, Sweden, and Switzerland.

Journal: Clinical therapeutics 20120801

Title: Atrial fibrillation: new drugs, devices, and procedures.

Journal: Cleveland Clinic journal of medicine 20120801

Title: Virtual tissue engineering of the human atrium: modelling pharmacological actions on atrial arrhythmogenesis.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20120716

Title: A 73-year-old man with interstitial lung disease due to dronedarone.

Journal: American journal of respiratory and critical care medicine 20120715

Title: Flecainide suppresses defibrillator-induced storming in catecholaminergic polymorphic ventricular tachycardia.

Journal: Pacing and clinical electrophysiology : PACE 20120701

Title: Dronedarone prevents microcirculatory abnormalities in the left ventricle during atrial tachypacing in pigs.

Journal: British journal of pharmacology 20120601

Title: Chronic oral amiodarone but not dronedarone therapy increases ventricular defibrillation threshold during acute myocardial ischemia in a closed-chest animal model.

Journal: Journal of cardiovascular pharmacology 20120601

Title: Pleiotropic effects of dronedarone on ischemia/reperfusion injury in heart and brain.

Journal: Cardiovascular drugs and therapy 20120601

Title: Efficacy and safety profile of dronedarone in clinical practice. Preliminary results of the Magdeburg Dronedarone Registry.

Journal: International journal of cardiology 20120531

Title: Antiarrhythmics for maintaining sinus rhythm after cardioversion of atrial fibrillation.

Journal: The Cochrane database of systematic reviews 20120516

Title: Celivarone for maintenance of sinus rhythm and conversion of atrial fibrillation/flutter.

Journal: Journal of cardiovascular electrophysiology 20120501

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Journal: Giornale italiano di cardiologia (2006) 20120501

Title: rac-Methyl 2-(2-formyl-4-nitro-phen-oxy)hexa-noate.

Journal: Acta crystallographica. Section E, Structure reports online 20120501

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Title: Fatal lung toxic effects related to dronedarone use.

Journal: Archives of internal medicine 20120326

Title: Dronedarone use and fatal lung toxic effects?

Journal: Archives of internal medicine 20120326

Title: Antiarrhythmic drugs for the maintenance of sinus rhythm: risks and benefits.

Journal: International journal of cardiology 20120322

Title: Dronedarone in high-risk permanent atrial fibrillation.

Journal: The New England journal of medicine 20120322

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Journal: The New England journal of medicine 20120322

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Journal: MMW Fortschritte der Medizin 20120322

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Title: [Prevention of cardioembolic stroke].

Journal: Neurologia (Barcelona, Spain) 20120301

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Journal: Lancet (London, England) 20120218

Title: Second chance for dronedarone after recent setback?

Journal: Lancet (London, England) 20120218

Title: Dronedarone: an overview.

Journal: Annals of medicine 20120201

Title: Electrophysiologic profile of dronedarone on the ventricular level: beneficial effect on postrepolarization refractoriness in the presence of rapid phase 3 repolarization.

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Journal: Yonsei medical journal 20120101

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Journal: Deutsches Arzteblatt international 20120101

Title: Managing atrial fibrillation in the elderly: critical appraisal of dronedarone.

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Title: Elevated international normalized ratio associated with use of dronedarone and warfarin.

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Title: Impact of dronedarone on hospitalization burden in patients with atrial fibrillation: results from the ATHENA study.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20110801

Title: Hospitalization: a relevant endpoint in atrial fibrillation management?

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Title: Is antiarrhythmic treatment in the elderly different? a review of the specific changes.

Journal: Drugs & aging 20110801

Title: Acute liver failure associated with dronedarone.

Journal: Circulation. Arrhythmia and electrophysiology 20110801

Title: Atrial fibrillation: outpatient presentation and management.

Journal: Circulation 20110705

Title: Effects of dronedarone on clinical outcomes in patients with lone atrial fibrillation: pooled post hoc analysis from the ATHENA/EURIDIS/ADONIS studies.

Journal: Journal of cardiovascular electrophysiology 20110701

Title: Acute T3 treatment protects the heart against ischemia-reperfusion injury via TRα1 receptor.

Journal: Molecular and cellular biochemistry 20110701

Title: The impact of dronedarone on lone atrial fibrillation: perhaps not such a 'benign' arrhythmia?

Journal: Journal of cardiovascular electrophysiology 20110701

Title: Antiarrhythmic drugs for atrial fibrillation.

Journal: Expert opinion on pharmacotherapy 20110601

Title: Post-ATHENA and beyond.

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Title: Treating arrhythmias: an expert opinion.

Journal: Expert opinion on pharmacotherapy 20110601

Title: Reduction of myocardial infarct size by dronedarone in pigs--a pleiotropic action?

Journal: Cardiovascular drugs and therapy 20110601

Title: Prevention of atrial fibrillation complications with antiarrhythmic drugs: still an unmet need in clinical practice.

Journal: Expert opinion on pharmacotherapy 20110601

Title: Atrial fibrillation: epidemiology, prognosis and therapy.

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Journal: Expert review of cardiovascular therapy 20110601

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Journal: Acta crystallographica. Section E, Structure reports online 20110501

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Journal: Naunyn-Schmiedeberg's archives of pharmacology 20110401

Title: Rhythm- and rate-controlling effects of dronedarone in patients with atrial fibrillation (from the ATHENA trial).

