Home Other Building Blocks 1435934-25-0
1435934-25-0,MFCD19690922
Catalog No.:AA00AQ9A

1435934-25-0 | RK 20449 trihydrochloride

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥95%
in stock  
$63.00   $44.00
- +
5mg
≥95%
in stock  
$230.00   $161.00
- +
10mg
≥95%
in stock  
$428.00   $299.00
- +
25mg
≥95%
in stock  
$989.00   $692.00
- +
50mg
≥98%(HPLC)
in stock  
$1,311.00   $918.00
- +
  • Technical Information
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA00AQ9A
Chemical Name:
RK 20449 trihydrochloride
CAS Number:
1435934-25-0
Molecular Formula:
C29H37Cl3N6O
Molecular Weight:
592.0027
MDL Number:
MFCD19690922
SMILES:
CN1CCN(CC1)C1CCC(CC1)n1cc(c2c1ncnc2N)c1ccc(cc1)Oc1ccccc1.Cl.Cl.Cl
Properties
Computed Properties
 
Complexity:
679  
Covalently-Bonded Unit Count:
4  
Heavy Atom Count:
39  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
5  

Literature

Title: An inhibitor-resistant mutant of Hck protects CML cells against the antiproliferative and apoptotic effects of the broad-spectrum Src family kinase inhibitor A-419259.

Journal: Oncogene 20081127

Title: Selective pyrrolo-pyrimidine inhibitors reveal a necessary role for Src family kinases in Bcr-Abl signal transduction and oncogenesis.

Journal: Oncogene 20021121

Title: Differential effects of phenobarbital and pentobarbital on isolated nervous tissue.

Journal: Epilepsia 19751101

Title: Wilson MB, et al. Selective pyrrolo-pyrimidine inhibitors reveal a necessary role for Src family kinases in Bcr-Abl signal transduction and oncogenesis. Oncogene. 2002 Nov 21;21(53):8075-88.

Title: Pene-Dumitrescu T, et al. An inhibitor-resistant mutant of Hck protects CML cells against the antiproliferative and apoptotic effects of the broad-spectrum Src family kinase inhibitor A-419259.Oncogene (2008) 27, 7055-7069

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Tags:1435934-25-0 Molecular Formula|1435934-25-0 MDL|1435934-25-0 SMILES|1435934-25-0 RK 20449 trihydrochloride