Journal: The American journal of cardiology 20110401

Title: Antiarrhythmic drugs management in patients with atrial fibrillation: the new guidelines.

Journal: Minerva cardioangiologica 20110401

Title: In brief: FDA warning on dronedarone (Multaq).

Journal: The Medical letter on drugs and therapeutics 20110307

Title: Mixed treatment comparison of dronedarone, amiodarone, sotalol, flecainide, and propafenone, for the management of atrial fibrillation.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20110301

Title: Mixed treatment comparisons for atrial fibrillation: evidence network or bewildering entanglement?

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20110301

Title: Dronedarone for atrial fibrillation: How does it compare with amiodarone?

Journal: Cleveland Clinic journal of medicine 20110301

Title: Delayed and indirect effects of antiarrhythmic drugs in reducing sudden cardiac death.

Journal: Future cardiology 20110301

Title: [Perspectives and recommendations for the anti-arrhythmic treatment of atrial fibrillation: focus on dronedarone].

Journal: Revue medicale de Liege 20110301

Title: Suppression of ventricular tachycardia with dronedarone: a case report.

Journal: Journal of cardiovascular electrophysiology 20110201

Title: A patient with recurrent atrial fibrillation and monomorphic ventricular tachycardia treated successfully with dronedarone.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20110201

Title: Atrial fibrillation: what have recent trials taught us regarding pharmacologic management of rate and rhythm control?

Journal: Pacing and clinical electrophysiology : PACE 20110201

Title: Targeting the arrhythmogenic substrate in atrial fibrillation: focus on structural remodeling.

Journal: Current drug targets 20110201

Title: Twenty-five years in the making: flecainide is safe and effective for the management of atrial fibrillation.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20110201

Title: The pharmaceutical pipeline for atrial fibrillation.

Journal: Annals of medicine 20110201

Title: [Epidemiology, clinical picture and management of atrial fibrillation].

Journal: Der Nervenarzt 20110201

Title: An important indirect drug interaction between dronedarone and warfarin that may be extrapolated to other drugs that can alter gastrointestinal function.

Journal: American heart journal 20110201

Title: What's new in...atrial fibrillation. Is dronedarone more effective than amiodarone?

Journal: JAAPA : official journal of the American Academy of Physician Assistants 20110201

Title: Dronedarone.

Journal: Drugs of today (Barcelona, Spain : 1998) 20110201

Title: Ethyl 2-(2-hy-droxy-5-nitro-phen-yl)acetate.

Journal: Acta crystallographica. Section E, Structure reports online 20110201

Title: Dronedarone as a new treatment option for atrial fibrillation patients: pharmacokinetics, pharmacodynamics and clinical practice.

Journal: Expert opinion on pharmacotherapy 20110101

Title: 2011 ACCF/AHA/HRS focused update on the management of patients with atrial fibrillation (Updating the 2006 Guideline): a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines.

Journal: Heart rhythm 20110101

Title: Sinus rhythm restoration and treatment success: insight from recent clinical trials.

Journal: Clinical cardiology 20110101

Title: Dronedarone: current evidence for its safety and efficacy in the management of atrial fibrillation.

Journal: Drug design, development and therapy 20110101

Title: Electrophysiology and adult congenital heart disease: advances and options.

Journal: Progress in cardiovascular diseases 20110101

Title: Comparing the 2010 North American and European atrial fibrillation guidelines.

Journal: The Canadian journal of cardiology 20110101

Title: Canadian Cardiovascular Society atrial fibrillation guidelines 2010: rate and rhythm management.

Journal: The Canadian journal of cardiology 20110101

Title: An Observational, Prospective Survey Assessing the Control of Atrial Fibrillation in Asia Pacific: Rationale and Design of the RecordAF-AP Registry.

Journal: Clinical Medicine Insights. Cardiology 20110101

Title: Dronedarone for the management of atrial fibrillation.

Journal: Swiss medical weekly 20110101

Title: Cost of AF Ablation: Where Do We Stand?

Journal: Cardiology research and practice 20110101

Title: [The research practice of anti-arrhythmic agents targeting on potassium ion channel].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20110101

Title: The pathology and treatment of cardiac arrhythmias: focus on atrial fibrillation.

Journal: Vascular health and risk management 20110101

Title: [Update on current care guidelines: atrial fibrillation].

Journal: Duodecim; laaketieteellinen aikakauskirja 20110101

Title: [The role of dronedarone in the contemporary atrial fibrillation treatment].

Journal: Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20110101

Title: Incidence of atrial fibrillation in patients with either heart failure or acute myocardial infarction and left ventricular dysfunction: a cohort study.

Journal: BMC cardiovascular disorders 20110101

Title: Pharmacological management of atrial fibrillation: one, none, one hundred thousand.

Journal: Cardiology research and practice 20110101

Title: [Amiodarone and thyroid function].

Journal: Kardiologia polska 20110101

Title: Combination ranolazine and dronedarone to suppress atrial fibrillation.

Journal: Reviews in cardiovascular medicine 20110101

Title: Management of patients with atrial fibrillation: specific considerations for the old age.

Journal: Cardiology research and practice 20110101

Title: Incidence and severity of coronary artery disease in patients with atrial fibrillation undergoing first-time coronary angiography.

Journal: PloS one 20110101

Title: Safety and efficacy of dronedarone in the treatment of atrial fibrillation/flutter.

Journal: Clinical Medicine Insights. Cardiology 20110101

Title: [New drugs for small animals in 2010].

Journal: Tierarztliche Praxis. Ausgabe K, Kleintiere/Heimtiere 20110101

Title: Dronedarone therapy in atrial fibrillation: a summary of recent controlled trials.

Journal: Journal of cardiovascular pharmacology and therapeutics 20101201

Title: Clinical pharmacology of dronedarone: implications for the therapy of atrial fibrillation.

Journal: Journal of cardiovascular pharmacology and therapeutics 20101201

Title: Effect of dronedarone on exercise capacity and cardiac function in patients with severe left ventricular dysfunction and compensated stable heart failure.

Journal: Cardiovascular drugs and therapy 20101201

Title: Dronedarone or amiodarone for rhythm control for atrial fibrillation: implications from the DIONYSOS study.

Journal: Expert opinion on pharmacotherapy 20101201

Title: Treatment of atrial fibrillation in 2010 and beyond.

Journal: Journal of cardiovascular pharmacology and therapeutics 20101201

Title: A new agent for atrial fibrillation: electrophysiological properties of dronedarone.

Journal: Journal of cardiovascular pharmacology and therapeutics 20101201

Title: A review of the appropriate and inappropriate use of dronedarone: lessons learned from controlled studies and regulatory submission.

Journal: Journal of cardiovascular pharmacology and therapeutics 20101201

Title: Augmenting maintenance of sinus rhythm in the control of atrial fibrillation by antiarrhythmic drug combinations.

Journal: Journal of cardiovascular pharmacology and therapeutics 20101201

Title: [Dronedarone].

Journal: Herzschrittmachertherapie & Elektrophysiologie 20101201

Title: [New developments in the antiarrhythmic therapy of atrial fibrillation].

Journal: Herzschrittmachertherapie & Elektrophysiologie 20101201

Title: Are neurological and other side effects truly less frequent in dronedarone compared to amiodarone?

Journal: Journal of cardiovascular electrophysiology 20101201

Title: Advances in the treatment of atrial fibrillation.

Journal: Minerva cardioangiologica 20101201

Title: [Management of atrial fibrillation, what to know on old and new antiarrhythmics].

Journal: Annales de cardiologie et d'angeiologie 20101201

Title: [Current management of atrial fibrillation: rhythm or rate control and thoughts about a new treatment paradigm].

Journal: Annales de cardiologie et d'angeiologie 20101201

Title: Dronedarone for atrial fibrillation?

Journal: Drug and therapeutics bulletin 20101101

Title: Dronedarone for atrial fibrillation have we expanded the antiarrhythmic armamentarium?

Journal: Journal of the American College of Cardiology 20101012

Title: Synergistic effect of the combination of ranolazine and dronedarone to suppress atrial fibrillation.

Journal: Journal of the American College of Cardiology 20101005

Title: New approaches to atrial fibrillation management: treat the patient, not the ECG.

Journal: Cardiovascular therapeutics 20101001

Title: Dronedarone and vitamin K antagonists: a review of drug-drug interactions.

Journal: American heart journal 20101001

Title: Dronedarone for the treatment of atrial fibrillation and atrial flutter.

Journal: Health technology assessment (Winchester, England) 20101001

Title: [Treatment of atrial fibrillation: when to use drugs or to perform ablation].

Journal: Giornale italiano di cardiologia (2006) 20101001

Title: Acute dronedarone is inferior to amiodarone in terminating and preventing atrial fibrillation in canine atria.

Journal: Heart rhythm 20100901

Title: Amiodarone and dronedarone: the worker bee and the drone?

Journal: Heart rhythm 20100901

Title: Worsening heart failure in the setting of dronedarone initiation.

Journal: The Annals of pharmacotherapy 20100901

Title: Role of dronedarone in atrial fibrillation: more questions than answers.

Journal: Pharmacotherapy 20100901

Title: Dronedarone: a new antiarrhythmic agent.

Journal: Pharmacotherapy 20100901

Title: Dronedarone: an alternative to amiodarone?

Journal: The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists 20100901

Title: [Advances in the prevention of cerebral ischaemia due to atrial fibrillation].

Journal: Neurologia (Barcelona, Spain) 20100901

Title: The impact of new and emerging clinical data on treatment strategies for atrial fibrillation.

Journal: Journal of cardiovascular electrophysiology 20100801

Title: Prevention of stroke in patients with atrial fibrillation: the role of new antiarrhythmic and antithrombotic drugs.

Journal: Cerebrovascular diseases (Basel, Switzerland) 20100801

Title: Dronedarone: NICE enough?

Journal: Expert review of cardiovascular therapy 20100801

Title: Dronedarone in patients with atrial fibrillation.

Journal: Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation 20100801

Title: Dronedarone: where does it fit in the treatment of atrial fibrillation?

Journal: South Dakota medicine : the journal of the South Dakota State Medical Association 20100801

Title: Dronedarone. atrial fibrillation: too many questions about long-term adverse effects.

Journal: Prescrire international 20100801

Title: The dronedarone odyssey.

Journal: Prescrire international 20100801

Title: Dronedarone: a safety comparison to amiodarone.

Journal: Current drug safety 20100702

Title: Dronedarone in patients with congestive heart failure: insights from ATHENA.

Journal: European heart journal 20100701

Title: A short-term, randomized, double-blind, parallel-group study to evaluate the efficacy and safety of dronedarone versus amiodarone in patients with persistent atrial fibrillation: the DIONYSOS study.

Journal: Journal of cardiovascular electrophysiology 20100601

Title: Dronedarone: an emerging therapy for atrial fibrillation.

Journal: Therapeutic advances in cardiovascular disease 20100601

Title: A perspective on DIONYSOS.

Journal: Journal of cardiovascular electrophysiology 20100601

Title: Dronedarone: a review of characteristics and clinical data.

Journal: Critical pathways in cardiology 20100601

Title: Thrombi of different pathologies: implications for diagnosis and treatment.

Journal: Current treatment options in cardiovascular medicine 20100601

Title: New and emerging antiarrhythmic and anticoagulant agents for atrial fibrillation.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20100501

Title: Antiarrhythmic and nonantiarrhythmic drugs for sudden cardiac death prevention.

Journal: Journal of cardiovascular pharmacology 20100501

Title: Cost burden of cardiovascular hospitalization and mortality in ATHENA-like patients with atrial fibrillation/atrial flutter in the United States.

Journal: Clinical cardiology 20100501

Title: Dronedarone for atrial fibrillation have we expanded the antiarrhythmic armamentarium?

Journal: Journal of the American College of Cardiology 20100413

Title: New antiarrhythmic drugs for treatment of atrial fibrillation.

Journal: Lancet (London, England) 20100403

Title: Comparative efficacy of dronedarone and amiodarone for the maintenance of sinus rhythm in patients with atrial fibrillation.

Journal: Journal of the American College of Cardiology 20100309

Title: Dronedarone is superior to placebo the case for optimism.

Journal: Journal of the American College of Cardiology 20100309

Title: The role of thyroid hormone nuclear receptors in the heart: evidence from pharmacological approaches.

Journal: Heart failure reviews 20100301

Title: Atrial Ca2+ signaling in atrial fibrillation as an antiarrhythmic drug target.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20100301

Title: Cardioversion of atrial fibrillation: the use of antiarrhythmic drugs.

Journal: Heart (British Cardiac Society) 20100301

Title: [Current antiarrhythmic drug therapy in atrial fibrillation].

Journal: Deutsche medizinische Wochenschrift (1946) 20100301

Title: [Clinical profile of the new antiarrhythmic drug dronedarone].

Journal: Deutsche medizinische Wochenschrift (1946) 20100301

Title: [Clinical pharmacology and electrophysiological properties of dronedarone].

Journal: Deutsche medizinische Wochenschrift (1946) 20100301

Title: [Preventing stroke by treating atrial fibrillation--new hope with dronedarone and dabigatran?].

Journal: Deutsche medizinische Wochenschrift (1946) 20100301

Title: FDA drug information that never reaches clinicians.

Journal: The New England journal of medicine 20100211

Title: Replacing aspirin and warfarin for secondary stroke prevention: is it worth the costs?

Journal: Current opinion in neurology 20100201

Title: Atrial fibrillation. DIONYSOS study comparing dronedarone with amiodarone.

Journal: BMJ (Clinical research ed.) 20100119

Title: Dronedarone: a novel antiarrhythmic agent for the treatment of atrial fibrillation.

Journal: Current opinion in cardiology 20100101

Title: Effects of amiodarone therapy on thyroid function.

Journal: Nature reviews. Endocrinology 20100101

Title: Efficacy and safety of dronedarone: a review of randomized trials.

Journal: Expert opinion on drug safety 20100101

Title: Dronedarone--a new alternative for management of atrial fibrillation.

Journal: Recent patents on cardiovascular drug discovery 20100101

Title: Atrial fibrillation: Dronedarone and amiodarone-the safety versus efficacy debate.

Journal: Nature reviews. Cardiology 20100101

Title: Dronedarone: current evidence and future questions.

Journal: Cardiovascular therapeutics 20100101

Title: [Comparison of dronedarone and amiodarone for the maintenance of sinus rhythm in patients with atrial fibrillation. Indirect meta-analysis].

Journal: Kardiologiia 20100101

Title: Impact of dronedarone in atrial fibrillation and flutter on stroke reduction.

Journal: Clinical interventions in aging 20100101

Title: Forecasting drug utilization and expenditure in a metropolitan health region.

Journal: BMC health services research 20100101

Title: Significant sirolimus and dronedarone interaction in a kidney transplant recipient.

Journal: The Annals of pharmacotherapy 20100101

Title: Concept of the five 'A's for treating emergency arrhythmias.

Journal: Journal of emergencies, trauma, and shock 20100101

Title: Treating critical supraventricular and ventricular arrhythmias.

Journal: Journal of emergencies, trauma, and shock 20100101

Title: Beta1-adrenoceptor polymorphism predicts flecainide action in patients with atrial fibrillation.

Journal: PloS one 20100101

Title: [Ionic mechanisms of action of class III antiarrhythmic drugs].

Journal: Kardiologiia 20100101

Title: Amiodarone for the treatment and prevention of ventricular fibrillation and ventricular tachycardia.

Journal: Vascular health and risk management 20100101

Title: Dronedarone for the treatment of atrial fibrillation and atrial flutter: approval and efficacy.

Journal: Vascular health and risk management 20100101

Title: Atrial fibrillation after cardiac surgery.

Journal: Annals of cardiac anaesthesia 20100101

Title: Dronedarone: evidence supporting its therapeutic use in the treatment of atrial fibrillation.

Journal: Core evidence 20100101

Title: Dronedarone: from buzz to reality.

Journal: Archives of cardiovascular diseases 20100101

Title: [New antiarrhythmic drugs for treatment of atrial fibrillation].

Journal: Duodecim; laaketieteellinen aikakauskirja 20100101

Title: [Novel targets in the treatment of patients with atrial fibrillation: from elimination of symptoms to improvement of clinical outcomes].

Journal: Kardiologiia 20100101

Title: The effect of acyclovir on the tubular secretion of creatinine in vitro.

Journal: Journal of translational medicine 20100101

Title: Dronedarone: a new therapeutic alternative for cardiac arrhythmias.

Journal: Journal of young pharmacists : JYP 20100101

Title: Amiodarone and thyroid.

Journal: Best practice & research. Clinical endocrinology & metabolism 20091201

Title: Recent advances in the pharmacological treatment of cardiac arrythmias.

Journal: Drugs of today (Barcelona, Spain : 1998) 20091101

Title: Dronedarone (Multaq) for atrial fibrillation.

Journal: The Medical letter on drugs and therapeutics 20091005

Title: Dronedarone: a promising alternative for the management of atrial fibrillation.

Journal: Cardiovascular drugs and therapy 20091001

Title: Rethinking the reasons to treat atrial fibrillation? The role of dronedarone in reducing cardiovascular hospitalizations.

Journal: European heart journal 20091001

Title: Dronedarone.

Journal: Nature reviews. Drug discovery 20091001

Title: New pharmacological agents for arrhythmias.

Journal: Circulation. Arrhythmia and electrophysiology 20091001

Title: New and emerging antiarrhythmic drugs for atrial fibrillation: what may become available to the clinician in the near future.

Journal: Current treatment options in cardiovascular medicine 20091001

Title: Analysis of stroke in ATHENA: a placebo-controlled, double-blind, parallel-arm trial to assess the efficacy of dronedarone 400 mg BID for the prevention of cardiovascular hospitalization or death from any cause in patients with atrial fibrillation/atrial flutter.

Journal: Circulation 20090929

Title: Comparative efficacy of dronedarone and amiodarone for the maintenance of sinus rhythm in patients with atrial fibrillation.

Journal: Journal of the American College of Cardiology 20090915

Title: Amiodarone or dronedarone for atrial fibrillation: too early to know the winner?

Journal: Journal of the American College of Cardiology 20090915

Title: Dronedarone.

Journal: Drugs 20090820

Title: Dronedarone.

Journal: Circulation 20090818

Title: Dronedarone approved for atrial arrhythmias.

Journal: American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20090815

Title: Pharmacologic management of atrial fibrillation: established and emerging options.

Journal: Journal of managed care pharmacy : JMCP 20090801

Title: Recent advances in pharmacotherapy of atrial fibrillation.

Journal: Indian journal of pharmacology 20090801

Title: Determination of the class III antiarrhythmic drugs dronedarone and amiodarone, and their principal metabolites in plasma and myocardium by high-performance liquid chromatography and UV-detection.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090615

Title: Dronedarone in atrial fibrillation.

Journal: The New England journal of medicine 20090604

Title: Dronedarone in atrial fibrillation.

Journal: The New England journal of medicine 20090604

Title: Dronedarone in atrial fibrillation.

Journal: The New England journal of medicine 20090604

Title: Dronedarone in atrial fibrillation.

Journal: The New England journal of medicine 20090604

Title: [Dronedarone: the new antiarrythmic agent?].

Journal: Herzschrittmachertherapie & Elektrophysiologie 20090601

Title: New pharmacological options for patients with atrial fibrillation: the ATHENA trial.

Journal: Revista espanola de cardiologia 20090501

Title: Antiarrhythmic drugs for atrial fibrillation: focus on dronedarone.

Journal: Expert review of cardiovascular therapy 20090501

Title: Dronedarone for atrial fibrillation--an odyssey.

Journal: The New England journal of medicine 20090430

Title: A preliminary assessment of the effects of ATI-2042 in subjects with paroxysmal atrial fibrillation using implanted pacemaker methodology.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20090401

Title: Alternatives to amiodarone: search for the Holy Grail.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20090401

Title: Trial watch: novel antiarrhythmic agent shows promise in Phase III trial.

Journal: Nature reviews. Drug discovery 20090401

Title: [The effect of dronedarone on the frequency of cardiovascular events in patients with atrial fibrillation - ATHENA studies].

Journal: Kardiologia polska 20090401

Title: Major recent trials in cardiovascular diseases.

Journal: Postgraduate medicine 20090301

Title: Effect of dronedarone on cardiovascular events in atrial fibrillation.

Journal: The New England journal of medicine 20090212

Title: Clinical trials update from the Heart Failure Society of America and the American Heart Association meetings in 2008: SADHART-CHF, COMPARE, MOMENTUM, thyroid hormone analogue study, HF-ACTION, I-PRESERVE, beta-interferon study, BACH, and ATHENA.

Journal: European journal of heart failure 20090201

Title: Benzofuran derivatives and the thyroid.

Journal: Clinical endocrinology 20090101

Title: Atrial-selective pharmacological therapy for atrial fibrillation: hype or hope?

Journal: Current opinion in cardiology 20090101

Title: Novel approaches for pharmacological management of atrial fibrillation.

Journal: Drugs 20090101

Title: [How did ATHENA win ANDROMEDA? Results of the ATHENA].

Journal: Kardiologiia 20090101

Title: Molecular genetics of atrial fibrillation.

Journal: Genome medicine 20090101

Title: Atrial fibrillation: from ion channels to bedside treatment options.

Journal: Journal of electrocardiology 20090101

Title: [Treatment of atrial fibrillation in heart failure].

Journal: Therapie 20090101

Title: Dronedarone for atrial fibrillation: a new therapeutic agent.

Journal: Vascular health and risk management 20090101

Title: Dronedarone: a new antiarrhythmic agent for the treatment of atrial fibrillation.

Journal: Cardiology in review 20090101

Title: Prasugrel hydrochloride, dronedarone, and saxagliptin hydrochloride.

Journal: Journal of the American Pharmacists Association : JAPhA 20090101

Title: Can we improve outcomes in AF patients by early therapy?

Journal: BMC medicine 20090101

Title: New advances and new questions in cardiovascular therapeutics.

Journal: American journal of therapeutics 20090101

Title: Advances in the management of atrial fibrillation in congestive heart failure.

Journal: F1000 medicine reports 20090101

Title: [Amiodaron for treatment of perioperative cardiac arrythmia: a broad spectrum antiarrythmetic agent?].

Journal: Der Anaesthesist 20081201

Title: Dronedarone: a new treatment for atrial fibrillation.

Journal: Journal of cardiovascular electrophysiology 20081101

Title: New antiarrhythmic drugs for atrial fibrillation: focus on dronedarone and vernakalant.

Journal: Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing 20081001

Title: Amiodarone as paradigm for developing new drugs for atrial fibrillation.

Journal: Journal of cardiovascular pharmacology 20081001

Title: New horizons in antiarrhythmic therapy: will novel agents overcome current deficits?

Journal: The American journal of cardiology 20080922

Title: Clinical trials update from Heart Rhythm 2008 and Heart Failure 2008: ATHENA, URGENT, INH study, HEART and CK-1827452.

Journal: European journal of heart failure 20080901

Title: Dronedarone for the control of ventricular rate in permanent atrial fibrillation: the Efficacy and safety of dRonedArone for the cOntrol of ventricular rate during atrial fibrillation (ERATO) study.

Journal: American heart journal 20080901

Title: [Current pharmacological management of atrial fibrillation management by practice cardiologists - news from congress in Munich].

Journal: Kardiologia polska 20080901

Title: Increased mortality after dronedarone therapy for severe heart failure.

Journal: The New England journal of medicine 20080619

Title: Acute inhibitory effect of dronedarone, a noniodinated benzofuran analogue of amiodarone, on Na+/Ca2+ exchange current in guinea pig cardiac ventricular myocytes.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20080601

Title: Pharmacotherapy for atrial arrhythmias: present and future.

Journal: Heart rhythm 20080601

Title: Anti-arrhythmic drug therapy for atrial fibrillation: current anti-arrhythmic drugs, investigational agents, and innovative approaches.

Journal: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20080601

Title: Concurrent Chagas' disease and borderline disseminated cutaneous leishmaniasis: The role of amiodarone as an antitrypanosomatidae drug.

Journal: Therapeutics and clinical risk management 20080601

Title: Is dronedarone effective for the prevention of recurrent atrial fibrillation?

Journal: Nature clinical practice. Cardiovascular medicine 20080301

Title: Update on atrial fibrillation: part II.

Journal: Clinical cardiology 20080301

Title: Rationale and design of ATHENA: A placebo-controlled, double-blind, parallel arm Trial to assess the efficacy of dronedarone 400 mg bid for the prevention of cardiovascular Hospitalization or death from any cause in patiENts with Atrial fibrillation/atrial flutter.

Journal: Journal of cardiovascular electrophysiology 20080101

Title: Relationship among amiodarone, new class III antiarrhythmics, miscellaneous agents and acquired long QT syndrome.

Journal: Cardiology journal 20080101

Title: [Efficacy of dronedarone for maintenance of sinus rhythm in atrial fibrillation or flutter. Results of the EURIDIS and ADONIS].

Journal: Kardiologiia 20080101

Title: Atrial fibrillation after cardiac surgery: where are we now?

Journal: Indian pacing and electrophysiology journal 20080101

Title: [Efficacy of dronedarone in cardiac failure due to severe left ventricular systolic dysfunction. Results of the ANDROMEDA].

Journal: Kardiologiia 20080101

Title: Dronedarone in atrial fibrillation.

Journal: The New England journal of medicine 20071206

Title: Dronedarone in atrial fibrillation.

Journal: The New England journal of medicine 20071206

Title: Effect of dronedarone on renal function in healthy subjects.

Journal: British journal of clinical pharmacology 20071201

Title: In vitro effects of acute amiodarone and dronedarone on epicardial, endocardial, and M cells of the canine ventricle.

Journal: Journal of cardiovascular pharmacology and therapeutics 20071201

Title: New antiarrhythmic drugs for establishing sinus rhythm in atrial fibrillation: what are our therapies likely to be by 2010 and beyond?

Journal: American heart journal 20071101

Title: Antiarrhythmics for maintaining sinus rhythm after cardioversion of atrial fibrillation.

Journal: The Cochrane database of systematic reviews 20071017

Title: Dronedarone for maintenance of sinus rhythm in atrial fibrillation or flutter.

Journal: The New England journal of medicine 20070906

Title: Maintaining sinus rhythm--making treatment better than the disease.

Journal: The New England journal of medicine 20070906

Title: Acute in vitro effects of dronedarone, an iodine-free derivative, and amiodarone, on the rabbit sinoatrial node automaticity: a comparative study.

Journal: Journal of cardiovascular pharmacology and therapeutics 20070901

Title: Na+/Ca2+ exchange inhibitors: a new class of calcium regulators.

Journal: Cardiovascular & hematological disorders drug targets 20070901

Title: Inhibition of the HERG potassium channel by the tricyclic antidepressant doxepin.

Journal: Biochemical pharmacology 20070801

Title: New antiarrhythmic treatment of atrial fibrillation.

Journal: Expert review of cardiovascular therapy 20070701

Title: Comparative antiarrhythmic efficacy of amiodarone and dronedarone during acute myocardial infarction in rats.

Journal: European journal of pharmacology 20070614

Title: Effect of amiodarone and dronedarone administration in rats on thyroid hormone-dependent gene expression in different cardiac components.

Journal: European journal of endocrinology 20070601

Title: Dronedarone: an amiodarone analog for the treatment of atrial fibrillation and atrial flutter.

Journal: The Annals of pharmacotherapy 20070401

Title: A review of the investigational antiarrhythmic agent dronedarone.

Journal: Journal of cardiovascular pharmacology and therapeutics 20070301

Title: Pharmacological inhibition of TRalpha1 receptor potentiates the thyroxine effect on body weight reduction in rats: potential therapeutic implications in controlling body weight.

Journal: Diabetes, obesity & metabolism 20070101

Title: Dronedarone: drondarone, SR 33589, SR 33589B.

Journal: Drugs in R&D 20070101

Title: Dronedarone: in quest of the ideal antiarrhythmic drug.

Journal: Progress in cardiovascular nursing 20070101

Title: Comment on dronedarone.

Journal: Journal of cardiovascular electrophysiology 20061201

Title: Do we need pharmacological therapy for atrial fibrillation in the ablation era?

Journal: Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing 20061201

Title: Dronedarone: an emerging agent with rhythm- and rate-controlling effects.

Journal: Journal of cardiovascular electrophysiology 20060901

Title: Medical management of atrial fibrillation: state of the art.

Journal: Journal of cardiovascular electrophysiology 20060901

Title: Amiodarone: a multifaceted antiarrhythmic drug.

Journal: Current cardiology reports 20060901

Title: Topics on the Na+/Ca2+ exchanger: pharmacological characterization of Na+/Ca2+ exchanger inhibitors.

Journal: Journal of pharmacological sciences 20060901

Title: Drug evaluation: dronedarone, a novel non-iodinated anti-arrhythmic agent.

Journal: Current opinion in investigational drugs (London, England : 2000) 20060901

Title: Dose-dependent effects of oral dronedarone on the circadian variation of RR and QT intervals in healthy subjects: implications for antiarrhythmic actions.

Journal: Journal of cardiovascular pharmacology and therapeutics 20060901

Title: [Dronedarone--a new therapeutic option for controlling atrial rhythm and ventricular frequency].

Journal: Deutsche medizinische Wochenschrift (1946) 20060825

Title: [Dronedarone establishes and maintains control of sinus rhythm].

Journal: Revue medicale suisse 20060823

Title: Amiodarone inhibits thyroidal iodide transport in vitro by a cyclic adenosine 5'-monophosphate- and iodine-independent mechanism.

Journal: Endocrinology 20060601

Title: Dronedarone: a new antiarrhythmic agent.

Journal: Drugs of today (Barcelona, Spain : 1998) 20060201

Title: Pharmacological treatment of atrial fibrillation: mechanisms of action and efficacy of class III drugs.

Journal: Current medicinal chemistry 20060101

Title: This DAFNE is definitely not that DAFNE.

Journal: International journal of cardiology 20050525

Title: [Safety of new anti-arrhythmic drugs].

Journal: Archives des maladies du coeur et des vaisseaux 20050401

Title: A review of the pharmacokinetics, electrophysiology and clinical efficacy of dronedarone.

Journal: Future cardiology 20050301

Title: In vivo and in vitro antiarrhythmic effects of SSR149744C in animal models of atrial fibrillation and ventricular arrhythmias.

Journal: Journal of cardiovascular pharmacology 20050201

Title: Dronedarone administration prevents body weight gain and increases tolerance of the heart to ischemic stress: a possible involvement of thyroid hormone receptor alpha1.

Journal: Thyroid : official journal of the American Thyroid Association 20050101

Title: [Atrial fibrillation: choice of the method of pharmacological cardioversion].

Journal: Kardiologiia 20050101

Title: The novel antiarrhythmic drug dronedarone: comparison with amiodarone.

Journal: Cardiovascular drug reviews 20050101

Title: Antiarrhythmic drugs in patients with implantable cardioverter-defibrillators.

Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20050101

Title: High affinity HERG K(+) channel blockade by the antiarrhythmic agent dronedarone: resistance to mutations of the S6 residues Y652 and F656.

Journal: Biochemical and biophysical research communications 20041217

Title: A benefit-risk assessment of class III antiarrhythmic agents.

Journal: Expert opinion on drug safety 20041101

Title: [New anti-arrhythmics--hope or disappointment?].

Journal: Archives des maladies du coeur et des vaisseaux 20041101

Title: Involvement of nitric oxide in amiodarone- and dronedarone-induced coronary vasodilation in guinea pig heart.

Journal: European journal of pharmacology 20040802

Title: Effects of metabolites and analogs of amiodarone on alveolar macrophages: structure-activity relationship.

Journal: American journal of physiology. Lung cellular and molecular physiology 20040801

Title: Dronedarone: an amiodarone analogue.

Journal: Expert opinion on investigational drugs 20040401

Title: Pharmacokinetic and pharmacodynamic interactions between metoprolol and dronedarone in extensive and poor CYP2D6 metabolizers healthy subjects.

Journal: Fundamental & clinical pharmacology 20040201

Title: Oral class III antiarrhythmics: what is new?

Journal: Current opinion in cardiology 20040101

Title: Trials of new antiarrhythmic drugs for maintenance of sinus rhythm in patients with atrial fibrillation.

Journal: Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing 20040101

Title: Theoretical possibilities for the development of novel antiarrhythmic drugs.

Journal: Current medicinal chemistry 20040101

Title: Acute effects of dronedarone on both components of the cardiac delayed rectifier K+ current, HERG and KvLQT1/minK potassium channels.

Journal: British journal of pharmacology 20031101

Title: IKr channel blockers: novel antiarrhythmic agents.

Journal: Current medicinal chemistry. Cardiovascular and hematological agents 20031001

Title: Effects of amiodarone and dronedarone on voltage-dependent sodium current in human cardiomyocytes.

Journal: Journal of cardiovascular electrophysiology 20030801

Title: Dronedarone for prevention of atrial fibrillation: a dose-ranging study.

Journal: European heart journal 20030801

Title: Old and new antiarrhythmic drugs for converting and maintaining sinus rhythm in atrial fibrillation: comparative efficacy and results of trials.

Journal: The American journal of cardiology 20030320

Title: Dronerarone acts as a selective inhibitor of 3,5,3'-triiodothyronine binding to thyroid hormone receptor-alpha1: in vitro and in vivo evidence.

Journal: Endocrinology 20030201

Title: Electrophysiologic characterization of dronedarone in guinea pig ventricular cells.

Journal: Journal of cardiovascular pharmacology 20030201

Title: Chronic amiodarone-induced inhibition of the Na+-K+ pump in rabbit cardiac myocytes is thyroid-dependent: comparison with dronedarone.

Journal: Cardiovascular research 20030101

Title: The JT-area indicates dispersion of repolarization in dogs with atrioventricular block.

Journal: Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing 20020601

Title: Effects of dronedarone and amiodarone on plasma thyroid hormones and on the basal and postischemic performance of the isolated rat heart.

Journal: European journal of pharmacology 20020531

Title: Chronic and acute effects of dronedarone on the action potential of rabbit atrial muscle preparations: comparison with amiodarone.

Journal: Journal of cardiovascular pharmacology 20020501

Title: Recent advances in arrhythmia therapy: treatment and prevention of atrial fibrillation.

Journal: Current opinion in pharmacology 20020401

Title: New antiarrhythmic drugs for the treatment of atrial fibrillation.

Journal: Pacing and clinical electrophysiology : PACE 20020201

Title: Five novel single nucleotide polymorphisms in the CYP2C8 gene, one of which induces a frame-shift.

Journal: Drug metabolism and pharmacokinetics 20020101

Title: Chronic amiodarone evokes no torsade de pointes arrhythmias despite QT lengthening in an animal model of acquired long-QT syndrome.

Journal: Circulation 20011127

Title: Beneficial effects of amiodarone and dronedarone (SR 33589b), when applied during low-flow ischemia, on arrhythmia and functional parameters asssessed during reperfusion in isolated rat hearts.

Journal: Journal of cardiovascular pharmacology 20011001

Title: Electrophysiological effects of dronedarone (SR 33589), a noniodinated amiodarone derivative in the canine heart: comparison with amiodarone.

Journal: British journal of pharmacology 20010701

Title: Dronedarone (Sanofi-Synthélabo).

Journal: IDrugs : the investigational drugs journal 20010501

Title: Mechanisms of action of antiarrhythmic drugs relative to the origin and perpetuation of cardiac arrhythmias.

Journal: Journal of cardiovascular pharmacology and therapeutics 20010101

Title: Newer antiarrhythmic drugs.

Journal: Indian heart journal 20010101

Title: Hemodynamic and antiadrenergic effects of dronedarone and amiodarone in animals with a healed myocardial infarction.

Journal: Journal of cardiovascular pharmacology 20000901

Title: Chinmay Patel, et al. Dronedarone. Circulation. 2009 Aug 18;120(7):636-44.

Title: Katarzyna M Sawicka, et al. Influence of dronedarone (a class III antiarrhythmic drug) on the anticonvulsant potency of four classical antiepileptic drugs in the tonic-clonic seizure model in mice. J Neural Transm (Vienna). 2019 Feb;126(2):115-122.

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Tags:141626-36-0 Molecular Formula|141626-36-0 MDL|141626-36-0 SMILES|141626-36-0 Dronedarone